Patents by Inventor Alexander Mark

Alexander Mark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATMENT OF BILE ACID-RELATED DISORDERS AND PREDICTION OF CLINICAL SENSITIVITY TO TREATMENT OF BILE ACID-RELATED DISORDERS
    Publication number: 20200164036
    Abstract: Provided herein are methods of using 7?-hydroxy-4-cholesten-3-one (C4) in predicting the clinical sensitivity to treatment of bile acid-related and associated disorders with treatment peptides, such as variants of fibroblast growth factor 19 (FGF19) proteins and peptide sequences (and peptidomimetics) and fusions of FGF19 and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), and variants of fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics).
    Type: Application
    Filed: September 5, 2019
    Publication date: May 28, 2020
    Inventors: Alexander Mark DEPAOLI, Jian LUO, Hui TIAN
  • ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES
    Publication number: 20200101009
    Abstract: An oral film in an individual unit dose for delivery of one or more actives is disclosed herein, the film having a precisely calculated and controlled active dissolution profile. A wide variety of actives may be used, including, for example, clobazam, diazepam, or riluzole. Also disclosed are methods of treating a variety of diseases and conditions, for example, epilepsy and seizures, by administering the oral film disclosed herein.
    Type: Application
    Filed: September 5, 2019
    Publication date: April 2, 2020
    Inventors: Alexander Mark Schobel, Stephen Wargacki, Vincent J. Buono, Susan Shumard, Christopher James Santee
  • Enforcing granular access control policy
    Patent number: 10609041
    Abstract: An example method of enforcing granular access policy for embedded artifacts comprises: detecting an association of an embedded artifact with a resource container; associating the embedded artifact with at least a subset of an access control policy associated with the resource container; and responsive to receiving an access request to access the embedded artifact, applying the access control policy associated with the resource container for determining whether the access request is grantable.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: March 31, 2020
    Assignee: Palantir Technologies Inc.
    Inventors: Peter Wilczynski, Arseny Bogomolov, Alexander Mark, Teofana Hadzhiganeva, Kevin Ng, Nathaniel Klein, Sharon Hao
  • Protected search
    Patent number: 10599663
    Abstract: Systems and methods are provided for protected search. A search query to be performed using at least one data store is received from a computing device of a user. The user is not authorized to access the at least one data store. One or more search results that are responsive to the search query from the at least one data store are determined. The one or more search results are aggregated based on one or more categories. At least a subset of the aggregated search results is provided to the computing device of the user.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: March 24, 2020
    Assignee: Palantir Technologies Inc.
    Inventors: Alexander Mark, Christopher Richbourg, James Lu, Joshua Zavilla
  • SYSTEM AND METHOD FOR MAKING PERSONALIZED INDVIDUAL UNIT DOSES CONTAINING PHARMACEUTICAL ACTIVES
    Publication number: 20190388302
    Abstract: Systems and methods for making and delivering personalized, medically prescribed pharmaceuticals to an individual patient are described. Individual unit doses (IUDs) of medicine may be prepared specific to the individual in need of same, by using a system, which includes a networked control system in combination with manufacturing assemblies specific to the IUDs and delivering the medicine to the patient directly from the manufacturer.
    Type: Application
    Filed: June 20, 2019
    Publication date: December 26, 2019
    Applicant: Aquestive Therapeutics, Inc.
    Inventors: Alexander Mark Schobel, Keith Kendall, Dan Barber, Theresa Wood, Peter Boyd, John Maxwell
  • BIOREACTOR SYSTEM AND METHOD OF BIOPROCESSING
    Publication number: 20190367856
    Abstract: A bioreactor system includes a vessel having a bottom floor, a flexible bioprocessing bag disposed within the vessel, and a flexible bladder positioned intermediate the bottom floor of the vessel and the bioprocessing bag. The flexible bladder is selectively inflatable to vary at least one of a geometry or configuration of the bioprocessing bag to provide for improved drainability or an increased turndown ratio for the bioreactor system.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 5, 2019
    Applicant: GE HEALTHCARE BIO-SCIENCES CORP.
