Patents Examined by Rosanne Kosson
  • Patent number: 11311592
    Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: April 26, 2022
    Assignees: ACADEMIA SINICA, INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chang-Jen Huang, Rita P.-Y. Chen, Yung-Feng Liao, Bo-Kai Wu, Po-Ting Chen, Hui-Ping Tsai, Yi-Cheng Cheng, Cheng-Li Fang, Hung-Chi Chien, Tien-Soung Tong, Ting-Shou Chen, Shu-Jiau Chiou
  • Patent number: 11299756
    Abstract: A therapeutic serum suitable for inclusion in a cosmetic preparation may be produced by stressing a co-culture including proliferative cells. The co-culture of cells may be obtained by growing first culture to less than one-hundred percent confluence on a surface. After a monolayer of first culture is established, a second culture may be seeded onto at least one cell free area on the surface, the resulting co-culture grown to less than one-hundred percent confluence. Additional cultures may then be seeded onto cell free areas of the surface and established until a monolayer having the desired population of cells is obtained. The monolayer is then stressed to obtain a serum by conditioning a collection medium. The obtained serum may be combined with a suitable cosmetic base to provide a cosmetic preparation.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: April 12, 2022
    Assignee: SERUCELL CORPORATION
    Inventor: Walter De Paula Neto
  • Patent number: 11298384
    Abstract: This invention relates to a composition for use in the treatment of major depressive disorder. In addition, this invention relates to a composition for use in the treatment and/or improvement of mood disturbances and for use in the treatment and/or improvement of the mood state.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: April 12, 2022
    Assignee: PROBIOTICAL S.P.A.
    Inventor: Giovanni Mogna
  • Patent number: 11285187
    Abstract: The present invention relates to a Petasites extract or pharmaceutical composition thereof for use in a method for treating viral infections.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: March 29, 2022
    Assignee: MAX ZELLER SOEHNE AG
    Inventors: Jurgen Drewe, Stephan Toff, Catherine Zahner
  • Patent number: 11278575
    Abstract: The present disclosure provides compositions and methods for treating demyelinating conditions. More particularly, the present disclosure relates to compositions including DUOC-01 cell product and an anti-inflammatory agent; methods for preparing such compositions; and methods of using such compositions in combination or in conjunction with each other for treatment of treating demyelinating conditions.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 22, 2022
    Assignee: Duke University
    Inventors: Joanne Kurtzberg, Andrew E. Balber, Arjun Saha, Pamela Noldner, Paula Scotland
  • Patent number: 11273186
    Abstract: The present invention discloses an application of Bacteroides cellulosilyticus in preparing a preparation for preventing and/or treating lipid metabolism related diseases, such as atherosclerosis related diseases, cardiovascular diseases and obesity.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: March 15, 2022
    Assignee: BGI SHENZHEN
    Inventors: Zhuye Jie, Suisha Liang, Huihua Xia, Yuanqiang Zou, Liang Xiao, Huijue Jia
  • Patent number: 11268062
    Abstract: Spent stillage remaining after the fermentation of a feedstock for ethanol production may be processed to recover, use, and/or recycle the constituent components of the stillage. Stillage may be mixed, heated, and held at a desired temperature for a period of time. The stillage may then be cooled and treated with an enzyme. The enzymatically treated stillage may be emulsified with oil and water, and then permitted to settle into discrete layers. Individual layers may then be processed.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: March 8, 2022
    Assignee: LucasE3, L.C.
    Inventor: Scott A Lucas
  • Patent number: 11260088
    Abstract: Disclosed are nutritional compositions including 2?-fucosyllactose (2?-FL) in combination with lutein and RRR-alpha-tocopherol. The nutritional compositions are useful for improving at least one of gut function, health, and development in an individual. In certain embodiments, the nutritional compositions can improve growth or maturation of the gut, as well as promote a healthy balance of beneficial bacteria in the gastrointestinal tract thereby treating and/or preventing formula intolerance or other gastrointestinal diseases and/or disorders resulting from suboptimal gastrointestinal flora population/balance.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: March 1, 2022
    Assignee: ABBOTT LABORATORIES
    Inventors: Alejandro Perez Barranco, Maria Gonzalez Ramirez, Rachael Buck, Enrique Hernandez Vazquez
  • Patent number: 11253561
    Abstract: The present invention provides nutritional compositions that are employed as oral supplementation to the human diet and methods for using such nutritional compositions. The compositions of the present invention provide for supplementation to the diet of the cancer patient, as well as preventative dietary supplementation aimed at supporting the human immune system for those not currently suffering from cancer. Methods are provided that utilize specific combinations of selected forms selenium. chromium, and molybdenum in combination with fish oil.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: February 22, 2022
    Inventor: Houn Simon Hsia
  • Patent number: 11254962
    Abstract: The present invention provides a method for preparing salidroside. The present invention uses ?-glucoside and CoFe2O4 particles to form a cross-linked aggregate capable of effectively catalyzing the reaction of ?-D-glucose and tyrosol, thereby increasing the yield of the salidroside. The steps of the preparation method of the present invention are simple and short, and the method is easy to operate and readily applicable to industrial production.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: February 22, 2022
    Inventors: Caihong Zhao, Jicheng Gui, Maodong Liu, Zhaolin Mao, Yingjun Geng, Langjun Cui
  • Patent number: 11246841
    Abstract: The subject invention pertains to methods and compositions for the treatment of erectile dysfunction (ED) (e.g., impotence) in a subject in need thereof utilizing one or more cannabinoid and one or more anti-ED drug.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: February 15, 2022
    Inventor: James J. Caprio
  • Patent number: 11246312
