Abstract: In the present invention, inventors provide compelling evidence showing that PCOS neuroendocrine reproductive and metabolic dysfunctions are transmitted in PAMH mice for at least three generations. Inventors employed genome-wide methylated DNA immunoprecipitation (MeDIP) analysis to characterize methylated genes in ovaries from control and PAMH mice of the third generation, the first unexposed transgenerational offspring, together with transcriptome analysis in these tissues. Inventors identified many genes with altered transcriptome expression in ovarian tissues of PCOS-animals and they show that several key molecules associated to the PCOS phenotype are epigenetically regulated through DNA hypomethylation. Inventors report that several differentially methylated signatures found in the ovaries of PCOS-like mice are also present in blood samples from women with PCOS and from daughters born to women with PCOS.

Abstract: A method of managing filesystem elements between a user device and a network connected to the user device comprising: receiving a request related to a filesystem element operation over the network; performing the filesystem element operation; updating a local metadata file based on the operation; downloading an encrypted network metadata file including data of the filesystem on the network from the network to the user device. The method comprises decrypting the encrypted network metadata file on the user device with a network encryption key; and provided the network metadata stored in the network is newer than the updated local metadata file, merging the network metadata file stored in the network with the updated local metadata file to update the local metadata file. The method comprises encrypting the updated local metadata file on the user device with the network encryption key; and uploading the encrypted updated metadata file to the network.

Abstract: In an approach for automatic vertical partitioning of fact tables in a distributed query engine a processor analyzes a sample end-user workload of queries to extract filter predicates associated with each of multiple fact tables relating to a big data store. A processor, for each fact table, and for each column in the fact table to which a filter predicate is applied and where coarsification is required, generates a candidate partitioning expression incorporating an adjustment to a coarsification function based on a data distribution of values in the column. A processor scores the candidate partitioning expressions for each fact table based on cost data relating to the sample end-user workload and selects one or more candidate partitioning expressions to optimize partitioning of each fact table with each partition data being placed in a separate directory in a distributed file system.

Abstract: A retractor member is configured for insertion through a channel of an access member and for moving soft tissue at a treatment site that is accessible through the channel. The retractor includes a body having a proximal end and a distal end and spaced from each other along a longitudinal direction. The distal end defines a retractor blade and the body defines a first surface and a second surface opposite each other along a transverse direction substantially perpendicular to the longitudinal direction. The retractor includes an attachment device configured to selectively attach the body to a portion of the access member such that the body is extendable through the working channel while the body is attached to the portion of the access member.

Abstract: An apparatus and method for identifying, at a serving base station, a clear channel assessment operation status for at least one neighbouring cell; and for transmitting an indication of the clear channel assessment operation status for the at least one neighbouring cell to a served user equipment.

Abstract: An induction cooktop includes a cooktop surface, a plurality of power delivery coils in an array beneath the cooktop surface, a cooking article detector, a light source directed toward the cooktop surface, and a controller. The controller receives a signal from the cooking article detector including size and position information for at least one detected cooking article on the cooktop surface and determines that a detected position of the detected cooking article does not correlate with a preferred position of the cooking article with respect to at least one of the plurality of power delivery coils. The controller then presents an indication, via the light source, of the preferred position of the detected cooking article on at least one of the detected cooking article and the cooktop surface.

Abstract: A monochromator apparatus for an optical spectrum analyzer may include a diffraction grating, a rotatable oblique prism reflector element with a non-right-angle apex angle, and a mirror. An input optical beam received from an input component may be diffracted by the grating element and reflected by a reflector element, where the reflector element may include a rotatable oblique prism with an apex angle that is different from a right angle. A mirror may reflect the reflected diffracted optical beam back to the reflector element and the grating element. An output optical beam from the grating element may be provided via an output element to a detection element for high resolution optical measurement. The oblique prism reflector element may reduce or eliminate a Littrow ghost effect or secondary ghost effects caused by the grating element.

Abstract: Methods and systems are provided for automating steps of a workflow within a medical image processing system. In one example, a method for a medical image processing system comprises extracting expressions from description fields of a set of Digital Imaging and Communications in Medicine (DICOM) files of a medical imaging exam that match reference terms of an ontology; mapping the matching reference terms of the ontology to one or more lexicon entries of a radiology lexicon; selecting a suitable software application to review the medical imaging exam based on the one or more lexicon entries; opening the suitable software application on a device of the medical image processing system; and displaying the medical imaging exam on a display of the device within the suitable software application. The ontology includes reference terms generated from DICOM sources, vocabulary from other relevant lexicons, ontologies, reference databases, and human experts.

Abstract: Multiple techniques for testing a UE by a Test Equipment (TE) are disclosed. A TE configures with a procedure of performance testing of data transmission to be performed while the UE is in an inactive state. The TE performs the performance testing, wherein the procedure includes at least one of: triggering the data transmission while the UE is in the inactive state; transmitting one or more test data packages; controlling time that the UE starts to transmit, while in the inactive state, payload corresponding to the test data package(s); verifying whether or not conditions for the data transmission are met; or determining whether or not the UE passed the performance testing, based on a result of the verification of whether or not conditions for the data transmission are met. The UE performs the data transmission and can send measurement results. There are multiple conditions that can be tested.

