Abstract: A method, apparatus, system for managing a maintenance for a component in a vehicle. Sensor data is received for the vehicle. Target parameters are predicted using behavior machine learning models trained using first training data to predict the target parameters for a normal behavior of the component operating in a tolerance, wherein the target parameters characterize behavior of the component. Prediction metrics are determined from predicted values for the target parameters predicted by behavior machine learning models and actual values for the target parameters. Whether the component will fall out of the tolerance after a time period is predicted using the prediction metrics and a maintenance machine learning model trained using second training data to predict whether the maintenance is needed for the component, wherein the second training data comprises historical prediction metrics determined for the target parameters.

Abstract: A system for determining risky events includes an input interface and a processor. The input interface is for receiving sensor data on environmental conditions. The processor is for determining whether the environmental conditions indicate an increase in event probability and, in the event that environmental conditions indicate the increase in the event probability, adjusting an event detection threshold.

Abstract: A manifold for control of fluid and/or vapor flow between a container and a pump cartridge for a compounder system is provided. One or more manifolds may be disposed in a magazine configured to secure and align the manifolds with a plurality of ports in the cartridge. Each manifold may include a needle having forward and rear openings to a central bore. A needle housing may include a slot configured to receive a push rod for actuating the needle forward and backward. In a forward, engaged position, the openings in the needle may be disposed on opposite sides of a sealing member of the manifold to form a fluid pathway through the manifold. In a rearward, disengaged position, both the forward and rear openings in the needle may be disposed on the same side of the sealing member to prevent fluid and vapor from flowing through the manifold.

Abstract: Described are methods for processing microelectronic device substrates by a lapping step, e.g., a final lapping step, wherein the step includes the use of an elastomeric pressure-sensitive adhesive to secure the microelectronic device substrate to a carrier that holds the substrate to a surface of the carrier during the lapping step, and wherein the pressure-sensitive adhesive can be a non-polysilicone based adhesive having mechanical properties that include a tan delta that is below about 0.2.

Abstract: In one exemplary embodiment, a flow path component assembly includes a support structure having an axial portion and a radial portion and an outer portion arranged between the support structure. The outer portion defines a gap between the outer portion and the axial portion of the support structure. A flange is positioned relative to the gap.

Abstract: Needleless connectors are described herein. A needleless connector includes a body, a valve element at least partially disposed within the body, and a base. The valve element includes a cylindrical portion having an outwardly extending flange at a distal end. The flange has a bottom surface with an outer area and an inner area. The base includes a rim having a top surface that is in contact with an outer area of the flange of the valve element, the rim defining a recess with a bottom surface separated from the top surface of the rim, and at least one support member having a top surface spaced apart from the top surface of the rim and configured to resist deformation of the flange toward the recess.

Abstract: Methods, computer program products, and systems for generating adaptive temporal-based prediction scores representative of a likelihood of non-compliance with respect to a recommendation associated with a user identifier. One or more prediction-based actions can be executed based on the adaptive temporal-based prediction score satisfying a threshold.

Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.

Abstract: Examples of the disclosed systems and methods may provide for improved and more realistic rendering of virtual characters and a more realistic interaction between a user and virtual characters. For example, the systems and methods describe techniques for mathematically generating a map used for animating facial expressions in a multidimensional animation blendspace. As another example, the systems and methods describe a transition system for dynamically transitioning facial expressions across a face of the virtual character. As another example, realistic physical movements can be added to a virtual character's facial expressions to provide interactivity with other virtual characters.

Abstract: Embodiments of the present disclosure may generally relate to systems, apparatus, and/or processes directed to a manufacturing process flow for packages that include one or more glass layers that include patterning features, such as electrically conductive traces, RDLs, and vias within the packages. In embodiments, a package may include a glass layer with a first side and a second side opposite the first side, where the glass layer is a dielectric layer. The package may include another layer coupled with the first side of the glass layer, and a pattern on the second side of the glass layer to receive a deposited material in at least a portion of the pattern.

