Patents by Inventor A. M. McDonald

A. M. McDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
    Publication number: 20200109140
    Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.
    Type: Application
    Filed: June 26, 2019
    Publication date: April 9, 2020
    Inventors: Upender VELAPARTHI, Louis S. Chupak, Chetan Padmakar Darne, Min Ding, Robert G. Gentles, Yazhong Huang, Manjunatha Narayana Rao Kamble, Scott W. Martin, Raju Mannoori, Ivar M. McDonald, Richard E. Olson, Hasibur Rahaman, Prasada Rao Jalagam, Saumya Roy, Gopikishan Tonukunuru, Sivasudar Velaiah, Jayakumar Sankara Warrier, Xiaofan Zheng, John S. Tokarski, Bireshwar Dasgupta, Kotha Rathnakar Reddy, Thiruvenkadam Raja
  • AUTONOMOUS OR REMOTE-CONTROLLED VEHICLE PLATFORM FOR PLANTING
    Publication number: 20200107495
    Abstract: In one embodiment, a vehicle platform comprises a central body that can support one or more implement configurations, such as sprayer booms, or planting row units. A plurality of adjustable legs extends downward from the central body. Each adjustable leg has a corresponding leg actuator to adjust a respective vertical height of each adjustable leg. Each adjustable leg supports the central body.
    Type: Application
    Filed: December 5, 2019
    Publication date: April 9, 2020
    Applicant: Deere & Company
    Inventors: Richard J. Connell, Michael M. Miller, Austin N. Thompson, Brandon M. McDonald, Shayne C. Rich
  • SYSTEM AND METHOD FOR METERING AMMONIA ANHYDROUS
    Publication number: 20200100424
    Abstract: A distributed metering system and method for metering liquid anhydrous ammonia is disclosed. The distributed metering system can comprise a plurality of applicator devices coupled to a plurality of metering units, and an electronic control unit coupled to the plurality of metering units. The electronic control unit is configured to control an application rate of a crop input material supplied from the plurality of metering units by adjusting an operating parameter of a component of each of the plurality of metering units when the application rate exceeds or falls below a predetermined threshold.
    Type: Application
    Filed: October 1, 2018
    Publication date: April 2, 2020
    Inventors: Scott M. Buse, Brandon M. McDonald
  • High efficiency electrochemical desalination system that incorporates participating electrodes
    Patent number: 10604426
    Abstract: The present invention discloses an apparatus and a method to desalinate aqueous solution. The apparatus disclosed herein comprises at least two electrodes and at least one ion selective membrane in continuous contact with the aqueous solution that is contained in the internal space created by connecting a top manifold and a bottom manifold of the apparatus. The ion selective membrane(s) are arranged in such a manner as to enable reversing the flow of the charged particles by direct or indirect means. The electrodes in this apparatus may be made of material that reversibly reacts with chlorides in water.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: March 31, 2020
    Assignee: Magna Imperio Systems Corp.
    Inventors: Michael James Connor, Jr., Brian M. McDonald, Grant R. Page
  • METHODS AND APPARATUS FOR EFFICIENT MATERIAL APPLICATION
    Publication number: 20200077576
    Abstract: Methods, apparatus, systems and articles of manufacture are disclosed for efficient material application. An example landscape treatment apparatus includes a main carrier tank to store a solvent, a concentrate tank to store a solute, and a first mix tank to receive the solvent and the solute as a first mixture. The example apparatus further includes a second mix tank to receive the solvent and the solute as a second mixture, where the first mix tank is to receive the solvent and the solute in alternation with the second mix tank receiving the solvent and the solute. The example apparatus also includes a boom to apply the first mixture and the second mixture to a landscape via a plurality of nozzles, where the boom is to apply the first mixture and the second mixture in alternation.
