Abstract: Systems and methods for applying a pulsed electromagnetic fields. A system for applying a pulsed electromagnetic field (PEMF) to a cell, comprising: a sensor for obtaining a characteristic of the cell; a memory module having stored therein a plurality of characteristics and PEMF efficacy window data, each characteristic having its corresponding PEMF efficacy window data; a pulse generator coupled to a set of PEMF coils and configured to generate an output of electrical pulses to drive the set of PEMF coils; and a controller in communication with the sensor, the memory module and the pulse generator, wherein the controller is configured to: retrieve, from the memory module, the PEMF efficacy window data that corresponds to the characteristic of the cell obtained by the sensor; and control the output of the pulse generator based on the retrieved PEMF efficacy window data such that the set of PEMF coils apply a PEMF in accordance with the PEMF efficacy window data.

Abstract: Present embodiments are directed to measuring and calculating parameters to control and monitor a power transfer in an implanted medical device. The medical device may be implanted in a subject and typically includes an artificial heart or ventricle assist device. The system measures parameters and uses the parameters to calculate a coupling coefficient for coils that transfer power between an external primary and an implanted secondary. The system uses the calculated coupling coefficient to estimate heat flux being generated in the system. Based on the level heat flux detected, the system may issue alerts to warn the subject or control actions to mitigate the effects of the heat flux.

Abstract: A vestibular stimulation array is disclosed having one or more separate electrode arrays each operatively adapted for implantation in a semicircular canal of the vestibular system, wherein each separate electrode array is dimensioned and constructed so that residual vestibular function is preserved. In particular, the electrode arrays are dimensioned such that the membranous labyrinth is not substantially compressed. Furthermore, the electrode array has a stop portion to limit insertion of the electrode array into the semi-circular canal and is still enough to avoid damage to the anatomical structures.

Abstract: An implantable medical lead includes (i) a proximal end portion including a contact and having a proximal end; and (ii) a distal end portion including an electrode and having a distal end. The electrode is electrically coupled to the contact. The distal end portion is generally flat and sufficiently stiff to be pushed through subcutaneous tissue.

Abstract: Systems and methods are provided for an electrocardiograph system. A set of electrodes is configured to detect a voltage differences between various pairs of locations on a body of a patient. A display is configured to visually represent digital signals derived from the plurality of detected voltage differences. A display interface is configured to format the digital signals for the display, such that the leads are grouped and displayed as a sequence of proper subsets or groups of the plurality of detected voltage differences. Each proper subset or lead group represents a specific anatomical structure of a heart of the patient.

Abstract: Embodiments of the present disclosure can provide systems, methods, and computer-readable medium for tracking the heartrate of a user using different techniques associated with different contexts. For example, motion of a user wearing a wearable device can be tracked using at least first sensors of the one or more sensors. The physical state of the user can also be tracked using at least second sensors of the one or more sensors. In some cases it can be determines whether an application of the wearable device has been launched. Additionally, an activity category of the user can be determined based at least in part on the motion of the user, the physical state of the user, and/or whether the application has been launched. Heartrate data of the user can be collected, and the heartrate data can be categorized based at least in part on the determined category.

Abstract: Devices and methods to deliver microcurrent stimulation therapy to the human body, when connected to a micro-stimulation current-generating apparatus. The method of applying microcurrent stimulation therapy to key points around the eye for treatment of problems such as macular degeneration, retinitis pigmentosa, glaucoma, optic neuritis and other eye-related or nerve-related conditions, as well as other diseases, such as Bell's Palsy, requiring localized stimulation to the eyes and/or on other body parts.

Abstract: This disclosure relates to integrated channel integrity detection and to reconstruction of electrophysiological signals. An example system includes a plurality of input channels configured to receive respective electrical signals from a set of electrodes. An amplifier stage includes a plurality of differential amplifiers, each of the differential amplifiers being configured to provide an amplifier output signal based on a difference between a respective pair of the electrical signals. Channel detection logic is configured to provide channel data indicating an acceptability of each of the plurality of input channels based on an analysis of a common mode rejection of the amplifier output signals.

Abstract: A sensing device for detecting an artificially induced neuromuscular response within a limb of a subject includes a carrier material and a plurality of mechanical sensors. The carrier material is operative to be secured around a portion of the limb, and each of the plurality of mechanical sensors are coupled with the carrier material. Each mechanical sensor is positioned on the carrier material such that it is operative to monitor a mechanical response of a different muscle group of the limb. Each mechanical sensor then generates a respective mechanomyography output signal corresponding to the monitored mechanical response of its adjacent muscle group. These signals may then be communicated outbound from the device via communication circuitry provided on the device.

Abstract: A cochlear implant electrode includes an implantable electrode array made of resilient material with a center longitudinal axis and an outer surface. Electrode contacts are distributed on the outer surface of the electrode array along the longitudinal axis for applying electrical stimulation signals to adjacent neural tissue. At least one biocompatible hydrogel layer is fixed to the electrode array solely by mechanical connection and adapted to swell from contact with perilymph fluid within a cochlea without separating away from the outer surface of the electrode array.

