Patents by Inventor Alexander Mark

Alexander Mark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Encoding and adaptive, scalable accessing of distributed models
    Patent number: 10089304
    Abstract: Systems, methods, and apparatus for accessing distributed models in automated machine processing, including using large language models in machine translation, speech recognition and other applications.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: October 2, 2018
    Assignee: Google LLC
    Inventors: Franz Josef Och, Jeffrey Dean, Thorsten Brants, Alexander Mark Franz, Jay Ponte, Peng Xu, Sha-Mayn Teh, Jeffrey Chin, Ignacio E. Thayer, Anton Carver, Daniel Rosart, John S. Hawkins, Karel Driesen
  • Inhibitors of UDP-galactopyranose mutase
    Patent number: 10080757
    Abstract: Compounds and salts thereof which are acyl-sulfonamides or certain carboxylic acids and which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention include 2-aminothiazoles and triazolothiadiazines, particularly 3,6,7-substituted-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines, and 2-amino and salts thereof. Methods for inhibiting growth or attenuating virulence of microbial pathogens including mycobacterium, for example, M. tuberculosis and M. smegmatis and Klebsiella, for example, Klebsiella pneumoniae. Methods for inhibiting eukaryotic human and animal pathogens, and fungi and nematodes in particular. Methods for treatment of infections by prokaryotic and eukaryotic pathogens employing compounds of the invention.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: September 25, 2018
    Inventors: Laura Lee Kiessling, Valerie Jean Winton, Alexander Mark Justen
  • PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERMEATION
    Publication number: 20180200198
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: October 3, 2017
    Publication date: July 19, 2018
    Applicant: MONOSOL RX, LLC
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • INTEGRATED DATA ANALYSIS
    Publication number: 20180189340
    Abstract: Systems and methods are provided for integrated data analysis. At least one object that is responsive to a first search query is determined. The object is stored in an object model that is managed by a first computing platform, and the at least one object is associated with one or more properties. One or more data sets that are responsive to a second search query are determined. The data sets are managed by a second computing platform. The one or more data sets are determined related to the at least one object. The at least one object is updated to include at least one property that references at least one analysis that relies on the one or more data sets.
    Type: Application
    Filed: March 30, 2017
    Publication date: July 5, 2018
    Inventors: Alexander Mark, Andrew Elder, Caitlin Colgrove, Daniel O'Malley, Hannah Korus, Michael Barone, Sharon Hao, William Rhyne
  • ENHANCED DELIVERY EPINEPHRINE COMPOSITIONS
    Publication number: 20180125977
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: September 27, 2017
    Publication date: May 10, 2018
    Applicant: MONOSOL RX, LLC
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • SYSTEMS, METHODS, USER INTERFACES AND ALGORITHMS FOR PERFORMING DATABASE ANALYSIS AND SEARCH OF INFORMATION INVOLVING STRUCTURED AND/OR SEMI-STRUCTURED DATA
    Publication number: 20180121524
    Abstract: Implementations for searching and analyzing large, object-oriented data sets in an efficient manner involving innovative user interface features and/or search algorithm functionality are disclosed. In one exemplary embodiment, a system may search for information and/or relationships based on specified search criteria and return results that may be displayed dynamically and further filtered or analyzed. Systems may involve object oriented database(s) and a software layer including a specialized user interface between the user and the database(s). The user interface may comprise various tools as well as predefined and configurable features that enable effective search of the data as well as display of search results that are configurable and readily managed to provide immediate and useful search results.
    Type: Application
    Filed: December 29, 2017
    Publication date: May 3, 2018
    Inventors: Timothy Yousaf, Alexander Mark, Sharon Hao, David Cohen, Andrew Elder, Daniel Lidor, Joel Ossher, Christopher Richbourg, Joshua Zavilla, Kevin Zhang
  • METHODS FOR TREATMENT OF BILE ACID-RELATED DISORDERS AND PREDICTION OF CLINICAL SENSITIVITY TO TREATMENT OF BILE ACID-RELATED DISORDERS
    Publication number: 20180110834
    Abstract: Provided herein are methods of using 7a-hydroxy-4-cholsten-3-one (C4) in predicting the clinical sensitivity to treatment of bile acid-related and associated disorders with treatment peptides, such as variants of fibroblast growth factor 19 (FGF19) proteins and peptide sequences (and peptidomimetics) and fusions of FGF19 and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), and variants of fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics).