Abstract: The invention relates to a process for depolymerizing a polyester feedstock comprising PET, said process comprising, prior to the step of depolymerization by glycolysis and to the step of purification of the depolymerization effluent, an improved step of conditioning the feedstock in which the polyester feedstock is conditioned in terms of temperature and pressure and then mixed with a diol effluent in a static or dynamic mixer in order in particular to substantially reduce the viscosity of the feedstock.

Abstract: The invention relates to a test arrangement for testing breakage and mechanical properties of rock particles. Test arrangement comprises a support (1, 2) and two counter-rotatable crushing rolls (3, 3?) supported on the support (1, 2) and a drive arrangement (M1, M2) for rotating the crushing rolls (3, 3?). Crushing rolls (3, 3?) are facing each other and defining therebetween an input gap (G) for the rock particles, said rolls being arranged to crush rock particles (RP) to smaller daughter particles (DP). Test arrangement comprises a force measurement arrangement (7, 7?) for determining the compressive strength of rock particles (RP). Force measurement arrangement (7, 7?) being coupled to a processor (PR) comprised by the test arrangement. The processor (PR) being arranged to calculate the breakage force applied to each rock particle (RP) over time.

Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).

Abstract: A computer-implemented method, system and computer program product for optimally performing stress testing against big data management systems. A set of random test queries is generated and compiled to determine the data points of the features (e.g., table type being queried) of the set of random test queries. A distance (e.g., Mahalanobis distance) is then measured between the data points of the features and the mean of a distribution of data points corresponding to each same feature of an extracted feature set. Each random test query whose distance exceeds a threshold distance is then ranked. The ranked random test queries are then executed in order of rank. Those executed random test queries which resulted in an error (e.g., system failure) are added to a log, which is used to identify those queries to perform a stress test against the big data management system.

Abstract: An appliance having a user interface with a first controller module, and at least one leak detector. The at least one leak detector having a housing with a second controller module communicatively coupled to the first controller module, and a power source communicatively coupled to the second controller module. The at least one leak detector further having at least one sensor communicatively coupled to the second controller module. The second controller module being configured to receive a status from at least one of either the power source or the at least one sensor.

Abstract: Methods and systems are disclosed for providing automated assistance to a user of a software application on a computing device. In one example, a method comprises, during operation of a software application running on a computing device by a user, the user prompted to select an option of a plurality of options of the software application at a step of the operation: predicting, via an automated assistance service running on the computing device, one or more preferred options of a plurality of options of the software application based on administrative guidelines, best practices, and previous selections made by the user, peers of the user, and other local users; displaying the one or more preferred options on a display device of the software application; receiving a selection of a most suitable option of the one or more preferred options from the user; and applying the selected option in the software application.

Abstract: A first Flight Control system configuration, and the method to obtain such first configuration, has controllers of effector actuation able to receive commands directly from at least three Flight Control Computers (FCCs). A second Flight Control system configuration, and the method to obtain such second configuration, has retransmitters (RTX) that receive commands from the three FCCs and then retransmit to the controllers of effector actuation. A third Flight Control system configuration, and the method to obtain such third configuration, is a hybrid configuration.

Abstract: A refrigerator water dispenser includes a shelf having a lower surface. A water dispenser tube is disposed adjacent to the shelf for dispensing water into a container. An actuator support is operably coupled to the lower surface of the shelf. A load cell is disposed on the actuator support, wherein the load cell sends a signal in response to movement by the actuator support. A controller is operably coupled to the load cell, wherein the controller activates a water dispensing sequence to dispense water via the water dispenser tube in response to the signal from the load cell.

Abstract: Camera position indication systems and methods are disclosed herein for conveying a camera's position to a user and/or adjusting a camera view display to match a user's perspective during a surgical procedure. In one embodiment, an example method can include receiving an output view from a camera placed within a channel of an access device to view a surgical site within a patient, receiving an input of camera position from a user, and showing on a display the output view from the camera and an indication of camera position based on the input of camera position.

Abstract: A retractor member is configured for insertion through a channel of an access member and for moving soft tissue at a treatment site that is accessible through the channel. The retractor includes a body having a proximal end and a distal end and spaced from each other along a longitudinal direction. The distal end defines a retractor blade and the body defines a first surface and a second surface opposite each other along a transverse direction substantially perpendicular to the longitudinal direction. The retractor includes an attachment device configured to selectively attach the body to a portion of the access member such that the body is extendable through the working channel while the body is attached to the portion of the access member.

Abstract: A refrigerating appliance includes a lighting system having a lighting device arranged to operatively illuminate the interior of the refrigerating appliance based on a predetermined condition. The lighting device includes a light source and an electrochromic device. The light source is arranged to selectively provide a first light to the electrochromic device. The electrochromic device is selectively operable to emit a second light within the interior. The color, color temperature, and diffusion of the second light can be indicative of a status of the refrigerating appliance and can be selectable by a user.