Abstract: In one exemplary embodiment, a flow path component assembly includes a support structure that is a unitary component having an axial portion and a radial portion and an outer portion arranged between the support structure and a flow path. The outer portion defines a gap between the outer portion and the support structure axial portion. A flange extends into the gap.

Abstract: In one exemplary embodiment, a flow path component assembly includes a support structure that is a unitary component having an axial portion and a radial portion and an outer portion arranged between the support structure and a flow path. The outer portion defines a gap between the outer portion and the support structure axial portion. A flange extends into the gap.

Abstract: In one exemplary embodiment, a combustor liner includes a first portion extending in a substantially axial direction and a second portion that extending in the substantially axial direction. A step connects the first portion and the second portion. The step is arranged at an angle to the second portion that is less than 90°. The step has a step height defined as a distance between the first portion and the second portion. The first portion, second portion, and step are formed as a unitary ceramic component. A slot extends through the step, and a ratio of a height of the slot to a height of the step is greater than 0.66.

Abstract: A system for moving a portion of a patient's body including a housing having a first cavity extending along a longitudinal axis, a first distraction rod having a proximal end and a distal end, the first distraction rod and the housing being telescopically displaceable with respect to each other along the longitudinal axis, the first distraction rod having a cavity extending along the longitudinal axis, a second distraction rod having a proximal end and a distal end and configured to be telescopically displaceable from within the second cavity along the longitudinal axis, and a drive system configured to move the first distraction rod in relation to the housing and to move the second distraction rod in relation to the first distraction rod.

Abstract: An apparatus for distributing a gas within a process chamber is disclosed. The apparatus has a body formed from a distribution portion surrounded by a coupling portion. A heater is disposed within the distribution portion to heat the body to an elevated temperature. A bridge extends between the coupling portion and the distribution portion. The bridge limits heat transfer between the distribution portion and the coupling portion.

Abstract: An airfoil includes an vane airfoil, which has a ceramic matrix composite airfoil section including an outer wall that defines an internal cavity. The vane airfoil has an associated temperature profile which defines at least one high temperature area and at least one low temperature area. The vane airfoil includes a first zone which is defined in a first radial extent and corresponds to the high temperature area of the temperature profile and a second zone defined in a second radial extent and corresponds to the low temperature area of the temperature profile. An insert is situated in the internal cavity. The insert includes a first zone defined in a first radial extent that is aligned with the first zone of the vane airfoil. The first zone includes a first plurality of cooling holes which are configured to provide a first cooling density. A second zone is defined in a second radial extent that is aligned with the second zone of the vane airfoil.

Abstract: A method of manufacturing an intraoral device (1) including: obtaining an impression of at least one row of a patient's teeth; transferring said impression into a processor; said processor communicating with a milling machine; milling a blank of a first material to form a cavity in said blank substantially corresponding to said impression, said cavity being milled to include an offset; said cavity with at least a second material and allowing said second material to cure; milling said second material to correspond to said impression; milling said first material to obtain a device shape; cleaning said device (1); and wherein said first and second materials are comparatively hard and soft.

Abstract: The present disclosure is directed toward systems and methods for managing a digital survey over voice-capable devices. In particular, the systems and methods described herein create a digital survey question from a verbal input. Additionally, the systems and methods described herein provide the digital survey question to respondents by way of voice-capable devices. The systems and methods also receive verbal survey responses, generate survey results from the verbal responses, and provide the survey results to a survey administrator.

Abstract: A gas turbine engine includes one of a turbine section and a compressor section having multiple stages. At least one of the stages defines an outer diameter comprised of a plurality of circumferentially arranged blade outer air seals. Each blade outer air seal is spaced from each adjacent blade outer air seal in the plurality of circumferentially arranged blade outer air seals via a mateface gap. The mateface gap is oblique to a radius of the gas turbine engine, such that air entering the mateface gap is directed to an inner diameter surface of at least one of the blade outer air seals in the plurality of blade outer air seals.

Abstract: The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.

Abstract: A gas turbine engine includes a ceramic wall for bounding an engine core gas path. The ceramic wall has a ceramic wall first side that faces the engine core gas path and a ceramic wall second side that faces away from the engine core gas path. There is a metallic wall adjacent the ceramic wall second side. The metallic wall has a metallic wall first side that faces the ceramic wall and a metallic wall second side that faces away from the ceramic wall. The metallic wall and the ceramic wall are spaced apart such that there is a channel there between. There is a seal on the ceramic wall second side, and the metallic wall has at least one cooling hole adjacent the seal for emitting cooling air to cool the seal.

Abstract: Methods, apparatuses and systems are described that are capable of simultaneously determining the presence, identities or levels of multiple analytes present in a single sample, by carrying out steps including denaturation, normalization, extraction, mixed-mode liquid chromatography and mass spectrometry, whereby the presence, identities or levels of analytes in the single sample are determined.

Abstract: In some embodiments, the semiconductor process apparatus comprises a conductive support comprising mesh, a conductive shaft comprising a conductive rod, and a plurality of connection elements. The plurality of connection elements are coupled to the mesh in parallel and are connected to the rod at a single junction. The plurality of connection elements help spread RF current, reducing localized heating in the substrate, resulting in a more uniform film deposition. Additionally, using connection elements that are merged and coupled to a single RF rod allow for the rod to be made of materials that can conduct RF current at lower temperatures.

Abstract: A vane arc segment includes an airfoil piece that defines first and second platforms and a hollow airfoil section that has an internal cavity and extends between the first and second platforms. The first platform defines a gaspath side, a non-gaspath side, and a flange that projects from the non-gaspath side. Support hardware supports the airfoil piece via the flange. There is a conformal thermal insulation blanket disposed on the flange.

Abstract: A gas turbine engine component according to an example of the present disclosure includes a wall extending in a thickness direction between first and second wall surfaces. The first wall surface bounds an internal cavity. The wall includes a plurality of cooling passages. Each of the cooling passages extend in a first direction between an inlet port and an outlet port coupled to a respective diffuser, and the inlet port coupled to the internal cavity along the first wall surface. Sidewalls of adjacent diffusers are conjoined to establish a common diffuser region interconnecting the diffusers and a common outlet along the second wall surface. A method of cooling a gas turbine engine component is also disclosed.

Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.

Abstract: A method, apparatus and system for training an embedding space for content comprehension and response includes, for each layer of a hierarchical taxonomy having at least two layers including respective words resulting in layers of varying complexity, determining a set of words associated with a layer of the hierarchical taxonomy, determining a question answer pair based on a question generated using at least one word of the set of words and at least one content domain, determining a vector representation for the generated question and for content related to the at least one content domain of the question answer pair, and embedding the question vector representation and the content vector representations into a common embedding space where vector representations that are related, are closer in the embedding space than unrelated embedded vector representations. Requests for content can then be fulfilled using the trained, common embedding space.

Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.

Abstract: The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.

Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.