Patents by Inventor An C. Wu

An C. Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising albumin-FMS-like tyrosine kinase 3 ligand fusion proteins and uses thereof
    Patent number: 11246908
    Abstract: The present invention provides a novel fusion protein of Flt3L and albumin and its use to increase the Flt3L half-life in vivo and to deliver Flt3L to immune cells in a subject to enhance alternative dendritic cell populations. Use of the fusion protein in combination with other chemotherapeutic, radiotherapeutic and immunotherapeutic methods are also provided.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: February 15, 2022
    Assignee: The Johns Hopkins University
    Inventors: T. C. Wu, Chien-Fu Hung, Brandon Krishna Lam
  • MICROFLUIDIC DEVICES WITH FLEXIBLE OPTICALLY TRANSPARENT ELECTRODES
    Publication number: 20220016626
    Abstract: Microfluidic devices in which electrokinetic mechanisms move droplets of a liquid or particles in a liquid are described. The devices include at least one electrode that is optically transparent and/or flexible.
    Type: Application
    Filed: August 13, 2021
    Publication date: January 20, 2022
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Pei-Yu E. Chiou, Kuo-Wei Huang, Igor Y. Khandros, Ming C. Wu
  • Center pintle hub
    Patent number: 11220801
    Abstract: A center pintle hub to be affixed to a base of a machine. The center pintle hub includes a base portion and a support portion. The base portion is formed to be affixed to the base. The support portion extends from the base portion and has a frusto-conical shape that can receive a center pintle shaft. The center pintle shaft can support a frame of the machine and provide rotation of the frame with respect to the base.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: January 11, 2022
    Assignee: Caterpillar Global Mining LLC
    Inventors: Joe A. Rapp, Cheng-Kong C. Wu, Vladimir A. Korchagin, Aruna Kinjarapu, Robin Varghese
  • INFLUENZA VACCINES
    Publication number: 20220002352
    Abstract: Provided herein are compositions related to vaccines, e.g., influenza vaccines, including, peptide based vaccines, nucleic acid based vaccines, recombinant virus based vaccines, antibody based vaccines, and virus based vaccines. Also provided herein are methods related to vaccines, e.g., influenza vaccines, including methods of identifying epitopes for the vaccines, producing, formulating, and administering the vaccines.
    Type: Application
    Filed: July 14, 2021
    Publication date: January 6, 2022
    Inventors: Arthur YOUNG, Ren SUN, Nicholas C. WU
  • DEP force control and electrowetting control in different sections of the same microfluidic apparatus
    Patent number: 11192107
    Abstract: A microfluidic apparatus can comprise a dielectrophoresis (DEP) configured section for holding a first liquid medium and selectively inducing net DEP forces in the first liquid medium. The microfluidic apparatus can also comprise an electrowetting (EW) configured section for holding a second liquid medium on an electrowetting surface and selectively changing an effective wetting property of the electrowetting surface. The DEP configured section can be utilized to select and move a micro-object in the first liquid medium. The EW configured section can be utilized to pull a droplet of the first liquid medium into the second liquid medium.
    Type: Grant
    Filed: April 25, 2015
    Date of Patent: December 7, 2021
    Assignee: Berkeley Lights, Inc.
    Inventors: Igor Y. Khandros, J. Tanner Nevill, Steven W. Short, Ming C. Wu
  • Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity
    Patent number: 11166936
    Abstract: This disclosure provides methods and pharmaceutical compositions for reducing or eliminating cardiotoxicity, particularly cardiotoxicity induced by a cancer treatment or other therapy. In some cases, the methods and compositions prevent or reduce cardiotoxicity caused by anthracycline treatment. The methods provided herein often comprise administering a protective agent such as myricetin, tricetin, robinetin, ficetin, vitexin, quercetin, dihydrorobinetin, kaempferol, 7,3?,4?,5?-tetrahydroxyflavone, and myricitrin in conjunction with the administration of a cancer drug or other treatment. They may comprise administering a protective agent in combination with dexrazoxane. The compositions provided herein include co-formulations of a protective agent with a different protective agent or with a cancer treatment (e.g., anthracycline drug).
