Patents by Inventor Abdul Gaffar

Abdul Gaffar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial antiplaque oral composition
    Patent number: 5037635
    Abstract: An oral composition such as a dentifrice or mouthwash, containing an aqueous phase of water and as solubilizing agent propylene glycol, dipropylene glycol, methyl cellosolve, ethyl cellosolve, olive oil, castor oil, amyl acetate, ethyl acetate, glyceryl tristrearate or benzyl benzoate mixed with at least one glycerine and sorbitol, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (triclosan), and a synthetic anionic linear polymeric polycarboxylate having a molecular weight of about 1,000 to about 1,000,000.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: August 6, 1991
    Assignee: Colate-Palmolive Company
    Inventors: Nuran Nabi, Abdul Gaffar
  • Inactivation of bacterial endotoxins using peroxy-diphosphate compoounds
    Patent number: 5034383
    Abstract: Bacterial endotoxins are inhibited by a non-toxic, water-soluble, pharmaceutically acceptable peroxydiphosphate compound in contact with bacterial endotoxin.
    Type: Grant
    Filed: March 13, 1989
    Date of Patent: July 23, 1991
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Edward J. Coleman
  • Antiplaque antibacterial oral composition
    Patent number: 5032386
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: August 25, 1989
    Date of Patent: July 16, 1991
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Inhibition of parathyroid hormone secretion
    Patent number: 5028439
    Abstract: Parathyroid Hormone, when excessively synthesized, induces pathologic bone resorption and demineralization and results in hypocalcemia which produces toxic effects in soft tissues. Non-toxic water-soluble pharmaceutically acceptable compound derivative of peroxydiphosphoric acid, administered orally or systemically, inhibits parathyroid hormone induced bone resorption in vitro and in vivo in warm blooded animals.
    Type: Grant
    Filed: January 9, 1989
    Date of Patent: July 2, 1991
    Assignee: Colgate Palmolive Company
    Inventor: Abdul Gaffar
  • Anticalculus oral composition
    Patent number: 5017362
    Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, to inhibit enzymatic hydrolysis of said polyphosphate salt in saliva, a combination of a fluoride ion-providing source and a synthetic linear polymeric polycarboxylate.
    Type: Grant
    Filed: December 8, 1989
    Date of Patent: May 21, 1991
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka
  • Oligosaccharide inhibition of Streptococcus pyogenes adhesion
    Patent number: 5002759
    Abstract: A method of, and oral composition for, inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these cells with an oligosaccharide having at least one fucose moiety or a galactose moiety which is free of digalactose and N-acetylneuraminyl lactose.
    Type: Grant
    Filed: July 25, 1989
    Date of Patent: March 26, 1991
    Assignees: Colgate-Palmolive Company, Forsyth Dental Center
    Inventors: Abdul Gaffar, Ronald J. Gibbons, Stanislawa Tylewksa
  • Inhibition of tumor development
    Patent number: 4975423
    Abstract: Non-toxic water-soluble pharmaceutically acceptable compound derivative of peroxydiphosphoric acid when administered orally or systemically supplements inhibition of malignant myeloma carcinoma tumor development of tumor cells in vitro and actual tumor development in vivo in warm blooded animals.
    Type: Grant
    Filed: May 3, 1989
    Date of Patent: December 4, 1990
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Anticalculus oral composition
    Patent number: 4931273
    Abstract: An oral dentifrice composition such as a toothpaste, dental gel, toothpowder, dental tablet or lozenge containing as anticalculus agent about 4.3% to about 7% of alkali metal pyrophosphates comprising at least 4.3% of tetrapotassium pyrophosphate alone or admixed with up to 2.7% of tetrasodium pyrophoshpate, and as inhibitors against enzymatic hydrolysis of such agent in saliva, a fluoride and preferably up to about 3% of a synthetic anionic polymeric polycarboxylate, and use of such composition in a program of oral hygiene and/or for inhibiting dental calculus.
    Type: Grant
    Filed: November 16, 1989
    Date of Patent: June 5, 1990
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka, Robert J. Ferlauto, Jr., Rosemarie M. Crisafulli
  • Anticalculus oral composition
    Patent number: 4925654
    Abstract: An oral dentifrice composition such as a toothpaste, dental gel, toothpowder, dental tablet or lozenge containing as anticalculus agent about 4.3% to about 7% of alkali metal pyrophosphates comprising at least 4.3% of tetrapotassium pyrophosphate alone or admixed with up to 2.7% of tetrasodium pyrophosphate, and as inhibitors against enzymatic hydrolysis of such agent in saliva, a fluoride and preferably up to about 3% of a synthetic anionic polymeric polycarboxylate, and use of such composition in a program of oral hygiene and/or for inhibiting dental calculus.
    Type: Grant
    Filed: February 8, 1989
    Date of Patent: May 15, 1990
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka, Robert J. Ferlauto, Jr., Rosemarie M. Crisafulli
  • Anticalculus oral composition
    Patent number: 4921693
    Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, to inhibit enzymatic hydrolysis of said polyphosphate salt in saliva, a combination of a fluoride ion-providing source and a synthetic linear polymeric polycarboxylate.
