Abstract: The present invention relates to compositions comprising molecular iodine and a vehicle comprising a semifluorinated alkane. The compositions of the invention may be used to treat or prevent diseases or conditions caused by, or associated with microorganisms.

Abstract: This invention relates to an antimicrobial composition, especially one which provides synergistic anti-dandruff efficacy. This is achieved through a judicious combination of anti-dandruff agent zinc pyrithione and an alcoholic compound of specific types. These compositions can be delivered through very many different types of personal care products e.g. shampoo or conditioner.

Abstract: An object of the present invention is to provide a pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof at a high concentration, with a characteristic bitter taste masked, and a manufacturing method thereof. The present invention provides a pharmaceutical composition comprising fine granules having a core comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof, and a binder; and a polymer layer with which a surface of the core is coated, wherein the fine granules have a roundness of 0.8 or more and a content of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or the salt thereof in the fine granules is 30 to 90% by mass.

Abstract: A composition comprising, in a physiologically acceptable medium, a crosslinked hyaluronic acid (HA), having a degree of modification less than 1.9 mole %; a HA with a molecular weight of about 50 kDa or less; and/or an agent stimulating endogenous HA synthesis. Also disclosed is a cosmetic use of such composition in skin care and/or anti-ageing treatment.

Abstract: An organosilicon antimicrobial solution, an organosilicon antimicrobial agent, an antimicrobial glass, a preparation method therefor, and use thereof. The organosilicon antimicrobial solution comprises, in percentage by mass: 30% to 65% of an organosilicon quaternary ammonium salt; 10% to 40% of ethyl orthosilicate; 10% to 40% of a double bond-containing organosilicon; 5% to 20% of an epoxy group-containing organosilicon; 5% to 20% of methyltrimethoxysilane; and 0.1% to 3% of an organotin catalyst. The organosilicon quaternary ammonium salt is selected from at least one of methyldiethoxysilane quaternary ammonium salt, N,N-dimethyl-N-octadecylaminopropyltrimethoxysilane quaternary ammonium salt, (trimethoxysilylpropyl)octadecyldimethylammonium chloride and 3-(trimethoxysilyl)propyldimethyldodecylammonium chloride. An antimicrobial glass prepared by the organosilicon antimicrobial solution above has strong versatility and small influence on the light transmittance of the glass.

Abstract: Compositions related to polymeric rodenticides, methods of making, and methods of use related to rodenticides comprising polymers are generally described. Rodenticides described in some aspects comprise an active ingredient, an attractant, and a binder. The active ingredient may comprise a polymer, such as polyacrylate, which expands upon exposure to water. The rodenticide composition may contain the active ingredient in an amount of 50-80 wt. % versus the total weight of the composition. The attractant attracts the rodent to the composition, while the binder adheres the composition together. Upon consumption of the rodenticide composition by a rodent, the active ingredient expands in the stomach (e.g., upon exposure to water). The expansion of the active ingredient causes the rodent to feel satiated and not search for water and food, ultimately leading to the death of the rodent, often within two days. Certain embodiments described herein are also related to methods of making such compositions (e.g.

Abstract: A novel pharmaceutical composition is provided comprising beta-caryophyllene or a functionally equivalent derivative, analogue or pharmaceutically acceptable salt thereof in a base cream comprising triglycerides, phospholipid, water, wax, alcohol, with other minor constituents. The composition is useful to treat pain and/or inflammation, reduce fine lines and wrinkles, moisturize, and protect skin with anti-bacterial, anti-fungal and insect repelling properties.

Abstract: As described below, the present invention features compositions and methods for inhibiting inflammation in connection with an acellular template (e.g., an electrospun template). In one embodiment, the template is impregnated with an agent (e.g., N-?-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide (Cl-amidine)) that inhibits a peptidylarginine deaminase (e.g., PAD4).

Abstract: Rat attractant compositions attractive to the rat species Rattus norvegicus are disclosed, which compositions are constituted of compounds found in the headspace volatiles of male urine odor or female urine odor. Said compositions are respectively termed male pheromone blend (MPB) and comprises 2-heptanone, 4-heptanone, 3-ethyl-2-heptanone, 2-octanone, 2-nonanone, and 4-nonanone in a ratio of 10:100:10:1:1:10 respectively, or female pheromone blend (FPB) and comprises 2-methyl-butyric acid, 3-methyl-butyric acid, heptanal, hexanoic acid, 2-phenylacetaldehyde, nonanal, and decanal in a ratio of 20:20:10:30:5:20:10. Devices including the rat attractant compositions, and methods of using said rat attractant compositions, are also disclosed.

