Patents Examined by Vera Afremova
-
Patent number: 11766465Abstract: The present disclosure relates to as external composition for wound healing containing a Lactobacillus fermentation product, which comprises a Lactobacillus fermentation product as an effective component. The Lactobacillus fermentation product is a bacteria-free concentrated filtrate from fermentation of Lactobacillus plantarum and the effective component is loaded onto a pharmaceutically acceptable absorbent carrier or carrying agent. The external composition for wound healing has anti-inflammatory and healing promoting effects on a skin wound after applied directly onto the skin wound.Type: GrantFiled: October 29, 2021Date of Patent: September 26, 2023Assignee: GRAPE KING BIO LTDInventors: Hsing-Chun Kuo, Chin-Chu Chen, Yen-Lien Chen, Shih-Wei Lin, Yen-Po Chen, Ci-Sian Wang, Yu-Hsin Hou, Yang-Tzu Shih, Ching-Wen Lin, Ya-Jyun Chen, Jia-Lin Jiang, You-Shan Tsai, Zi-He Wu
-
Patent number: 11751591Abstract: A strain of Oceanobacillus picturae and applications thereof are provided, which relate to technical fields of microorganism and food processing. A strain of halophilic bacteria was screened from the brine of Xiangyang Pickled Kohlrabi and was identified as the strain of Oceanobacillus picturae by morphology, physical and chemical properties and 16S rRNA sequence. The strain is able to significantly increase the varieties and contents of volatile substances, and decrease the contents of pungent substances in pickled vegetables. The strain of Oceanobacillus picturae can improve the taste and the flavor of the pickled vegetables.Type: GrantFiled: September 5, 2020Date of Patent: September 12, 2023Assignee: Hunzhong Agricultural UniversityInventors: Xiaoyun Xu, Ting Wu, Jie Song, Siyi Pan
-
Patent number: 11746368Abstract: The present invention provides a Lactococcus lactis subsp. lactis A32, derived product and use thereof, the present invention falls in the technical field of microorganisms. In the present invention, the Lactococcus lactis subsp. lactis A32 is obtainable by compound mutation on the basis of the original strain L. lactis lxl. Experiments showed that, compared with nisin titre of the original strain L. lactis lxl, the Lactococcus lactis subsp. lactis A32 has high nisin yield, and the nisin titre has been improved for 3˜4 times (over 5066.58 IU/mL); in the meanwhile, the growth curve of the Lactococcus lactis subsp. lactis A32 is slightly longer than the original strain L. lactis lxl and biomass peaks of them are basically consistent. The present invention has laid a foundation for large scale production of nisin.Type: GrantFiled: September 2, 2022Date of Patent: September 5, 2023Assignee: QILU UNIVERSITY OF TECHNOLOGYInventors: Deqiang Zhu, Xinli Liu, Yujie Lian, Leshan Han, Shuo Peng
-
Patent number: 11744866Abstract: Methods of preventing and treating COVID-19 infection by administering probiotics. The probiotics can be administered via the following methods: fecal transplant, suppository, or orally. The probiotic contains one or more of the following microorganisms: Bifidobacterium, Clostridium, Veillonella, Ruminococcus, and Sutterella.Type: GrantFiled: March 12, 2021Date of Patent: September 5, 2023Inventor: Sabine Hazan
-
Patent number: 11725227Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.Type: GrantFiled: August 1, 2018Date of Patent: August 15, 2023Assignee: Essenlix CorporationInventors: Stephen Y. Chou, Wei Ding
-
Patent number: 11713473Abstract: The present disclosure discloses a process for accelerating, increasing, and stabilizing production of biogas with a high methane content in systems for biodigestion of organic waste. The process comprises: a) obtaining from an anaerobic biodigester (3) a fraction of organic waste equal in weight to K times the weight of the daily organic waste load of the anaerobic biodigester (3), wherein the parameter K is a numeric value selected between 10?3 and 10?1, sending the fraction to one or more acceleration devices (4), retaining the fraction in the one or more acceleration devices (4) until a final concentration (Cf) of the methanogenic bacteria in the fraction is equal to M times an initial concentration (Ci), wherein the parameter M is a numeric value selected between 103 and 108; b) as soon as said final concentration (Cf) is obtained in the fraction, directing said fraction from the acceleration device (4) back to the anaerobic biodigester (3); and c) successively repeating steps a) and b).Type: GrantFiled: July 1, 2021Date of Patent: August 1, 2023Assignees: G-Meta Consultoria, Participaçôes e Serviços LTDA, Bio-Tronic Energy Co. LLCInventor: Luciano Pesce
-
Patent number: 11696932Abstract: Provided herein are recombinant microorganisms that express a subject polypeptide. Microorganisms can comprise an expression construct comprising a flagellin promoter operatively linked with a heterologous nucleotide sequence encoding the subject polypeptide. The flagellin promoter sequence can comprise a genetic modification that reduces CsrA inhibition of translation. Microorganisms also can comprise a genetic modification that reduces FlgM inhibition of SigD initiation of transcription. The target polypeptide can be an aldehyde dehydrogenase. Such microorganisms are useful in the treatment of alcohol hangover.Type: GrantFiled: September 13, 2018Date of Patent: July 11, 2023Assignee: ZBiotics CompanyInventor: Zachary Abbott
-
Patent number: 11685888Abstract: A method for producing a product related to the specified technology includes adjusting the concentration of cells in a culture vessel to a value of from 3×107 cells/ml to 3×108 cells/ml; in a case in which the average diameter of single cells in the culture vessel is designated as A, adjusting the number proportion of cells having a single cell diameter of 1.4×A or greater in the culture vessel to 5% or less, and adjusting the number proportion of cells having a single cell diameter in the range of A±A/7 to 50% or more.Type: GrantFiled: March 3, 2020Date of Patent: June 27, 2023Assignee: FUJIFILM CorporationInventors: Shinichi Nakai, Naoto Takahashi
-
Patent number: 11684644Abstract: Disclosed is a composition for promoting absorption of a poorly water-soluble phytochemical which can significantly improve the intake of a phytochemical into a body, especially a migration speed and/or a migration amount of the phytochemical into a blood. A polysaccharide-containing lactic acid bacterial product, which is produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1251, can significantly enhance the intake of a phytochemical into a body, especially a migration speed and/or a migration amount of the phytochemical into a blood. Thus, the composition for promoting absorption of a phytochemical according to the present invention includes, as an active ingredient, the polysaccharide-containing lactic acid bacterial product. Furthermore, the composition for promoting absorption of a phytochemical is useful as a food additive composition.Type: GrantFiled: August 7, 2019Date of Patent: June 27, 2023Assignee: MEIJI CO., LTD.Inventors: Masashi Morifuji, Masami Kitade, Satomi Ichikawa
-
Patent number: 11666614Abstract: Isolates strains of gastrointestinal bacteria from wolves are provided for use as probiotics. In some embodiments, the isolated strains are for use as probiotics in canine subjects such as domestic dogs. In some embodiments, the isolated strains may be used to treat or prevent intestinal dysbiosis in the subject. Also provided are compositions comprising at least one isolated strain of wolf probiotic bacteria and related methods for making same.Type: GrantFiled: August 21, 2019Date of Patent: June 6, 2023Assignee: CanBiocin Inc.Inventors: Qixing Ou, John F. Burlet
-
Patent number: 11660322Abstract: An oral composition comprising at least one probiotic bacteria selected from the genera: Lactobacillus, Bifidobacterium, and Bacillus, and ferric pyrophosphate.Type: GrantFiled: June 9, 2016Date of Patent: May 30, 2023Assignee: Societe des Produits Nestle S.A.Inventors: Sophie Moille, Irma Silva Zolezzi, Edwin Alberto Habeych Narvaez, Nicola Galaffu, Bertrand Bourqui, Sara Colombo Mottaz
-
Patent number: 11648282Abstract: Disclosed is a composition for promoting absorption of a poorly water-soluble phytochemical which can significantly improve the intake of a phytochemical into a body, especially a migration speed and/or a migration amount of the phytochemical into a blood. A polysaccharide-containing lactic acid bacterial product, which is produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1251, can significantly enhance the intake of a phytochemical into a body, especially a migration speed and/or a migration amount of the phytochemical into a blood. Thus, the composition for promoting absorption of a phytochemical according to the present invention includes, as an active ingredient, the polysaccharide-containing lactic acid bacterial product. Furthermore, the composition for promoting absorption of a phytochemical is useful as a food additive composition.Type: GrantFiled: August 7, 2019Date of Patent: May 16, 2023Assignee: MEIJI CO., LTD.Inventors: Masashi Morifuji, Masami Kitade, Satomi Ichikawa
-
Patent number: 11617770Abstract: The present disclosure relates to the isolation, identification and characterization of novel sporeforming probiotic strain(s) with NSPase (Non-Starch Polysaccharides-active hydrolases) activity isolated from fish gut microbiota, methods and uses thereof. The sporeforming probiotic strain(s) with NSPase activity now disclosed are able of producing carbohydrate-active enzymes (CAZymes) that hydrolyse non-starch polysaccharides (NSPs) and accesses their potential as probiotics (PRO) for use in particular in aquafeeds.Type: GrantFiled: October 24, 2019Date of Patent: April 4, 2023Assignees: CIIMAR—CENTRO INTERDISCIPLINAR DE INVESTIGAÇÄO MARINHA E AMBIENTAL, UNIVERSIDADE DO PORTOInventors: Claudia Alexandra Dos Reis Serra, Paula Cristina Enes Oliveira Da Silva, Aires Oliva Teles, Fernando Tavares
-
Patent number: 11590181Abstract: Use of a sugar selected from lactose, fructose and raffinose, for increasing serpin expression in Bifidobacterium longum strain CNCM I-2618.Type: GrantFiled: December 27, 2018Date of Patent: February 28, 2023Assignee: Societe des Produits Nestle S.A.Inventors: Stephane Duboux, Gabriela Bergonzelli Degonda, Annick Mercenier, Muzi Tangyu
-
Patent number: 11578304Abstract: Provided is a method of culturing one or more microorganisms. The method includes culturing one or more microorganisms in a medium comprising crude glycerol at a first concentration level, feeding to the media an additional amount of crude glycerol, once the first concentration of glycerol is reduced to a first threshold level, at a concentration sufficient to achieve the first concentration level, monitoring the crude glycerol concentration until the first concentration level of the crude glycerol is reduced to the first threshold level. The steps may be repeated until a desired microorganism cell density is achieved.Type: GrantFiled: March 24, 2016Date of Patent: February 14, 2023Assignee: Mara Renewables CorporationInventors: Laura Purdue, Michael Milway, Kevin Berryman, Mercia Valentine, Zhiyong Sun, Roberto E. Armenta
-
Patent number: 11572578Abstract: The present invention relates to a reagent kit for detecting biofilm in test tissue, the reagent kit comprising: (a) a pretreatment liquid comprising at least one surfactant selected, from the group consisting of nonionic surfactants, amphoteric surfactants, and cationic surfactants, (b) a staining liquid comprising a dye, and (c) a decolorizing liquid comprising at least one surfactant selected from the group consisting of nonionic surfactants, amphoteric surfactants, and cationic surfactants; wherein after a membrane is brought into contact with the test tissue and released from contact, the pretreatment liquid (a), the staining liquid (b), and the decolorizing liquid (c) are brought into contact with the contact surface of the membrane in this order.Type: GrantFiled: July 31, 2019Date of Patent: February 7, 2023Assignee: SARAYA CO., LTD.Inventors: Yoriko Kato, Yuka Oda, Emiko Kawamukai, Yoshihiko Hirata
-
