Abstract: A console assembly for a vehicle includes a unitary main body. The unitary main body includes a first side wall, a second side wall, and a top finish portion that extends between the first and second side walls. The top finish portion defines at least one of a shifter receiving aperture and a cup holder opening. A cross bracket is coupled to the first and second side walls and extends between the first and second side walls of the unitary main body.

Abstract: A process of modifying a passage in a component is provided. The process includes inserting a first material into the passage; blocking at least one end of the passage; inserting an elongated member into the passage through the first material; heat treating the passage, the first material, and the elongated member to form a solid interior in component; and machining through the solid interior to form a modified passage in the component.

Abstract: A method for generating a trajectory for a vehicle based on an abstract space of control parameters associated with the vehicle may include applying a machine learning model to determine an abstract space representation of the trajectory, which includes a sequence of control parameters associated with the vehicle. For instance, application of the machine learning model may include performing a search of the abstract space parameterized by control parameters that include derivatives of the position of the vehicle. Examples of control parameters include velocity, acceleration, jerk, and snap. A physical space representation of the trajectory may be determined by at least mapping the sequence of control parameters to a sequence of positions for the vehicle. A motion of the vehicle may be controlled based at least on the physical space representation of the trajectory. Related systems and computer program products are also provided.

Abstract: A first nest structure and a second nest structure are brought into alignment. When the alignment of the first nest structure and second nest structure is obtained, the operation of at least one vacuum pump is controlled such that a bearing element is released from the first nest structure and secured in the second nest structure. Movement of the bearing element from the first nest structure to the second nest structure occurs without slippage resulting in preservation of a common frame of reference used when the bearing element is in the first nest structure and the second nest structure.

Abstract: Immunogen enhancers for admixture with an antigen of interest are described herein. The enhancers generally comprise a steroid acid and/or a steroid acid-peptide conjugate in an amount sufficient to improve or modify the adaptive immune response to antigens admixed therewith. In embodiments, the steroid acid may be a bile acid and the peptide may comprise one or more functional domains, such as a nuclear localization signal, which may facilitate antigen-presentation and/or antigen cross-presentation, thereby triggering improved cellular immunity, or improved cellular and humoral immunity, against the antigen.

Abstract: Methods that may be used for the manufacture of the chemical compound (R)-Reticuline and synthesis precursors thereof. Compositions useful for the synthesis (R)-Reticuline and synthesis precursors are also provided.

Abstract: There is described a multimode interferometric device and a method for performing multimode interferometry. The device comprises at least one single-mode transmission input connectable to a light source for receiving single-mode light, a multimode output for emitting multimode light and collecting reflected multimode light, at least one photonic lantern operatively connected between the at least one single-mode transmission input and the multimode output and designed for converting the single-mode light into multimode light and converting the reflected multimode light into single-mode light, at least one single-mode reference input for generating at least one interference pattern between the reflected single-mode light and at least one single-mode reference signal, and at least one single-mode output connectable to a photodetector for detecting the at least one interference pattern.

Abstract: A carrier for an irradiated target includes a first portion and a second portion having inner walls. One or both of the first and second portions has a recess extending inwardly from the inner wall thereof to receive the irradiated target. The first and second portions are removably attachable in sealing engagement. The inner walls face each other and form a barrier around the recess upon the first and second portions being removably attached. A fastening system provided on one or both of the first and second portions maintains the first and second portions in sealing engagement. There is also disclosed a kit of the carrier and the irradiated target, a dissolution system for producing a solution from the irradiated target, and a corresponding method.

Abstract: Some embodiments described herein relate to a computer implemented method that includes performing a first work step associated with a first activity and with a first data product and performing a second work step associated with a second activity and associated with a second data product. A first chain of trust between the first work step and the second work step can be defined by defining a second manifest document that is associated with the second data product and that references a first manifest document associated with the first data product. An immutable data structure representing a second chain of trust independent of the first chain of trust can be defined by submitting the first manifest document and the second manifest document to a distributed ledger for validation.