Abstract: The instant disclosure relates hair care compositions comprising ionic liquids or ionic mixtures. Ionic liquids or ionic mixtures are combined with a cosmetically acceptable carrier to form ready-to-use hair care compositions. The ionic liquids and the ionic mixtures are formed from; (1) thiolactic acid and/or one or more alkali metal or alkaline earth metal salts thereof; and (2) one or more amine compounds, and/or one or more ammonium cationic compounds, and/or one or more salts thereof. The ionic liquids, the ionic mixtures, and the hair care compositions comprising the ionic liquids or the ionic mixtures, are useful in methods for preventing hair damage, shaping hair, caring for hair, etc.

Abstract: Personal care compositions containing active ingredients and an anti-irritant combination of aloe and taurine are disclosed. Methods of preparing the personal care composition and uses of the personal care composition are also disclosed.

Abstract: The invention relates to a topical pharmaceutical composition comprising effective amount of ivermectin as an active agent, process of preparation thereof and method of treating dermatological conditions such as inflammatory lesions of rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acne form rashes, and the like.

Abstract: Described herein are ternary alloys of copper (Cu), aluminum (Al) and tin (Sn). For example, the ternary alloys can comprise between about 0.5 weight percent (wt %) and about 5 wt % Al and between about 0.5 wt % and about 5 wt % Sn. The chemical composition of the alloys can be tailored such that the alloy maintains antimicrobial effect over time and is resistant to tarnish. The alloys are also hypoallergenic. Articles of manufacture, particularly those for use in medical facilities, comprising the alloy (e.g., as a surface layer) are also described, as are methods of reducing the incidence of microbial infection by providing surfaces comprising the alloy.

Abstract: Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.

Abstract: The present invention relates to a method for forming a pattern by negative tone development (NTD) which is prepared by forming an anti-reflective coating composition layer comprising a photoacid generator between the substrate and the photoresist composition layer, and thus exhibits improved line width (CD) in the pattern and prevents pattern collapse owing to thorough activation of de-blocking of the photoresist composition layer during the exposure process.

Abstract: A topical composition comprising at least one retinoid, alfalfa extract, and at least one carrier and uses thereof.

Abstract: The present disclosure discloses a pH-sensitive starch-based microcapsule encapsulating a fat-soluble substance and a preparation method thereof, and belongs to the field of preparation of starch-based hydrogel microcapsules. The method of the present disclosure comprises performing acid hydrolysis on starch to obtain acid-hydrolyzed carboxymethyl starch, mixing the acid-hydrolyzed carboxymethyl starch with xanthan gum to obtain a compounded solution of starch and colloid, adding an emulsifier and the fat-soluble substance, emulsifying to obtain an emulsion, and drying to obtain the microcapsule.

Abstract: Compositions comprising polymers comprising one or more ketal, monothioketal, and/or thioketal bonds are provided, as well as related methods and kits. In some embodiments, a polymer may comprise one or more repeat units comprising one or more ketal, monothioketal, and/or thioketal bonds and a precursor of a pharmaceutically active agent. The precursor of the pharmaceutically active agent may be located in the backbone or may be a pendant group. The polymer may degrade in certain environments (e.g., aqueous environments, acidic environments, in vivo, etc.) to produce the pharmaceutically active agent and other biocompatible degradation products, such as certain ketones, alcohols, and/or thiols. Regardless of the location of the precursor of the pharmaceutically active agent in the repeat unit(s), the polymer may have a prolonged degradation time and/or release of the pharmaceutically active agent in certain environments.

Abstract: The present invention is concerned with dispersible compositions comprising rilpivirine or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. Such compositions are useful in the treatment of HIV infection and their dispersibility properties lend themselves to be useful in particular amongst the pediatric or geriatric population.

Abstract: A topical cosmetic composition is described for restructuring and protecting hair and scalp, as well as products for hair and scalp care involving the same.