    Inventor: ALEXANDER MARK KILAR
  • Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
    Patent number: 10434144
    Abstract: Provided herein are methods of using 7a-hydroxy-4-cholsten-3-one (C4) in predicting the clinical sensitivity to treatment of bile acid-related and associated disorders with treatment peptides, such as variants of fibroblast growth factor 19 (FGF19) proteins and peptide sequences (and peptidomimetics) and fusions of FGF19 and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), and variants of fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics).
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: October 8, 2019
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Alexander Mark Depaoli, Jian Luo, Hui Tian
  • MODIFIED INDIGO COMPOUNDS AND METHODS OF DYEING A SUBSTRATE USING A MODIFIED INDIGO COMPOUND
    Publication number: 20190256710
    Abstract: The present disclosure provides dye compounds for use in dyeing textiles.
    Type: Application
    Filed: June 22, 2017
    Publication date: August 22, 2019
    Inventors: Sudhakar PUVVADA, Dennis SCHEER, Paul Gerard HOERTZ, Amsarani RAMAMOORTHY, Rajeev RAJBHANDARI, Caroline Elizabeth HAGERMAN, Alexander Peter Dirk MASSEY, Alexander Mark HELLAWELL, Asadollah FALLAH, Ruhksana QUYOUM
  • ARTICLE OF FOOTWEAR WITH RIBBED OUTSOLE AND NOTCHED MIDSOLE
    Publication number: 20190223548
    Abstract: A sole for an article of footwear includes an outsole that has longitudinal ribs and a midsole that is disposed above the outsole and that defines notches. The longitudinal ribs are disposed in the notches.
    Type: Application
    Filed: December 31, 2018
    Publication date: July 25, 2019
    Inventors: Michel Reginald LUSSIER, Matteo Edmond Padovani, George Alan Robusti, Alexander Mark Brill, Christopher Nelson Padilla
  • INTEGRATED DATA ANALYSIS
    Publication number: 20190220455
    Abstract: Systems and methods are provided for integrated data analysis. At least one object that is responsive to a first search query is determined. The object is stored in an object model that is managed by a first computing platform, and the at least one object is associated with one or more properties. One or more data sets that are responsive to a second search query are determined. The data sets are managed by a second computing platform. The one or more data sets are determined related to the at least one object. The at least one object is updated to include at least one property that references at least one analysis that relies on the one or more data sets.
    Type: Application
    Filed: March 28, 2019
    Publication date: July 18, 2019
    Inventors: Alexander Mark, Andrew Elder, Caitlin Colgrove, Daniel O'Malley, Hannah Korus, Michael Barone, Sharon Hao, William Rhyne
  • Fiber sensor
    Patent number: 10338000
    Abstract: There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and is arranged for exposure to an intake species. A photoconducting element is in optical communication with the transduction element. At least one pair of electrically conducting electrodes are in electrical connection with the photoconducting element. The pair of electrodes extend the fiber length.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: July 2, 2019
    Assignees: Massachusetts Institute of Technology, FLIR Systems, Incorporated
    Inventors: Alexander Gumennik, Alexander Mark Stolyarov, Brent Richard Schell, Chong Hou, Guillaume Romain Lestoquoy, Fabien Sorin, William Richard McDaniel, II, Yoel Fink, Aimee Rose, John Dimitris Joannopoulos
  • COLLABORATING USING DIFFERENT OBJECT MODELS
    Publication number: 20190163677
    Abstract: Systems and methods are provided for collaborating with different object models. Data corresponding to one or more source objects is received. The source objects is stored in a first object model, and each of the source objects is associated with information describing an entity. Matches between the respective information associated with the one or more source objects and respective information associated with one or more target objects are determined based on a query. The target objects are stored in a second object model. The one or more source objects are ranked based at least in part on the matches. A list of the ranked source objects are provided through an interface, the interface indicating a number of matching target objects for each of the source objects.
