Patents Examined by Vera Afremova
  • Patent number: 11512281
    Abstract: Endophytic microbial strains as biocatalysts isolated from fresh plant samples, their compositions, and methods of use thereof to enhance the growth and/or yield of a plant in the presence of reduced (synthetic or otherwise) nitrogen and phosphorus fertilizers are provided. The selected endophytic microbial strains serve as biocatalysts to solubilize organic (proteinaceous) nitrogen otherwise unavailable to plants for their nutritional needs. In addition, selected endophytic microbial strains serve as biocatalysts to solubilize mineral-P and mineralize organic-P otherwise unavailable to plants for their nutritional phosphate needs. Thus defined, biocatalysts will serve to replace or reduce the requirement of (synthetic or otherwise) nitrogen and phosphorus fertilizers.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: November 29, 2022
    Assignee: Biomineral Systems LLC
    Inventor: Nadia Adam
  • Patent number: 11504406
    Abstract: A probiotic combination for inhibition of vancomycin-resistant enterococci includes Bacillus coagulans, Lactobacillus rhamnosus CG, Lactobacillus reuteri, and Lactobacillus acidophilus. The probiotic combination can inhibit growth, host cell attachment, or virulence of vancomycin-resistant enterococci, and also can inhibit virulence gene expression of vancomycin-resistant enterococci. The virulence gene includes at least one of asa1, acm, ebpA, ebpB, ebpC, efaA, sagA, esp, sgrA, and scm genes.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: November 22, 2022
    Inventors: Shiuh-Bin Fang, Kun-Nan Tsai, Wei-Sheng Sun, Yu-Hsuan Ho, Yuarn-Jang Lee
  • Patent number: 11497777
    Abstract: The invention relates to a composition comprising a mixture of at least one strain of a bacterium of the genus Bacillus and at least one strain of lactic acid bacterium for use in the prevention of infections in farmed oviparous animals.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: November 15, 2022
    Assignee: MIXSCIENCE
    Inventors: Michel Layus, Alexandre Brame
  • Patent number: 11490643
    Abstract: The strain Lactobacillus casei AH077 (NCIMB12019) produces a polysaccharide and increases energy excretion. The strain acts to block fat absorption and is used in the prevention or treatment of obesity and obesity-related metabolic syndrome.
    Type: Grant
    Filed: March 30, 2021
    Date of Patent: November 8, 2022
    Assignee: PrecisionBiotics Group Limited
    Inventors: Barry Kiely, Eileen Frances Murphy, Selena Healy
  • Patent number: 11492649
    Abstract: The present disclosure provides methods for generating sugars from a cellulosic biomass. The methods combine treatment of the biomass using a high-shear milling device and saccharification of the biomass to partially hydrolyze the biomass. The biomass can be saccharified either after or simultaneously with the high-shear milling treatement. The partially hydrolyzed biomass is then separated into a solids stream with saccharification enzymes, and a liquid stream with sugars. The solids stream and associated enzymes are further incubated under saccharification conditions to produce additional sugars, or are recycled and added to fresh biomass, which is saccharified under high-shear milling conditions. The methods result in improved conversion of cellulosic biomass to glucose.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: November 8, 2022
    Assignee: Edeniq, Inc.
