Abstract: New acylated urea compounds of the formula ##EQU1## IN WHICH R.sup.1 is alkyl, haloalkyl or optionally substituted aryl,R.sup.2 and R.sup.3, which may be the same or different, are each alkyl or alkenyl, andAz is a 1,3,4-thiadiazole radical which is linked in the 2-position and is optionally substituted in the 5-position;Exhibit excellent herbicidal activity and can be used as selective or total herbicides.

Abstract: A process for the preparation of 2H-3-isoquinolones having the formula ##SPC1##Wherein R.sub.1 and R.sub.2 are each hydrogen, halogen, lower alkyl, lower alkoxy, aryl, haloaryl, alkylaryl or alkoxyaryl; R.sub.3 and R.sub.4 are each hydrogen, lower alkyl, lower alkoxyalkyl, lower alkenyl, lower alkynyl, cycloalkyl, aryl, aralkyl, or halo-aralkyl, which comprises cyclizing an N-formyl-2-phenyl-acetamide of the formula ##SPC2##Wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have the same meaning as above, with a cyclodehydration agent. Said 2H-3-isoquinolones are useful as starting materials e.g. in the synthesis of 1,4-dihydro-1,4-etheno-isoquinolin-3(2H)-ones which are valuable chemotherapeutic agents in the treatment of disorders of the central nervous system, such as troubles of wakefulness, disorders of equilibrium and vertigo.

Abstract: 6-Acylamino-penam-3-carboxylic acids and 7-acylamino-3-cephem-4-carboxylic acids in which the acyl group has the formula ##EQU1## in which R.sub.1 is hydrogen, R.sub.2 is optionally substituted phenyl, thienyl or furyl, or R.sub.1 and R.sub.2 together are optionally substituted cycloalkyl, and B is a radical which is bonded via a sulphur atom or is bonded to oxygen or sulphur with the interposition of an optionally substituted CH.sub.2 -group.

Abstract: 2-Alkyl-7,8-cyclopentano[h]-1,2,3,4-tetrahydroisoquinolines of the formula ##SPC1##Wherein R is an aryl-lower alkyl amino group, an aryl-lower alkyl imino group, a diaryl-lower alkyl amino group or a diaryl-lower alkyl imino group, R.sub.1 is hydrogen or a lower alkyl group and R.sub.2 is a lower alkyl group, and acid addition salts and quaternary ammonium salts thereof, and the use of such compounds in pharmaceutical compositions to lower blood pressure in hypertensive animals.

Abstract: New compositions of matter having two ring nuclei composed of 6 carbon atoms essentially superimposed in fixed parallel planes with respect to each other and process of preparing the same.

Abstract: Perinone dyestuffs of the formuula ##SPC1##In whichR denotes alkyl, alkoxy or halogen,R.sub.1 stands for halogen, cyano, alkoxy, alkylcarbonyl, a (possibly substituted) carbonamide or carbalkoxy group, andn represents a whole number from 0 to 3, as well as their preparation and their use for the dyeing of hydrophobic fibre materials.

Abstract: 2-Amino pyrimidines bearing in the 6-position a carboxyl- or sulphonyl-esterified hydroxy or mercapto group; or salts thereof. Processes for making these compounds and compositions and methods for using same to combat pests are also disclosed.

Abstract: Thiophene derivatives of the formula: ##SPC1##Wherein R.sup.1 is H or CH.sub.3 ; R.sup.2 is CH.sub.3 or C.sub.2 H.sub.5, or R.sup.1 and R.sup.2 combinedly represent --(CH.sub.2).sub.4 --; each of R.sup.3 and R.sup.4 is H, alkyl of from 1 to 4 carbon atoms or cyclohexyl, or R.sup.3 and R.sup.4 together with the adjacent nitrogen atom form 1-pyrrolidinyl, piperidino, 4-methyl-1-piperazinyl or morpholino; X is H, halogen or OCH.sub.3 ; A is -CH= or --C(CH.sub.3)=, and B is =N-- or =CH--; or A is --C(CH.sub.2 OH)= or --N=, and B is =N--, and pharmaceutically acceptable acid addition salts thereof possess excellent pharmacological properties such as sedative, anxiolytic and anticonvulsant effects and protective effects against hypoxia or anoxia.

