Abstract: Viable biomaterial such as animal cells, plant cells, bacteria, algae or fungi are immobilized with retained ability of growth by encapsulation in polymer beads. Encapsulation is carried out by adding the biomaterial to an aqueous solution of a polymer such as agar, agarose, carrageenan, chitosan, gelatin, collagen or fibrinogen, dispersing the solution in a water-insoluble dispersion medium such as soybean oil, tri-n-butylphosphate, liquid silicone, paraffin oil or phthalic acid dibutylester and allowing the polymer to gel.

Abstract: Vaccine prepared by inactivation of non-enveloped virus with cis-diamino chelated platinous halide in presence of an effective amount of a detergent. Method of inactivation particularly applicable employing a non-ionic detergent in inactivating a double stranded RNA virus.

Abstract: The invention relates to a process for the preparation of the lyophilized vaccine against duck hepatitis by using the attenuated hepatitis virus TN cultivated by Asplin.According to the invention the virus deposited in the Strain Collection of the Hungarian Institute of Public Healts under No. 00220 is injected into the allantoic cavity of embryonated SPF-hen's eggs, the eggs are incubated at a temperature of about 37.degree. C., the embryos died between 24 and 96 hours are collected, homogenized with a physiological saline solution, antibiotics are added to the pure suspension, and after the addition of protective and skeleton forming agents the sterile virus material is lyophilized in a manner known per se.The lyophilized vaccine can be stored at a temperature of +4.degree. C. for one year in contradiction to the known liquid vaccine storable in freezed state at a temperature of -20.degree. C. for half a year and which has to be used within 7 days from the delivery (with a storage temperature of +4.degree.

Abstract: A live bovine viral diarrhoea (BVD) virus vaccine capable of producing immunity in bovines without causing significant side effects comprising a temperature sensitive (ts) mutant of BVD virus which is obtained by mutating a strain of BVD virus with nitrous acid. The temperature sensitive mutants show a replication ability considerably limited at the animal body temperature of 39.5.degree. C. The vaccine may be combined with other live bovine vaccines such as respiratory virus vaccines and then administered to bovines.

Abstract: Normal plasma from donors who have not been vaccinated with a cytomegalovirus vaccine can be screened for higher than normal titers of naturally occurring antibody to cytomegalovirus. Those plasmas with high titers of such antibody can be pooled and fractionated to give hyperimmune serum globulin. The product may be treated to render it suitable for intravenous injection. Patients with cytomegalovirus infection or at risk to such infection, may receive the present product to raise serum titers of cytomegalovirus antibody.

Abstract: A method of inactivating a lipid virus contained in a dry protein carrier by contacting said virus-containing protein carrier for an abbreviated period of time at from 4.degree.-40.degree. C. with a composition including a halohydrocarbon treating agent and water dissolved in said treating agent. Preferred lipid viruses are Hepatitis B virus (HBV) and non-A, non-B Hepatitis (NANBH) virus.

Abstract: A diagnostic urine culture apparatus for catheterized urine collection, bacterial detection and bacterial identification, includes a culture tube, a typing medium, a tube cap means, a catheter means where the catheter means extends through an annular opening in the cap means and into the interior of the apparatus, the apparatus thus adapted to the collection and culturing of urine with minimal contamination of the sample.

Abstract: The compressing aid consists of particles of a Fischer-Tropsch synthetic saturated hydrocarbon wax having an average molecular formula of C.sub.48 H.sub.98, an average molecular mass of about 700, a minimum congealing point of about 204.degree. F. and an average particle size of about 10 microns. For greater ease and dispersion during blending of the ingredients, the wax particles may be coated with 0.1 to 1.0% by weight of a lubricant such as dimethyl polysiloxane, isopropyl myristate, lauryl lactate or ethylhexyl palmitate. As an alternative to using these lubricants, coating the surface of the wax with about 0.10-0.20% of a protein zein of corn gluten lubricates the fine wax and aids in its dispersion in the particle mixture. In many applications the vegetable protein lubricant is preferably because less pressure is needed to compress the mixture than with the lubricants noted above.

Abstract: Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxo-carbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.

Abstract: A hydrophilic therapeutic material comprising a carrier and a drug-containing patching layer formed thereon directly or indirectly, wherein said patching layer comprises a copolymer of 5 to 75% by weight of an acrylic or methacrylic ester having an ether group in the molecule, 85 to 15% by weight of an alkyl acrylate or alkyl methacrylate and 10 to 50% by weight of a polar monomer copolymerizable therewith.

Abstract: A cosmetic composition for make-up containing an N-acylamino acid salt or Al, Mg, Ca, Zn, Zi or Ti which may contain a pigment and/or an extender pigment treated with one or more of the N-acylamino acid metal salts.

Abstract: A method for the production of allergenic extracts comprising the extraction of an allergenic substance with a suitable solvent having incorporated therein a small but effective amount of a compound of the formula, ##STR1## wherein Y is H or lower alkyl; Z is CH.sub.2 ; n is 0 or 1; R is alkylene or cycloalkylene; m is 0 or 1; W is CH.sub.2 ; and X is H, acyl or lower alkyl. The novel allergenic extracts produced by this process are also the subject of this invention.

Abstract: Cosmetic and skin treatment compositions are provided which include as emollients acetylated soy bean derived sterols, namely, acetylated sitosterol, acetylated campesterol, and/or acetylated stigmasterol. The above-acetylated sterols impart improved hand feel and barrier properties to the compositions, are naturally compatible with skin and have improved skin penetration properties over unesterified sterols.

Abstract: A column reactor, suitable for continuous production of a gaseous reaction product by contacting a liquid reaction medium with a gas-forming agent fixed to a reaction plug comprising a solid substrate provided with a plurality of gas-forming channels. The column reactor overcomes the apparent short circuiting of liquid reaction medium through the reactor by being provided with two or more reaction zones, each zone having its own circulatory by-pass means for liquid reaction medium. To obtain the reaction zones a reaction plug can be divided into two or more spaced apart plug portions. For each reaction zone the circulatory by-pass means provides a portion of the pathway for an internal recirculation current of liquid reaction medium.

Abstract: Nail lacquer compositions comprising a polymer resin consisting essentially of units resulting from the copolymerization of:(1) 75 to 97% by weight of at least one monomer having the general formula: ##STR1## in which: R.sub.1 represents an hydrogen atom or a methyl radical, andR.sub.2 represents a linear alkyl radical or a branched radical having 1 to 18 carbon atoms, a mono or dihydroxy alkyl radical, the alkyl radical having from 2 to 4 carbon atoms, a glycidyl radical or the radical --(CH.sub.2).sub.n --OR', wherein R' represents methyl or ethyl and n is 3 or 4, and(2) 3 to 25% by weight of at least one monomer selected from the group consisting of N-vinylsulfonamide, 4-styrenesulfonamide, acrylamide, methacrylamide, N-(N'N',3-dimethylaminopropyl) methacrylamide and N-(N'N',3-dimethylaminopropyl) acrylamide.

Abstract: A method of reducing local adverse reactions which occur at the site of administration of parenterally administrable physiologically active compositions, to patients which comprises, prior to administration thereof, incorporating in said physiologically active compositions, a small but effective amount of a compound of the formulae, ##STR1## wherein n is an integer of from 1 to 6; R.sup.1 is H or lower alkyl; x is 0 or 1; each Y is H; and R is H, lower alkyl or acyl; and the non-toxic pharmaceutically acceptable salts thereof.

Abstract: The method of improving the storage stability of parenterally administerable physiologically active compositions which comprises, incorporating in said compositions a small but effective amount of a compound of the formulae, ##STR1## wherein R is H, lower alkyl or acyl; each R.sup.1 is H or lower alkyl; and n is an integer of from 1 to 6; x is 0 or 1; each Y is H; and the non-toxic pharmaceutically acceptable salts thereof.

Abstract: The compressing aid consists of particles of a synthetic saturated hydrocarbon wax having an average molecular formula of C.sub.48 H.sub.98, an average molecular mass of about 700, a minimum congealing point of about 204.degree. F. and an average particle size of about 10 microns. For greater ease in dispersion during blending of ingredients, the wax particles may be coated with 0.1 to 1.0% by weight of a lubricant such as dimethyl polysiloxane and low viscosity esters of C.sub.10 to C.sub.18 fatty acids or alcohols such as isopropyl myristate, lauryl lactate and ethylhexyl palmitate.

Abstract: To regulate the immune response to an antigen, a subject is injected with the antigen and a polyanionic polysaccharide derivative having a molecular weight of between 10,000 and 600,000 selected to correspond to the antigen. For virus, as an example, mycodextran sulfate or pustulan sulfate may be used in sufficient quantities to stimulate cell-mediated immune responses without stimulating synthesis of gamma E globulin and gamma G globulin. The polyanionic polysaccharide may be injected along to stimulate cell-mediated immune responses to antigens in a diseased subject.

Abstract: An in vitro enzymatic process which efficiently converts (+,-)-tropicamide to essentially pure (+), (-)-tropicamide O-.beta.-D-glucuronide. This product is then separated, advantageously, into the novel compounds (+)-tropicamide O-.beta.-D-glucuronide and (-)-tropicamide O-.beta.-D-glucuronide. The products disclosed herein absorb ultraviolet light, and, thus, can be incorporated into suitable plastic films which are then useful for screening out harmful ultraviolet radiation for the protection of packaged goods. Also, the products can be used to protect the skin against burning by sunlight.