Abstract: Accessories that can add new functionality to an electronic device. These accessories can provide additional functionality that allow for the replacement of a physical object that would otherwise be carried in addition to and separate from the electronic device. These accessories can further provide improvements, such as a reduction in size or improvement in functionality over the physical object to be replaced.

Abstract: Fully automated computer-implemented deep learning techniques of contrast-enhanced cardiac MRI segmentation are provided. The techniques may include providing cardiac MRI data to a first computer-implemented deep learning network trained in order to identify a left ventricle region of interest to generate left ventricle region-of-interest-identified cardiac MRI data. The techniques may also include providing the left ventricle region-of-interest-identified cardiac MRI data to a second computer-implemented deep learning network trained in order to identify myocardium to generate myocardium-identified cardiac MRI data. The techniques may further include providing the myocardium-identified cardiac MRI data to at least one third computer-implemented deep learning network trained to conform data to geometrical anatomical constraints in order to generate anatomical-conforming myocardium-identified cardiac MRI data.

Abstract: A magnetic alignment system can include a primary annular magnetic alignment component and a secondary annular magnetic alignment component. The primary alignment component can include an inner annular region having a first magnetic orientation, an outer annular region having a second magnetic orientation opposite to the first magnetic orientation, and a non-magnetized central annular region disposed between the primary inner annular region and the primary outer annular region. The secondary alignment component can have a magnetic orientation with a radial component. Additional features, such as a rotational magnetic alignment component and/or an NFC coil and circuitry can be included.

Abstract: A magnetic alignment system can include a primary annular magnetic alignment component and a secondary annular magnetic alignment component. The primary alignment component can include an inner annular region having a first magnetic orientation, an outer annular region having a second magnetic orientation opposite to the first magnetic orientation, and a non-magnetized central annular region disposed between the primary inner annular region and the primary outer annular region. The secondary alignment component can have a magnetic orientation with a radial component. Additional features, such as a rotational magnetic alignment component and/or an NFC coil and circuitry can be included.

Abstract: This disclosure provides methods and pharmaceutical compositions for reducing or eliminating cardiotoxicity, particularly cardiotoxicity induced by a cancer treatment or other therapy. In some cases, the methods and compositions prevent or reduce cardiotoxicity caused by anthracycline treatment. The methods provided herein often comprise administering a protective agent such as myricetin, tricetin, robinetin, ficetin, vitexin, quercetin, dihydrorobinetin, kaempferol, 7,3?,4?,5?-tetrahydroxyflavone, and myricitrin in conjunction with the administration of a cancer drug or other treatment. They may comprise administering a protective agent in combination with dexrazoxane. The compositions provided herein include co-formulations of a protective agent with a different protective agent or with a cancer treatment (e.g., anthracycline drug).

Abstract: Treatment of dilated cardiomyopathy in a subject by combination treatment with a tyrosine kinase inhibitor and a statin.

Abstract: Provided herein are compositions related to vaccines, e.g., influenza vaccines, including, peptide based vaccines, nucleic acid based vaccines, recombinant virus based vaccines, antibody based vaccines, and virus based vaccines. Also provided herein are methods related to vaccines, e.g., influenza vaccines, including methods of identifying epitopes for the vaccines, producing, formulating, and administering the vaccines.

Abstract: A magnetic alignment system can include a primary annular magnetic alignment component and a secondary annular magnetic alignment component. The primary alignment component can include an inner annular region having a first magnetic orientation, an outer annular region having a second magnetic orientation opposite to the first magnetic orientation, and a non-magnetized central annular region disposed between the primary inner annular region and the primary outer annular region. The secondary alignment component can have a magnetic orientation with a radial component. Additional features, such as a rotational magnetic alignment component and/or an NFC coil and circuitry can be included.

Abstract: A magnetic alignment system can include a primary annular magnetic alignment component and a secondary annular magnetic alignment component. The primary alignment component can include an inner annular region having a first magnetic orientation, an outer annular region having a second magnetic orientation opposite to the first magnetic orientation, and a non-magnetized central annular region disposed between the primary inner annular region and the primary outer annular region. The secondary alignment component can have a magnetic orientation with a radial component. Additional features, such as a rotational magnetic alignment component and/or an NFC coil and circuitry can be included.

Abstract: Disclosed are small molecule inhibitors of influenza HA, and methods of using them to treat or prevent HA-mediated diseases and conditions.

Abstract: A method for search construct validation is described. The method includes determining a construct of a search query recognized on a search engine of a third party webpage and related constructs represented in a plurality of search results generated based on the search query. The method includes mapping the determined construct to the related constructs represented in the plurality of search results generated based on the search query. The method includes generating a knowledge graph illustrating the mapping between the determined construct and the related constructs and a hierarchy and a strength of a conceptual relationship between the determined construct and the related constructs. The method includes displaying, via an interactive user interface, an interactive graph illustrating the mapping between the determined construct and the plurality of related constructs and the hierarchy and the strength of the conceptual relationship between the determined construct and the plurality of related constructs.

Abstract: A method for goal progression and visualization is described. The method includes generating a graph-like structure according to user specified goals along with their associated timeframes and desired outcomes. The method also includes converting the graph-like structure into a topological landscape of hills and valleys representing the user specified goals along with the associated timeframes and desired outcomes. The method further includes displaying the topological landscape of hills and valleys representing the user specified goals along with the associated timeframes and desired outcomes.

Abstract: A method for statistical data clarification is described. The method includes determining a relevance of statistical data according to a textual context of a statistical data detected within a document viewed by a user. The method also includes establishing a frame of reference for the statistical data according to the textual context and a determined relevance of the statistical data detected within the document viewed by the user. The method further includes generating, according to the frame of reference, at least one analogy that corresponds to the statistical data. The method also includes displaying the at least one analogy to the user to assist the user in understanding and using the statistical data.

Abstract: A method to generate a digital avatar simulating a human for behavioral empathy and understanding is described. The method includes training a neural network to generate the digital avatar to simulate the human according to a vector of human attributes and generate responses in response to interactions with a user based on the vector of human attributes. The method also includes interacting, by the user, with the digital avatar, in which the digital avatar initially having a similar background and attributes as the user. The method further includes modifying, over time, the attributes of the digital avatar to represent a target background and a target set of attributes different from the user.

Abstract: A system includes a processor configured to build a model of human behavior that can be assigned to a simulated human, where the model is trained on a dataset of interactions between humans, and parameters of the model can be adjusted. The processor is further configured to build a model of a task to be engaged in by a plurality of simulated humans, simulate interactions between the plurality of simulated humans, and display behavior of the simulated humans and information about the interactions between the simulated humans during simulated interactions.

Abstract: A system includes a processor configured to determine analogies between information associated with a new topic to be learned and information associated with existing knowledge of a user, identify terms associated with the new topic that appear similar to terms associated with the existing knowledge, and propose questions for the user to explore based on the new topic and the existing knowledge.

Abstract: A method for an augmented reality goal assistant is described. The method includes detecting an object associated with a behavioral goal of a user. The method also includes altering an appearance of the object based on the behavioral goal of the user. The method further includes displaying the altered appearance of a detected object on an augmented reality headset, such that the altered appearance of the detected object is modified based on the behavioral goal of the user.

Abstract: A proning device includes a conformable structure that adapts to the shape of a subject, surrounded by a shell that imparts a substantially elliptical cross-sectional shape to an exterior of the device to facilitate rotation of the subject within the device when the device is wrapped around the subject. A low-friction interface may also be provided to further facilitate rotation of the subject. The device advantageously reduces staffing needs for proning a subject while facilitating extended proning and periodic re-orientation of the subject. Also disclosed herein are methods for making and using such a proning device.

Abstract: The present invention includes methods for treating and/or preventing dilated cardiomyopathy due to an LMNA mutation, comprised of administering to a subject at-risk a therapeutically effective amount of an inhibitor of PDGF signaling.