    Type: Application
    Filed: January 9, 2019
    Publication date: May 30, 2019
    Inventors: Alexander Mark, Andrew Elder
  • Integrated data analysis
    Patent number: 10289711
    Abstract: Systems and methods are provided for integrated data analysis. At least one object that is responsive to a first search query is determined. The object is stored in an object model that is managed by a first computing platform, and the at least one object is associated with one or more properties. One or more data sets that are responsive to a second search query are determined. The data sets are managed by a second computing platform. The one or more data sets are determined related to the at least one object. The at least one object is updated to include at least one property that references at least one analysis that relies on the one or more data sets.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: May 14, 2019
    Assignee: Palantir Technologies Inc.
    Inventors: Alexander Mark, Andrew Elder, Caitlin Colgrove, Daniel O'Malley, Hannah Korus, Michael Barone, Sharon Hao, William Rhyne
  • DELIVERY PHARMACEUTICAL COMPOSITIONS INCLUDING PERMEATION ENHANCERS
    Publication number: 20190091281
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: September 26, 2018
    Publication date: March 28, 2019
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Stephen Paul Wargacki, Rajesh Kumar Kainthan, Alexander Mark Schobel
  • Collaborating using different object models
    Patent number: 10216811
    Abstract: Systems and methods are provided for collaborating with different object models. Data corresponding to one or more source objects is received. The source objects is stored in a first object model, and each of the source objects is associated with information describing an entity. Matches between the respective information associated with the one or more source objects and respective information associated with one or more target objects are determined based on a query. The target objects are stored in a second object model. The one or more source objects are ranked based at least in part on the matches. A list of the ranked source objects are provided through an interface, the interface indicating a number of matching target objects for each of the source objects.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: February 26, 2019
    Assignee: Palantir Technologies Inc.
    Inventors: Alexander Mark, Andrew Elder
  • PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERMEATION
    Publication number: 20190022022
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 24, 2019
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • ENHANCED DELIVERY EPINEPHRINE AND PRODRUG COMPOSITIONS
    Publication number: 20190022023
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 24, 2019
    Applicant: AQUESTIVE THERAPEUTICS, INC.
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • ENCODING AND ADAPTIVE, SCALABLE ACCESSING OF DISTRIBUTED MODELS
    Publication number: 20190018843
    Abstract: Systems, methods, and apparatus for accessing distributed models in automated machine processing, including using large language models in machine translation, speech recognition and other applications.
    Type: Application
    Filed: August 29, 2018
    Publication date: January 17, 2019
    Inventors: Franz Josef Och, Jeffrey Dean, Thorsten Brants, Alexander Mark Franz, Jay Ponte, Peng Xu, Sha-Mayn Teh, Jeffrey Chin, Ignacio E. Thayer, Anton Carver, Daniel Rosart, John S. Hawkins, Karel Driesen
  • Lubricating oil composition
    Patent number: 10160927
    Abstract: Lubricating composition comprising (i) base oil and (ii) a Verkade base compound having the formula (1): wherein R1, R2 and R3 are each independently selected from hydrogen and saturated or unsaturated, straight chain or branched, C1-C22 alkyl groups. The lubricating composition of the present invention exhibits improved base number retention and oxidative stability, particularly in the presence of a biofuel such as fatty acid alkyl ester.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: December 25, 2018
    Assignee: SHELL OIL COMPANY
    Inventors: Alexander Mark Robert James Hellawell, Robert Wilkinson, Alexander Peter Dirk Massely, Robert Moir, Stuart Browning, Richard Thomas Bown, Sravani Gullapalli
  • Display screen or portion thereof with graphical user interface
    Patent number: D879821
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: March 31, 2020
    Assignee: PALANTIR TECHNOLOGIES, INC.
    Inventors: Gilad Gray, Antoine Llorca, Alexander Mark, Jiaji Hu, Michelle Lee, Piotr Kwiatkowski, Shelby Pefley