Abstract: The present disclosure relates to the technical field of biotechnology, in particular to carbonyl reductase mutant and its application. Specifically, the present disclosure provides a carbonyl reductase mutant for catalyzing the preparation of (R)-8-chloro-6-hydroxyoctanoic acid ethyl ester from 8-chloro-6-oxooctanoic acid ethyl ester. The mutant protein is a non natural protein and undergoes mutations in three core amino acids related to enzyme catalytic activity in the initial carbonyl reductase. The advantageous effect of the present disclosure is that the carbonyl reductase mutant provided by the present disclosure has the characteristic of efficiently catalyzing the preparation of the precursor substance (R)-8-chloro-6-hydroxyoctanoic acid from 8-chloro-6-oxooctanoic acid ethyl ester, and can efficiently catalyze the oxidation-reduction reaction of 8-chloro-6-oxooctanoic acid, with a product space-time yield of 99.9 g·L?1·h?1 or more.

Abstract: A method for unrolling and rolling a rollable screen. The method includes: starting a rollable screen motor in a case where a target gesture for a display screen meets a preset gesture; and determining a motion parameter of the rollable screen motor according to the target gesture, wherein the motion parameter is configured for indicate that the rollable screen is unrolled to a first preset state, or is closed to a second preset state.

Abstract: Provided are a cathode material for sodium-ion batteries, a preparation method therefor, and an application thereof, and the preparation method comprises the following steps: (1) mixing a nickel source, a manganese source, and a magnesium source to obtain a ternary salt solution, adding the ternary salt solution, a precipitating agent, a complexing agent, a boron source solution, and an organic additive to a reaction vessel in parallel flow, and performing a reaction to obtain a B-doped radially-packed hydroxide precursor; and (2) mixing the B-doped radially-packed hydroxide precursor obtained in step (1) with a sodium source, and performing sintering treatment to obtain the cathode material for sodium-ion batteries.

Abstract: A battery that cycles lithium ions includes a lithium metal negative electrode, a positive electrode, a porous separator disposed between opposing facing surfaces of the lithium metal negative electrode and the positive electrode, and a composite interlayer disposed on the facing surface of the lithium metal negative electrode, between the lithium metal negative electrode and the porous separator. The composite interlayer includes a polymer matrix phase and a lithium salt distributed phase embedded in and distributed throughout the polymer matrix phase. The lithium salt distributed phase constitutes, by weight, greater than or equal to about 10% and less than or equal to about 50% of the composite interlayer.

Abstract: Wireless communication methods for multicast/broadcast service (MBS) and apparatuses are disclosed. The method performed by a user equipment (UE) includes when the UE is interested in one or more multicast services/sessions or receives the one or more of multicast services/sessions, the UE is in a connected state or is indicated to enter the connected state, receiving, by the UE being in the connected state or being indicated to enter the connected state, a multicast configuration via a dedicated signaling, entering, by the UE, an inactive state when the UE receives the multicast configuration, and receiving, by the UE in the inactive state, the one or more of multicast services/sessions.

Abstract: Provided herein are adhesive compositions comprising: 1) at least one adhesive of an alcohol-functionalized acrylic adhesive, an alcohol-functionalized silicone adhesive, a carboxyl-functionalized acrylic adhesive, and a carboxyl-functionalized silicone adhesive, 2) at least one phase-separated hydrophilic material, and 3) at least one bioactive compound. At least one bioactive compound may comprise an antimicrobial agent. The adhesive compositions can quickly release an antimicrobial agent and cause the rapid onset of antimicrobial effects. Also provided are adhesive products and methods using the disclosed adhesive composition.

Abstract: Provided herein are methods for producing neuroectoderm and retinal progenitor cells from pluripotent stem cells, and compositions of retinal progenitor cells produced thereby.

Abstract: Embodiments of the present disclosure provide a method, an apparatus, an electronic device and a storage medium for effect processing. The method comprises: in response to an effect triggering operation, obtaining a first image and a second image, wherein the first image comprises a target object, and the second image is displayed on an upper layer of the first image; determining a target image region in the second image based on the capture distance and an object position of the target object in the case where a capture distance between the target object and a capture apparatus satisfies a first distance condition; displaying at least part of an image content in the first image in the target image region to acquire an effect image.

Abstract: Disclosed are a SERS nano-particle, a preparation method therefor, and an application thereof to a method for distinguishing CTCs from WBCs. The SERS nano-particle are formed by core magnetic particles, noble metal nano-particles, Raman signal molecules, hydrophilic molecules and target molecules. A method for distinguishing CTCs from WBCs comprises: enabling a SERS nano-particle to make contact with a to-be-detected solution containing CTCs and/or WBCs; performing incubation; then detecting SERS signal intensity of a cell combined with the SERS nano-particle; setting SERS signal intensity threshold; if SERS signal intensity of the cell combined with the SERS nano-particle exceeds SERS signal intensity threshold, determining the cell as CTS; otherwise, determining the cell as WBC. A ROC curve is used for the first time to assist the SERS technique in distinguishing CTCs from WBCs.

