Abstract: A receiver module of an autonomous implanted capsule receives a human body communication, HBC, signal sensed by an electrode in contact with body tissues or fluids of a patient. The signal is a pulse-modulated, baseband PPM pulse signal. The receiver module comprises a non-linear LNA amplifier stage comprising a pair of complementary transistors arranged as a voltage inverter circuit with an input coupled to the modulated-input-signal collecting electrode. The amplifier stage input is polarized to an intermediate operating point voltage between a supply voltage of the complementary transistor pair and a ground voltage. The amplifier stage has a gain of at least 40 dB, a gain-bandwidth product of at least 20 MHz, and a consumption lower than or equal to 100 nW.

Abstract: Systems and methods for His bundle pacing using a stimulation device include applying an impulse to a His bundle of a patient heart using the stimulation device. The stimulation device then measures a response of the patient heart to application of the impulse that includes a response of a ventricle of the patient heart. The stimulation device calculates a ventricular delay as a time from application of the impulse to onset of the response of the ventricle and delivers, using a lead of the stimulation device, a backup impulse to the ventricle when at least the ventricular delay exceeds a delay value stored in a memory of the stimulation device. The stored delay may, for example, correspond to a previously determined value indicative of selective or other His bundle capture.

Abstract: In situations in which an implantable medical device (e.g., a subcutaneous ICD) is co-implanted with a leadless pacing device (LPD), it may be important that the subcutaneous ICD knows when the LPD is delivering pacing, such as anti-tachycardia pacing (ATP). Techniques are described herein for detecting, with the ICD and based on the sensed electrical signal, pacing pulses and adjusting operation to account for the detected pulses, e.g., blanking the sensed electrical signal or modifying a tachyarrhythmia detection algorithm. In one example, the ICD includes a first pace pulse detector configured to obtain a sensed electrical signal and analyze the sensed electrical signal to detect a first type of pulses having a first set of characteristics and a second pace pulse detector configured to obtain the sensed electrical signal and analyze the sensed electrical signal to detect a second type of pulses having a second set of characteristics.

Abstract: An implantable system, and methodology, for improving a heart's hemodynamic performance featuring (a) bimodal electrodes placeable on the diaphragm, out of contact with the heart, possessing one mode for sensing cardiac electrical activity, and another for applying cardiac-cycle-synchronized, asymptomatic electrical stimulation to the diaphragm to trigger biphasic, diaphragmatic motion, (b) an accelerometer adjacent the electrodes for sensing both heart sounds, and stimulation-induced diaphragmatic motion, and (c) circuit structure, connected both to the electrodes and the accelerometer, operable, in predetermined timed relationships to the presences of valid V-events noted in one of sensed electrical and sensed mechanical, cardiac activity, to deliver diaphragmatic stimulation.

Abstract: The infrared denaturing device of the present invention is provided with: an infrared lamp which emits infrared light; a light guide which guides the infrared light; and a light projecting body which radiates the infrared light guided from the light guide onto an object to be denatured. The light projecting body is provided with: a reflecting surface which reflects the infrared light; and a radiating surface which radiates the infrared light reflected by the reflecting surface onto an object to be irradiated. Further, there is also provided a denaturing detection sensor which detects denaturing, by means of the infrared light, of a region being denatured.

Abstract: Systems and methods for controlling brain activity are provided. In some aspects, a method for controlling a synchrony in brain activity of a subject is provided. The method includes positioning stimulators to stimulate a first region and a second region of a subject's brain, and selecting a pulsed stimulation sequence comprising a first stimulation to the first region and a second stimulation to the second region, wherein the stimulations are timed to be substantially concurrent and separated by a phase lag. The method also includes delivering the pulsed stimulation sequence, using the stimulators, to control a synchrony between the first region and the second region at a predetermined frequency.

Abstract: A method of detecting abnormalities in an ECG signals, comprising receiving an ECG signal, extracting at least one ECG beat the ECG signal; providing the at least one ECG beat to a neural network. Within the neural network, performing at least two layers of convolution operations, and for a beat of the ECG signal, determining a confidence map for the location of each of the P, Q, R, S and T points, determining, from the respective confidence maps the position or absence of points, the points comprising each of the P, Q, R, S and T points; and reporting the positions and/or absence of the points.

Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.

Abstract: Disclosed are devices, systems and methods for monitoring electrophysiological function from anatomical structures, including gastric slow-waves in high resolution electrogastrograms.

Abstract: Systems and methods for evaluating electrograms are described. An example method of evaluating an electrogram such as an atrial and/or ventricular electrogram containing a plurality of data samples each having a voltage includes selecting an activity interval for the electrogram, calculating an energy level for each window of a plurality of windows of the electrogram based on the voltages of the data samples in each window, assigning the calculated energy levels to a plurality of bins, and calculating an index based at least in part on a number of energy levels assigned to a particular bin of the plurality of bins.

