Abstract: Provided herein are dosing and combination therapies with a CD39 antibody, a PD-1 antibody, and FOLFOX or CAPDX in gastric cancer.

Abstract: Rather than waiting on a squelch to detect the difference in the state from steady to floating, this disclosure suggests using the time from when a reference clock is turned on to begin the process to exit the hibernation state. The reference clock is turned off while a data storage device is in the hibernation state to save power. Once the host is ready for the device to exit the hibernation state, the reference clock is turned on. The reference clock is monitored for the change. Once the reference clock is on, the data storage device returns to a steady state. In the ready state, the data storage device has a shortened ready time. Once the ready time is complete, the data storage device may now exit the hibernation state without waiting on squelch detection or a hibernation exit request from the host.

Abstract: Systems and methods that allow optical detection of nanoparticles according to size and interaction with specific antibodies. Using abiological sample combined with fluorescent dyes and fluorescently labeled antibodies, implementations of the disclosed system allow for detection of >100 particles having diameters as low as 100 nm in under 10 minutes. The detection mechanisms combine confocal detection of particles in microfluidic flow devices. Concentrating the sample using hydrodynamic focusing allows detection of particles having concentrations as low as 104 particles per mL of the sample. These capabilities allow for the detection, identification, and quantitation of viruses from bodily fluids such as saliva, where biologically relevant virus concentrations of potentially infected subjects are within the range of 103-107 particles/mL.

Abstract: Caps and other luer taper medical devices having a volume displacing protrusion are described. The volume displacing protrusion can extend in an axial direction away from an end wall inside the female hub and be configured to create a seal that can be substantially airtight with a distal end of a syringe that is engaged with the cap or other luer taper medical device. The volume displacing protrusion of the cap or other luer taper medical device can create a seal with a distal end of a syringe before an outside surface of the syringe tip creates a seal with the luer taper of the female hub.

Abstract: Embodiments of a showerhead are described herein. In some embodiments, a showerhead assembly includes: a first gas delivery portion having a first body, a first inlet, and a plurality of first tubes extending from the first body and defining a first plenum, wherein each tube of the plurality of first tubes includes a plurality of first holes; and a second gas delivery portion having a second body, a second inlet, and a plurality of second tubes extending from the second body and defining a second plenum fluidly independent from the first plenum, wherein each tube of the plurality of second tubes includes a plurality of second holes, and wherein the plurality of first tubes are disposed in an alternating pattern with the plurality of second tubes across a width of the showerhead assembly and a heat sink disposed between the plurality of first tubes and the plurality of second tubes.

Abstract: Intelligent ticketing and data offload planning is provided. A data center receives a ticket request from a vehicle requesting to perform a data upload of vehicle data over a communications network. An optimizer is utilized to generate a ticket, the ticket specifying a time and a location for the vehicle to perform the data upload. The ticket is received from the vehicle. The ticket is validated to ensure that the vehicle should still perform the data upload. The vehicle is indicated to perform the data upload over the communications network responsive to the optimizer confirming the data upload to proceed. The data upload is stored to a storage of the data center.

Abstract: A robotic system for preparing layered foodstuffs comprises a conveyor subsystem having an intelligent working member that travels through an equipped loading and unloading area, within the operating region of which are equipment for storing and supplying bases and, adjacent thereto, a food primary processing subsystem. The storage and supply equipment is configured in the form of an automated refrigeration unit having a rotating manipulator mechanism for the bases, which is combined with an integrated device for picking up and supplying the bases to an active surface of the working member for the subsequent culinary processing of said bases. The combined working of the different systems is controlled by an intelligent device connected to a central server, providing the high-speed, faultless and precise application of ingredients.

Abstract: The disclosure is generally directed to systems and methods for a mobile device including transmitting a request by the mobile device for a route that considers transportation modalities and route conditions, the request including location data of the mobile device, receiving a recommended route, the recommended route based on low energy hardware based classification of conditions associated with a plurality of available routes, and receiving a recommended transport modality vehicle and a list of known vehicle identifiers associated with the location data. Low energy wireless signals are received by the mobile device with low energy hardware based classifiers from a mobility vehicle including dedicated hardware including a being a field programmable gate array (FPGA) or an application specific integrated circuit (ASIC) and/or hardware supporting a spiking neural network (SNN), the hardware receiving camera and microphone inputs.

Abstract: A computer-implemented method for virtual space insertion is provided. The computer-implemented method includes receiving first and second user inputs from users regarding user information and regarding a virtual space targeted for entry by each of the users, respectively, obtaining spatial and occupancy information of the virtual space, determining insertion point requirements for the entry of each of the users into the virtual space from the first user inputs, generating a self-similar geometric insertion point pattern compatible with the insertion point requirements to a first threshold and with the spatial and occupancy information to a second threshold and mapping an insertion point for the entry of each of the users into the virtual space to the self-similar geometric insertion point pattern.

