Patents Examined by Mina Haghighatian
  • EL 000614 strain having nematicidal activity against root knot nematode and uses thereof
    Patent number: 10980242
    Abstract: Xylaria grammica EL 000614 strain has a nematicidal activity against root knot nematode. A method for controlling root knot nematode includes treating a crop, a crop seed, or a field for cultivation with a nematicidal microorganism formulation. The method has very little possibility of having a problem related to environmental contamination, and exhibits a high mortality and activity of inhibiting egg hatching for sweet potato root knot nematode (M. incognita). It is expected that the strain can be very advantageously used as an innovative biological control agent which enables prevention of problems associated with environmental contamination.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: April 20, 2021
    Assignees: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, NATIONAL INSTITUTE OF BIOLOGICAL RESOURCES
    Inventors: Jin-Cheol Kim, Tae Yoon Kim, Ja Yeong Jang, Nan Hee Yu, Won-Jae Chi, Chang Hwan Bae, Joo Hong Yeo
  • High-strength testosterone undecanoate compositions
    Patent number: 10973833
    Abstract: The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The capsule includes a capsule shell and a capsule fill. The capsule fill can include a solubilizer and about 14 wt % to about 35 wt % testosterone undecanoate based on the total capsule fill. The oral dosage capsule is such that when a single oral administration to a male subject of one or more capsules with a total testosterone undecanoate daily dose of about 350 mg to about 650 mg it provides a ratio of serum testosterone Cmax to serum testosterone Cave of about 2.7 or less. In yet another embodiment, a method for providing a serum concentration of testosterone within a target serum testosterone concentration Cave range for a male subject is provided.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: April 13, 2021
    Assignee: Lipocine Inc.
    Inventors: Chandrashekar Giliyar, Basawaraj Chickmath, Nachiappan Chidambaram, Mahesh V. Patel, Srinivansan Venkateshwaran
  • Fibrin sealant products
    Patent number: 10953128
    Abstract: A fibrin sealant product having a plurality of layers that each includes a dextran support and at least one fibrin sealant agent. The at least one fibrin sealant agent is placed on the dextran support to form each of the layers. The plurality of layers is placed in a stacked configuration to form the fibrin sealant product. A plurality of crimps is dispersed over a surface of the fibrin sealant product to retain the plurality of layers in a position with respect to each other.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: March 23, 2021
    Assignee: St. Teresa Medical, Inc.
    Inventors: Rudy Padua, Philip Messina
  • Compositions and methods for ophthalmic and/or other applications
    Patent number: 10945948
    Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: March 16, 2021
    Assignee: The Johns Hopkins University
    Inventors: Alexey Popov, Elizabeth M. Enlow, Hongming Chen, James Bourassa
  • Combination dosage form of a mu opioid receptor antagonist and an opioid agent
    Patent number: 10946009
    Abstract: The invention provides a solid composition of the peripheral mu opioid antagonist axelopran and a combination dosage form of the mu opioid antagonist axelopran sulfate in an immediate release form and an opioid analgesic agent which may be in an extended release, sustained release, modified release, or controlled release form and methods of preparing such a combination dosage form.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: March 16, 2021
    Assignee: Theravance Biopharma R&D IP, LLC
    Inventors: Shaoling Li, Manshiu Leung, Hao Zhang, Venkat R. Thalladi, Yun Mo
  • Compositions and methods for ophthalmic and/or other applications
    Patent number: 10940108
    Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: March 9, 2021
    Assignee: The Johns Hopkins University
    Inventors: Alexey Popov, Elizabeth M. Enlow, Hongming Chen, James Bourassa
  • Solid agrochemical compositions
    Patent number: 10925280
    Abstract: The present invention provides storage stable non-hygroscopic granular compositions comprising agrochemical active ingredients and at least two surfactants selected from an amine, an alkoxylated fatty alcohol and an alkylated vegetable oils.
    Type: Grant
    Filed: July 30, 2016
    Date of Patent: February 23, 2021
    Assignee: UPL LIMITED
    Inventors: Paresh Vithaldas Talati, Jaidev Rajnikant Shroff, Vikram Rajnikant Shroff, Ekanath Bhoge Satish
  • Process for preparing a dermatological composition comprising oleosomes
    Patent number: 10925822
    Abstract: A method is described for producing an oil-in-water emulsion including oil globules, the mean diameter of which is less than 500 nm and each of which is provided with a lamellar liquid crystal coating, and which are dispersed in an aqueous phase. Each oil globule is individually coated with a unilamellar or oligolamellar layer obtained from at least one lipophilic surfactant, at least one hydrophilic surfactant, and at least one separate anionic surfactant, characterized in that the number of steps in the method is no greater than 5, in that the temperatures used during the different steps are no higher than 75° C., and in that the method requires neither the use of a high-pressure homogenizer nor any pre-emulsification step.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: February 23, 2021
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventor: Amel Safia Djedour
  • Solid non-aqueous gel air odorizer
    Patent number: 10918756
    Abstract: A solid non-aqueous gel air odorizer is provided, including: a poly(propylene oxide); an ethyl cellulose polymer; a C1-5 alkyl monoester of a C8-22 fatty acid; and a fragrance; wherein the solid non-aqueous gel air odorizer contains <1.5 wt % water.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: February 16, 2021
    Assignee: Dow Global technologies LLC
    Inventor: Severine Ferrieux
  • Agrochemical combination
    Patent number: 10912295
    Abstract: The present invention relates to an agrochemical combination of (i) linolenic acid, a linolenic acid derivative, a linolenic acid breakdown component, or an ester thereof; and (ii) inositol, an inositol derivative or an inositol breakdown component. The invention also relates to agrochemical compositions comprising the same and the use such a combination for improving plant physiology.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: February 9, 2021
    Assignee: Crop Intellect Ltd.