Patent number: 11571387Abstract: The invention relates to a process for the preparation of dry lyophilized powdered formulations of probiotic bacteria for monogastric animal (for example poultry birds) using a combination of different polymers through the process of encapsulation. The resulting lyophilized powders of probiotic bacteria are having increased viability during animal feed processing, storage and upon transfer to the monogastric animal's digestive system.Type: GrantFiled: March 5, 2018Date of Patent: February 7, 2023Assignee: PRAJ INDUSTRIES LIMITEDInventors: Aamod Anil Natu, Sharad Krishnachandra Laldas, Shaileshkumar Dhondiram Sawale, Shilpa Sachin Pradhan, Aarohi Atul Kulkarni
-
Patent number: 11564955Abstract: The present invention relates to a composition comprising as an active ingredient a strain having excellent ability to produce formic acid for preventing or treating obesity or metabolic syndromes caused by obesity; and to a food composition and a health functional food each comprising the active ingredient. The strain having excellent ability to produce formic acid according to the present invention not only has effects of reducing body weight and inhibiting fat accumulation in organs, but also has activity to effectively lower blood triglyceride and cholesterol levels, and therefore, the composition comprising the strain as an active ingredient can be favorably used as a composition capable of preventing/alleviating or treating obesity or metabolic syndromes caused by obesity. Therefore, the strain having excellent ability to produce formic acid according to the present invention can be favorably used as a material for a medical product or health food.Type: GrantFiled: November 21, 2017Date of Patent: January 31, 2023Assignee: KOREA FOOD RESEARCH INSTITUTEInventors: Myung Ki Lee, Sang Dong Lim, Sung Hun Yi, Yong Sun Cho, Young Do Nam, Jin Ju Bae
-
Patent number: 11564956Abstract: The present invention relates to the technical field of microbes, in particular to a Lactobacillus plantarum which can significantly inhibit the occurrence of colorectal cancer, and its use thereof. The Lactobacillus plantarum strain CCFM164 has a deposit number CGMCC No. 14520, which has a good tolerance to gastric acid and bile salts, significantly alleviate the level of colorectal inflammation in colorectal cancer model mice, and can reduce the number of tumors in the colon and rectum of the model mice by regulating the Notch1, Notch2 signaling pathway and the expression of VEGFR2 molecule in colorectal tissue. In addition, the Lactobacillus plantarum CCFM164 can also improve the intestinal flora population and short-chain fatty acid levels in the intestine. The Lactobacillus plantarum CCFM164 is used to prepare a fermented food for the inhibition of the occurrence of colorectal cancer with wild applications.Type: GrantFiled: July 19, 2018Date of Patent: January 31, 2023Assignee: Jiangnan UniversityInventors: Wei Chen, Gang Wang, Eryin Wang, Jianxin Zhao, Hao Zhang
-
Patent number: 11542560Abstract: The present disclosure provides for characterization of normal flora and identifying biomarkers in the gut of healthy, neurotypical subjects. Aspect of the disclosure provide for the characterization of the gut microbiome in ADS subjects, characterized by reduced richness and significant loss of the ‘Prevotella-like enterotype’ compared to neurotypical subjects. The relative abundance of genera Prevotella, Coprococcus, Prevotellaceae and Veillonellaceae are significantly lower in autistic children than in neurotypical children. Further, Prevotella, is one of the three main classifiers for the human enterotypes, along with Bacteriodes and Ruminococcus. These three core genera are among main contributors in the principle component analysis. ‘Prevotella-like enterotype’ was absent in the autistic group, while neurotypical samples showed an even distribution among the three enterotypes.Type: GrantFiled: August 30, 2018Date of Patent: January 3, 2023Assignee: Board of Regents on Behalf of Arizona State UniversityInventors: Rosa Krajmalnik-Brown, Dae-Wook Kang, Jin Gyoon Park, Joshua Labaer, Zehra Ilhan