    Inventors: Deepak Singh, Sandra Jacobson, Kris Ramos, Prachand Shrestha
  • Patent number: 11478420
    Abstract: A formulation for vaginal administration comprising an effective amount of a composition of dried Lactobacillus cells and boric acid, with a carrier. The composition can include one or more antioxidants. Optionally, the composition is in a unit dosage form. Also provided are methods for making and using the composition.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: October 25, 2022
    Assignee: Grace Procurements LLC
    Inventor: Allison Krebs-Bensch
  • Patent number: 11471498
    Abstract: The present disclosure relates to a new probiotic strain of Lactobacillus brevis, isolated from pulque and exhibiting anti-cancer properties, as well as to compositions which contain said strain.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: October 18, 2022
    Inventors: Luis Bermudez Humaran, Edgar Torres Maravilla, Philippe Langella, Maria Elena Sanchez-Pardo
  • Patent number: 11473120
    Abstract: A reference test body for monitoring and/or verifying test conditions during a test of microbial barrier properties of at least one product, wherein the reference test body has a cavity, a nutrient medium, at least one opening, and at least one cover provided with a number of holes and covering the at least one opening. A constancy of test conditions can be monitored in this way. The invention further relates to an associated use, an associated test chamber, and an associated method.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: October 18, 2022
    Assignee: Aesculap AG
    Inventors: Selina Kammerer, Daniel Kiessling
  • Patent number: 11447740
    Abstract: A new lactic acid bacterium of the present invention produces, as an exopolysaccharide, a neutral polysaccharide having a structure in which N-acetylglucosamines are linked with each other via ?-1,6 bond, is obtained from a fig, has a hyaluronidase inhibitory, an anti-alcoholic damage activity effect, and the like, and is therefore useful in a food and drink, a medicine, a feed, a cosmetic and the like exerting an antiallergy effect, an anti-alcoholic damage effect, and the like.
    Type: Grant
    Filed: May 28, 2018
    Date of Patent: September 20, 2022
    Assignee: SONE FARM CO., LTD.
    Inventor: Masanori Sugiyama
  • Patent number: 11440827
    Abstract: A method of preparing and separating biopolymers and biopolymer fractions is useful for wastewater treatment applications from sewage sludge. The method comprising the steps of disrupting the bacterial cell walls of bacteria present in the sewage sludge by at least 75% to release the intracellular contents of the bacterial cells and separating the biopolymers from any contaminants present.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: September 13, 2022
    Inventor: Minh Son Le
  • Patent number: 11439172
    Abstract: Aquafeed, animal feed, and other food products, as well as nutritional and pharmaceutical compounds, chemicals and biomaterials are important commodities that can be produced at commercial scale by fermentation of microorganisms. The present invention provides a method for producing these valuable multi-carbon compounds from simple gas feedstocks, such as carbon dioxide, hydrogen and oxygen, by cultivating a consortium of microbial cells specially selected for this purpose in an aqueous culture medium. In addition to exploiting inexpensive feedstocks, such as waste industrial gas for this cultivation, the platform described herein also provides the advantage of removing carbon dioxide and other waste gases from industrial emissions, which would otherwise contribute to global climate change. Furthermore, the cultivation of a microbial consortium can provide highly nutritious components to a feed blend that might not be available from a monoculture.
    Type: Grant
    Filed: July 3, 2017
    Date of Patent: September 13, 2022
    Assignee: OAKBIO, INC.
    Inventors: Brian A Sefton, William J Coleman
  • Patent number: 11433107
    Abstract: This document provides bacterial compositions. For example, bacterial compositions having a combination of different bacterial strains formulated in a manner to maintain the stability of the bacteria are provided.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: September 6, 2022
    Assignee: Melaleuca, Inc.
