Abstract: There is described herein antagonists of ?4?7 integrin, and more particularly to cyclic peptide antagonists. Accordingly, there is described herein a compound of formula (I) wherein R1, R2, R3, R4, R5, R6, R7 and R8 are various substituents; stereocentres 1*, 2* and 3* are each independently selected from R and S; n is 1, 2, 3, or 4 and where n is 2-4, Z is an amino terminus of an amino acid; —C?O— adjacent L is the carboxy terminus of an amino acid; and L along with Z and —C?O— is a peptide.

Abstract: An automatically adjustable abrasive recycling system is provided. The abrasive recycling system includes one or more sensors configured to sense at least one characteristic of the abrasive recycling system, and slurry supply mechanism that operates, at least in part, based upon the sensed characteristic to control the operation of the abrasive recycling system. The abrasive recycling system further includes a substantially vertically arranged configuration of component parts. Methodology corresponding to the automatic operation of the abrasive recycling system is also provided.

Abstract: A diagnostics system comprising a controller for controlling operations of a mass flow controller. The controller is communicable coupled to at least one sensor and to a valve and tuned to control the valve based on a predetermined set point value and communication from the at least one sensor. The controller determines at least one predetermined value associated with a reverse flow of a fluid and either cause the controller to enter a hard fault or a safe state. The predetermined value of the flow is either a percentage of total flow or a percentage of total flow over a time period. The controller can log the date, time, and a device identifier in response to determining the at least one predetermined value. In addition, the diagnostics system can include a centralized controller configured to receive diagnostics data from a plurality of controllers and control operation of the controllers.

Abstract: A method for sensor provisioning in a wireless sensor network includes determining, at a gateway, that no neighboring gateway is present; in response to no neighboring gateway present, measuring signal strengths from a plurality of sensors; based on the measured signal strengths, identifying a sensor from the plurality of sensors to be paired with the gateway; and in response to identifying the sensor, pairing the gateway and the sensor to enable a secured connection between the gateway and the sensor.

Abstract: There is described herein antagonists of ?4?7 integrin, and more particularly cyclic peptide antagonists, such as compounds of formula (I).

Abstract: A drive shaft coupling is provided, such as a coupling used with a formula delivery appliance. The drive shaft coupling generally includes a drive gear and a driven gear, with one of the drive gear and driven gear having a biasing member to allow axial translation. The drive shaft coupling is generally configured to transfer rotation from the drive gear to the driven gear. In one aspect, the drive shaft coupling is capable of alignment and coupling of the drive gear and driven gear upon the radial sliding of the coupling from a non-engagement position to an engagement position.

Abstract: A door closer, including: an anchor assembly, including: a frame mounting plate which is fixable relative to a door frame; and an adjustor plate; and an actuator assembly for mounting within the thickness of a door leaf to move the door leaf between open and closed configurations relative to the door frame, the actuator assembly including an operating member coupled by a link to the adjustor plate and mounted for a range of movements between a fully retracted position, in which the anchor assembly is held adjacent the actuator assembly when the door leaf is in the closed configuration, and an extended position, in which the anchor assembly is in spaced relation to the actuator assembly when the door leaf is in the open configuration, the link being configured to extend from the adjustor plate along a first axis, wherein the frame mounting plate is provided with one or more slot(s), the or each slot being elongated along a second axis, the second axis being generally orthogonal to the first axis.

Abstract: A method for sensor provisioning in a wireless sensor network includes determining, at a gateway, that no neighboring gateway is present; in response to no neighboring gateway present, measuring signal strengths from a plurality of sensors; based on the measured signal strengths, identifying a sensor from the plurality of sensors to be paired with the gateway; and in response to identifying the sensor, pairing the gateway and the sensor to enable a secured connection between the gateway and the sensor.

Abstract: A surround view system for a machine is provided. The surround view system includes a plurality of image capturing devices generating image data of surroundings of the machine, and an object detection system for detecting an object in a target field of view of the machine and generating object position data corresponding to the object. The surround view system also includes an image processing system configured to generate an initial 3-dimensional composite surround view by projecting the image data on a virtual model corresponding to the machine. The virtual model has a 3-dimensional shape based on an initial calibration position data. The image processing system is also configured to modify the 3-dimensional shape of the virtual model based on the object position data, and generate an updated 3-dimensional composite surround view by projecting the image data on the virtual model having a modified 3-dimensional shape.

Abstract: A document processing system receives a body of an e-mail message from an extension in an e-mail system and parses it to identify items that are to be included in a document created within the document processing system. The document processing system creates a document and populates it with the items identified in the body of the e-mail message and returns the created document to the extension in the e-mail system for interaction by a user.

