Patents Examined by Rosanne Kosson
  • Patent number: 11040079
    Abstract: The present invention discloses a cancer treatment method which includes the step of treating a patient having cancer with an extract from Galenia Africana L. plant. The extract may include pinocembrin and/or 2?,4? dihydroxychalcone and/or 7-hydroxyflavanone. The cancer may be breast cancer or melanoma. The composition may be solubilized with MPG and/or Suganate.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: June 22, 2021
    Assignee: BIOPHARM NZ LIMITED
    Inventor: Michael-John Joseph Barry
  • Patent number: 11040017
    Abstract: Cannabidiol (CBD) formulation comprising a mixture of full spectrum cannabidiol oil (FSO) and cannabidiol isolate (CBD isolate) is disclosed. The formulation contains a total amount of CBD derived from a combination of an amount of CBD in the FSO and an amount of CBD from the CBD isolate. The formulation of FSO and CBD isolate in used for medicinal and health benefits in a wide range of products, such as tinctures, capsules, creams or lotions, bath salts or bombs, soaps, pet or animal tinctures, and pet or animal edible chews.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: June 22, 2021
    Assignee: Healthy Roots Inc.
    Inventor: Elizabeth Merritt
  • Patent number: 11026987
    Abstract: The present disclosure relates to a composition for preventing, treating or remedying female climacteric syndrome symptoms, which contains an extract of Pueraria thomsonii flower or bud. The composition according to the present disclosure shows quick effects for preventing, remedying and/or treating female climacteric syndrome symptoms, particularly facial flushing and/or osteoporosis, and thus can be utilized for the hormone replacement therapy (HRT) used for preventing or remedying climacteric syndrome symptoms.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: June 8, 2021
    Inventors: Bo-Young Lee, Ho-Song Cho, Soon-Ran Song, Won-Kyung Lee, Jeong-Hoon Jeon, Chang-Il Choi, Sang-Hwa Lee
  • Patent number: 11026981
    Abstract: The present invention relates to a low-density lipoprotein (LDL)-cholesterol-lowering preparation, in particular to a bacterial cell extract for use as a medicament for lowering of the blood plasma LDL-cholesterol level, wherein the extract is obtained by extraction for between 10 minutes and 48 hours at between 8° C. and 37° C., while mixing the cells with the mixture, and wherein the ldl-cholesterol-lowering cell extract and food supplementldl-cholesterol-lowering cell extract and food supplement Rhodospirillum rubrum cells are extracted with the mixture in a volume ratio of between 10:1 and 1:10 of petroleum ether with a boiling point of between 60° C. and 80° C. and methanol comprising sodium chloride. More specifically, the present invention relates to a petroleum ether extract of Rhodospirillum rubrum obtainable by extraction of Rhodospirillum rubrum cells with a mixture of petroleum ether with a boiling point of between 60° C. and 80° C. and methanol comprising sodium chloride.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: June 8, 2021
    Assignee: ezCol B.V.
    Inventors: Ruddy Wattiez, Felice Mastroleo, Robertus Christiaan Josephus Suters
  • Patent number: 11028424
    Abstract: A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: June 8, 2021
    Assignee: Promega Corporation
    Inventors: Keith V. Wood, Georgyi V. Los, Robert F. Bulleit, Dieter Klaubert, Mark McDougall, Chad Zimprich
  • Patent number: 11020440
    Abstract: The use of orally administrable compositions comprising Streptococcus salivarius is described, for the prevention or the treatment of psoriasis in all its forms. In particular, the present invention relates to the use of compositions comprising Streptococcus salivarius, for the treatment of psoriasis in all its forms.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: June 1, 2021
    Inventors: Stefano Di Girolamo, Laura Diluvio, Arianna Zangrilli
  • Patent number: 11020437
    Abstract: The present invention relates to the use of eggshell membrane compositions to activate levels of nuclear factor kappa-light-chain-enhancer of activated B cells (“NF-?B”) in the gut of a host in need thereof and methods of treating conditions related to NF-?B dysregulation.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: June 1, 2021
    Assignee: ESM TECHNOLOGIES, LLC
    Inventor: Kevin J. Ruff
  • Patent number: 11022528
    Abstract: The clarity method for biotissue using a biotissue clearing agent including CHAPS of the present invention enables fast tissue clarity without denaturation.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 1, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Sun Hyun Park, Ki-Suk Kim, Dae-hwan Nam
  • Patent number: 11016081
    Abstract: The present invention generally relates to an apparatus, method, system for the determination of the aggregation rate of red blood cells. More specifically, the invention concerns a method, system, and the relative apparatus used to determine the aggregation rate of red blood cells, and other parameters related to these, such as viscosity, deformability, elasticity, density, in the field of in vitro medical analyses, using optical systems after or during inducted forces for red blood cell disruption and redistribution generated by ultrasound waves.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: May 25, 2021
    Assignee: Alcor Scientific Inc.
    Inventors: Peter Sacchetti, Francesco Frappa
  • Patent number: 11007240
    Abstract: Disclosed are uses of ginseng saponin, which contains at least 90% of a compound K, Rd, F2, and Rg3 as a main ingredient and has effects in extending the lifespan of the cell, promoting the cell differentiation, increasing the number of red blood cells, and reducing the triglycerides by extracting, heat-treating, and enzyme-converting the ginseng saponin to prepare active saponins Rd, F2, and Rg3 including a compound K.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: May 18, 2021
    Assignee: KOREAN DRUG CO., LTD.
