Abstract: The present disclosure relates to drug delivery devices, and in particular, to drug delivery devices configured to reconstitute a lyophilized drug powder into liquid form prior to delivery into a patients body. In some embodiments, such devices include a flexible drug reservoir having a proximal reservoir component storing a liquid diluent and a distal reservoir component storing a lyophilized drug powder, wherein the two compartments are separated by a frangible seal. A compression member may be positioned above the reservoir and held up by a releasable mechanism. When released, the compression member may be driven downwards to compress the proximal compartment so as to break the frangible seal and allow the diluent to mix with the drug powder and form a liquid drug mixture, and then to eject the liquid drug mixture from the reservoir.

Abstract: Disclosed herein are systems, devices, and processes for gesture detection. A method includes capturing a series of images. The method includes generating motion isolation information based on the series of images. The method includes generating a composite image based on the motion isolation information. The method includes determining a gesture based on the composite image. The processes described herein may include the use of convolutional neural networks on a series of time-related images to perform gesture detection on embedded systems or devices.

Abstract: An animal-harness includes a line, two crimps along the line, and a ring. The line is formed at one end. The two parallel lines formed by the bight are crimped together by both crimps. The two crimps are spaced apart, and the lines therebetween form a gap. Through this gap, the line may be passed through to form a loop. The line of the bight may pass through the ring. This ring is large enough for the long end of the line to pass through it as well, so that another loop may be formed. Thusly, in use, two loops or formed. One loop may be passed around an animal collar region, and another around an animal girth, to form a secure and safe harness around the animal. The remaining length of the line is available to be used as a leash.

Abstract: In one aspect of the invention, a method of charging a medical device includes receiving radiofrequency signals from a remote machine remote from the medical device via a receiver of the medical device. The method includes converting the radiofrequency signals into electrical energy via a generator of the medical device. The method includes storing the electrical energy in an energy cell of the medical device. The method also includes powering a power consumption component of the medical device by transmitting the energy from the energy cell to the power consumption component.

Abstract: A method of manufacturing a carbon nanotube product comprising: blending an unaligned carbon nanotube material with solid solvent particles; activating a nanotube solvent by liquefying the solid solvent particles; producing a nanotube dope solution by mixing the nanotube solvent and the unaligned carbon nanotube material; forming a carbon nanotube proto-product by extruding the nanotube dope solution; and forming an aligned carbon nanotube product by solidifying the carbon nanotube proto-product.

Abstract: A method may compiling, using at least one processor, a corpus of training data by obtaining, for each respective concept object in an ontology, a respective concept label and respective annotations describing the respective concept object; generating a vocabulary of terms based on the corpus of training data; training a semantic model using the corpus of training data and the vocabulary of terms, wherein input features for the semantic model are based on context words in proximity to a term in the vocabulary of terms; and storing a set of word embeddings for the vocabulary of terms based on the trained semantic model.

Abstract: Techniques for measuring metabolic tissue state and oxygenation in human or animal models, through optical techniques capable of simultaneous measurement at single region of interest. Simultaneously measuring CCO, oxygenated hemoglobin (HbO), and deoxygenated (HbR) hemoglobin is performed and metabolic activity of the tissue is determined. The methods employ a super-continuum light source and a probe to deliver light to the individual, and reflected light from the individual is analyzed to determine the metabolic function of the individual.

Abstract: A method of performing a complex Fourier transform of an input function including amplitude and phase information, including decomposing the input function into a plurality of sub-functions, wherein the Fourier transform of each sub-function includes an amplitude function and a phase function in which the phase is constrained to a plurality of possible phase values. The phase function of the Fourier transform of each sub-function is determined with an optical system that measures the amplitude function of an optical Fourier transform of the sub-function and changes in the amplitude function of the optical Fourier transform caused by applying a perturbation function to the sub-function. The determined phase functions and the measured amplitude functions are combined for each of the sub-functions to form the complex Fourier transform of the input function.

Abstract: A surface cleaning apparatus is provided with a dispensing system for applying a treating agent stored on the surface cleaning apparatus to the surface to be cleaned. The dispensing system can include at least one container for storing a supply of treating agent and a dispenser for dispensing the treating agent to the surface to be cleaned. The dispensing system uses filtered working exhaust air to blow treating agent off the treating agent dispenser.

Abstract: In one aspect of the present disclosure, a tissue retraction system may include a first anchor, a second anchor, and an elongate coupling member extending between the first anchor and the second anchor. The system also may include a holder for receiving the first anchor, the second anchor, and the elongate coupling element. The holder may include a proximal portion and a distal portion. The distal portion may have a smaller width than the proximal portion such that the distal portion exerts a force on a proximal end of the first anchor during deployment of the first anchor from the holder. The force may move the first anchor into an open configuration for receiving tissue.

Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue retraction device includes a first tissue engagement member coupled to an elastic member by a coupling assembly. The coupling assembly including a first coupler body having a first end region and a first compression member. Further, the first end region of the first coupler body is configured to extend into a portion of a lumen of the elastic member and the compression member is designed to compress the elastic member onto the first coupler body such that the elastic member is fixedly engaged with the coupler body.

Abstract: Exemplary embodiments described in this disclosure can pertain to a controller apparatus that provides control signals to a power generation unit. The controller apparatus can include a first controller, a second controller, and a supervisor that can place the first controller in an in-service state and the second controller in a standby state. The first controller provides control signals to the power generation unit when in the in-service state. The second controller can include a copy of an application program contained in the first controller. This copy of the application program can be modified or replaced while the second controller is in the standby state. The supervisor may then opt to place the second controller in the in-service state and place the first controller in the standby state. The switch-over of controllers is carried out in a substantially simultaneous manner that eliminates interruption in control operations.

Abstract: Compositions and designs are described for a sectional porous carrier used in processing microelectronics where thin device substrates are affixed by adhesive to the carrier and form an impervious bonded stack that is resistant to thermal and chemical products during processing and is easily handled by a substrate handling vacuum robot, and subsequently allows rapid removal (debonding) in batch operations by directional penetration into sectional porous regions by selective liquids which release the carrier from the device wafer without harm. The invention carrier with porous regions is used for temporary support of thin and fragile device substrates having capabilities of selective penetration of chemical liquids to pass through the porous regions, access and breakdown the bonding adhesive, and allow it to release without damage to the device substrate.

Abstract: Disclosed herein are systems, devices, and processes for gesture detection. A method includes capturing a series of images. The method includes generating motion isolation information based on the series of images. The method includes generating a composite image based on the motion isolation information. The method includes determining a gesture based on the composite image. The processes described herein may include the use of convolutional neural networks on a series of time-related images to perform gesture detection on embedded systems or devices.

Abstract: In one aspect of the present disclosure, a tissue retraction system may include a first anchor, a second anchor, and an elongate coupling member extending between the first anchor and the second anchor. The system also may include a holder for receiving the first anchor, the second anchor, and the elongate coupling element. The holder may include a proximal portion and a distal portion. The distal portion may have a smaller width than the proximal portion such that the distal portion exerts a force on a proximal end of the first anchor during deployment of the first anchor from the holder. The force may move the first anchor into an open configuration for receiving tissue.

Abstract: The invention is directed to substituted pyridine derivatives. Specifically, the invention is directed to compounds according to Formula (Iar): wherein Yar, X1ar, X2ar, R1ar, R2ar, R3ar, R4ar and R5ar are as defined herein; or a pharmaceutically acceptable salt or prodrug thereof. The compounds of the invention are selective inhibitors of DNMT1 and can be useful in the treatment of cancer, pre-cancerous syndromes, beta hemoglobinopathy disorders, sickle cell disease, sickle cell anemia, and beta thalassemia, and diseases associated with DNMT1 inhibition. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting DNMT1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

Abstract: A vacuum cleaner is provided with a dispensing system for applying a treating agent stored on the vacuum cleaner to the surface to be cleaned. The dispensing system can include at least one container for storing a supply of treating agent and a dispenser for dispensing the treating agent to the surface to be cleaned. The dispensing system uses filtered working exhaust air to blow treating agent off the treating agent dispenser.

Abstract: An animal-harness includes a line, two crimps along the line, and a ring. The line is formed at one end. The two parallel lines formed by the bight are crimped together by both crimps. The two crimps are spaced apart, and the lines therebetween form a gap. Through this gap, the line may be passed through to form a loop. The line of the bight may pass through the ring. This ring is large enough for the long end of the line to pass through it as well, so that another loop may be formed. Thusly, in use, two loops or formed. One loop may be passed around an animal collar region, and another around an animal girth, to form a secure and safe harness around the animal. The remaining length of the line is available to be used as a leash.

Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue retraction device includes a first tissue engagement member coupled to an elastic member by a coupling assembly. The coupling assembly including a first coupler body having a first end region and a first compression member. Further, the first end region of the first coupler body is configured to extend into a portion of a lumen of the elastic member and the compression member is designed to compress the elastic member onto the first coupler body such that the elastic member is fixedly engaged with the coupler body.

Abstract: An optical processing system comprises at least one spatial light modulator, SLM, configured to simultaneously display a first input data pattern (a) and at least one data focusing pattern which is a Fourier domain representation (B) of a second input data pattern (b), the optical processing system further comprising a detector for detecting light that has been successively optically processed by said input data patterns and focusing data patterns, thereby producing an optical convolution of the first and second input data patterns, the optical convolution for use in a neural network.