Abstract: A hearing prosthesis arrangement is described for a hearing assisted patient. A microphone senses an acoustic environment around the hearing assisted patient and generates a corresponding microphone output signal. An audio signal processor processes the microphone output signal and produces a corresponding prosthesis stimulation signal to the patient for audio perception. The audio signal processor includes a dereverberation process that measures a dedicated reverberation reference signal produced in the acoustic environment to determine reverberation characteristics of the acoustic environment, and reduces reverberation effects in the hearing prosthesis stimulation signal based on the reverberation characteristics.

Abstract: Presented herein are implantable medical devices that comprise an implantable portion having a resonant tank circuit that is used to receive signals from one or more external devices. The resonant tank circuit is configured to operate at first and second resonant frequencies, where the first resonant frequency is optimized to exchange data with, and potentially receive operating power from, an external device, while the second resonant frequency is optimized to receive charging power. In certain embodiments, upon initiating operation of the implantable portion with at least one external device, the implantable portion is configured to force tune the resonant tank circuit to the first resonant frequency. That is, when the resonant tank circuit first begins receiving signals from an external device, the signals received at the resonant tank circuit are used to initially tune the resonant tank circuit to the first resonant frequency.

Abstract: A direct current delivery device includes a direct current source or a device for connecting to a direct current source, and a first electrode and a second electrode for connecting to the direct current source, wherein the first electrode is configured as a plurality of needles and the second electrode is configured as a planar electrode, as a needle or a plurality of needles directly connected to one another in an electrically conductive manner. The direct current delivery device includes one or more devices configured to maintain the current intensity constant during the individual delivery of direct current through the needles of the first electrode.

Abstract: Methods and devices adapted for cardiac signal analysis. A method or device has accessible to it more than one approach to cardiac cycle rate analysis and is adapted to monitor sensing signal quality. In response to an apparent reduction in signal quality or other trigger, the method or device checks whether an arrhythmia or an actual drop in signal quality is occurring prior to modifying sensing configurations or parameters.

Abstract: A magnet arrangement for an implantable medical device is described. An implantable coil case contains a communications coil and is made of biocompatible resilient material with a top lateral surface. A magnet receptacle is located within the coil case and has a receptacle opening in the top lateral surface. An implant magnet fits within the magnet receptacle and has opposing end surfaces, and a center body region located between the end surfaces. An elastic opening clamp is located radially around the receptacle opening and is configured to normally be closed around the receptacle opening to maintain the implant magnet within the magnet receptacle. The elastic opening clamp also is configured to cooperate with a surgical handling tool to expand the receptacle opening to permit the implant magnet to be removed from the magnet receptacle through the receptacle opening without needing to move the coil case.

Abstract: Methods and systems are provided for determination and mapping of vector fields which characterize wavefront motion through space and time. The inventive methods and systems utilize data from spatially-distributed locations and maps wavefront vector flow fields in an entirely automated manner. These maps can be used to characterize the activation as planar, centrifugal, or rotational. Further, the strength of rotation or divergence is determined from these fields and can be used to select spatial points of significantly increased rotational or focal activity. As applied to electrophysiological data recorded during heart rhythm disorders in patients, the inventive method provides a means of visual interpretation of complex activation maps. The information related to the strength and location of rotation and centrifugal activity during episodes of arrhythmia can guide therapies designed to treat such disorders.

Abstract: An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

Abstract: An external control device for indicating whether a stimulation parameter set for use in a neurostimulator is available on a remote control in communication with the external control device is provided. The device includes a user interface configured for displaying the stimulation parameter set and an indicator that indicates whether the stimulation parameter set is available to the patient from the remote control. The device also includes control circuitry configured for, in response to input from the user (e.g., actuating the indicator), selectively turning the indicator on or off. The indicator may be an icon, and the icon may be a graphical depiction of a remote control. The user interface may be further configured for receiving additional input from the user, and the control circuitry may be further configured for, in response to the additional input from the user, programming the remote control with the stimulation parameter set.

Abstract: Various aspects of the present subject matter provide an implantable medical device. In various embodiments, the device comprises a pulse generator, a first monitor and a controller. The pulse generator is adapted to generate a neural stimulation signal for a neural stimulation therapy. The neural stimulation signal has at least one adjustable parameter. The first monitor is adapted to detect an undesired effect. In some embodiments, the undesired effect is myocardial infarction. The controller is adapted to respond to the first monitor and automatically adjust the at least one adjustable parameter of the neural stimulation signal to avoid the undesired effect of the neural stimulation therapy. Other aspects are provided herein.

Abstract: An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator wirelessly receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and wirelessly outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes wirelessly connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto.