Patents Examined by Lyle A. Alexander
  • Patent number: 9718059
    Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 1, 2017
    Assignee: GEN-PROBE INCORPORATED
    Inventors: David Buse, Byron J. Knight, Julian Groeli
  • Patent number: 9715998
    Abstract: The invention discloses a method for monitoring level of paraben comprising: dissolving a sample in a solvent and obtaining a supernatant containing paraben by ultrasonic vibration and high speed centrifugation; performing a derivatization reaction between a derivatization reagent and paraben by adding the derivatization reagent into the supernatant to obtain a derivatization solution containing a tagged paraben; extracting the derivatization solution by an extractant to obtain an extract containing the tagged paraben; and ionizating the tagged paraben by a laser beam and analyzing mass-to-charge ratio of the tagged paraben by an analyzer to determine molecular weight thereof.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: July 25, 2017
    Assignee: Kaohsuing Medical University
    Inventors: Chi-Yu Lu, Yi-Hsuan Lee
  • Patent number: 9696261
    Abstract: A multi-channel device includes up to three channels for optical testing of liquid samples. The liquid sample(s) may include surface water, drinking water, processed water or the like. The multi-channel device may include a turbidity channel and a color channel that measure turbidity and color, respectively, of a liquid sample using spectrographic analysis. The multi-channel device may also include a colorimetric channel that measures the concentration of various analytes in a liquid sample, such as free chlorine, total chlorine, copper and phosphate.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: July 4, 2017
    Assignee: Ecolab USA Inc.
    Inventors: Eugene Tokhtuev, Christopher J. Owen, Viktor Slobodyan, William M. Christensen, Paul Schilling, Joseph Phillip Erickson
  • Patent number: 9687754
    Abstract: A system for extracting oil from oil-bearing plant parts has an extraction vessel supported by an upright stand, a separator vessel mounted below the extraction vessel, and an expansion filter vessel mounted downstream from the separator vessel. A source of hydrocarbon solvent supplies liquid gas to the top of the extraction vessel, while a recycling pump connected to the separator vessel facilitates transport of the solvent through the plant material in the extraction vessel. The solvent is recovered and re-circulated, while extracted oil is removed from the separator. A computer-based temperature control assembly having a cooling device and a jacketed injection coil regulates temperature of the solvent delivered to the extraction assembly. A thermal jacket is mounted on each of the separator vessel and the expansion filter vessel, with the thermal jackets supplying heat and cold to the interior of the separator vessel and the expansion filter vessel and helping evaporate and condense the solvent.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: June 27, 2017
    Inventor: Matthew Ellis
  • Patent number: 9643181
    Abstract: A microfluidic system-on-a-chip includes signal processing, light generation and detection, and fluid handling functions formed on a single substrate. The disclosed integrated system has a smaller footprint than device structures where individual components are manufactured separately and then assembled. Moreover, the integrated system obviates alignment challenges associated with conventionally packaged architecture.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: May 9, 2017
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Hung-Yang Chang, Ning Li, Fei Liu, Qiqing C. Ouyang, Seshadri Subbanna, Yajuan Wang
  • Patent number: 9588113
    Abstract: An improved qualitative or semi-quantitative diagnostic test for low levels of any analyte, such as hCG, in a biological sample, such as urine. The test comprises of a test device containing reagents for the detection of the monitored analyte and an electronic reader that measures color development at a detection area of the device. The color development is converted to an electronic or digital signal. Improvements were made to the detection process to optimize the detection of a valid fluid front, increase the detection limit without compromising the reliability and accuracy of the test system, and improve the determination of test result validity.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: March 7, 2017
    Assignee: Church & Dwight Co., Inc.
    Inventors: Albert R. Nazareth, Andy Sturman, Benedict Zin
  • Patent number: 9588133
    Abstract: A method is provided for disposing of a liquid within an automated analytical system for processing a fluid biological sample, wherein a contamination prevention shield including channels for pipets or pipet tips is reversibly docked to a container for liquid waste in order to reduce the risk of cross-contamination. A tip rack assembly is provided for processing a fluid sample, the assembly including a rack for pipet tips and the contamination prevention shield. An analytical system is provided using the tip rack assembly, wherein cross-contamination is avoided.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: March 7, 2017
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Renato Belz, Christian Thalmann
  • Patent number: 9588103
    Abstract: A method of analyzing biological particles for a biological particle analyzer includes outputting a first detection result when at least one particle has arrived at the first detection area, outputting a second detection result to the control module when the particles have arrived at the second detection area, and determining when to turn on or off the light emission source and outputting a control signal to turn on or off the light emission source according to the first detection result, wherein a control module is configured to calculate a turn-on time according to different particle characteristics and an average velocity of the at least one particle, and the light emission source is turned on only when the at least one particle is being tested during the turn-on time.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: March 7, 2017
    Assignee: Wistron Corporation
    Inventors: Chun-Chih Lai, Ting-Wen Liu
  • Patent number: 9579649
    Abstract: Embodiments of fluid distribution manifolds, cartridges, and microfluidic systems are described herein. Fluid distribution manifolds may include an insert member and a manifold base and may define a substantially closed channel within the manifold when the insert member is press-fit into the base. Cartridges described herein may allow for simultaneous electrical and fluidic interconnection with an electrical multiplex board and may be held in place using magnetic attraction.
    Type: Grant
    Filed: October 7, 2010
    Date of Patent: February 28, 2017
    Assignee: Sandia Corporation
    Inventors: Ronald F. Renzi, Gregory J. Sommer, Anup K. Singh, Anson V. Hatch, Mark R. Claudnic, Ying-Chih Wang, James L. Van de Vreugde
  • Patent number: 9574978
    Abstract: Disclosed therein is a sampler. The sampler includes: a chamber accommodating a fluid or solid reagent therein and being sealed at both ends with penetrable films; a tube joined with the chamber at one side, the tube having a hollow portion therein; and a movable bar having a tip which is formed at one end and has a specimen extracting portion, the tip being guided and moved through a hollow portion, the tip being adapted for mixing the specimen extracted by the specimen extracting portion with the reagent so as to form a diluted solution while penetrating through one end of the chamber and adapted for quantitatively discharging out the diluted solution while penetrating through the other end of the chamber.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: February 21, 2017
    Assignee: NANOENTEK, INC.
    Inventors: Dae-Sung Hur, Ji-Young Park
  • Patent number: 9566582
    Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: February 14, 2017
    Assignee: GEN-PROBE INCORPORATED
    Inventors: David Buse, Byron J. Knight
  • Patent number: 9562915
    Abstract: A breath analyzer is described with at least one chemical sensor sensitive to the concentration of a component in a sample of exhaled breath including a compensator for compensating for the effect of variations in the amount of exhaled breath between the user and the sensor location with the chemical sensor being integrated into a portable electronic device, particularly with the sensor being located in an air duct with an opening to the exterior of the housing of the analyzer with the total area of the opening being sufficiently small to restrict effectively mass transport between the exterior and the sensor and/or wherein the compensation includes the compensation for different responses of sensors.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: February 7, 2017
    Assignee: Sensirion AG
    Inventors: Lukas Burgi, Felix Mayer, Frank Roeck
  • Patent number: 9548184
    Abstract: A microreactor for use in a microscope, comprising a first and second cove layer (13), which cover layers are both at least partly transparent to an electron beam (14) of an electron microscope, and extend next to each other at a mutual distance from each other and between which a chamber (15) is enclosed, wherein an inlet (4) and an outlet (5) are provided for feeding fluid through the chamber and wherein heating means (8) are provided for heating the chamber and/or elements present therein.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: January 17, 2017
