Abstract: A composition comprising a resorbable aqueous gel having dissolved or dispersed therein one or more water-soluble medicaments is of use in the treatment of wounds.Such a composition is of use in a method of healing an infection in a cavity in bone or other tissue whereby the resorbable aqueous gel is placed in the cavity and allowed to remain there until resorbed, the aqueous phase of the gel containing the water soluble medicament.The medicament is preferably an antibiotic or a methylol transfer antibacterial.

Abstract: The present invention relates to processes for preparing optically-active 4-amino-3-hydroxybutyric acid by asymmetrically cleaving one of the enantiotopic ester groupings of 3-hydroxyglutaric diester by the action of microbial enzymes to obtain a chiral monoacid which is readily converted into optically-active 4-amino-3-hydroxybutyric acid by chemical means.

Abstract: A method of inactivating a lipid virus in a protein carrier by contacting said virus for an abbreviated period of time and ambient temperature with a halohydrocarbon solvent or treating agent, preferably chloroform, in an amount of 5% v/v to 50% v/v. Preferred lipid viruses are Hepatitis B virus (HBV) and non-A, non-B Hepatitis (NANBH).

Abstract: Unexpectedly high amounts of pigment can be incorporated in anhydrous, pigmented cosmetic compositions containing an organically substituted polysiloxane by providing the pigment in a hydrophobic silicone coating.

Abstract: An improved immunoassay for determining the presence of an analyte in a serum sample and conjugates therefor are described. The known method comprises combining the sample with a conjugate of the analyte and an enzyme and with a receptor for analyte, and determining the presence of analyte in the sample from the effect that the sample has on the enzymatic activity when compared to the enzymatic activity in the absence of analyte or in the presence of known amounts of analyte. The present invention resides in the conjugation to the enzyme label of a label protectant which allows modulation of the enzymatic activity to occur and minimizes background interference between the enzyme label and the sample, which would alter the enzymatic activity.

Abstract: Cosmetic products which do not suffer phase separation comprise a mixture of a cosmetically acceptable wax with dimethylpolysiloxane and either an organosilane or an organically substituted polysiloxane.

Abstract: Immobilized enzyme granules prepared by mixing inert filler particles into an aqueous solution or dispersion of a water soluble binder, followed by granulating the mixture so as to form carrier granules. Enzyme is immobilized on the hydrophilic surfaces of the carrier granules. If not already insoluble in the medium for the intended enzymatic reaction, the binder in the granules is rendered insoluble, e.g., water insoluble.Proteins are preferred binder materials, and glutaraldehyde is the preferred reagent for bonding enzyme to the carrier granules and for water insolubilizing the binder.

Abstract: A process for leaching copper from copper sulphide containing ore, in particular copper from chalcopyrite containing ore, is provided. The ore is preferably initially ground up and mixed with an aqueous acid leaching medium containing sulphide oxidizing bacteria, and a bacterial nutrient, and a catalytic amount of silver. Provision is made in the bacterial nutrient for a source of carbon dioxide and oxygen for the bacteria, both of which may be supplied by means of sparging with carbon dioxide enriched air. A bacterial compatible acid is added initially to the ore and leaching medium mixture and periodically during the process so that sulphide in the copper sulphide is oxidized in stoichiometric amounts to elemental sulphur. During leaching the oxidation potential is maintained between about 0.54 to 0.66 volts, most readily by initial addition of thiosulphate and dissolved copper.

Abstract: Described are thymidine kinase negative temperature resistant mutants of bovine herpesvirus effective in inducing resistance to infectious bovine rhinotracheitis, methods for their production, methods for maintaining them in viable form, and methods for administering them to animals in immunologically effective doses to induce resistance to infectious bovine rhinotracheitis.

Abstract: The disclosure relates to novel synthetic thiopeptolide substrates having high activity for the enzyme collagenase. These substrates have the following amino acid sequences:R-Pro-X-Gly-S-Y-Z-Gly-R.sub.1whereinR=H or N-protecting group,X=Leu, Ile, Phe, Val, Gln, Ala,Y=Leu, Ile, Phe, Val, Ala,Z=Leu, Ile, Phe, Val, Gln, Ala, andR.sub.1 =terminal amide, carboxyl or ester group.