Abstract: Disclosed herein are several embodiments of a negative pressure appliance and methods of using the same in the treatment of wounds. Some embodiments are directed to improved fluidic connectors or suction adapters for connecting to a wound site, for example using softer, kink-free conformable suction adapters.

Abstract: This invention pertains to mutant Lachnospiraceae bacterium ND2006 (Lb) Cas12a nucleic acids and proteins for use in CRISPR/Cas12a endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant LbCas12a protein, wherein the isolated mutant LbCas12a protein is active in a CRISPR/Cas12a endonuclease system. The invention also includes isolated nucleic acids encoding mutant LbCas12a proteins, ribonucleoprotein complexes and CRISPR/Cas12a endonuclease systems having mutant LbCas12a proteins.

Abstract: The disclosure provides Moloney murine leukemia virus (MMLV) reverse transcriptase (RTase) mutants. The disclosure as provides suitable amino acid positions in MMLV RTase for mutagenesis and methods and kits for using MMLV RTase mutants to synthesize cDNA from RNA templates.

Abstract: A method for designing an image filter, the method being executed by a machine learning algorithm (MLA), the method comprising: receiving unfiltered images, a desirable visual task and an undesirable visual task; for each unfiltered image, receiving a first label indicative of whether the desirable visual task is accomplishable and a second label indicative of whether the undesirable visual task is accomplishable; filtering the unfiltered image using a virtual filter model representative of the image filter; using the filtered images, training the MLA to perform the desirable visual task and prevent the undesirable visual task to be performed; using test images, determining a first efficiency for the MLA to perform the desirable task and a second efficiency for the MLA to prevent the undesirable task; adjusting a parameter of the virtual filter model based on the first and second efficiencies; and outputting the adjusted parameter.

Abstract: Apparatuses, such as shower door frame kits, for installing sliding shower door assemblies are provided. The apparatuses enable secure and convenient installation of the sliding shower door assemblies, while keeping water that may escape a shower area to a minimum. The apparatuses of the present disclosure also provide for efficient installation of the sliding shower door assemblies that can be completed with a single tool and/or in a single step. The apparatuses for installing sliding shower door assemblies may include one or more of a shower door header, a wall jamb, a shower header retainer, a shower door catcher, a roller assembly, a corner bracket, and a shower threshold.

Abstract: Method and system for determining the real-time flow into a wastewater pump station using analog level sensing technologies. An Accurate Level Generator mechanism supplies an accurate mean value out of multiple readings for each level used to calculate the volume between levels. Two consecutive levels are used to calculate the volume between them using an Accurate Flow Calculator and the time it took to get from one level to the other. A Real Time Inflow Calculator adds results regarding the pumps in operation and overflow events, which are ways for the water to exit the pumping station. At a water level approaching where the pumps start or stop, or when abnormal events occur, a Predictive Abnormal Event Adjuster replaces the highly probable abnormal Real Time Inflow Result by a more stable and possible value, which is the last one calculated plus its variation over time.

Abstract: A method of de-mosaicing pixel data from an image processor includes generating a pixel block that includes a plurality of image pixels. The method also includes determining a first image gradient between a first set of pixels of the pixel block and a second image gradient between a second set of pixels of the pixel block. The method also includes determining a first adaptive threshold value based on intensity of a third set of pixels of the pixel block. The pixels of the third set of pixels are adjacent to one another. The method also includes filtering the pixel block in a vertical, horizontal, or neutral direction based on the first and second image gradients and the first adaptive threshold value utilizing a plurality of FIR filters to generate a plurality of component images.

Abstract: An Ethernet switch and a switch microcontroller or CPU are integrated onto a system-on-a-chip (SoC). The Ethernet switch remains independently operating at full speed even though the remainder of the SoC is being reset or is otherwise nonoperational. The Ethernet switch is on a separated power and clock domain from the remainder of the integrated SoC. A warm reset signal is trapped by control microcontroller (MCU) to allow the switch CPU to isolate the Ethernet switch and save state. When the Ethernet switch is isolated and operating independently, the warm reset request is provided to the other entities on the integrated SoC. When warm reset is completed, the state is restored and the various DMA and flow settings redeveloped in the integrated SoC to allow return to normal operating condition.