Abstract: 1,3-Disubstituted-3-aroylpropanes of the formula: ##EQU1## and their salts, in which Ar represents an aryl residue unsubstituted or substituted by halogen, polyhalogeno alkyl or lower alkoxy; R.sup.1 represents an hydroxy, acyloxy, carbamoyloxy, alkylcarbamoyloxy, dialkylcarbamoyloxy, aroyloxy, alkoxy, aryloxy, or cyano group or an amino group of the formula: ##EQU2## which can be the residue of a secondary amine, a tertiary amine, or of a heterocyclic amine; and ##EQU3## represents the residue of a secondary amine, a tertiary amine, or of a heterocyclic amine, have interesting properties as analgesic agents, anti-arrhythmic agents, and central nervous depressants.

Abstract: Dyes of the formula: ##SPC1##In whichR is unsubstituted or substituted alkyl or aralkyl;R.sup.1 to R.sup.6 is each hydrogen or a substituent;R.sup.7 is hydrogen or alkoxy;R.sup.8 is hydrogen or alkoxy;n is zero or 1;X.sup.- is an anion; andR.sup.1 and R.sup.8 may together be a radical: ##SPC2##Where R.sup.9 is hydrogen, alkyl or alkoxy; and at least one of the radicals R.sup.1 to R.sup.6 is arylmercapto.The dyes give bright colorations, particularly on polyesters and in resins.

Abstract: 6-(Triphenylmethylamino)-2,2-dimethyl-3-(N-[p-methoxybenzyl]carbamoyl)penam -dimethylsulfoxide complex as a useful intermediate leading to the synthesis of antibacterial 6-acylamino-2,2-dimethyl-3-(5-tetrazolyl)penams.

Abstract: The invention comprises an oil-soluble ashless detergent dispersant consisting of a reaction product obtained by reacting (a) an alkenyl dibasic acid or its anhydride (the alkenyl group having at least 40 carbon atoms) with (b) an alcohol of the hindered type and then reacting the so obtained intermediate with (c) an amine or its derivative or analogue [the sum of moles of primary and secondary amino groups of (c) not exceeding the sum of moles of the ester linkage formed by the reaction between (a) and (b)], or consisting of a borated or phosphosulfided product obtained by reacting the above reaction product with boric acid (or its anhydride) or phosphorus pentasulfide.

Abstract: The antibiotic thienamycin is active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a newly-found and hitherto undescribed species of Streptomyces on suitable fermentation media.

Abstract: A process for purifying beta-lactones, which comprises contacting a beta-lactone selected from the group consisting of alpha, alpha-dimethyl-beta-propiolactone, beta-propiolactone and a mixture of these with a solid alkaline earth metal hydroxide.

Abstract: Valuable antibacterial 8-alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acids, some of which are new compounds, are made from corresponding pyrimidines by a process involving condensation with an amino-ester, cyclization, halogenation, dehydrohalogenation, and saponification.

Abstract: Oxidative coupling of non-phenolic compounds is attained by subjecting said non-phenolic compound to oxidizing conditions in contact with an oxidant selected from the group of VOF.sub.3, MoOCl.sub.4, Pb.sub.3 O.sub.4, Tl(CF.sub.3 COO).sub.3, CrO.sub.3, MnO.sub.2, Co(OH).sub.3, Ce(SO.sub.4).sub.2, and Ce(NH.sub.4).sub.2 (NO.sub.3).sub.6.

Abstract: Agents and methods of using 4,6-(subst.)diamino-5-nitro-pyrimidines, most of which are new, which possess plant growth inhibiting, in particular herbicidal properties. The agents may also contain salts of the said pyrimidine derivatives. Preferably the 4,6-(subst.)diamino-5-nitro-pyrimidines are also substituted in the 2-position, especially by methyl, ethyl, methoxy or trihalomethyl.

Abstract: Compounds of the formula ##EQU1## wherein R.sub.1 is lower alkyl or aryl,R.sub.2 is hydrogen or, together with R.sub.1, ethylene, andR.sub.3 is straight or branched alkyl of 8 to 22 carbon atoms;The compounds have useful therapeutic, dermatological and cosmetic properties.

Abstract: 1,3-Bis(halomethyl)phenobarbitals are prepared by reacting phenobarbital with formaldehyde and a chlorine source or a bromine source at a temperature of -10.degree. to 200.degree.C in the presence of a Lewis acid catalyst, the formaldehyde and bromine or chlorine source being employed in at least approximately twice the molar amounts of phenobarbital. These compounds are useful anticonvulsant agents.

Abstract: Side chain modification of 24-hydroxyimino-14a-aza-D-homo-cholesta-8(9), 14(14a)-dienes provides novel azasteroids having antifungal activities.