Abstract: Disclosed herein is a head-mounted apparatus, including: an optical sensor having a contact face for contacting with the head of a user; a supporting unit disposed around the optical sensor and configured to contact with the head of the user; and a sensor supporting mechanism configured to support the optical sensor so as to permit a movement of the optical sensor in a contact direction that is a direction perpendicular to the contact face.

Abstract: A meal detection method executed by a processor of a computer, the meal detection method includes acquiring first sensing data from a first sensor configured to detect a motion of an arm of a target person; acquiring second sensing data from a second sensor configured to detect a heart rate of the target person; setting a motion section in which a specific motion by the arm of the target person is executed at least twice or more based on the first sensing data; and determining whether a meal is performed in a section including at least a portion of the motion section, based on the second sensing data corresponding to the motion section and learning information corresponding to a unit motion of the specific motion at a time of the meal.

Abstract: A user equipment that includes a touchscreen, and at least one processor configured to generate first timestamp data based upon detection of a first touch event on the touchscreen, and second timestamp data based upon detection of a second touch event on the touchscreen, for calculation by a medical device system of a patient-specific functional status parameter associated with a Sit-To-Stand performance test over a time segment inclusively bounded by a first time defined by the first timestamp data and a second time defined by the second timestamp data.

Abstract: A system and method for selecting leadwire stimulation parameters includes a processor iteratively performing, for each of a plurality of values for a particular stimulation parameter, each value corresponding to a respective current field: (a) shifting the current field longitudinally and/or rotationally to a respective plurality of locations about the leadwire; and (b) for each of the respective plurality of locations, obtaining clinical effect information regarding a respective stimulation of the patient tissue produced by the respective current field at the respective location; and displaying a graph plotting the clinical effect information against values for the particular stimulation parameter and locations about the leadwire, and/or based on the obtained clinical effect information, identifying an optimal combination of a selected value for the particular stimulation parameter and selected location about the leadwire at which to perform a stimulation using the selected value.

Abstract: A method of preventing infection resulting from implanting a medical device. The method includes installing a polymer device at least substantially within a subcutaneous pocket formed to contain a housing of the medical device, and installing the medical device housing in the subcutaneous pocket. The polymer device includes a bioresorbable polymer structure and an antimicrobial agent configured to elute from the polymer structure. The polymer device covers less than about 20% of the surface area of the medical device housing.

Abstract: A method and system for determining a source of a cardiac rhythm disorder includes collecting cardiac signals at a plurality of locations during a cardiac arrhythmia and identifying activation times within the cardiac signals. After computing the time-dependent phase of each region of tissue, a level of phase synchrony is determined between each pair of locations to assign a synchronization number for each pair of locations. Using the synchronization number, a spatial synchrony map is generated to identify one or more asynchronous tissue regions surrounded by regions of synchrony in the patient's heart.

Abstract: A drowsiness detecting device includes a feature extractor, a detecting rule storage unit, a normalizer, and a drowsiness detector. The feature extractor extracts a feature value on heartbeats of a user based on intervals between the heartbeats. The detecting rule storage unit retains a detecting rule for drowsiness detecting. The normalizer updates a normalization coefficient. The drowsiness detector detects drowsiness of the user based on the feature value, the detecting rule, and the normalization coefficient. The normalizer updates the normalization coefficient based on the feature value when the drowsiness detector does not detect the drowsiness of the user.

Abstract: A delivery device for delivering an implantable leadless pacing device may include a catheter shaft a distal holding section for receiving the implantable leadless pacing device. In some cases, the delivery device may include a flow-sensing device to determine a pressure or flow-rate of a fluid within the distal holding section. Also included may be a handle assembly and a deployment mechanism to deploy the implantable leadless pacing device.

Abstract: A system for controlled sympathectomy procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed. Systems and methods for accessing target tissues as part of a neuromodulation procedure from within a lumen are disclosed.

Abstract: Self-directed health screening systems and methods utilizing user navigation and device integration, health analyzing algorithms, and/or self-learning techniques for the detection, quantifying, prevention, and management of health risks and discoverable health conditions. Implementations herein may include components or involve aspects associated with information collection, information processing, display/provision/rendering of professional advice, and/or processing of various associated data and information via network(s). Implementations herein provide for innovatively configured, easily upgradable, efficient, portable, scalable, easy-to-use, usage-encouraging, and/or effective implementations for screening, predicting points of inflection of pending health issues, preventing and/or managing users' health, provided via various and multiple embodiments having numerous advantages over other known techniques.