Abstract: Biocompatible anion exchange materials are provided comprising a support having a quaternary amine moiety and a polyethylene oxide (PEO) moiety having between about 10 and about 200 repeating units covalently bonded thereto, such that said quaternary amine and polyethylene oxide moieties are substantially homogeneously distributed on said support. These anion exchange materials are useful for removing negatively charged species such as heparin from blood and other body fluids without significant removal of platelets. Methods of making and using these materials are also provided.

Abstract: The present invention relates to compositions and their methods of manufacture and use which are effective for delivering a homogeneous distribution of a boron containing active ingredient to a tree or tree derived substrate for the purpose of preventing or eradicating an infestation and/or for imparting flame retardency thereto.

Abstract: The invention relates to the use of, and methods to obtain, ion exchanger complexes with psychotropic drugs for reducing toxic side effects and lethality when overdosing the drug. The invention includes methods and compositions for modifying the total amount of drug released from the complex in the gastro-intestinal tract by adding a substance which affects the ion exchange process. The additional substance may be a salt which generates an ion with higher or similar affinity to the ion exchanger when compared to the drug. The additional substance may be a counter ion in an additional complex with an ion exchanger.

Abstract: A deodorizing material for breeding or keeping animals and a process for producing the same are described. The material comprises a formed article of a pulp and/or polyolefin base material, wherein said formed article has a cation exchange group. The material is produced by graft polymerization of a reactive monomer having a cation exchange group to a formed article of a pulp and/or polyolefin base material. The material efficiently adsorbs bad smells of animals' excretions through chemical bonding.

Abstract: A moldable biodegradable surgical material is made of a bioabsorbable polymer derived from hydroxyacids, tactones, carbonates, etheresters, anhydrides, orthoesters and copolymers, terpolymers and/or blends thereof, the polymer blended with at least one surface active agent selected from the group consisting of fatty acid ester and poly(oxypropylene)/poly(oxyethylene) block copolymer. In one embodiment, a leaching agent is blended with the above-mentioned surgical material. Methods of making moldable biodegradable surgical material are provided. The surgical material may be used as a moldable bone wax in connection with repair of wounds and is an adaptable aid for any appropriate surgical use, e.g., hemostat, anchor, patch etc.

Abstract: The present invention is an injectable medical composition useful for replacing natural lubricating fluids in the body of humans or animals. The method and composition can be used for the treatment of joints and other parts of the body wherein natural lubrication between surfaces is deficient or where additional lubrication is required. The composition comprises a hydrophilic polymer suspended in a hydrophobic carrier so that the suspension is easily injectable into the desired body part. After injection, the carrier diffuses away from the polymer and is replaced by aqueous body fluids thereby causing the polymer to absorb or adsorb water forming a viscous, lubricating fluid.

Abstract: A stable solid controlled release formulation having a coating derived from an aqueous dispersion of a hydrophobic acrylic polymer includes a substrate including an active agent selected from the group consisting of a systemically active therapeutic agent, a locally active therapeutic agent, a disinfecting and sanitizing agent, a cleansing agent, a fragrance agent and a fertilizing agent, overcoated with an aqueous dispersion of the plasticized water-insoluble acrylic polymer. The formulation provides a stable dissolution of the active agent which is unchanged after exposure to accelerated storage conditions.

Abstract: Tabletized ionene polymers, methods for their preparation and their use in water treatment is described. The tablet contains about 5 to about 60 percent by weight of an ionene polymer, about 40 to about 95 percent by weight of a salt carrier matrix, 0 to about 10 percent by weight of a disintegration rate regulator, and 0 to about 10 percent by weight of an anticaking agent. The tablets may be made by mixing an aqueous solution of an ionene polymer with a carrier matrix to form a moist mass, drying the moist mass to form granules, reducing the granule size to form a powder, and compressing the powder into a tablet. The tablets are useful in a wide variety of water treatment applications. Accordingly, the specification describes a method for controlling the growth of microorganisms in an aqueous system. Using the method, one treats an aqueous system with an ionene polymer in an amount effective to control the growth of at least one microorganism. The ionene polymer is contained in a tablet of the invention.

Abstract: Disclosed are a method and composition for intralesional therapy of solid cancer tumors, and especially brain tumors, comprising, delivering a compound of a 1,2,4-benzotriazine oxide contained in a biodegradable, slow release polymer and subjecting the cancer tumors to irradiation therapy.