    Abstract: Disclosed herein are antimicrobial compositions that are substantially odorless. The antimicrobial compositions can comprise, for example, a first essential oil and a second essential oil, wherein the composition is substantially odorless. In some examples, the composition can further comprise a third essential oil. The compositions described herein can, for example, reduce the population of microbes, such as Staphylococcus aureus or Escherichia coli, by 5 log or more. Also disclosed herein are beverages and food products including the compositions disclosed herein. Also disclosed herein is milk including the compositions disclosed herein. Also disclosed herein are methods for treating or preventing a microbial infection in a subject, the methods comprising administering to the subject an effective amount of any of the compositions disclosed herein. Also disclosed herein are methods for combating bovine mastitis, the methods comprising applying any of the compositions disclosed herein to cow udders.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: February 15, 2022
    Assignee: CROWPIERCE TECHNOLOGIES, LLC
    Inventors: George Pierce, Sidney Crow, Amber Keller
  • Patent number: 11246892
    Abstract: A composition and method for ameliorating drug-seeking behavior in drug addicts who have stopped using the addicted-to drug and who have reestablished non-addict physiological chemical balance.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: February 15, 2022
    Inventor: Ajibike Omosalewa Salako-Akande
  • Patent number: 11241406
    Abstract: Disclosed herein are compositions and methods for acutely raising nitric oxide levels in a subject. In one example, the composition can include, an effective amount of a NOS dependent source of nitric oxide; an effective amount of a NOS independent source of nitric oxide; and an effective amount of a myeloperoxidase inhibitor; wherein the composition acutely raises nitric oxide levels in a subject above a level provided by the available sources of nitric oxide in the subject prior to administration of the composition. Further presented is a method of treating a subject for a condition or disorder that is response to nitric oxide therapy, including: acutely raising nitric oxide levels in a subject by simultaneously increasing biosynthesis of nitric oxide, increasing nitrate/nitrite levels, and inhibiting myeloperoxidase activity.
    Type: Grant
    Filed: August 28, 2016
    Date of Patent: February 8, 2022
    Assignee: Nature's Sunshine Products, Inc.
    Inventors: Matthew L. Tripp, Clinton J. Dahlberg, John G. Babish, Mohan Kaadige, Wei Gao
  • Patent number: 11236301
    Abstract: Thin film devices, e.g., multilayer thin film devices, that encapsulate cells for transplantation into a subject are provided. Also provided are methods of using and methods of preparing the subject devices. The thin film devices include a first porous polymer layer and a second porous polymer layer that define a lumen therebetween and encapsulate a population of cells within the lumen. The thin film devices can promote vascularization into the lumen of the device via the pores in the first polymer layer and/or second polymer layer; limit foreign body response to the device; limit ingress of cells, immunoglobulins, and cytokines into the lumen via the first and the second polymer layers; and release from the first polymer layer and/or the second polymer layer molecules secreted by the population of cells.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: February 1, 2022
    Assignee: The Regents of the University of California
    Inventors: Tejal Ashwin Desai, Crystal Nyitray, Ryan Chang
  • Patent number: 11229670
    Abstract: The present invention relates to a gingival fibroblast-derived product for use in the treatment or prevention of an immune-related disease in an individual.
    Type: Grant
    Filed: November 18, 2017
    Date of Patent: January 25, 2022
    Assignee: SCARCELL THERAPEUTICS
    Inventors: Antoine Lafont, Bernard Coulomb
  • Patent number: 11229671
    Abstract: Bacterial species acting as biomarkers for obesity in domesticated cats and/or dogs are disclosed herein. Also disclosed are methods for diagnosing and/or treating cats and/or dogs having obesity or a predisposition to obesity as well as methods of screening for agents to treat or prevent obesity.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: January 25, 2022
    Assignee: Gnubiotics Sciences SA
    Inventor: Adeyemi Adesokan
  • Patent number: 11224624
    Abstract: Some embodiments relate to genetically engineered bacterial strains for modulation of levels of the bacterial metabolite 4-ethylphenol (4EP) and its sulfated form, 4-ethylphenyl sulfate (4EPS). In some embodiments, the bacteria reduce or inhibit production of 4EP or 4EPS in the gut of a subject. The bacteria can ameliorate, delay the onset or reduce the likelihood of one or more symptoms associated with anxiety and/or autism spectrum disorder (ASD) in the subject.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: January 18, 2022
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Brittany D. Needham, Sarkis K. Mazmanian, Gil Sharon, Masanori Funabashi, Michael A. Fischbach, Elaine Y. Hsiao, Paul H. Patterson
  • Patent number: 11207357
    Abstract: Described herein are compositions and methods of treatment for acne and other skin disorders involving the use of probiotics. In certain aspects, microbes included in the probiotics have been engineered or selected for the treatment of specific skin disorders.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: December 28, 2021
    Assignee: SYMBIOME, INC.
    Inventors: Emma Taylor, David Hanzel
  • Patent number: 11202815
    Abstract: The present invention relates to a composition for preventing, treating or improving a prostate disease containing Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora extracts as an active ingredient. According to the present invention, the complex extract of Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora has an effect of inhibiting the activity of 5?-reductase associated with benign prostatic hyperplasia and has an advantage of having a few or no side effects of reducing a male sexual function by using a synthetic compound in the related art using ingredients derived from natural plants. Further, it is confirmed that in a complex extract obtained by mixing Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora extracts at a more proper ratio, the 5?-reductase inhibitory activity is significantly excellent.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: December 21, 2021
    Assignee: GENOME & MEDICINE CO., LTD.
    Inventors: Min Won Lee, Kyu Hyeong Yoon, Yoon Ok Lee, Sung Hye Youn, Jae Seung Yoon