    Type: Grant
    Filed: February 8, 1989
    Date of Patent: May 1, 1990
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka
  • Anticalculus oral composition
    Patent number: 4921692
    Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, to inhibit enzymatic hydrolysis of said polyphosphate salt in saliva, a combination of a fluoride ion-providing source and a synthetic linear polymeric polycarboxylate.
    Type: Grant
    Filed: February 8, 1989
    Date of Patent: May 1, 1990
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka
  • Anticalculus oral composition
    Patent number: 4906456
    Abstract: An oral dentifrice composition such as a toothpaste, dental gel, toothpowder, dental tablet or lozenge containing as anticalculus agent about 4.3% to about 7% of alkali metal pyrophosphates comprising at least 4.3% of tetrapotassium pyrophosphate alone or admixed with up to 2.7% of tetrasodium pyrophosphate, and as inhibitors against enzymatic hydrolysis of such agent in saliva, a fluoride and preferably up to about 3% of a synthetic anionic polymeric polycarboxylate, and use of such composition in a program of oral hygiene and/or for inhibiting dental calculus.
    Type: Grant
    Filed: February 17, 1989
    Date of Patent: March 6, 1990
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka, Robert J. Ferlauto, Jr., Rosemarie M. Crisafulli
  • Antibacterial antiplaque oral composition
    Patent number: 4894220
    Abstract: An oral composition such as a dentifrice or mouthwash, containing an aqueous phase of water and as solubilizing agent propylene glycol, dipropylene glycol, methyl cellosolve, ethyl cellosolve, olive oil, castor oil, amyl acetate, ethyl acetate, glyceryl tristearate or benzyl benzoate mixed with at least one of glycerine and sorbitol, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxydiphenyl ether (triclosan), and a synthetic anionic linear polymeric polycarboxylate having a molecular weight of about 1,000 to about 1,000,000.
    Type: Grant
    Filed: December 29, 1988
    Date of Patent: January 16, 1990
    Assignee: Colgate-Palmolive Company
    Inventors: Nuran Nabi, Abdul Gaffar
  • Anticalculus oral composition
    Patent number: 4889712
    Abstract: In an anticalculus oral composition containing in an orally acceptable vehicle one or a mixture of water soluble linear molecularly dehydrated alkali metal or ammonium polyphosphate salts as essential anticalculus agent, an amount of a fluoride ion source sufficient to supply about 25 ppm to about 2,000 ppm of fluoride ions, and one or a mixture of water soluble alkali metal or ammonium synthetic anionic polymeric polycarboxlate salts, the improvement comprising employing in said composition a polyphosphate ion:polycarboxylate salt weight ratio ranging from about 0.3:1 to about 2.5:1.
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: December 26, 1989
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Shek-Hong H. Lau, John Afflito, Arline M. Nykvist
  • Anticalculus oral compositions
    Patent number: 4889713
    Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, to inhibit enzymatic hydrolysis of said polyphosphate salt in saliva, a combination of a fluoride ion-providing source and a synthetic linear polymeric polycarboxylate.
    Type: Grant
    Filed: February 8, 1989
    Date of Patent: December 26, 1989
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Thomas G. Polefka
  • Anticalculus oral composition
    Patent number: 4880619
    Abstract: Oral compositions such as mouthwashes and toothpastes, creams, gels and powders containing as anticalculus agent phosphonoformic acid or salt thereof and optionally also an F-providing anticaries compound, and method of using such compositions.
    Type: Grant
    Filed: May 2, 1986
    Date of Patent: November 14, 1989
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Anticalculus oral composition
    Patent number: 4869898
    Abstract: An oral composition such as toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, to inhibit enzymatic hydrolysis of said polyphosphate salt in saliva, a combination of a fluoride ion-providing source and a synthetic linear polymeric polycarboxylate.
    Type: Grant
    Filed: January 25, 1988
    Date of Patent: September 26, 1989
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Thomas G. Polefka
  • Device and composition for treatment of the gums
    Patent number: 4843099
    Abstract: Ibuprofen, pharmaceutically acceptable salt thereof or lower alkyl C.sub.1-6 ester thereof, in solution in periodontal gum device comprising elongated handle member terminating proximally in a flexible tip portion provided with an aperture for discharge of the solution which is effective to reduce gingival inflammation and swelling.
    Type: Grant
    Filed: July 20, 1987
    Date of Patent: June 27, 1989
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, John Afflitto
  • Anticalculus oral composition
    Patent number: 4826675
    Abstract: An Anticalculus Oral Composition, typically a mouthwash or dentifrice gel, containing compound having C-O-P bonds, such as phytic acid or an alkali metal (including ammonium) salt thereof as anticalculus agent, homogeneously distributed in a dentally acceptable oral vehicle. Also, present to inhibit enzymatic hydrolysis of the phytic compound and to promote caries reduction is an alkali metal fluoride.
    Type: Grant
    Filed: February 17, 1988
    Date of Patent: May 2, 1989
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Shek-Hong Lau, John Afflitto
  • Antiplaque/antigingivitis method using certain polyphosphonic acids
    Patent number: 4816245
    Abstract: A method of inhibiting human dental plaque and gingivitis involving regular application to the oral cavity of an oral composition containing an effective placque- and gingivitis-inhibiting amount of polyvinyl phosphonic acid or salt thereof having a number average molecular weight of about 4,000 to 9,100.
    Type: Grant
    Filed: September 25, 1987
    Date of Patent: March 28, 1989
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar