Abstract: A flow rate sensor comprising a body comprising an inlet and an outlet and a flight-tube interconnecting there between. A plurality of electrodes are disposed along the flight tube. The electrodes are electrically operable to introduce a marker to the fluid at a first position in the form of a local fluid composition variation and to detect the position of the marker at least at a second position downstream of the first position, thereby determining the displacement of a fluid volume in the flight-tube and infer the volumetric flow rate of the fluid at a flow pulse.

Abstract: A package comprising a container for holding a first substance, and a product insert for holding a second substance, at least partially inserted info said container, and where the first product and the second product can be allowed to merge by external manipulation of said package. Packaged products and methods are also provided.

Abstract: The present invention provides a drug delivery device comprising a drug reservoir chamber (15) containing a substance (16) to be delivered in fluid connection with a drug administration means (17) and (18), and a hydraulic control chamber (9) containing an electrically controlled, non-gassing, volume changing means (13), a coupling means (14) coupling said hydraulic control chamber (9) to said drug chamber (15), the arrangement being such that a change in the electrical control means (11) causes a change in the volume of the volume changing means (13), the volume change being conveyed by the coupling means (14) to the drug chamber (15) such that the substance (16) is expelled from the drug chamber (15) towards the drug administration means (17) and (18).

Abstract: The present application provides a drug-delivery device comprising a drug reservoir chamber 16, containing a substance to be delivered, in fluid connection with a drug administration means 18, and an electrically-controlled battery unit 10 comprising at least one displacement-generating battery cell 19 coupled to the drug reservoir chamber 16 by a coupling means 14, the arrangement being such that the displacement derived from the battery unit 10 is conveyed by the coupling means 14 to the drug reservoir chamber 16 such that the substance is expelled from the drug reservoir chamber 16 towards the drug administration means 18.

Abstract: A package for use with a beneficial agent delivery device. The package includes at least one filling chamber having a sealed penetrable access region, at least one compartment configured to hold a content, wherein the content includes at least one of a beneficial agent or a constituent of a beneficial agent, and at least one channel connecting the at least one filling chamber in fluid communication with the at least one compartment. At least a portion of the package is resealable to contain the content.

Abstract: The present application provides a drug-delivery device comprising a drug reservoir chamber 16, containing a substance to be delivered, in fluid connection with a drug administration means 18, and an electrically-controlled battery unit 10 comprising at least one displacement-generating battery cell 19 coupled to the drug reservoir chamber 16 by a coupling means 14, the arrangement being such that the displacement derived from the battery unit 10 is conveyed by the coupling means 14 to the drug reservoir chamber 16 such that the substance is expelled from the drug reservoir chamber 16 towards the drug administration means 18.

Abstract: A hypodermic drug delivery apparatus for delivering a pressurized medication fluid generally incorporates a reservoir containing at least one deliverable fluid, a reservoir pressurizing device, a rupturing member, a fluid administration device for communicating with the reservoir via a fluid passageway, and a rupture control mechanism for preventing rupture of a wall portion of the reservoir below a threshold pressure.

Abstract: A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port.

Abstract: A dispensing device comprises a sealed package including a collapsible compartment and an administration assembly. The administration assembly includes a delivery device in fluid communication with a substance within the sealed package. A compression panel collapses the compartment to dispense a substance through the delivery device. Embodiments for a single use dispenser for hypodermic administration of a unit dose of a therapeutic fluid, as well as therapeutic packages and methods for administering therapeutic substances to subjects, are also provided.

Abstract: A dispensing device includes a backing, at least a first product compartment and a fluid transport device. The backing is a frangible section adapted to at least partially open as the backing is moved from a first position toward a second position. The product compartment and the fluid transport device are each disposed on the backing in confronting relationship to the frangible section. According to a method, a dispensing device is provided in which the backing is moved from the first position toward the second position to compress the first product compartment and cause the content to be dispensed through the fluid transport device.

Abstract: A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments, and a fitment. The first compartment contains at least a first constintuent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir.

Abstract: A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments and a fitment. The first compartment contains at least a first constituent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir.

Abstract: A flow rate meter comprises a disposable fluid transport portion and a reusable interface connector removably attached to the transport portion. The transport portion includes a flow conduit having an input and an output, while the interface connector provides feedback to a desired location. First and second portions of control circuitry are, respectively, associated with the transport portion and the interface connector. The first circuitry portion includes a plurality of electrodes and derives flow rate. The device measures a range of flow rates and is adapted, for example, for use in micro-fluidic systems including fluids administration to a patient's body.

Abstract: A dry-powder inhaler device comprising an air inlet (40), an air outlet (4), an assembly comprising a mesh-based package (10) containing a dry-powder drug (16), the assembly being positioned to undergo agitation, the device having an airflow therethrough from the air inlet to the outlet, which airflow at least indirectly causes the agitation and wherein the agitation of the assembly in conjunction with the airflow causes the particles of the dry-powder drug to exit from the mesh-based package and become entrained in the airflow.

Abstract: A flow rate meter comprises a disposable fluid transport portion and a reusable interface connector removably attached to the transport portion. The transport portion includes a flow conduit having an input and an output, while the interface connector provides feedback to a desired location. First and second portions of control circuitry are, respectively, associated with the transport portion and the interface connector. The first circuitry portion includes a plurality of electrodes and derives flow rate. The device measures a range of flow rates and is adapted, for example, for use in micro-fluidic systems including fluids administration to a patient's body.

Abstract: A device for storing and dispensing a product comprising: a package comprising at least a first compartment having a flexible wall portion; a fluid transport device; and a backing associated with said package which, during dispensing, supports the package to facilitate expression of a product from the package through said fluid transport device.

Abstract: A dispensing device includes a backing, at least a first product compartment and a fluid transport device. The backing is a frangible section adapted to at least partially open as the backing is moved from a first position toward a second position. The product compartment and the fluid transport device are each disposed on the backing in confronting relationship to the frangible section. According to a method, a dispensing device is provided in which the backing is moved from the first position toward the second position to compress the first product compartment and cause the content to be dispensed through the fluid transport device.

Abstract: A package comprising a container for holding a first substance, and a product insert for holding a second substance, at least partially inserted info said container, and where the first product and the second product can be allowed to merge by external manipulation of said package. Packaged products and methods are also provided.

Abstract: A device for administering a therapeutic substance includes a sealed package and an administration assembly. The sealed package includes a collapsible compartment containing the substance. The administration assembly includes a dispenser that is in fluid communication with the substance. At least one compression member is movable by linear actuation to progressively collapse the collapsible compartment and urge the therapeutic substance through the dispenser.

Abstract: A flow rate meter comprises a disposable fluid transport portion and a reusable interface connector removably attached to the transport portion. The transport portion includes a flow conduit having an input and an output, while the interface connector provides feedback to a desired location. First and second portions of control circuitry are, respectively, associated with the transport portion and the interface connector. The first circuitry portion includes a plurality of electrodes and derives flow rate. The device measures a range of flow rates and is adapted, for example, for use in micro-fluidic systems including fluids administration to a patient's body.