Abstract: Polishing pads having discrete and selectively arranged regions of varying porosity within a continuous phase of polymer material are provided herein. In one embodiment a polishing pad features a plurality of polishing elements each comprising a polishing surface and sidewalls extending downwardly from the polishing surface to define a plurality of channels disposed between the polishing elements, wherein one or more of the polishing elements is formed of a continuous phase of polymer material having one or more first regions comprising a first porosity and a second region comprising a second porosity, wherein the second porosity is less than the first porosity.

Abstract: Provided herein are compounds of the Formula I: and pharmaceutically acceptable salts, solvates and polymorphs thereof, wherein L, X1, R1, R2, R3, R4, R5 and R6 are as defined herein, for the treatment of BRAF-associated diseases and disorders, including BRAF-associated tumors, including malignant and benign BRAF-associated tumors of the CNS and malignant extracranial BRAF-associated tumors.

Abstract: A method and system for analysis of a facility may include providing an emulation host system, first generating a golden circuit model on the emulation host system, first inserting a first hardware trojan model, first emulating operation of the golden circuit model, and second emulating operation of the first hardware trojan model. A facility may include a trojan instrument facility having a trojan detection instrument comparing logic circuit output against a threshold for detecting hardware trojan activity, and outputting alert data, and in relation to opening one of a plurality of scannable access points, a scannable register is inserted into an active scan chain with an associated instrument interface.

Abstract: A blade assembly for a food processing appliance includes a shaft and a base member in which one end of the shaft is journalled for rotation about its axis. First and second blade members are mounted to the shaft at respective axial locations and extend radially and in opposite directions from their respective locations on the shaft, with the blade member nearer the free end of the shaft being angled back along the shaft towards the base member and the other blade member angled forwardly along the shaft, towards the free end. The first blade member further has associated therewith a relatively short and blunt stub-like blade portion angled forwardly from the support location for the first blade member and extending beyond the free end of the shaft.