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: November 9, 2021
    Assignees: Auransa Inc., SCT II LLC
    Inventors: Christopher G. Armstrong, Kevin J. Kim, Lisa Maria Lucia Pham, Eunhye Park, Zhong Zhong, Guanyi Huang, Joseph C. Wu, Sidney Paul Elmer, Viwat Visuthikraisee, Eithon Michael G. Cadag, Thomas Bernard Freeman, Pek Yee Lum
  • Microfluidic devices with flexible optically transparent electrodes
    Patent number: 11148139
    Abstract: Microfluidic devices in which electrokinetic mechanisms move droplets of a liquid or particles in a liquid are described. The devices include at least one electrode that is optically transparent and/or flexible.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: October 19, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Pei-Yu E. Chiou, Kuo-Wei Huang, Igor Y. Khandros, Ming C. Wu
  • Multi-mode interference (MMI) based laser devices for heterogeneous platforms
    Patent number: 11143818
    Abstract: Embodiments include apparatuses, methods, and systems including a laser device having a 1×3 MMI coupler within a semiconductor layer. A front arm is coupled to the MMI coupler and terminated by a front reflector. In addition, a coarse tuning arm is coupled to the MMI coupler and terminated by a first back reflector for coarse wavelength tuning, a fine tuning arm is coupled to the MMI coupler and terminated by a second back reflector for fine wavelength tuning, and a SMSR and power tuning arm is coupled to the MMI coupler and terminated by a third back reflector. A gain region is above the front arm and above the semiconductor layer. Other embodiments may also be described and claimed.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: October 12, 2021
    Assignees: INTEL CORPORATION, REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Meer Nazmus Sakib, Guan-Lin Su, John Heck, Haisheng Rong, Ming C. Wu
  • Linear interpolator of tabulated functions
    Patent number: 11132296
    Abstract: The embodiments herein store tabulated values representing a linear or non-linear function in separate memory banks to reduce the size of memory used to store the tabulated values while being able to provide upper and lower values for performing linear interpolation in parallel (e.g., the same cycle). To do so, a linear interpolation system includes a first memory bank that stores the even indexed tabulated values while a second memory bank stores the odd indexed tabulated values. During each clock cycle, the first and second memory banks can output upper and lower values for linear interpolation (although which memory bank outputs the upper value and which outputs the lower value can vary). Using the upper and lower values, the linear interpolation system performs linear interpolation to approximate the value of a non-linear function that is between the upper and lower values.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: September 28, 2021
    Assignee: XILINX, INC.
    Inventors: Ephrem C. Wu, Xiaoqian Zhang
  • Data transfers between a memory and a distributed compute array
    Patent number: 11127442
    Abstract: An integrated circuit (IC) includes a plurality of dies. The IC includes a plurality of memory channel interfaces configured to communicate with a memory, wherein the plurality of memory channel interfaces are disposed within a first die of the plurality of dies. The IC may include a compute array distributed across the plurality of dies and a plurality of remote buffers distributed across the plurality of dies. The plurality of remote buffers are coupled to the plurality of memory channels and to the compute array. The IC further includes a controller configured to determine that each of the plurality of remote buffers has data stored therein and, in response, broadcast a read enable signal to each of the plurality of remote buffers initiating data transfers from the plurality of remote buffers to the compute array across the plurality of dies.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: September 21, 2021
    Assignee: Xilinx, Inc.
    Inventors: Xiaoqian Zhang, Ephrem C. Wu, David Berman
  • Influenza vaccines
    Patent number: 11111277
    Abstract: Provided herein are compositions related to vaccines, e.g., influenza vaccines, including, peptide based vaccines, nucleic acid based vaccines, recombinant virus based vaccines, antibody based vaccines, and virus based vaccines. Also provided herein are methods related to vaccines, e.g., influenza vaccines, including methods of identifying epitopes for the vaccines, producing, formulating, and administering the vaccines.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: September 7, 2021
    Assignees: InvVax, Inc., The Regents of the University of California
    Inventors: Arthur Young, Ren Sun, Nicholas C. Wu
  • ZIP PULLER HOLDER ARRANGEMENT FOR LUGGAGE AND BAGS
    Publication number: 20210267322
    Abstract: A luggage article includes a body that includes a zippered opening (15) that has at least one zipper arrangement having a zipper tape (14). The zipper arrangement includes one or more zipper sliders (16, 20) and one or more zipper pull-tabs (18, 22). Each of the one or more zipper sliders (16, 20) is joined to a respective one of the one or more zipper pull-tabs (18, 22). The luggage article includes a means (26) for holding the one or more pull-tabs in a substantially perpendicular arrangement to the zipper tape (14) of the zipper arrangement.
    Type: Application
    Filed: June 20, 2018
    Publication date: September 2, 2021
    Inventor: Peter C. Wu
  • Multiple injector holes for gas turbine engine vane
    Patent number: 11053808
    Abstract: A vane comprises an airfoil extending from a radially outer platform to a radially inner platform. A pair of legs extend radially inwardly from the radially inner platform, and an air flow passage extends through the radially outer platform, through the airfoil, and into a chamber defined between the pair of legs. One of the pair of legs includes a plurality of injector holes, configured to allow air from the radially outer platform to pass outwardly of the holes. A gas turbine engine is also disclosed.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: July 6, 2021
    Assignee: Raytheon Technologies Corporation
    Inventors: Russell J. Bergman, Charles C. Wu, Brett Alan Bartling
  • DATA TRANSFERS BETWEEN A MEMORY AND A DISTRIBUTED COMPUTE ARRAY
    Publication number: 20210174848
    Abstract: An integrated circuit (IC) includes a plurality of dies. The IC includes a plurality of memory channel interfaces configured to communicate with a memory, wherein the plurality of memory channel interfaces are disposed within a first die of the plurality of dies. The IC may include a compute array distributed across the plurality of dies and a plurality of remote buffers distributed across the plurality of dies. The plurality of remote buffers are coupled to the plurality of memory channels and to the compute array. The IC further includes a controller configured to determine that each of the plurality of remote buffers has data stored therein and, in response, broadcast a read enable signal to each of the plurality of remote buffers initiating data transfers from the plurality of remote buffers to the compute array across the plurality of dies.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 10, 2021
    Applicant: Xilinx, Inc.
