Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.

Abstract: A system and method are provided that, among other things, can reduce the burden on receiving computers, increase data throughput, reduce system failure, and provide components of a scalable and flexible network architecture. Specifically, the system and method provide a multichannel-multicast network environment for use in dynamically assigning data to channels. This configuration is particularly useful in a trading network environment, as it effectively performs channel reassignments in a way not to disturb the receipt of the underlying data. While the example embodiments described herein pertain to electronic trading, the principles of the present invention may be equally applied in other environments where the advantages presented herein are beneficial.

Abstract: Device for spray coating embraces a wire arc spray head that includes arc-making contact points and a carrier gas outlet, which is configured to swivel with feed wire in a pivoting motion. The device can be operated to spray coat a work piece.

Abstract: An applicator for a syringe is provided that includes a hub configured to be disposed at least partially within a nozzle of the syringe and defining a fluid passage therethrough, with one or barbs on the hub that frictionally and sealingly engage an interior of the nozzle in a manner minimizing void space associated with waste of deliverable material, and an applicator tip extending distally from the hub. The barb(s) may have varying diameters in order to enable the applicator to be engaged and utilized with syringes having different diameter nozzles. Further the fluid passage through the hub and applicator tip is dimensioned to minimize the volume of material that is retained within the applicator after use, thereby increasing the volume of material that can dispensed from the syringe for use in a procedure or procedures and minimize waste.

Abstract: The system for an antenna assembly for use on unmanned underwater vehicles (UUV). The antennas are low-cost, lightweight, single-use, and have a small form factor amenable to use on a micro-UUV. A central post and pivotally attached arms form an antenna (e.g., a monopole) that is lifted via an aerial, kite, or the like, when deployed from the UUV to extend the line of site of the antenna several meters above the surface of the water. In some cases, the antenna may be used on a number of UUVs in a swarm formation.

Abstract: An applicator for a syringe is provided that includes a hub configured to be disposed at least partially within a nozzle of the syringe and defining a fluid passage therethrough, with one or barbs on the hub that frictionally and sealingly engage an interior of the nozzle in a manner minimizing void space associated with waste of deliverable material, and an applicator tip extending distally from the hub. The barb(s) may have varying diameters in order to enable the applicator to be engaged and utilized with syringes having different diameter nozzles. Further the fluid passage through the hub and applicator tip is dimensioned to minimize the volume of material that is retained within the applicator after use, thereby increasing the volume of material that can dispensed from the syringe for use in a procedure or procedures and minimize waste.

Abstract: A pressurized medicinal composition comprising at least 40%, by weight, of liquid carbon dioxide, a fluid that forms a homogeneous solution with liquid carbon dioxide, and at least one active pharmaceutical ingredient dissolved or suspended in the composition. The composition may have a liquid to supercritical transition temperature greater than 40° C. Also, metered dose inhalers comprising an actuator, and a canister equipped with a metering valve, wherein the canister houses a reservoir comprising a pressurized carrier fluid mixture for dissolving or suspending at least one active pharmaceutical ingredient, the carrier fluid mixture comprising liquid carbon dioxide and a second component that is a liquid at room temperature and pressure.

Abstract: Systems, apparatuses, and methods for implementing flexible dictionary sharing techniques for caches are disclosed. A set-associative cache includes a dictionary for each data array set. When a cache line is to be allocated in the cache, a cache controller determines to which set a base index of the cache line address maps. Then, a selector unit determines which dictionary of a group of dictionaries stored by those sets neighboring this set would achieve the most compression for the cache line. This dictionary is then selected to compress the cache line. An offset is added to the base index of the cache line to generate a full index in order to map the cache line to the set corresponding to this chosen dictionary. The compressed cache line is stored in this set with the chosen dictionary, and the offset is stored in the corresponding tag array entry.

Abstract: A pressure regulator for an x-ray apparatus includes a piston housing having a recess formed therein and a piston seated in the recess. The piston is free to reciprocate, and define a variable volume chamber, within the recess. A circumferential groove is formed in an exterior surface of the piston, and a seal is seated in the circumferential groove. A manifold in the piston housing places the chamber in fluid communication with an exterior of the piston housing.

Abstract: The present invention includes embodiments of systems and methods for addressing the interdependencies that result from integrating the computing resources of multiple hardware and software providers. The integrated, multi-provider cloud-based platform of the present invention employs abstraction layers for communicating with and integrating the resources of multiple back-end hardware providers, multiple software providers and multiple license servers. These abstraction layers and associated functionality free users not only from having to implement and configure provider-specific protocols, but also from having to address interdependencies among selected hardware, software and license servers on a job-level basis or at other levels of granularity.