Abstract: A control system for an automated singulation system is provided. The control system detects a presence of a first item on a first conveyor and detects a presence of a second item on a second conveyor while the first item is present on the first conveyor. The second conveyor transfers items onto the first conveyor and is at a lower height than the second conveyor. The first conveyor is oriented perpendicularly with respect to the second conveyor. In response to detecting the presence of the second item, a location of the first item along a length of the first conveyor is determined. The first conveyor and the second conveyor are controlled based at least on the location of the first item.

Abstract: The field of materials and manufacturing methods involving single or multi-solvent, excipient and polymer-free drug coating formulations for production of microsphere coated drug delivery techniques.

Abstract: A computer-implemented method, a computer system and a computer program product manage network throughput based on weather conditions. The method includes identifying a weather condition from a weather forecast. The weather condition includes a geographic area and a time period. The method also includes collecting historical data associated with the network. The historical data includes the network throughput during a past event. The method further includes determining that the weather condition will lower the network throughput below a threshold based on the network throughput during the past event. Lastly, the method includes dynamically creating software application containers on a server at a time prior to the time period of the weather condition. The software application containers are accessed by a user computing device within the geographic area.

Abstract: Described are methods for processing microelectronic device substrates by a lapping step, e.g., a final lapping step, wherein the step includes the use of an elastomeric pressure-sensitive adhesive to secure the microelectronic device substrate to a carrier that holds the substrate to a surface of the carrier during the lapping step, and wherein the pressure-sensitive adhesive can be a non-polysilicone based adhesive having mechanical properties that include a tan delta that is below about 0.2.

Abstract: The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that pro mote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.

Abstract: A footwear includes a shoe sole, a shoe upper member coupled on the shoe sole, and a toe guider device which includes first and second spacers. Bottom ends of the first and second toe spacers are retained by the shoe sole while top ends of the first and second toe spacers are retained by the shoe upper. The first toe spacer is retained for being worn between first and second toes of a wearer. The second toe spacer is retained for being worn between second and third toes of the wearer.

Abstract: Needleless connectors are described herein. A needleless connector includes a body, a valve element at least partially disposed within the body, and a base. The valve element includes a cylindrical portion having an outwardly extending flange at a distal end. The flange has a bottom surface with an outer area and an inner area. The base includes a rim having a top surface that is in contact with an outer area of the flange of the valve element, the rim defining a recess with a bottom surface separated from the top surface of the rim, and at least one support member having a top surface spaced apart from the top surface of the rim and configured to resist deformation of the flange toward the recess.

Abstract: One aspect of the disclosure relates to an extramedullary distraction and compression system. The extramedullary distraction system includes: a housing configured to be attached to a bone at a first location, the housing having a magnet and a lead screw positioned therein, wherein the lead screw is coupled to the magnet such that rotation of the magnet causes rotation of the lead screw, at least one retainer clip disposed around the lead screw; a rod configured to be attached to the bone at a second location and configured to interact with the lead screw such that, upon rotation of the lead screw, the rod distracts or contracts relative to the housing.

Abstract: An ultrasound probe with antimicrobial surface activity includes a housing, wherein the housing has an antimicrobial compound present at an exterior surface of the probe housing in sufficient concentration to provide antimicrobial activity with microbes that contact the exterior surface of the ultrasound probe. A plurality of antimicrobial compounds may be present at the exterior surface of the probe housing in sufficient concentration to provide antimicrobial activity. The antimicrobial compound may be an additive to a polymeric material from which the probe housing is manufactured. The antimicrobial compound may be present in an antimicrobial coating disposed on the exterior surface of the probe housing. The antimicrobial activity may provide log reductions in gram+ and gram? bacteria after 24 hours in the range from 3 to 7.

Abstract: A fluid transfer device for use with a peripheral intravenous catheter (PIVC) including an introducer body having a proximal end and a distal end, and a flow tube at least partially housed within the introducer body, wherein the flow tube is configured to be selectively extendable from the introducer body. The fluid transfer device also includes a lever lock coupled to the distal end of the introducer body, wherein the lever lock includes a lumen configured to allow the flow tube to pass therethrough, and wherein an effective length of the lever lock relative to the distal end of the introducer body is adjustable in order to accommodate use of the fluid transfer device with indwelling catheters of the PIVC having various lengths.