Abstract: A method for classifying multi-granularity breast cancer genes based on a double self-adaptive neighborhood radius includes large-scale gene locus data are read and normalized, and a data analysis is performed on the large-scale gene loci. An optimum value K is selected by adopting a combination of contour coefficients and a PCA dimensionality reduction visualization, and a model of information granulation is adjusted. A heuristic reduction algorithm is used to implement a multi-granularity attribute reduction of a self-adaptive neighborhood radius based on a cluster center distance and a multi-granularity attribute reduction of a neighborhood radius based on an attribute inclusion degree, and big data for breast cancer genes are classified and predicted by adopting a machine learning classification algorithm based on a SVM support vector machine.

Abstract: Embodiments of this disclosure provide a display substrate and a display device. The display substrate includes: sub-pixels located on a base substrate; a first conductive layer located on one side of the base substrate, and including signal lines sequentially disposed in a first direction and extending towards a second direction, and signal line bulges and anode adaptor parts located on the same side of the signal line and disposed alternately; and anodes located between the first conductive layer and a pixel defining layer. Each anode includes an effective part exposed by a corresponding sub-pixel opening, the effective parts of at least part of the sub-pixels have overlapping regions with the signal line bulges and the anode adaptor parts in the second direction, and the second direction is perpendicular to the first direction.

Abstract: Environmental tracking systems and methods are disclosed. An environmental tracking system receives sensor data from the one or more sensors, such as camera(s) and Light Detection and Ranging (LIDAR) sensors. The system uses trained machine learning (ML) model(s) to detect, within the sensor data, representation(s) of at least a portion of a vehicle with a door that is at least partially open. Based on these representation(s), the system generates a boundary for the vehicle that includes the door and is sized based on the door being at least partially open. The system determines a route that avoids the boundary, for example by planning the route around the boundary or by planning to stop before intersecting with the boundary. In some examples, the sensors are sensors coupled to a second vehicle, and the second vehicle traverses the route.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.

Abstract: A photovoltaic power plant and a secondary frequency modulation control method therefor are disclosed. The photovoltaic power plant includes a photovoltaic power station and an active power control system, wherein the photovoltaic power station includes a photovoltaic array and a photovoltaic inverter, the photovoltaic inverter being used for converting direct-current electric energy generated by the photovoltaic array into alternating-current electric energy; and the active power control system is used for performing power allocation on the photovoltaic inverter based on a power control AGC instruction value when running data of the photovoltaic power plant meets a pre-set secondary frequency modulation condition, and adjusting an active power output from the photovoltaic inverter based on an AGC instruction value of the photovoltaic inverter subjected to power allocation. The photovoltaic power station can improve the accuracy of power control and the stability of a power system.

Abstract: A method and apparatus for limiting an RF alternating magnetic field in MRI. The method includes: measuring a perpendicular distance between a local coil placed on a scanned part of a patient and the center of a detection hole of a magnetic resonance (MR) scanner; based on the perpendicular distance, determining a deviation between the B1 field strength at the position of the local coil during an MR scan and the B1 field strength at the center of the detection hole; based on the deviation, computing a conversion coefficient for conversion between the B1 field strength at the position of the local coil and the B1 field strength at the center of the detection hole; based on the B1 field strength required when the surface temperature of the local coil is equal to a safe temperature upper limit and the conversion coefficient, computing a maximum permissible field strength of the B1 field at the center of the detection hole.

Abstract: Provided herein are DLL3 binding agents and chimeric antigen receptors (CARs) comprising a DLL3 binding molecule that specifically binds to DLL3; and immune cells comprising these DLL3-specific CARs, e.g., CAR-T cells. Also provided are methods of making and using DLL3-specific CARs, and immune cells comprising DLL3-specific CARs.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.

Abstract: Provided herein are mammalian cells comprising a first exogenous nucleic acid encoding a DNAse protein and a second exogenous nucleic acid encoding another DNAse protein, such as DNASE1 protein and DNASE1L3 protein, that have improved properties, including the ability to degrades extracellular chromatin and remove Neutrophil Extracellular Traps (NETs). Use of these cells, including the use in the treatment of a subject in need thereof, is also contemplated.

Abstract: A display module (10) includes: a display panel (12) and a circuit board (14) coupled to the display panel (12). The display panel (12) includes a driving chip (122) and a display unit (124); and the circuit board (14) includes a first filter element (142), wherein the first filter element (142) is coupled to the driving chip (122) and the display unit (124), and a direct current signal output by the driving chip (122) is filtered by the first filter element (142) and then transmitted to the display unit (124). The present disclosure also provides a display apparatus (1100).

Abstract: Microscopic analysis of a sample includes a fluorescent dye disposed within the sample. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. An optical source generates a probe beam directed to impinge on the sample. A detector detects fluorescent emissions from the sample when the probe beam impinges on the sample. A data acquisition and processing system acquires and processes the detected fluorescent emissions from the sample to: (i) generate a signal indicative of infrared absorption by the sample, (ii) generate a signal indicative of temperature in the sample based on the signal indicative of infrared absorption by the sample, (iii) generate an image of the sample using the signal indicative of temperature in the sample.

