Abstract: A composition and method is disclosed for fluoridating teeth using a two component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which a carrageenan gum having major kappa and lambda forms as the primary thickening agent and the abrasive is a silica providing an acid pH when slurried with water, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and the abrasive and carrageenan gum in an aqueous vehicle. The first and second dentifrice compounds are maintained separate from the other until mixed for application to teeth.

Abstract: A dual component dentifrice composition in which the first component is a stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable compound in which calcium ion is absent and the second component is a semi-solid, extrudable dentifrice composition containing a dicalcium phosphate abrasive having a magnesium ion content less than about 0.5% by weight wherein increased fluoride uptake is achieved when the components are mixed upon application to dental tissue.

Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.

Abstract: A method is disclosed for inhibiting bone resorption, concomitant with the overproduction of PTH associated with hyperparathyroidism or secondary hyperparathyroidism, by providing a azacycloalkane-2,2-diphosphonic compound.

Abstract: Stable oral compositions containing an antibacterial casein glycomacropeptide, an anionic surfactant, and a hydrolyzed protein stabilizer, which stabilizes the casein glycomacropeptide in the presence of the anionic surfactant against inactivation without substantially reducing its antibacterial properties.

Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methy cellosolve and ethyl cellosolve: a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.

Abstract: A method is disclosed for fluoridating teeth using a two component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which xanthan gum is the major thickening agent and glycerin, sorbitol or mixtures thereof is the humectant, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and an abrasive in an aqueous vehicle containing xanthan gum as the major thickener and glycerin, sorbitol or mixtures thereof as the humectant. The first and second dentifrice compounds are maintained separate from the other until mixed for application to teeth.

Abstract: An oral composition comprising in an orally acceptable vehicle, an effective antiplaque amount of an halogenated diphenyl ether or phenolic antibacterial compound, and an amount of an mixed anionic/nonionic surfactant system at weight ratios of about 14:1 to 9:1 which ratios are effective to increase the uptake of the antibacterial compound to dental tissue so as to enhance the therapeutic efficacy of the administered antibacterial compound.

Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.

Abstract: Oral compositions comprising the combination of an effective surface tension reducing amount of an amphoteric surfactant and an effective antimicrobial amount of a blend of phenolic agents is disclosed. These compositions are indicated in the management or control of dental plaque.

Abstract: A two component whitening dentifrice composition is disclosed which comprises a first component containing a peroxygen compound such as hydrogen peroxide and a second dentifrice component containing a manganese coordination complex compound such as manganese gluconate, which activates the peroxygen compound and accelerates the release of active oxygen for rapid whitening action, the first and second components being maintained separate from the other until dispensed for application to teeth.

Abstract: The invention provides an antibacterial oral composition containing an antibacterial compound such as Triclosan and a monoalkyl phosphate compound whereby the uptake and retention of the antibacterial compound on dental tissue is substantially increased due to the presence of the monoalkyl phosphate compound.

Abstract: An oral gel composition suitable for application to teeth and gums, particularly of people having dental implants. The gel composition contains an aqueous orally acceptable gel vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxyl-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces. The gel composition is extruded from a syringe into contact with a dental implant area thereby causing the composition to be delivered to and retained on the dental implant area.

Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methy cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.

Abstract: A oral composition which inhibits plaque formation and reduces gingivitis and caries comprising a substantially water insoluble noncationic antimicrobial agent, such as triclosan and an acid reducing agent, such as xylitol. The composition is a dentifrice containing a siliceous polishing agent.

Abstract: Oral composition containing an effective amount of N-methylpyrrolidone alone or in combination with a noncationic antibacterial agent such as Triclosan for topical application for the prevention of plaque, gingivitis and/or caries.

Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.

Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.

Abstract: An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula.

Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.