    Type: Application
    Filed: November 6, 2015
    Publication date: April 26, 2018
    Inventors: Alexander Mark DEPAOLI, Jian LUO, Hui TIAN
  • ENHANCED DELIVERY EPINEPHRINE COMPOSITIONS
    Publication number: 20180104195
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: October 23, 2017
    Publication date: April 19, 2018
    Applicant: MONOSOL RX, LLC
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • Mobile multi sack dust collection apparatus
    Patent number: 9937454
    Abstract: An apparatus and method for collection of particulate matter includes a plenum chamber formed in an funnel or a frustum configuration that discharges into a distribution chute assembly. The distribution chute assembly includes a number of individual chutes, each equipped with a circular collar or collar groove at the outlet which facilitates the attachment of the cylindrical dust collection sacks. The plenum chamber, distribution chute assembly, and individual dust collection sacks are carried by a frame assembly.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: April 10, 2018
    Assignee: HALLIBURTON ENERGY SERVICES, INC.
    Inventors: Winfred T. Sedberry, Wesley Warren, Nitinkumar Pandurang Katke, Vishwajit Manajirao Ghatge, Rajesh Sanda, Atul Bhupal Bokane, Alexander Marks
  • Systems, methods, user interfaces and algorithms for performing database analysis and search of information involving structured and/or semi-structured data
    Patent number: 9881066
    Abstract: Implementations for searching and analyzing large, object-oriented data sets in an efficient manner involving innovative user interface features and/or search algorithm functionality are disclosed. In one exemplary embodiment, a system may search for information and/or relationships based on specified search criteria and return results that may be displayed dynamically and further filtered or analyzed. Systems may involve object oriented database(s) and a software layer including a specialized user interface between the user and the database(s). The user interface may comprise various tools as well as predefined and configurable features that enable effective search of the data as well as display of search results that are configurable and readily managed to provide immediate and useful search results.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: January 30, 2018
    Assignee: Palantir Technologies, Inc.
    Inventors: Timothy Yousaf, Alexander Mark, Sharon Hao, David Cohen, Andrew Elder, Daniel Lidor, Joel Ossher, Christopher Richbourg, Joshua Zavilla, Kevin Zhang
  • LUBRICATING OIL COMPOSITION
    Publication number: 20170362529
    Abstract: Lubricating composition comprising (i) base oil and (ii) a Verkade base compound having the formula (1): wherein R1, R2 and R3 are each independently selected from hydrogen and saturated or unsaturated, straight chain or branched, C1-C22 alkyl groups. The lubricating composition of the present invention exhibits improved base number retention and oxidative stability, particularly in the presence of a biofuel such as fatty acid alkyl ester.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 21, 2017
    Inventors: Alexander Mark Robert James HELLAWELL, Robert WILKINSON, Alexander Peter Dirk MASSELY, Robert MOIR, Stuart BROWNING, Richard Thomas BOWN, Sravani GULLAPALLI
  • ENHANCED DELIVERY EPINEPHRINE COMPOSITIONS
    Publication number: 20170348251
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: May 4, 2017
    Publication date: December 7, 2017
    Applicant: MONOSOL RX, LLC
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERMEATION
    Publication number: 20170290776
    Abstract: Pharmaceutical compositions having enhanced active component permeation properties are described.
    Type: Application
    Filed: May 4, 2017
    Publication date: October 12, 2017
    Applicant: MONOSOL RX, LLC
    Inventors: Alexander Mark Schobel, Stephanie Marie Varjan, Stephen Paul Wargacki
  • INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE
    Publication number: 20170258805
    Abstract: Compounds and salts thereof which are acyl-sulfonamides or certain carboxylic acids and which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention include 2-aminothiazoles and triazolothiadiazines, particularly 3,6,7-substituted-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines, and 2-amino and salts thereof. Methods for inhibiting growth or attenuating virulence of microbial pathogens including mycobacterium, for example, M. tuberculosis and M. smegmatis and Klebsiella, for example, Klebsiella pneumoniae. Methods for inhibiting eukaryotic human and animal pathogens, and fungi and nematodes in particular. Methods for treatment of infections by prokaryotic and eukaryotic pathogens employing compounds of the invention.