Abstract: The product invention entitled as water based UV curable human nail coating is the result of years of experience, research and testing. The formula is as follows: aliphatic waterborne urethane containing 40% solids in water with N.N-Diethylethanamine, acrylated urethane containing 50% polymer of alkyl carbomonocycle diisocyanate with alkanepolyol polyacrylates and 50% acrylated polyol, isopropanol, propylene glycol methyl ether acetate, 2-hydroxy-2-methyl-1-phenyl-1-propanone, hydrolyzed keratin @ 125,000 molecular weight 13% solids in water with 2% propylene glycol, protein hydrolyzate from milk. These ingredients are placed in a plastic mixing container in the given order then thoroughly mixed for 10 minutes or until all visible lumps and droplets are no longer visible.

Abstract: The present invention relates to stabilized topical pharmaceutical preparations. More specifically the present invention relates to a stabilized topical pharmaceutical preparation, based on the solubilization of a eutectic mixture of local anesthetic agents, in base form, which when combined in the presence of a surfactant and water produce a single phase hydrated polymer to be used in obtaining topical anesthesia and also relates to a stabilized antimicrobial topical pharmaceutical preparation.

Abstract: A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to which is bound a nitric oxide-releasing N.sub.2 O.sub.2.sup.- functional group; pharmaceutical compositions comprising the polymeric composition; and methods of treating biological disorders in which dosage with nitric oxide is therapeutic.

Abstract: The present invention relates to hair care compositions which contain a polymer which is prepared from N-vinyl formamide (NVF) monomer and the use of those hair care compositions to treat hair. The polymer may be a homopolymer of NVF or an interpolymer of NVF and at least one vinyl monomer. The polymer is present in amounts effective to provide the hair care compositions with hair fixative properties and/or hair conditioning properties.

Abstract: AIDS therapeutic agents are provided which are less toxic, have a strong anti-AIDS virus activity and comprise as an effective ingredient a dehydrogenation polymer of a cinnamic acid derivative having a phenyl group substituted with at least one hydroxyl group or a pharmaceutically acceptable salt thereof.

Abstract: An anhydrous dental bleaching gel composition is provided which has improved package stability, improved rheology and reduced sensitivity during use. An illustrative anhydrous dental bleaching gel composition embodying these features comprises propylene glycol, polyethylene glycol, glycerin in an amount not exceeding about 10 wt. %, neutralized carboxypolymethylene, hydroxypropylcellulose, and carbamide peroxide.

Abstract: To stabilize the active ingredients, a caffeine is incorporated into a solid pharmaceutical preparation comprising a dextromethorphan and a phenylpropanolamine. The pharmaceutical preparation may further comprise ibuprofen. The active ingredients may be further stabilized, in combination with the incorporation of the caffeine, by grouping and incorporating separately each or suitably combined plural of the active ingredients into different groups or by minimizing the amount of any reducing sugar such as lactose. The solid pharmaceutical preparation is practically valuable since decomposition of each active ingredient with the lapse of time is remarkably suppressed and the active ingredients are stabilized for a longer period of time.

Abstract: The present invention relates to an improved method for the cytoplasmic delivery of oligonucleotides using cationic copolymers based on vinyl alcohol with low levels of vinyl amine (PVAVAMs). Improved compositions for use in such method are also provided.

Abstract: A method of faciltating the obtaining of a mucus sample from at least one lung of a subject comprises administering a physiologically acceptable salt to at least one lung of the subject in an amount effective to hydrate lung mucus secretions therein, and concurrently administering to said at least one lung of the subject, in an amount effective to hydrate lung mucous secretions therein, uridine triphosphate, an active analog thereof, or a pharmaceutically acceptable salt of either thereof. Pharmaceutical compositions useful for carrying out the method comprise, in combination, a physiologically acceptable salt, and uridine triphosphate, an active analog thereof, or a pharmaceutically acceptable salt of either thereof. The composition may be a liquid composition or a dry powder composition.

Abstract: Ferric oxyhydroxide-dextran compositions for treating iron deficiency having ellipsoidal particles with a preferred molecular weight range of about 250,000 to 300,000 daltons.

Abstract: The present invention discloses permselective membranes comprising at least one layer formed from an arylenedialkylidene polymer at least a portion of which is sulfonated, said arylenedialkylidene polymer comprising recurring monomeric units as shown by the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are alkyl having one to four carbon atoms; wherein A and B are different;A is selected from the group consisting of ##STR2## wherein R.sub.x is hydrogen or an alkyl having 1 to 4 carbon atoms, R.sub.5 is alkylidene of 1-4 carbon atoms or oxyalkylene of 1-4 carbon atoms;B is derived from the group consisting of benzene, naphthalene, thiophene, and aromatic compounds of the formula ##STR3## wherein R.sub.6 is selected from the group consisting of alkylidene of 1-4 carbon atoms, oxyalkylene of 1-4 carbon atoms, --O--, --S--; R.sub.7 and R.sub.