    Assignees: Technische Universiteit Delft, Stichting voor de Technische Wetenschappen
    Inventors: Jan Fredrik Creemer, Hendrik Willem Zandbergen, Pasqualina Maria Sarro
  • Patent number: 9546935
    Abstract: Specimen collection slides, methods of fabricating and methods of utilizing such specimen collection slides whereby each specimen collection slide includes a top rigid layer with an opening, a bottom rigid layer with an opening substantially the same size as the top layer opening, a middle rigid section having an opening larger than the openings in both the top and bottom layers, and a filtration media residing within the opening in the middle section. The top, bottom and middle are secured together to provide the resultant slide with thickness and rigidity that lends the slide to be utilized in automated handling processes and instruments. The middle section of the slide encases the filtration media and sandwiches it between the top and bottom layers so that the filtration media is protected from damage. Each slide may have its own unique identifier.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: January 17, 2017
    Inventor: Thomas W. Astle
  • Patent number: 9541287
    Abstract: An automatic cleaning assembly for an analytical furnace is detachable from the filter chamber above the combustion tube. The cleaning assembly includes a rotating brush which is lowered through the filter chamber and into the combustion tube while a vacuum is drawn through the lower seal of the combustion tube. This results in a higher vacuum pressure differential and improved flow rate for removing dust from the filter of the furnace and the combustion tube.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: January 10, 2017
    Assignee: Leco Corporation
    Inventors: Gordon C. Ford, Joshua N. Wetzel, Kevin R. Brushwyler
  • Patent number: 9534078
    Abstract: A method for measuring the thermal stability of succinic acid includes the following steps: 1) preparing a succinic acid crystal powder having less than 1% residual water content; 2) placing 10 g of the crystal powder in an oven at 220° C. for 2 hours; 3) pulverizing and sieving the crystal powder processed in this way, such that the particle size distribution thereof is between 0 and 10%, and preferably between 4 and 6% for particles larger than 500 ?m in size, between 20 and 40%, and preferably between 25 and 35% for particles between 200 and 500 ?m in size, between 50 and 75% and preferably between 55 and 70% for particles smaller than 200 ?m in size; and 4) measuring the color, in a spectrocolorimeter, of the pulverized and sieved powder and determining the average value of the yellow (index “b”).
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: January 3, 2017
    Assignee: ROQUETTE FRERES
    Inventors: Guillaume Fiey, Marilyne Guillemant, Jean-Michel Roturier, Nicolas Jacquel
  • Patent number: 9527080
    Abstract: System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 27, 2016
    Assignee: GEN-PROBE INCORPORATED
    Inventors: Byron J. Knight, Julian Groeli
  • Patent number: 9518969
    Abstract: In order to completely decompose remaining urea contained in exhaust gas emitted from an internal combustion engine to make it possible to accurately measure an amount of the remaining urea, as well as preventing measurement accuracy and reliability from being damaged by some cause such as the attachment of powdery urea on a sensor, a gas analysis apparatus is provided with a filter part that is provided between a sampling port and a produced substance measuring mechanism in a mixed gas sampling pipe to collect urea in a solid state or in a state of being dissolved in water in mixed gas.
    Type: Grant
    Filed: September 3, 2012
    Date of Patent: December 13, 2016
    Assignee: Horiba, Ltd.
    Inventor: Shigeru Nakatani
  • Patent number: 9513224
    Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: December 6, 2016
    Assignee: Theranos, Inc.
    Inventors: Karan Mohan, Chinmay Pangarkar, James Wasson
  • Patent number: 9492826
    Abstract: The invention relates to methods and devices for control of an integrated thin-film device with a plurality of microfluidic channels. In one embodiment, the microfluidic device includes a microfluidic chip comprising a first zone having a plurality of microfluidic channels and a second zone having a plurality of microfluidic channels, wherein the microfluidic channels in the first and second zones are in fluid communication. The microfluidic device further comprising a thin-film heater in thermal communication with each of the microfluidic channels in the first and second zones. The microfluidic device also includes a control system configured to independently control the temperature of each of the thin-film heaters using pulse width modulation (PWM) control signals that are optimized for each of the thin-film heaters.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: November 15, 2016
    Assignee: Canon U.S. Life Sciences, Inc.
    Inventors: Takayoshi Hanagata, Hiroshi Inoue, Gregory A. Dale, Kenton C. Hasson