Abstract: The soporific activity of cis-9,10-octadecenoamide and other soporific fatty acid primary amides is neutralized by hydrolysis in the presence of fatty-acid amide hydrolase (FAAH). Hydrolysis of cis-9,10-octadecenoamide by FAAH leads to the formation of oleic acid, a compound without soporific activity. FAAH has be isolated and the gene encoding FAAH has been cloned, sequenced, and used to express recombinant FAAH. Inhibitors of FAAH are disclosed to block the hydrolase activity.

Abstract: An apparatus includes an electromagnetic radiation source, a reflector about the source having an aperture and a curved filter at least partially across the aperture.

Abstract: A method and apparatus emits light from multiple light sources and combines the etendue of the light sources such that the etendue is substantially uniformly distributed over an area.

Abstract: Provided is a method for obtaining a position of an object. A slide which carries at least one object and has reticle marks arranged at positions which form substantially a right angle, is positioned in a slide holder of a first imaging system. A first coordinate space of the imaging system is defined, and coordinates of the reticle marks in the first coordinate space are designated. A second coordinate space of a second imaging system is defined, and the coordinates of the reticle marks in the second coordinate space is designated. Using the designated coordinates of the reticle marks of the first coordinate space, the coordinate conversion parameters are computed. Thereafter, coordinates of at least one object in the first coordinate space are designated, and the first coordinate space coordinates of the object are converted into unique coordinates in a second coordinate space, using the coordinate conversion parameters.

Abstract: A method of testing a coating on a reflector having a first focal point includes placing a mirror at the first focal point of the reflector and angled to orient with an area on the coating. Electromagnetic (EM) radiation is directed to the mirror which then directs the EM radiation on the area. The EM radiation which is reflected from the coating is collected onto a sensor disposed at a second focal point. The intensity of the EM radiation collected on the sensor is detected.

Abstract: An optical relay includes a first lens, a lens module, and a second lens. The first lens is configured to receive modulated light from a first spatial light modulator. The first lens is configured to refract the modulated light into the lens module. The lens module is configured to collimate and focus the modulated light into the second lens. The second lens is configured to refract the modulated light onto a second spatial light modulator.

Abstract: A unified user interface is described that allows a user to search, browse, and launch items from the same user interface. For example, a single text input box may be provided that allows the user to perform all these functions by typing in a portion of an item name or an entire item name. The various functions may be selectively performed depending upon the text inputted by the user into the text input box. For example, where the text appears to be the beginning of an item name, then those items matching the input text will dynamically appear as the user types. Or, where the text appears to be the beginning of a file path, then items in that file path may be presented. In addition, advanced items such as system files may be suppressed so that inexperienced users do not accidentally stumble across these items.

Abstract: A compact imaging spectrometer with an immersive diffraction grating that compensates optical distortions. The imaging spectrometer comprises an entrance slit for transmitting light, means for receiving the light and directing the light, an immersion grating, and a detector array. The entrance slit, the means for receiving the light, the immersion grating, and the detector array are positioned wherein the entrance slit transmits light to the means for receiving the light and the means for receiving the light directs the light to the immersion grating and the immersion grating receives the light and directs the light to the means for receiving the light, and the means for receiving the light directs the light to the detector array.

Abstract: Preferred embodiments of a purge gas port, laser beam attenuating input window, and laser shutter constitute subsystems of a UV laser optical system in which a laser beam is completely enclosed to reduce contamination of the optical system components. Purge gas is injected through multiple locations in a beam tube assembly to ensure that the optical component surfaces sensitive to contamination are in the flow path of the purge gas. The input window functions as a fixed level attenuator to limit photopolymerization of airborne molecules and particles. Periodically rotating optical elements asymmetrically in their holders reduces burn damage to the optics.

Abstract: A projection system comprising an illumination relay, a coupling lens, a modulation device, and a projection lens is provided. The illumination relay is configured to provide an illumination beam to the coupling lens along an illumination path having a first optical axis. The coupling lens is configured to direct the illumination beam onto the modulation device. The modulation device is configured to modulate the illumination beam to form an imaging beam and reflect the imaging beam into the coupling lens. The coupling lens is configured to direct the imaging beam into the projection lens along a projection path having a first optical axis such that the second optical axis is substantially parallel with the first optical axis.

Abstract: The present invention relates to a method for isolating from the immunological gene repertoire a gene coding for a receptor having the ability to bind a preselected ligand. Receptors produced by the gene isolated by the method, particularly catalytic receptors, are also contemplated.

Abstract: An optical relay comprising a first mirror and a second mirror is provided. The first mirror is configured to receive modulated light from a first spatial light modulator and reflect the modulated light onto the second mirror. The second mirror is configured to reflect the modulated light onto the first mirror, and the first mirror is configured to reflect the modulated light onto a second spatial light modulator.

Abstract: Filamentous phage comprising a matrix of cpVIII proteins encapsulating a genome encoding first and second polypeptides of an antogenously assembling receptor, such as an antibody, and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a filamentous phage coat protein membrane anchor domain fused to at least one of the polypeptides.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. A representative function includes a determination whether the receiving participant is a paid subscriber.

Abstract: The invention describes the display of exogenous polypeptides on filamentous phage using a fusion between the exogenous polypeptide and phage pVII or pIX proteins. In particular, phage particles and phagemid vectors are described for expression and display of heterodimeric proteins such as antibody Fv heterodimers in combinatorial libraries, and uses thereof.

Abstract: The present invention describes methods for producing antibody libraries, and particularly for increasing antibody library diversity by inducing mutagenesis within the CDR regions of immunoglobulin heavy or light chains that are displayed on the surface of filamentous phage particles comprising the library. The invention also describes oligonucleotides useful for increasing the library diversity, and universal light chains useful in the library production methods.

Abstract: A compact imaging spectrometer comprises an entrance slit, a catadioptric lens with a mirrored surface, a grating, and a detector array. The entrance slit directs light to the mirrored surface of the catadioptric lens; the mirrored surface reflects the light back through the lens to the grating. The grating receives the light from the catadioptric lens and diffracts the light to the lens away from the mirrored surface. The lens transmits the light and focuses it onto the detector array.

Abstract: A compact imaging spectrometer with an immersive diffraction grating that compensates optical distortions. The imaging spectrometer comprises an entrance slit for transmitting light, a system for receiving the light and directing the light, an immersion grating, and a detector array. The entrance slit, the system for receiving the light, the immersion grating, and the detector array are positioned wherein the entrance slit transmits light to the system for receiving the light and the system for receiving the light directs the light to the immersion grating and the immersion grating receives the light and directs the light through an optical element to the detector array.

Abstract: An imaging spectrometer comprising an entrance slit for directing light, a lens that receives said light and reflects said light, a grating that defracts said light back onto said lens which focuses said light, and a detector array that receives said focused light. In one embodiment the grating has rulings immersed into a germanium surface.

Abstract: A compact imaging spectrometer comprising an entrance slit, an anamorphic mirror, a grating, and a detector array. The entrance slit directs light to the anamorphic mirror. The anamorphic mirror receives the light and directs the light to the grating. The grating receives the light from the anamorphic mirror and defracts the light back onto the anamorphic mirror. The anamorphic mirror focuses the light onto a detector array.