    Type: Application
    Filed: September 12, 2018
    Publication date: March 12, 2020
    Inventors: Terence D. Pickett, Travis J. Davis, Brandon M. McDonald
  • Network accessible file server
    Patent number: 10558622
    Abstract: A cloud-based write-once object store is configured to store inode-based data exported to the store from an enterprise file system. For each version of data (e.g., a file) exported to the store, there is a version of the inode corresponding to that data. As versions of the data are exported to the cloud, the system creates multiple versions of the inode. The set of inode versions corresponding to the versions of the file have a pointer associated therewith that specifies the latest version of the data associated with the inode. The inode versions in the set share the same pointer. The inode versions represent a revision history for the inode. For each inode version corresponding to a version of the data, information is received and stored in a new portion of the object store. The inode version for a file version comprises a list of data chunks for the file.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: February 11, 2020
    Assignee: Nasuni Corporation
    Inventors: David M. Shaw, Matthew M. McDonald, Russell A. Neufeld, Christopher S. Lacasse
  • Autonomous or remote-controlled vehicle platform for planting
    Patent number: 10542666
    Abstract: In one embodiment, a vehicle platform comprises a central body that can support one or more implement configurations, such as sprayer booms, or planting row units. A plurality of adjustable legs extends downward from the central body. Each adjustable leg has a corresponding leg actuator to adjust a respective vertical height of each adjustable leg. Each adjustable leg supports the central body. Planting row units are supported by or suspended from the central body.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: January 28, 2020
    Assignee: Deere & Company
    Inventors: Richard J. Connell, Michael M. Miller, Austin N. Thompson, Brandon M. McDonald, Shayne C. Rich
  • ION SELECTIVE MEMBRANE WITH IONOPHORES
    Publication number: 20200001251
    Abstract: The present disclosure is directed an ion exchange membrane that has an increased affinity for a specific ionic species. The ion exchange membranes disclosed herein include ionophores that can increase ion-selectivity. These ion exchange membranes can be incorporated to various ion-exchange systems or devices that can selectively separate ions of value.
    Type: Application
    Filed: June 27, 2019
    Publication date: January 2, 2020
    Applicant: Magna Imperio Systems Corp.
    Inventors: Ethan DEMETER, Michael James CONNOR, JR., Brian M. MCDONALD
  • METHOD OF MITIGATING COMPACTION AND A COMPACTION MITIGATION SYSTEM
    Publication number: 20200000006
    Abstract: In accordance with an example embodiment, a compaction mitigation system for a work area and a method of mitigating compaction in a work area are provided. The method includes determining a compaction map of the work area having compaction data associated with a plurality of reference points, passing a work tool through the work area at the plurality of reference points, and adjusting the work tool at the plurality of reference points based on the compaction data.
    Type: Application
    Filed: June 29, 2018
    Publication date: January 2, 2020
    Inventors: BRANDON M. MCDONALD, JACOB D. MAYER, THOMAS G. MUELLER, BENJAMIN M. SMITH, RYAN JENSEN
  • 3D PRINTED SPACERS FOR ION-EXCHANGE DEVICE
    Publication number: 20190388843
    Abstract: The present disclosure is directed ion-exchange systems and devices that include composite ion-exchange membranes having 3D printed spacers on them. These 3D printed spacers can drastically reduce the total intermembrane spacing within the system/device while maintaining a reliable sealing surface around the exterior border of the membrane. By adding the spacers directly to the membrane using additive manufacturing, the amount of material used can be reduced without adversely impacting the manufacturability of the composite membrane as well as allow for complex spacer geometries that can reduce the restrictions to flow resulting in less pressure drop associated with the flow in the active area of the membranes.
    Type: Application
    Filed: June 24, 2019
    Publication date: December 26, 2019
    Applicant: Magna Imperio Systems Corp.
    Inventors: Ethan Demeter, Michael James Connor, JR., Chad Unrau, Brian M. McDonald
  • Vehicle Door Latch Security Tether
    Publication number: 20190390490
    Abstract: A vehicle that includes a door, handle, shaft, and a latch assembly is provided. The latch assembly is coupled to the door to selectively secure the door. The latch assembly includes a security tether configured to prevent the shaft from moving the pawl when the lock lever is located in the locked condition.
    Type: Application
    Filed: September 6, 2019
    Publication date: December 26, 2019
    Applicant: Truck Accessories Group, LLC
    Inventors: Eugene A. Dylewski, II, Ernest M. McDonald, II
  • Ground-engaging implement with lateral position adjustment
    Patent number: 10492360
    Abstract: A row frame is coupled to the rear member. A first opener is configured to open the soil; the first opener is supported by or from a first support extending downward from the frame member. A first outlet is configured to dispense or apply a nutrient strip. A laterally movable carrier is associated with the row frame. The carrier supports the first opener and the first outlet. A second outlet can dispense or plant seed, wherein the first outlet and the second outlet have a lateral separation that is dynamically adjustable during the simultaneous application of seed and the nutrient strip.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: December 3, 2019
    Assignee: DEERE & COMPANY
    Inventors: Richard J. Connell, Brandon M. McDonald, Larry L. Hendrickson
  • ANTIPROLIFERATIVE COMPOUNDS AND CONJUGATES MADE THEREFROM
    Publication number: 20190358339
    Abstract: A compound capable of inhibiting cell proliferation, having a structure according to formula (I) wherein the variables in formula (I) are as defined in the specification. Such compounds are useful as anti-cancer agents, especially in antibody-drug conjugates.