Abstract: The present disclosure discloses an earphone core having a frame with a receiving space and a magnet unit and a vibration unit both fixed on the frame. The magnet unit includes a yoke and the first magnet. The vibration unit includes a diaphragm and a coil fixed on the diaphragm; a MEMS tweeter for providing high frequency sound is mounted on the first magnet the MEMS tweeter, the coil and the diaphragm are coaxially arranged along a vibration direction of the diaphragm. An axial height of the earphone core is effectively reduced, thereby saving its occupied space when applied in TWS earphone products.

Abstract: The present disclosure provides a baby carrier including a base; a leg section fixedly connected to the base; a backrest section pivotably connected to the base; and a guider configured for passage of a seat belt. The guider includes a first guider arranged in the leg section and a second guider arranged in the backrest section. The baby carrier according to the present disclosure can be securely bound by the seat belt and can be stabilized against a backrest of a vehicle seat.

Abstract: Provided are a method and an apparatus for implementing batch extraction of human anatomical feature parameters. The method includes: obtaining a to-be-measured sample; generating an average model; calculating a point correspondence of a spatial location formed by the average model and each to-be-measured sample; measuring each to-be-measured sample on the average model; and outputting feature parameter data of each to-be-measured sample in batch. Calculation time is reduced by combining feature point extraction with affine transformation, and corresponding points are calculated through a non-rigid registration method to achieve batch and quick measurement.

Abstract: Provided are a T-shaped reamed pile, a composite foundation, and a construction method for the composite foundation, relating to the technical field of civil engineering. The composite foundation is composed of a T-shaped reamed pile, soil between piles, and a cushion layer. The T-shaped reamed pile is composed of a core pile, a reamed body surrounding the outside of the core pile. A depth of the core pile is not lower than that of the reamed body, the reamed body includes an upper reamed body, and a lower reamed body, and a diameter of the upper reamed body is larger than that of the lower reamed body. The core pile is a precast pile, the reamed body is a cast-in-place reamed body, and the cushion layer is a sand-gravel cushion layer, or a reinforced cement-soil cushion layer.

Abstract: An integrated circuit includes a first region including a first set of transistors that include a first set of active regions having a first threshold voltage, the first set of transistors in a first portion of a level shifter circuit, the first portion of the level shifter circuit being coupled to a first voltage supply. The integrated circuit further includes a second region adjacent to the first region. The second region includes a second set of transistors that include a second set of active regions having a second threshold voltage different from the first threshold voltage, and the second set of transistors being in a second portion of the level shifter circuit.

Abstract: A novel general method for eliminating interference in both electrical and magnetic measurement systems is disclosed in this invention. The method applies to both electro and magnetic measurements using differential amplifiers, wherein the common-mode signal is extracted to serve as an interference template after being amplified and digitally sampled along with the differential signals. The method involves identifying matching template components within the signal and subtracting them to eliminate interference and improve the signal-to-noise ratio. For magnetic signal detection sensors using gradient coil structures, the symmetric point is grounded so that the mixed signal which contains the common-mode components representing interference and measurement signal are output at the two signal terminals.

Abstract: Presented are systems and methods for user equipment location verification. A first network node may perform location verification of a wireless communication device. Whether to release a connection with the wireless communication device can be determined by a second network node.

Abstract: A method comprises performing a pattern recognition process to determine a geometry of a superconducting quantum device comprising one or more Josephson junctions, determining, based on the geometry determined by the pattern recognition process, a laser beam illumination pattern for laser annealing the one or more Josephson junctions of the superconducting quantum device, and configuring a laser microscope to generate the laser beam illumination pattern.

Abstract: Provided is a system of generating multi-style learning tutorials based on learning preference evaluation. The system dynamically explores preferences of learners in a learning process from a time dimension through a proposed deep reinforcement learning model, so that a deep reinforcement learning agent can accurately express learning behavior features of learners and realize the personalized and accurate construction of course tutorials. At the same time, using an internal knowledge base and an external knowledge base as resource support, a multi-modal knowledge map with a plurality of definition relationships is designed to overcome the limitations of construction of a course tutorial method.

Abstract: A user equipment including a transceiver and a processor is disclosed. The processor is configured to determine a sidelink control information (SCI) format payload size based on resource pool configuration for the UE for inter-UE coordination with a second UE. The processor is configured to determine, based on the determined SCI format payload size, an SCI format including a number of message elements identifying attributes of a number of resources being used by the UE over a predetermined time period. The processor is configured to encode and transmit, to the second UE, the SCI format for the IUC for resource selection by the second UE.

Abstract: An electro-optic modulator is provided, including: a light splitting element; a light combining element; a first waveguide arm and a second waveguide arm that are arranged in parallel and are connected between the light splitting element and the light combining element; and a first ground electrode, a first signal electrode, a second ground electrode, a second signal electrode, and a third ground electrode that are arranged in sequence, where the first waveguide arm is located between the first ground electrode and the first signal electrode, the second waveguide arm is located between the second ground electrode and the second signal electrode, and the first signal electrode and the second signal electrode are configured to receive differential signals. A technical solution of an embodiment of the present disclosure can improve working performance of the electro-optic modulator.