Abstract: A cleaning nozzle includes an outer housing having a central axis and an inner surface that defines an outer housing interior. An inner housing resides within the outer housing interior along the central axis and has an inner surface that defines an inner flow channel. The inner flow channel supports flow of the cleaning fluid and has a converging taper and a flow disrupter element. The nozzle assembly may include an adapter that receives a front end of the nozzle and that also holds a ferrule that supports an optical fiber having an end face. The nozzle assembly allows the nozzle to direct a jet stream of cleaning fluid to the ferrule end face and the fiber end face. The flow disrupter causes the jet stream to have a time-varying direction that enhances the cleaning of the ferrule end face and the optical fiber end face.

Abstract: Systems and methods for detecting worsening cardiac conditions such as worsening heart failure events are described. A system may include sensor circuits to sense physiological signals and signal processors to generate from the physiological signals first and second signal metrics. The system may include a risk stratifier circuit to produce a cardiac risk indication. The system may use at least the first signal metric to generate a primary detection indication, and use at least the second signal metric and the risk indication to generate a secondary detection indication. The risk indication may be used to modulate the second signal metric. A detector circuit may detect the worsening cardiac event using the primary and secondary detection indications.

Abstract: The present disclosure provides a method and system for providing medical services to a user. The method may include acquiring first information of a medical process including a plurality of sub-processes to be allocated with medical resources. The method may also include obtaining second information on medical resources, and the second information may include available time slots and locations of the medical resources. The method may further include allocating the medical resources for the medical process based on the first information and the second information. The method may also include determining, for at least one sub-process of the plurality of sub-processes of the medical process, appointment information of the at least one sub-process based on at least a portion of the second information corresponding to the medical resource allocated to the at least one sub-process.

Abstract: The present disclosure relates to a method for evaluating and predicting a placenta-derived disease and a kit. Specifically, the invention of the present disclosure provides a method for detecting the methylation modification level of at least one DNA methylation modification difference locus or at least one DNA methylation haplotype in a given genomic position in a sample to be tested, a kit, and a corresponding detection system, which can be used for accurately screening, in vitro, whether a subject has a placenta-derived gestational disorder.

Abstract: An image sensor includes an image sensor pixel array having pixels. Each pixel includes a continuous active region having a first portion and a second portion extending from the first portion. A photodiode, a reset transistor, a drive transistor, and a select transistor are formed in and over the first portion. The photodiode and the reset transistor define a floating diffusion region therebetween. A switch transistor is formed in and over the second portion and includes a first source/drain region and a second source/drain region. The first source/drain region is included in the floating diffusion region. The second source/drain region interfaces a doped region formed in the second region. The pixel also includes a gate structure disposed directly over the doped region. By controlling the switch transistor, the pixel may operate in a high conversion gain mode or a low conversion gain mode to accommodate different illumination or exposure conditions.

Abstract: The present disclosure provides a method for assessing hot coal fallout propensity of burning cigarettes based on human behavior features of ash-tapping action. The method is characterized in that the method is accomplished through an apparatus for detecting hot coal fallout propensity based on human behavior features of ash-tapping action, which include behavior features of human action of tapping cigarette ash, features of holding a cigarette, and features of force applying process and other aspects. This method can provide objective and accurate test basis for evaluation of cigarette fallout performance.

Abstract: A display substrate and a display panel are disclosed. The display substrate includes a base substrate having an active area and a peripheral area surrounding the active area; a plurality of sub-pixels, in the active area; a plurality of first pins and a plurality of second pins located in the peripheral area; a plurality of first array test pins located between the plurality of first pins and the plurality of second pins and respectively electrically coupled to a plurality of array test signal lines; and a plurality of second array test pins located between the plurality of first pins and the plurality of second pins and extending in a direction along a boundary of the active area, wherein the plurality of first array test pins are located on at least one side of the plurality of second array test pins in the direction along the boundary of the active area.

Abstract: The present disclosure provides a control method for a DC converter and a DC converter. the DC converter comprises a switching circuit, a sampling circuit, and a controller, the method comprising: acquiring a duty ratio of a Burst cycle according to an output reference signal and an output signal; acquiring a first number of switching cycles and a burst on time according to the duty ratio of the Burst cycle, a first preset value, and a switching period of the switching device; acquiring a Burst cycle value according to the burst on time and the duty ratio of the Burst cycle; and generating a driving signal according to the Burst cycle value, the first number of switching cycles, and the switching period.

Abstract: Various approaches for the integration and use of edge computing operations in satellite communication environments are discussed herein. For example, connectivity and computing approaches are discussed with reference to: identifying satellite coverage and compute operations available in low earth orbit (LEO) satellites, establishing connection streams via LEO satellite networks, identifying and implementing geofences for LEO satellites, coordinating and planning data transfers across ephemeral satellite connected devices, service orchestration via LEO satellites based on data cost, handover of compute and data operations in LEO satellite networks, and managing packet processing, among other aspects.