    Inventors: Xiaoqian Zhang, Ephrem C. Wu, David Berman
  • STRAP ATTACHMENT
    Publication number: 20210161268
    Abstract: A strap attachment device includes a strap connector configured to attach to a strap and a connecting plate secured on the surface of an article such as a bag or suitcase. The strap connector includes a connector post configured to removably engage and be secured by a locking member located beneath the connecting plate. The locking member is biased into a closed position by a mechanical biasing means, such as a spring. The connector post may include a flanged end configured to partially disengage the locking member causing the flanged end to mate with and be secured by the locking member responsive to being inserted into the connecting plate. A pull tab is further disposed on a pull track within the connecting plate. A user can disengage the connector post from the locking member by moving the pull tab along the pull track.
    Type: Application
    Filed: February 9, 2021
    Publication date: June 3, 2021
    Inventors: Peter C. Wu, Paul V. Scicluna, Michael Greisser
  • PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COUNTERING CHEMOTHERAPY INDUCED CARDIOTOXICITY
    Publication number: 20210121436
    Abstract: This disclosure provides methods and pharmaceutical compositions for reducing or eliminating cardiotoxicity, particularly cardiotoxicity induced by a cancer treatment or other therapy. In some cases, the methods and compositions prevent or reduce cardiotoxicity caused by anthracycline treatment. The methods provided herein often comprise administering a protective agent such as myricetin, tricetin, robinetin, ficetin, vitexin, quercetin, dihydrorobinetin, kaempferol, 7,3?,4?,5?-tetrahydroxyflavone, and myricitrin in conjunction with the administration of a cancer drug or other treatment. They may comprise administering a protective agent in combination with dexrazoxane. The compositions provided herein include co-formulations of a protective agent with a different protective agent or with a cancer treatment (e.g., anthracycline drug).
    Type: Application
    Filed: October 6, 2020
    Publication date: April 29, 2021
    Applicants: Auransa Inc., SCT II LLC
    Inventors: Christopher G. ARMSTRONG, Kevin J. KIM, Lisa Maria Lucia PHAM, Eunhye PARK, Zhong ZHONG, Guanyi HUANG, Joseph C. WU, Sidney Paul ELMER, Viwat VISUTHIKRAISEE, Eithon Michael G. CADAG, Thomas Bernard FREEMAN, Pek Yee LUM
  • MANUFACTURING METHOD OF CONTINUOUS TRANSPARENT POLYIMIDE FILM FOR DISPLAY
    Publication number: 20210102034
    Abstract: A manufacturing method of a continuous transparent polyimide film for a display includes the following steps providing a roll-to-roll polyimide film; providing a polyimide precursor, which is coated on the polyimide film; and baking the polyimide precursor at a baking temperature that is at least 20° C. higher than a glass transition temperature of the transparent polyimide film, such that the transparent polyimide film has an optical transmittance of greater than 85%, a chromaticity (b*) of less than 2, and a standard deviation of three axial refractive indices of the transparent polyimide film is less than 0.0012. Thus, the transparent polyimide film with reduced light leakage can be obtained.
    Type: Application
    Filed: September 2, 2020
    Publication date: April 8, 2021
    Inventors: YI-HSUEH HO, YUN-HSIANG CHANG, YI-CHIA HUANG, PAUL S.C. WU
  • ACCESSORY INSERT MODULES WITH MAGNETIC ALIGNMENT COMPONENTS
    Publication number: 20210099031
    Abstract: A magnetic alignment system can include a primary annular magnetic alignment component and a secondary annular magnetic alignment component. The primary alignment component can include an inner annular region having a first magnetic orientation, an outer annular region having a second magnetic orientation opposite to the first magnetic orientation, and a non-magnetized central annular region disposed between the primary inner annular region and the primary outer annular region. The secondary alignment component can have a magnetic orientation with a radial component. Additional features, such as a rotational magnetic alignment component and/or an NFC coil and circuitry can be included.
    Type: Application
    Filed: September 22, 2020
    Publication date: April 1, 2021
    Applicant: Apple Inc.
    Inventors: Eric S. Jol, Karl Ruben F. Larsson, Aaron A. Oro, Timothy J. Rasmussen, Christopher S. Graham, James C. Wu, Demetrios B. Karanikos, Miranda L. Daly, Paul J. Thompson, Joshua A. Mendoza
  • Briefcase
    Patent number: D922068
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: June 15, 2021
    Assignee: TUMI, INC.
    Inventor: Peter C. Wu
  • Luggage
    Patent number: D929734
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: September 7, 2021
    Assignee: TUMI, INC.
    Inventor: Peter C. Wu