    Inventor: Apostolos Papadopoulos
  • Extended release multiparticulates of ranolazine
    Patent number: 10898444
    Abstract: The present invention relates to an extended release multiparticulate composition comprising a plurality of discrete units, each discrete unit comprising ranolazine or a pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients. The said multiparticulate composition is sprinkled onto soft foods or liquids for oral administration. Further, the multiparticulate composition is bioequivalent to the marketed extended release tablet. It further relates to a process of preparation of said multiparticulate composition and method of treatment of patients suffering from angina by administering said composition.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: January 26, 2021
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Harinder Singh, Shavej Ahmad, Romi B. Singh
  • High-strength testosterone undecanoate compositions
    Patent number: 10881671
    Abstract: The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The capsule includes a capsule shell and a capsule fill. The capsule fill can include a solubilizer and about 14 wt % to about 35 wt % testosterone undecanoate based on the total capsule fill. The oral dosage capsule is such that when a single oral administration to a male subject of one or more capsules with a total testosterone undecanoate daily dose of about 350 mg to about 650 mg it provides a ratio of serum testosterone Cmax to serum testosterone Cave of about 2.7 or less. In yet another embodiment, a method for providing a serum concentration of testosterone within a target serum testosterone concentration Cave range for a male subject is provided.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: January 5, 2021
    Inventors: Chandrashekar Giliyar, Basawaraj Chickmath, Nachiappan Chidambaram, Mahesh V. Patel, Srinivansan Venkateshwaran
  • Pesticidally active pryazole derivatives
    Patent number: 10874104
    Abstract: Compounds of formula (I), as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control pests such as insect, acarine, mollusc and nematode pests.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: December 29, 2020
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: André Jeanguenat, Thomas Pitterna, Myriem El Qacemi, André Stoller, Régis Jean Georges Mondiere, Aurelien Bigot, Andrew Edmunds, Denis Gribkov
  • Coniothyrium minitans for use against moss growth
    Patent number: 10869483
    Abstract: The invention relates to the use of Coniothyrium minitans for controlling moss growth and to a method of controlling moss growth, comprising applying Coniothyrium minitans to an area to be kept free from mosses.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: December 22, 2020
    Assignee: Bayer CropScience Aktiengesellschaft
    Inventor: Sandra Noga
  • Transdermal delivery of pharmaceutical agents
    Patent number: 10869842
    Abstract: A method of administering a pharmaceutical agent to the circulatory system through the skin of a mammal may include the steps of loading a pharmaceutical agent in a transdermal patch, applying the transdermal patch to the skin of the mammal and releasing the pharmaceutical agent into the circulatory system at a rate of at least 0.001 micrograms per hour up to 50.0 micrograms per hour per kilogram of bodyweight of the mammal. The drug delivery system may comprise a transdermal patch loaded with the pharmaceutical agent. The patch may include a porous membrane and an outer impermeable cover defining a cavity therebetween. A plurality of drug delivery layers may be disposed between the porous membrane and the impermeable cover. A lipophilic/hydrophilic suspension may be disposed between the drug delivery layers.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: December 22, 2020
    Inventor: David P Summers
  • Botulinum toxin and colloidal silver particles
    Patent number: 10864231
    Abstract: Botulinum toxin is combined with colloidal silver particles to provide improved compositions for use in medical and cosmetic treatments.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: December 15, 2020
    Assignees: American Silver, LLC, Dr. Andrew Willoughby Inc.
    Inventors: Andrew J. M. Willoughby, Keith William Moeller
  • Compositions and methods for ophthalmic and/or other applications
    Patent number: 10864219
    Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: December 15, 2020
    Assignee: The Johns Hopkins University
    Inventors: Alexey Popov, Elizabeth M. Enlow, Hongming Chen, James Bourassa
  • Tobramycin magnesium stearate microparticles for inhalation, compositions thereof, and methods of making and using the same
    Patent number: 10857169
    Abstract: Powder formulations for inhalation which comprise microparticles containing an antibiotic and magnesium stearate are useful for the treatment of bacterial infections associated with certain pulmonary diseases.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: December 8, 2020
    Assignee: CHIESI FARMACEUTICI S.p.A.
    Inventors: David Morton, Qi Zhou, Rossella Musa
  • Gastroretentive dosage forms for sustained drug delivery
    Patent number: 10857098
    Abstract: The present disclosure is directed to floating gastroretentive dosage forms with prolonged gastric residence time. The disclosure also provides rapidly expanding sustained release or combined immediate release and sustained release formulations comprising drugs that require targeted release in the proximal gastrointestinal tract for maximum therapeutic benefit. The rapidly expanding floating gastroretentive dosage forms comprise a permeable elastic membrane providing desired characteristics for drug release and mechanical strength to maintain tablet integrity.
    Type: Grant
    Filed: May 6, 2020
    Date of Patent: December 8, 2020
    Assignee: KASHIV SPECIALTY PHARMACEUTICALS, LLC
    Inventors: Kanji Meghpara, Jaydeep Vaghashiya, Navnit H. Shah, Dipen Desai, Wantanee Phuapradit, Harpreet Kaur Sandhu, Siva Ram Kiran Vaka, Namdev B. Shelke, Ashish Chatterji
  • Compositions and methods for ophthalmic and/or other applications
    Patent number: 10857096
    Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: December 8, 2020
    Assignee: The Johns Hopkins University
    Inventors: Alexey Popov, Elizabeth M. Enlow, Hongming Chen, James Bourassa