    Type: Application
    Filed: August 6, 2019
    Publication date: November 28, 2019
    Inventors: Ivar M. McDonald, Prasanna Sivaprakasam, Christiana I. Iwuagwu, Kevin M. Peese, Heng Cheng, Naidu S. Chowdari, Sanjeev Gangwar
  • Ground-engaging implement with lateral position adjustment
    Patent number: 10485154
    Abstract: A data processor determines whether a draft force on the implement is unbalanced based on an error between the observed implement angle and a target implement heading exceeding a threshold deviation. The data processor is adapted to generate a control signal to compensate for the imbalance in the draft force by adjusting the first lateral position via the first actuator, or by adjusting the second lateral position via the second actuator, the first actuator and the second actuator being positioned on opposite lateral sides of the implement.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: November 26, 2019
    Assignee: DEERE & COMPANY
    Inventors: Richard J. Connell, Brandon M. McDonald, Larry L. Hendrickson
  • Ground-engaging implement with lateral position adjustment
    Patent number: 10485161
    Abstract: A first rear member is spaced apart from the front member and positioned generally parallel to the front member. A first pair of first pivotable arms are generally parallel to each other. The first pair of first pivotable arms are rotatably connected to the front member at two front pivot points. The first pair of first pivotable arms are rotatably connected to the rear member at two rear pivot points. At least one first opener (e.g., nutrient knife or projecting, ground-engaging member) extends downward from or with respect to the first rear member.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: November 26, 2019
    Assignee: DEERE & COMPANY
    Inventors: Richard J. Connell, Brandon M. McDonald, Larry L. Hendrickson
  • NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS
    Publication number: 20190322694
    Abstract: The present invention relates to novel phosphorous (V) (P(V)) reagents, methods for preparing thereof, and methods for preparing organophosphorous (V) compounds by using the novel reagents.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 24, 2019
    Inventors: Michael Anthony SCHMIDT, Bin ZHENG, Kyle KNOUSE, Justine deGRUYTER, Martin D. EASTGATE, Phil BARAN, William R. EWING, Richard E. OLSON, Ivar M. McDONALD
  • INTEGRATED STRONTIUM-RUBIDIUM RADIOISOTOPE INFUSION SYSTEMS
    Publication number: 20190307949
    Abstract: Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer may include pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system and/or injection parameters for quality control, and/or to perform purges of the system, and/or to facilitate diagnostic imaging.
    Type: Application
    Filed: May 24, 2019
    Publication date: October 10, 2019
    Inventors: Stephen E. Hidem, Aaron M. Fontaine, Janet L. Gelbach, Patrick M. McDonald, Kathryn M. Hunter, Rolf E. Swenson, Julius P. Zodda
  • ALKYLAMINE FUNCTIONALIZED METAL-ORGANIC FRAMEWORKS FOR COMPOSITE GAS SEPARATIONS
    Publication number: 20190291074
    Abstract: Functionalized metal-organic framework adsorbents with ligands containing basic nitrogen groups such as alkylamines and alkyldiamines appended to the metal centers and method of isolating carbon dioxide from a stream of combined gases and carbon dioxide partial pressures below approximately 1 and 1000 mbar. The adsorption material has an isosteric heat of carbon dioxide adsorption of greater than ?60 kJ/mol at zero coverage using a dual-site Langmuir model.
    Type: Application
    Filed: November 27, 2018
    Publication date: September 26, 2019
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jeffrey R. Long, Thomas M. McDonald, Deanna M. D'Alessandro
  • CAMK2D ANTISENSE OLIGONUCLEOTIDES AND USES THEREOF
    Publication number: 20190275148
    Abstract: The present disclosure relates to antisense oligonucleotides, which target CAMK2D mRNA in a cell, leading to reduced expression of CAMK2D protein. Reduction of CAMK2D protein expression is beneficial for the treatment of certain medical disorders, e.g., cardiovascular-related diseases or disorders.
    Type: Application
    Filed: February 21, 2019
    Publication date: September 12, 2019
    Inventors: Richard E. Olson, Brian R. Anderson, Peter Hagedorn, Marianne Lerbech Jensen, Ivar M. McDonald, Stephen E. Mercer
  • Vehicle door latch security tether
    Patent number: 10407953
    Abstract: A vehicle that includes a door, handle, shaft, and a latch assembly is provided. The latch assembly is coupled to the door to selectively secure the door. The latch assembly includes a security tether configured to prevent the shaft from moving the pawl when the lock lever is located in the locked condition.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: September 10, 2019
    Assignee: Truck Accessories Group, LLC
    Inventors: Eugene A. Dylewski, II, Ernest M. McDonald, II