Abstract: This present disclosure described methods for a marketplace of interactive live streaming multimedia overlays. At least one method includes a user playing video games on a computer, using software to stream all or part of their computer session to one or more streaming services, said software retrieving images from a web-service, some or all of said images having been acquired through an online marketplace, said images being used to create a video overlay, and said overlay being combined with the video of the user's computer session prior being encoded for transmission to one or more streaming services.

Abstract: The present disclosure described methods and systems for multimedia tactile augmentation. At least one method includes identifying media content loaded on a first computer, locating instructions stored on a second computer (said instructions corresponding to the content), initiating playback of the content, and synchronizing the instructions with the content. Said method further includes parsing and converting the instructions into one or more electrical signals, driving one or more haptic feedback devices with the electrical signals in synchronization with the playback of the content, and presenting the content to the user. The haptic feedback devices provide physical stimulation to a user accessing the content.

Abstract: This present disclosure described methods for a marketplace of interactive live streaming multimedia overlays. At least one method includes a user playing video games on a computer, using software to stream all or part of their computer session to one or more streaming services, said software retrieving images from a web-service, some or all of said images having been acquired through an online marketplace, said images being used to create a video overlay, and said overlay being combined with the video of the user's computer session prior being encoded for transmission to one or more streaming services.

Abstract: The present disclosure relates to a trocar assembly with an integrated scope-cleaning structure. The trocar assembly may include a housing defining boundaries of a chamber with (a) a proximal opening configured to receive a distal end of a scope, and (b) a distal opening in fluid and mechanical communication with a trocar cannula. The trocar assembly may further include a cleaning element located at least partially between the proximal opening and the distal opening, where the cleaning element is movable with respect to the housing from at least a first setting where a first portion of the cleaning element may be in a first location and may form a first cleaning surface within the chamber, the first cleaning surface configured to remove debris from a distal end of the scope when the distal end of the scope contacts the first portion of the cleaning element.

Abstract: The present disclosure relates to a housing for a laparoscopic trocar assembly with an integrated scope-cleaning structure. The housing may include a shell forming a wall portion of a chamber and a cleaning element forming at least a portion of an internal surface of the chamber, the cleaning element configured to remove debris from a distal end of a scope upon contact between the cleaning element and the distal end of the scope. The cleaning element may be movable with respect to the shell of the housing in response to an input force upon the shell that moves a portion of the shell and a portion of the cleaning element between a default state and a displaced state.

Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.

Abstract: A media appliance for multimedia augmentation is described. The media appliance includes a processor and a memory storing an application. The media appliance being connectable to a display device to enable playback of content and one or more hardware devices to provide augmentation of the content. The media appliance synchronizes content playback with execution of instructions for the one or more hardware devices.

Abstract: Disclosed are PTHrP analogue formulations for transdermal delivery of a therapeutically effective amount of a PTHrP analogue, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.

Abstract: A storage caddy for a cleaning implement can include a holder configured to receive a wand or cleaning implement and a storage container having a lid connected to the storage container. The storage caddy can also include a tray for holding a first set of cleaning pads and a sleeve for holding a second set of cleaning pads. The first set of cleaning pads can be arranged in an upper portion of the storage container above the second set of cleaning pads, and the second set of cleaning pads can be located in a lower portion of the storage container. The wand or cleaning implement can be configured to receive one of the first set of cleaning pads from the tray or one of the second set of cleaning pads from the sleeve.

Abstract: The present disclosure relates to a trocar assembly with an integrated scope-cleaning structure. The trocar assembly may include a chamber with a proximal opening configured to receive a distal end of a scope. A cannula extend distally from the chamber and may be configured to extend distally into a patient body. The cannula may be further configured to receive the distal end of the scope such that the scope can be maneuvered through the cannula to a location within the patient body. The trocar assembly may include a cleaning element forming a surface within the chamber, where the surface of the cleaning element is configured to remove debris from at least one non-longitudinal, end-facing surface of the scope.

Abstract: A trocar assembly with an integrated scope-cleaning structure may have a proximal portion configured for accessibility by a user and a cannula extending distally from the proximal portion and configured to extend distally into a patient body, where the cannula is further configured to receive a distal end of a scope such that the scope can be maneuvered through the cannula to a location within the patient body. A cleaning element may be included, where the proximal portion includes a housing, where the cleaning element is substantially located within the housing.

Abstract: A scope includes a housing having a distal portion with a distal end. A lens is at the distal end. A cleaning element is operatively coupled to the distal portion of the housing, wherein the cleaning element is movable between a first position and a second position contacting the distal end.

Abstract: A trocar assembly includes a cannula having a proximal portion and an opposing distal portion. The distal portion is configured to extend into a patient body. The cannula defines an access channel between the proximal portion and the distal portion, wherein the access channel is configured to receive a scope such that the scope can be maneuvered through the access channel to a location within the patient body. A cleaning element at the distal portion is configured to contact at least a distal end of the scope.

Abstract: A positive feed tool may include a motor, a gear head and a spindle. The gear head may be operably coupled to the motor and may include a drive assembly and a feed assembly. The spindle may be operably coupled to the gear head and may be selectively driven rotationally and fed axially based on operation of the drive assembly and the feed assembly, respectively. The feed assembly may include a feed rate oscillator having a fixed cam and a movable cam operably coupled to each other via a plurality of rolling elements to oscillate between a maximum width and a minimum width of the feed rate oscillator based on a position of the movable cam. The rolling elements alternate between a first state in which at least some of the rolling elements are unloaded and a second state in which all of the rolling elements are loaded.

Abstract: A medical device comprising a composition comprising a therapeutically active amount of active agent, a zinc compound, and an array of microneedles. The zinc compound may be selected from the group consisting of zinc, pharmaceutically acceptable salts of zinc, and mixtures thereof. At least a portion of the composition is present as a coating on at least a portion of the microneedles. Methods of delivering a therapeutically active agent to a mammal using compositions of the disclosure are also included.

Abstract: The present disclosure relates to a housing for a laparoscopic trocar assembly with an integrated scope-cleaning structure. The housing may include a shell forming a wall portion of a chamber and a cleaning element forming at least a portion of an internal surface of the chamber, the cleaning element configured to remove debris from a distal end of a scope upon contact between the cleaning element and the distal end of the scope. The cleaning element may be movable with respect to the shell of the housing in response to an input force upon the shell that moves a portion of the shell and a portion of the cleaning element between a default state and a displaced state.

Abstract: The present disclosure relates to a trocar assembly with an integrated scope-cleaning structure. The trocar assembly may include a chamber with a proximal opening configured to receive a distal end of a scope. A cannula extend distally from the chamber and may be configured to extend distally into a patient body. The cannula may be further configured to receive the distal end of the scope such that the scope can be maneuvered through the cannula to a location within the patient body. The trocar assembly may include a cleaning element forming a surface within the chamber, where the surface of the cleaning element is configured to remove debris from at least one non-longitudinal, end-facing surface of the scope.

Abstract: The present disclosure relates to a trocar assembly with an integrated scope-cleaning structure. The trocar assembly may include a housing defining boundaries of a chamber with (a) a proximal opening configured to receive a distal end of a scope, and (b) a distal opening in fluid and mechanical communication with a trocar cannula. The trocar assembly may further include a cleaning element located at least partially between the proximal opening and the distal opening, where the cleaning element is movable with respect to the housing from at least a first setting where a first portion of the cleaning element may be in a first location and may form a first cleaning surface within the chamber, the first cleaning surface configured to remove debris from a distal end of the scope when the distal end of the scope contacts the first portion of the cleaning element.