    Type: Application
    Filed: March 13, 2017
    Publication date: September 14, 2017
    Inventors: Laura Lee KIESSLING, Valerie Jean WINTON, Alexander Mark JUSTEN
  • ENCODING AND ADAPTIVE, SCALABLE ACCESSING OF DISTRIBUTED MODELS
    Publication number: 20170212887
    Abstract: Systems, methods, and apparatus for accessing distributed models in automated machine processing, including using large language models in machine translation, speech recognition and other applications.
    Type: Application
    Filed: April 6, 2017
    Publication date: July 27, 2017
    Applicant: Google Inc.
    Inventors: Franz Josef Och, Jeffrey Dean, Thorsten Brants, Alexander Mark Franz, Jay Ponte, Peng Xu, Sha-Mayn Teh, Jeffrey Chin, Ignacio E. Thayer, Anton Carver, Daniel Rosart, John S. Hawkins, Karel Driesen
  • Encoding and adaptive, scalable accessing of distributed models
    Patent number: 9619465
    Abstract: Systems, methods, and apparatus for accessing distributed models in automated machine processing, including using large language models in machine translation, speech recognition and other applications.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: April 11, 2017
    Assignee: GOOGLE INC.
    Inventors: Franz Josef Och, Jeffrey Dean, Thorsten Brants, Alexander Mark Franz, Jay Ponte, Peng Xu, Sha-Mayn Teh, Jeffrey Chin, Ignacio E. Thayer, Anton Carver, Daniel Rosart, John S. Hawkins, Karel Driesen
  • FILM DELIVERY SYSTEM FOR ACTIVE INGREDIENTS
    Publication number: 20170042830
    Abstract: The present invention includes a pharmaceutical-based film system which includes various small-scale forms of pharmaceutically active agents, including testosterone esters, in a film base. Such forms include nanoparticles, microparticles, and combinations thereof. Methods of producing such film and providing a dosage of the pharmaceutical in a film are also provided.
    Type: Application
    Filed: May 17, 2016
    Publication date: February 16, 2017
    Inventors: Garry L. Myers, Eric Dadey, Alexander Mark Schobel
  • Basalt fiber composite for antenna in well-logging
    Patent number: 9507045
    Abstract: A well-logging tool for a geological formation includes a housing to be positioned in a borehole and an antenna assembly carried by the housing. The antenna assembly includes an antenna housing having a recess therein. A dielectric material layer comprises a basalt fiber composite and is within the recess. At least one antenna coil is supported by the dielectric material layer. An electrical connector is coupled to the at least one antenna coil. Resistivity processing circuitry is coupled to the electrical connector to determine an electrical resistivity of the geological formation based on the at least one antenna coil.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: November 29, 2016
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Frank Espinosa, Golchehreh Salamat, Alexander Marks, Frederic Pauchet
  • Combination peptide-nanoparticles and delivery systems incorporating same
    Patent number: 9474687
    Abstract: Nanoparticles having a core and a corona of ligands covalently linked to the core, wherein differing species of peptides are bound to the nanoparticles and incorporated into various dosage forms.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: October 25, 2016
    Assignees: MONOSOL RX, LLC, MIDATECH LIMITED
    Inventors: Phillip Williams, Thomas Rademacher, Alexander Mark Schobel, Eric Dadey
  • Fluorination process
    Patent number: 9468694
    Abstract: The invention relates to a process for preparation of a compound of formula (I): R1 is selected from C1-6alkyl, C2-6alkenyl, and C2-6alkynyl; which comprises: (i) reaction with fluoride, suitably [18F]fluoride, of a corresponding compound of formula (II): wherein R2 is selected from hydrogen, C1-10alkyl, C1-10haloalkyl, C6-14aryl, C6-14arylalkyl, —(CH2CH2O)q—CH3 wherein q is an integer of from 1 to 10; R1 is as defined for the compound of formula (I); and R3 is a leaving group. Certain novel precursors of formula (II) and radiopharmaceutical kits containing such precursors are also claimed.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: October 18, 2016
    Assignee: GE Healthcare Limited
    Inventors: Anthony Eamon Storey, Clare Louise Jones, Denis Raymond Christophe Bouvet, Nicolas Lasbistes, Steven Michael Fairway, Lorenzo Williams, Alexander Mark Gibson, Robert James Nairne, Farhad Karimi, Bengt Langstrom