Abstract: The systems described herein provide a remote keyboard service for a media device on a computing device without having to invoke an application or unlock the computing device. The computing device can receive a message indicating that a text input field on the other device is selected and present a notification to the user prompting the user to invoke the virtual keyboard on the computing device to provide text input to the selected text input field. The computing device can receive user input selecting the notification and present a virtual keyboard for providing text input to the other device. The computing device can receive keyboard input from the user selecting characters and send the characters to the other device. The other device can then user the characters as text input to the selected text input field.

Abstract: A system and methods are provided for using order descriptor identifiers in relation to orders being used in trading strategies. According to one example method, when a hedge order is submitted upon detecting a fill of another order, the hedge order includes one or more order descriptor identifiers conveying a purpose of the hedge order to a user. The order descriptor identifiers can be used to search for desired orders and perform more effective order management and post trade analysis.

Abstract: Techniques are disclosed relating to user authentication. In some embodiments, a first computing device receives, from a second computing device, a request for a user credential to be input into an authentication prompt associated with the second device. The first computing device determines a proximity associated with the second computing device based on a received wireless location beacon and, based on the request and the determined proximity, presents a selection prompt asking a user of the first computing device to select a user credential stored in the first computing device. The first computing device then provides the selected user credential to the second computing device to input into the authentication prompt. In some embodiments, the first computing device receives the wireless location beacon from a remote controller of the second computing device and determines a proximity based on a signal strength associated with the received location beacon.

Abstract: The present invention relates to a process for producing a composition comprising an aqueous medium and, disposed in the aqueous medium, a first volume of a first hydrogel, which process comprises: (i) providing a composition comprising a first hydrophobic medium and, disposed in the first hydrophobic medium, a first volume of a first hydrogel; (ii) disposing a volume of an aqueous composition comprising a hydrogel compound around the first volume of the first hydrogel; (iii) allowing the aqueous composition comprising the hydrogel compound to form a gel and thereby forming a hydrogel object, which hydrogel object comprises the first volume of the first hydrogel and a second volume of a second hydrogel, which second volume of the second hydrogel is disposed around the first volume of the first hydrogel; and (iv) transferring the hydrogel object from the first hydrophobic medium to an aqueous medium and thereby producing the composition comprising the aqueous medium and, disposed in the aqueous medium, the fir

Abstract: A system and method are provided that, among other things, can reduce the burden on receiving computers, increase data throughput, reduce system failure, and provide components of a scalable and flexible network architecture. Specifically, the system and method provide a multichannel-multicast network environment for use in dynamically assigning data to channels. This configuration is particularly useful in a trading network environment, as it effectively performs channel reassignments in a way not to disturb the receipt of the underlying data. While the example embodiments described herein pertain to electronic trading, the principles of the present invention may be equally applied in other environments where the advantages presented herein are beneficial.

Abstract: The present invention provides compositions of bioactive dental materials that form a mineral apatite bond between the dental material and tooth structure for increasing bond strength and longevity. Also disclosed are methods for using said compositions in treating teeth.

Abstract: An applicator for a syringe is provided that includes a hub configured to be disposed at least partially within a nozzle of the syringe and defining a fluid passage therethrough, with one or barbs on the hub that frictionally and sealingly engage an interior of the nozzle in a manner minimizing void space associated with waste of deliverable material, and an applicator tip extending distally from the hub. The barb(s) may have varying diameters in order to enable the applicator to be engaged and utilized with syringes having different diameter nozzles. Further the fluid passage through the hub and applicator tip is dimensioned to minimize the volume of material that is retained within the applicator after use, thereby increasing the volume of material that can dispensed from the syringe for use in a procedure or procedures and minimize waste.

Abstract: An annular cutting tool and related methods are provided for herein that exhibit improved durability, cutting performance, and/or reduced heat generation for bone graft resections. The annular cutting tool can include an annular body having cutting teeth with a flat, flared distal tip for greater durability. An extended gullet can be disposed between groups of adjacent cutting teeth to improve removal of bone debris away from the cutting teeth more and thus prevent binding during use. The annular cutting body can have a recessed surface portion to reduce the area of direct contact to bone and thus reduce heat generated. The recessed surface portion can also provide an area in which bone debris can accumulate away from the cutting teeth to prevent or reduce binding of the tool during use. The annular cutting body can also include a drill bit for drilling a hole in a resected bone graft.

Abstract: A system comprising a head worn display and an image rendering computing device is disclosed. The head worn display comprises one or more image sensors, a head position sensor, and a head position computing device configured to determine a first head pose. The image rendering computing device is configured to render an enhanced image and embed the first head pose in the enhanced image. The head position computing platform is further configured to determine a second head pose, determine a difference between the second head pose and the first head pose, and warp the enhanced image based on the difference between the second head pose and the first head pose to correct for head motion of the user.