Abstract: Body powder compositions exhibiting excellent moisture absorbency comprising starch and a specific pregelatinized cornstarch.

Abstract: An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for propagation of the Canine Corona virus and its attenuation and a method of evaluating the effectiveness of a Canine Corona virus vaccine in canines is also disclosed.

Abstract: An efficacious parenterally administered inactivated canine coronavirus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent canine coronavirus is produced. A method for propagation of the canine coronavirus and its attenuation and a method of evaluating the effectiveness of a canine coronavirus vaccine in canines is also disclosed.

Abstract: A process for producing a hepatitis B infection preventing vaccine containing hepatitis B surface antigen as a main component thereof which comprises removing human plasma components possibly causing adverse effects and components capable of causing hepatitis B infection by incorporating steps of fractionation using ammonium sulfate, adsorption on a colloidal silicate and fractionation using polyethylene glycol into the purification stage after heat treatment and further carrying out a treatment for infectivity inactivation without causing any antigenicity impairment.

Abstract: Hair shampoo and body cleansing agent having a content of alkyl-sulfatobetaine of the formula ##STR1## wherein R.sub.1 is C.sub.8 -C.sub.22 alkyl or C.sub.8 -C.sub.22 alkenyl, preferably C.sub.12 -C.sub.18 alkyl, R.sub.2 is C.sub.1 -C.sub.4 alkyl, preferably methyl, R.sub.3 is C.sub.1 -C.sub.4 hydroxyalkyl or a group of the formula --(CH.sub.2 CH.sub.2 O).sub.n H and n is an integer of from 1 to 10.

Abstract: A controlled release agglomerated carrier for pesticides and the like comprised of preselected portions of the pith, fine and coarse chaff and woody ring portions of a corncob which, when combined in varying ratios, define an overall release rate for the carrier and/or act as a bait for the targeted species.

Abstract: Composition and method are provided for enzyme immunoassays for high molecular weight proteins, such as ferritin. An enzyme is conjugated to the high molecular weight protein through a specific linking group. Usually, on the average, about 2 to 10 enzyme molecules are bonded to each protein molecule. In an assay, the conjugate competes with an unknown sample for receptor and the resulting enzymatic activity is compared to a standard for a determination of the presence and amount of protein in the unknown.

Abstract: A process of preparing a vaccine capable of protecting poultry against avian proventriculitis which comprises: separating proventriculitis reovirus from reovirus-carrying tissue of a poultry animal diseased with proventriculitis; inoculating a cell culture capable of sustaining the growth and replication of the reovirus; extracting the virus from cellular and nonviral components, and rendering the reovirus into a form suitable for administration to poultry, yields a vaccine and an immunization method.

Abstract: A method for dislodging cultured cells has the steps of preparing a culture container which has a growing surface on which cultured cells are grown, and which is filled with a culture solution in contact with the cultured cells, supporting the culture container on a pedestal to be reciprocally movable in a direction parallel to the growing surface, and reciprocally moving the culture container in the direction parallel to the growing surface and thus applying an inertial force on the cultured cells in the direction parallel to the growing surface, thereby dislodging the cultured cells from the growing surface. An apparatus for dislodging cultured cells has the pedestal for supporting the culture container and a reciprocating device for reciprocally moving the culture container supported on the pedestal in the direction parallel to the growing surface.

Abstract: The present invention provides multi-layered film preparations which comprise one or more water soluble polymer bases, one or more water insoluble polymer bases, one or more plasticizers and one or more prostaglandins, and optionally contain one or more organic acids, and they are composed of at least two drug release controlling layers and one or more drug storing layers. The multi-layered film preparations of the present invention are characterized by that the prostaglandin(s) containing therein exhibit the desired long-lasting release patterns at the concentration required for therapeutic purpose.