Abstract: The present disclosure relates to recombinant RNA molecules encoding an oncolytic virus genome. The present disclosure further relates to the encapsulation of the recombinant RNA molecules and the use of the recombinant RNA molecules and/or particles for the treatment and prevention of cancer.

Abstract: Transportation-based service share systems and methods are disclosed herein. An example method can include receiving a request from a service provider to reserve a ridehail vehicle for a ridehail having a time frame, the request specifying a service provided by the service provider; determining the ridehail vehicle for the service provider based on the service; and dispatching the ridehail vehicle, the service provider rendering the service during the ridehail.

Abstract: A blood flow stimulator may help encourage blood flow in a limb of a patient. The blood flow stimulator may include a housing configured for sealing about the limb of the patient. The housing may include a sealable volume, and the sealable volume may receive the limb of the patient. The blood flow stimulator may include a seal, and the seal may be coupled with the housing. The seal may engage with at least a portion of the limb, for instance to segregate the sealable volume from a surrounding environment of the blood flow stimulator. The blood flow stimulator may include a conduit extending through the housing. The conduit mat help provide access to the sealable volume, for instance from the surrounding environment. In some examples, an adjustable stent is utilized to enhance blood flow within vasculature of a patient. A stent operator may change a size of the stent.

Abstract: A computer-implemented method for matching unstructured text to ontology entities in a clinical ontology is described. The method includes receiving one or more clinical notes associated with a patient; for each of the one or more clinical notes: extracting, using a neural network, one or more text spans from unstructured text in each clinical note, each of the one or more text spans identifying a respective input phrase in the unstructured text; for each of the one or more text spans, matching, using a text matcher, the text span with a respective output ontology entity from an ontology, the respective output ontology entity relating to a clinical condition of the patient; and outputting data defining the one or more text spans and the respective output ontology entity for each of the one or more text spans.

Abstract: One or more indicators provide an indication of the energy source of power for one or more vehicles. The indicators may be positioned on a vehicle and/or on other structures such as parking garages, tunnels, and entrance gates. The indicators may be visual and/or acoustic. On a vehicle the indicators are positioned to most likely be intact during and after an accident and provide a predetermined indication that identifies an energy source that provides power for the vehicle.

Abstract: A method of controlling a drive motor for a powered ankle exoskeleton is disclosed. The method includes modeling motor drive current as a linear function of desired torque and ankle angular velocity, and then controlling motor current as a function of measured torque and determined ankle angular velocity.

Abstract: Methods, apparatus, systems, and articles of manufacture to extend brake life cycle are disclosed herein. An example apparatus disclosed herein includes machine readable instructions and processor circuitry to at least one of instantiate or execute the machine readable instructions to activate a brake motor of a brake of a vehicle to cause contact between a brake pad of the brake and a rotor of the brake, compare a power output of the brake motor of the brake to a threshold, and determine a material degradation level of the brake pad based on the comparison of the power output to the threshold.

Abstract: Disclosed below are representative embodiments of methods, apparatus, and systems for managing, monitoring, controlling, and/or classifying assets in an information technology (“IT”) environment. Certain embodiments leverage bath services oriented architecture concepts and event mechanisms to create a platform with which additional controls can easily integrate.

Abstract: Systems, methods, and apparatuses for authenticating requests to access one or more accounts over a network using authenticity evaluations of two or more automated decision engines are discussed. A login request for access to a user account may be submitted to multiple decision engines that each apply different rulesets for authenticating the login request, and output an evaluation of the authenticity of the login request. Based on evaluations from multiple automated decision engines, the login request may be allowed to proceed to validation of user identity and, if user identity is validated, access to the user account may be authorized. Based on the evaluations, the login attempt may also be rejected. One or more additional challenge question may be returned to the computing device used to request account access, and the login request allowed to proceed to validation of identity if the response to the challenge question is deemed acceptable.

Abstract: A method for controlling target sound playback. A display screen of a control device is configured to display a target sound user setting for controlling target sound playback, wherein the target sound user setting controls a stored target sound level parameter that is stored within memory of the control device. A target sound sequence is generated in accordance with the user setting. A speaker is driven with the target sound sequence. Other aspects are also described and claimed.

Abstract: A catheter may include a withdrawal lumen wall extending around a withdrawal lumen. The withdrawal lumen may have a withdrawal lumen profile. The catheter may include an infusion lumen wall coupled with the withdrawal lumen wall. The infusion lumen wall may extend around an infusion lumen. The infusion lumen may have an infusion lumen profile smaller than the withdrawal lumen profile. A flexible septum may extend between the withdrawal lumen and the infusion lumen. The flexible septum may isolate the withdrawal lumen from the infusion lumen. In another example, a blood filtration system may monitor blood flow velocity within vasculature. The blood filtration system may guide operation of a blood pump or a filtrate bump based on the blood flow velocity within the vasculature.