    Inventor: Subhendu Nayak
  • Patent number: 11414641
    Abstract: A thin film culture device for detecting aerobic bacteria in a sample is provided. The culture device comprises a self-supporting substrate sheet having a first major surface and a second major surface; a cover sheet attached to the substrate sheet, a sample-receiving zone disposed between the substrate sheet and the cover sheet, a first layer comprising a substantially dry, cold-water-soluble first hydrogel-forming composition adhered to a portion of the sample-receiving zone; and a plurality of indicator agents disposed in at least one layer adhered to the substrate sheet or the cover sheet. The plurality of indicator agents comprises three indicator agents for detecting distinct glycosidase enzyme activities, an indicator agent for detecting an alkyl esterase enzyme activity, an indicator agent for detecting a phosphatase enzyme activity, and a redox indicator. A method of using the culture device is also provided.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: August 16, 2022
    Inventors: Sailaja Chandrapati, Tera M. Nordby
  • Patent number: 11412770
    Abstract: Provided is a novel gel-like food composition. The gel-like food composition contains 0.1 to 10 wt % of a free branched-chain amino acid, 1 to 12 wt % of a protein, and 104/g to 1014/g of a probiotic.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: August 16, 2022
    Inventors: Keiko Toyooka, Koichiro Hamada, Hiroshi Saitoh
  • Patent number: 11407972
    Abstract: Methods for stimulating in-vitro Paecilomyces hepiali or Hirsutella sinensis growth, and nutritional supplement formulations containing such fungal strains are disclosed and described. In some embodiments, such a method may include providing a an effective amount of a P. hepiali fungus strain for use as a stimulating agent on a culture medium for which H. sinensis is grown and regulating the temperature to induce and maintain the growth of the H. sinensis fungus. Alternatively, a P. hepiali fungus may be grown in a similar manner using H. sinensis as the stimulating agent. In some aspects, the growth of one fungus may be sequentially switched with the other in order to improve fungi potency.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: August 9, 2022
    Assignee: NSE Products, Inc.
    Inventor: Jai-Shi Zhu
  • Patent number: 11406100
    Abstract: The present invention provides a decellularized collagenous tissue and a method for processing an artificial heart valve containing the decellularized collagenous tissue. The method comprises immersing the decellularized collagenous tissue in a preservation liquid containing an ionic liquid until the size of the decellularized collagenous tissue remains stable in a non-liquid environment. The present invention also provides a preservation method, comprising immersing the decellularized collagenous tissue or the artificial heart valve containing decellularized collagenous tissue in the preservation liquid containing ionic liquid until the size of the collagen tissue remains stable in the non-liquid environment. The present invention also provides a decellularized collagenous tissue and an artificial heart valve containing the decellularized collagenous tissue processed by the method described above.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: August 9, 2022
    Inventors: Shengping Sam Zhong, Jing Liu
  • Patent number: 11400123
    Abstract: A combination product comprising an isolated strain of Bifidobacterium NCIMB 41003 and another strain which does not adversely interact with Bifidobacterium NCIMB 41003 improves gastrointestinal symptoms associated with IBS and improves one or more of mood, stress, anxiety, sleep quality and depression associated with IBS.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: August 2, 2022
    Assignee: PrecisionBiotics Group Limited
    Inventors: Barry Kiely, Eileen Frances Murphy, David Groeger
  • Patent number: 11382939
    Abstract: Provided is a pharmaceutical composition and food composition for treating or preventing a skin disease caused by abnormal growth of a skin bacterium or infection with a pathogenic microorganism. A composition comprising a lactic acid bacterium as an active ingredient, for suppressing bacterial abnormal growth, or preventing or ameliorating deterioration of skin condition caused by a bacterial abnormal growth, by oral intake thereof.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: July 12, 2022
    Assignee: Kirin Holdings Kabushiki Kaisha
    Inventors: Ryohei Tsuji, Toshio Fujii
  • Patent number: 11376288
    Abstract: Disclosed are methods of using probiotic compositions containing Lactobacillus plantarum, Lactobacillus rhamnosus, and Bifidobacterium animalis subsp. lactis. to prevent and/or treat urogenital infections in women by oral administration.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: July 5, 2022
    Assignee: SYNBALANCE SRL
    Inventors: Rosella Malanchin, Cristiana Piangiolino, Marco Boccarusso
  • Patent number: 11365387
    Abstract: The present invention relates to the field of culturing unicellular red algae (URA). The invention relates in particular to a method for culturing URA, characterised in that the culture medium includes milk permeate as the main contribution of at least one carbon source. The invention also relates to biomass which can be obtained by the method according to the invention, to the uses of said biomass and to the products that can include said biomass.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: June 21, 2022
    Assignee: FERMENTALG
    Inventors: Olivier Cagnac, Bruno Gehin, Marion Champeaud