    Inventors: Jae Seon Kang, Bo Suel Kim, Heyong-Soo Kim, Gyu-Jin Rho, Sin-Ja Bae, Seo Hyun Lee, Jong Jin Park, Choel-Min Kim
  • Patent number: 11008549
    Abstract: Methods for mimicking a tumor microenvironment in vitro are provided. The methods comprise indirectly applying a shear stress upon at least one tumor cell type plated on a surface within a cell culture container. Methods for mimicking tumor metastasis and methods for testing drugs or compounds in such systems are also provided.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: May 18, 2021
    Assignee: Hemoshear, LLC
    Inventors: Brian R. Wamhoff, Brett R. Blackman, Robert A. Figler, Daniel G. Gioeli, Michael B. Simmers
  • Patent number: 10993976
    Abstract: A medicament for use in treating uremia and proteinuria, the medicament being a glycoprotein, a mixture of polysaccharide and protein, a polypeptide or a protein.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: May 4, 2021
    Assignee: SHANDONG ZHONGHAI PHARMACEUTICAL CO. LTD
    Inventors: Qian Cheng, Baozhen Xu, Long Cheng
  • Patent number: 10993955
    Abstract: A medicament for treating diabetes and complications thereof, the medicament being a glycoprotein, or a mixture of a polysaccharide and a protein, or a polypeptide, or a protein.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: May 4, 2021
    Assignee: SHANDONG ZHONGHAI PHARMACEUTICAL CO. LTD
    Inventors: Baozhen Xu, Qian Cheng, Long Cheng
  • Patent number: 10993979
    Abstract: Disclosed herein are botanical tinctures that can be variously formulated and packaged and used as dietary supplements and in the prevention and treatment of symptoms associated with disorders affecting digestion or the digestive tract (e.g., symptoms of functional gastrointestinal disorders, FGIDs).
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: May 4, 2021
    Assignee: The Trustees of Columbia University
    Inventor: Marc Brodsky
  • Patent number: 10986856
    Abstract: Disclosed are techniques and systems for producing microbials having anaplerotic oils that are rich in odd-chain fatty acids, and other beneficial components, at higher concentrations than those present in other natural dietary sources of OCFA, at lower cost, and higher production yield. Further, disclosed are examples of incorporation of these higher concentration OCFA products into food for human and non-human animal consumption.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: April 27, 2021
    Assignee: Heliae Development, LLC
    Inventors: Micheal LaMont, Magdalena Amezquita Ernult, Eneko Ganuza Taberna
  • Patent number: 10987392
    Abstract: The present invention provides a new method for preventing and controlling viral diseases in salmonid fish using Quillaja extracts, wherein said method comprises administering to salmonid fish an effective amount of a medicinal composition comprising a Quillaja saponaria extract as active ingredient.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: April 27, 2021
    Assignee: SAPONIN RESEARCH CENTER S.A.
    Inventors: Trinidad Schlotterbeck Suárez, Hernán Alberto Cañon Jones, Mario Hernán Castillo Ruiz, Hernán Danilo Cortés González, Ricardo Manuel San Martín Gamboa
  • Patent number: 10987383
    Abstract: The invention provides compositions comprising chitosan, manuka honey and one or more additional components that promotes digestive health (e.g., inulin, probiotics) for the treatment and prevention of gastric ulcers (esophageal, stomach, or duodenum) in a mammal (e.g., equine).
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: April 27, 2021
    Assignee: Promend Animal Health, Inc.
    Inventors: Scott P. Noel, William Brian Austin, Alex Greene, John Kirk Shumpert
  • Patent number: 10987393
    Abstract: The present invention discloses a new method for preventing and controlling bacterial diseases in salmonid fish using Quillaja extracts, wherein said method comprises administering to salmonid fish an effective amount of a medicinal composition comprising a Quillaja saponaria extract as active ingredient.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: April 27, 2021
    Assignee: SAPONIN RESEARCH CENTER S.A.
    Inventors: Trinidad Schlotterbeck Suárez, Hernán Alberto Cañon Jones, Mario Hernán Castillo Ruiz, Hernán Danilo Cortés González, Ricardo Manuel San Martín Gamboa
  • Patent number: 10973864
    Abstract: The present application provides a safe, efficient, environmental friendly and convenient method for an enzyme assisted lipid-based extraction and stabilization of phyto-cannabinoids and terpenes/terpenoids from plant materials. The lipid-based extract presents high cannabinoid content and enhanced phyto-cannabinoids and terpenes/terpenoids stability, and it can be valorized toward multiple applications in the health, cosmetic, food and agricultural sectors.
    Type: Grant
    Filed: January 15, 2018
    Date of Patent: April 13, 2021
    Assignee: HERBOLEA BIOTECH S.R.L.
    Inventor: Giovanni Venturini Del Greco
  • Patent number: 10966948
    Abstract: The present invention relates to compositions comprising one or more extracts and/or compounds having retinol-like activity and properties and methods of using the compositions to treat the eye.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: April 6, 2021
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventors: Wen-Hwa Ting Li, Khalid Mahmood, Ramine Parsa, Mingqi Bai, Kenneth T. Holeva