Abstract: A computer-implemented method of executing a policy-based operation on a shared computer infrastructure includes storing in a computer memory a dynamically extensible metadata system that is in communication with a processor that executes policy-based operations, where the dynamically extensible metadata system includes a data structure, a collection method, a policy processing method, and a policy condition. The collection method is then executed to collect data from a first computer resource in the shared computer infrastructure using a first data structure and from a second computer resource in the shared computer infrastructure using a second data structure, where the first data structure and the second data structure are different data structures. The collected data is then processed with the policy processing method to determine if the collected data meets the policy condition.

Abstract: A smart window/door opening-closing device that can easily be installed for use with an existing door or window or can be built-in by the door or window manufacturer, can be programmed to activate the opening or closing of the door or window either (a) remotely, (b) automatically by a pet and/or (c) automatically by a voice command, is easily disengaged when use is not desired, provides safety and security to prevent unwanted opening or closing of the door or window, and is integrated with a wireless communication network to enable smart and remote control of the window/door actuator.

Abstract: Techniques are described for allocation hardware and/or bandwidth resources of a viewer device between a live streaming media content playback of a video player and a concurrently provided live chat. For example, the bandwidth used by the live chat can be adjusted based on the playback of the video player.

Abstract: A formula delivery appliance generally includes a formula delivery head having features to mix, direct, and distribute formulation through nozzles to a desired location, such as the hair or scalp of a user. In this regard, the formula delivery head may include a plurality of nozzles configured to discharge the formulation at a desired flow rate. In some instances, the flow rate across the plurality of nozzles is controlled such that each nozzle has a flow rate within a specified percentage of the average flow rate across the plurality of nozzles.

Abstract: A formula delivery appliance can be used for treatment of the hair and scalp, such as an appliance used to color hair. The appliance may include a consumable assembly incorporating various components of the hair and scalp treatment appliance, a portion of which may be consumed and then replaced by a user. In this regard, the consumable assembly may include one or more formulation delivery packets, nozzles, manifold chambers, distribution protrusions, and the like. The hair treatment appliance may also include a rotatable coupling having a driven gear and a drive gear, where the driven gear may selectively engage the drive gear. In another aspect, the hair treatment appliance may also include a fluid container to retain a volume of formulation for delivery to the appliance.

Abstract: A drive shaft coupling is provided, such as a coupling used with a formula delivery appliance. The drive shaft coupling generally includes a drive gear and a driven gear, with one of the drive gear and driven gear having a biasing member to allow axial translation. The drive shaft coupling is generally configured to transfer rotation from the drive gear to the driven gear. In one aspect, the drive shaft coupling is capable of alignment and coupling of the drive gear and driven gear upon the radial sliding of the coupling from a non-engagement position to an engagement position.

Abstract: A formula delivery system can be used in conjunction with hair and scalp treatment appliances to supply a hair treatment formulation to the appliance. In one aspect, the formula delivery system delivers hair coloring formulation to the appliance. Formula delivery systems of the present disclosure generally include at least one fluid container configured to retain a volume of formulation for delivery of the formulation to a hair coloring appliance. In this regard, the formula delivery system may be configured to removably couple to an inlet member of the appliance that allows the appliance to draw the formulation from the fluid container for use within the appliance.

Abstract: There is described herein use of a compound of formula (I) below to make cyclic peptides.

Abstract: A beverage brewing product for brewing a sweetened beverage is disclosed which produces a sweetened beverage solution that can be mixed with a diluting liquid and which comprises at least one water permeable sieve and/or a dissolvable film packet wherein beverage material and granulated sweetener are contained. The beverage material and sweetener are brewed and dissolved during steeping in hot water to produce a sweetened beverage solution. The beverage solution, if concentrated, is then mixed with a proportioned amount of diluting liquid to make a consistently sweet beverage. This beverage brewing product may be used to produce a variety of consistently sweetened beverages, including tea, coffee, lemonade, and other sweetened beverages.

Abstract: A surround view system for a machine is provided. The surround view system includes a plurality of image capturing devices generating image data of surroundings of the machine, and an object detection system for detecting an object in a target field of view of the machine and generating object position data corresponding to the object. The surround view system also includes an image processing system configured to generate an initial 3-dimensional composite surround view by projecting the image data on a virtual model corresponding to the machine. The virtual model has a 3-dimensional shape based on an initial calibration position data. The image processing system is also configured to modify the 3-dimensional shape of the virtual model based on the object position data, and generate an updated 3-dimensional composite surround view by projecting the image data on the virtual model having a modified 3-dimensional shape.