Abstract: A method that includes selectively positioning an ablation catheter system at a treatment site comprising cardiac tissue, ablating cardiac tissue at the treatment site with the ablation catheter system using a power setting of approximately 90 W applied to tissue for approximately four (4) seconds to achieve a target electrode temperature, and achieving approximately zero incidence of steam pop occurrence in both left and right atrial ablations and complete pulmonary vein isolation, by the ablation catheter system, for all patients of a predetermined patient population suffering from paroxysmal atrial fibrillation (PAF).

Abstract: The present invention relates to an organic matter biodigester comprising a tank that has an organic matter inlet, a first connection arranged in an upper portion of the tank and a second connection arranged in the lower portion of the tank. Furthermore, said tank also has a biogas outlet and a lower surface configured to rest on a support surface. Furthermore, the lower portion of the tank is at a shorter distance from the support surface compared to the upper portion of the tank. Said organic matter biodigester also comprises a manual pump with a pump inlet connected in the second connection, and a pump outlet connected in the first connection of the tank. The pump is configured to recirculate the organic matter inside the tank from the second connection towards the first connection; and a porous layer arranged inside the tank.

Abstract: The present disclosure provides, inter alia, methods for treating neurodegenerative disease including Alzheimer's disease. Methods for restoring retromer complex function in a subject, methods for determining the progression of a neurodegenerative disease in a subject, and in vivo methods for identifying a DNA-binding profile of a dimeric transcription factor complex such as the retromer complex are also provided. Further provided are methods for restoring amyloid precursor protein (APP) homeostasis in a subject in need thereof, methods for restoring tau metabolism in a subject in need thereof, compositions and methods for preventing CREB3L2-ATF4 heterodimerization in a subject using such compositions, and methods for rescuing AP42-induced neuronal cell death in a subject using such compositions.

Abstract: A detection system (10) for hazard detection is provided. The detection system (10) includes a control loop (16); an addressable base unit (18) connected to the control loop (16), the base unit (18) including a first near-field communication module (22) storing a unit address; and a mounting unit (20) removably coupled to the base unit (18), the mounting unit (20) including a second near-field communication module (24) operable to read the unit address from the first near-field communication module (22) and store the unit address so that the mounting unit (20) is thereby addressable via the control loop (16).

Abstract: The present invention relates to novel esterases, more particularly to esterase variants having improved activity and/or improved thermostability compared to the parent esterase of SEQ ID NO:1 or SEQ ID NO:2 and the uses thereof for degrading polyester containing material, such as plastic products. The esterases of the invention are particularly suited to degrade polyethylene terephthalate, and material containing polyethylene terephthalate.

Abstract: A vehicular vision system includes a camera disposed at a vehicle and an electronic control unit (ECU) disposed at the vehicle remote from the camera. The ECU links to a vehicle network bus of the vehicle. The camera is connected to the ECU via an image data transmission line, which includes (i) a power-over-coaxial image data transmission line or (ii) a power-over-ethernet image data transmission line. The image data transmission line (i) transmits image data captured by the camera to the ECU and (ii) delivers electrical power from the ECU to the camera and (iii) communicates a control signal from the ECU to the camera. Captured image data is processed at the ECU for at least one driver assistance system of the vehicle. Filtering circuitry that filters electrical noise arising at least from delivery of electrical power via the image data transmission line from the ECU to the vehicular camera.

Abstract: Provided is a plasma processing method and device capable of controlling the etching mask shape during a single-step process that etches a target material disposed below the etching mask. The plasma processing method includes performing selective deposition on the etching mask in separate phases, which are controlled via a periodic bias voltage signal. By tuning the bias voltage power, duration and timing, the mask height and width can be controlled and stabilized while etching on the substrate proceeds. Thus, the present method provides an etching process that allows fine control of the etching mask shape for small pattern sizes and provides high etching selectivity through deposition.

Abstract: In some embodiments, a method receives a plurality of pull notification options at an application. The method determines whether to perform a ranking of the plurality of pull notification options at the application. When the ranking is be performed at the application: ranking the plurality of pull notification options; and outputting the plurality of pull notification options for display on the application based on the ranking. A pull notification option in the plurality of pull notification options is associated with information to cause an associated contact option to be contacted upon selection of the pull notification option. When the ranking is not to be performed by the application, the method outputs the plurality of pull notification options for display on the application.

Abstract: Techniques are described for distributed storage and retrieval of data by a defined computing system that includes a plurality of computing devices arranged in a network topology. The computing system stores two or more data blocks of a data set across two or more computing devices of the computing system. Each data block comprises at least one fragment of the data set and metadata including a data set identifier. The storage locations of the data blocks are determined based on messages exchanged among the plurality of computing devices, and may only be known by the computing devices within the computing system. After receipt of a request to access the data set, the two or more computing devices retrieve the two or more data blocks based on the data set identifier, and the computing system sends the two or more data blocks to a requesting device external to the computing system.

Abstract: Methods and systems are described for reducing interference on radio units from passive intermodulation (PIM) distortion. Base station radio units can have multiple antennas, each receiving and sending communications over various frequencies. Embodiments under the present disclosure can identify the source of PIM and then reduce power of the aggressor downlink carriers on the impacted antennas. This can reduce the PIM that desensitizes the uplink receivers.

Abstract: Disclosed herein are pharmaceutical agents and compositions that activate integrin heterodimers that contain beta-1 integrin protein that specifically bind laminin protein. Such agents and compositions are useful for treating diseases related to muscle malfunction, including muscular dystrophies.

Abstract: A composition contains filler particles dispersed in a matrix material, wherein the matrix material contains: (a) 0.01 to 1.50 weight-percent of a first polyorganosiloxane, wherein first polyorganosiloxane is a linear polyorganosiloxane with an average of 2 or more carboxylic acid groups per molecule; and (b) 5 to 30 weight-percent of a second polyorganosiloxane that is free of carboxylic acid groups, wherein the second polyorganosiloxane is a liquid at 25 degrees Celsius and 101 megaPascals pressure; wherein the filler particles are present at a concentration in a range of 15 to less than 78 volume-percent based on composition volume and weight-percent values are relative to weight of the composition and wherein the composition is free of at least one of aliphatic diols and silicone polyethers.

Abstract: Systems and methods to automate global employment are disclosed. A method may include generating a decision tree comprising one or more nodes. The method may include receiving a selection related to an employment inquiry. The method may include receiving a selection of a geographical preference associated with the employment inquiry. The method may include modifying the decision tree such that the one or more nodes are limited to a subset of nodes related to the employment inquiry and the geographical preference. The method may include receiving a selection of a preferred node of the subset of nodes. The method may include modifying the decision tree such that the decision tree is limited to the preferred node and a corresponding at least one branch.

Abstract: The present invention relates to a system and a method for cutting steel sheets by means of a milling cutter. For this purpose, a milling station is provided which comprises a liquid-cooled milling head, a milling table equipped to accommodate the steel sheet by means of a vacuum suction device for immobilizing the steel sheet to be machined, and an extraction device for extracting milling chips.

Abstract: A method includes receiving with a controller, neurophysiology activity data; receiving with the controller, biometric data for the patient; identifying with the controller, one or more weighted components of the neurophysiology activity data; assigning with the controller, based on the biometric data for the patient, a weight to each of the one or more weighted components; determining with the controller, based on a trained algorithm applied to the one or more weighted components, whether to apply the DBS; and instructing application with the controller, based on the determination, the DBS.

Abstract: A method (200) for configuring a set of reflectors (120), wherein the set of configurable reflectors are provided by a set of one or more intelligent reflecting surfaces, IRSs (105). The method includes determining (s202) a first set of one or more IRS configuration parameters, wherein the first set of IRS configuration parameters comprises at least one of; (a) a first link quality metric for a first link between a first CD and an access network node, wherein the first link comprises a first channel between the first CD and the set of one or more IRSs and a second channel between the set of one or more IRSs and the access network node; (b) a first quality-of-service, QoS, requirement for the first CD; or (c) a transmission status for the first CD.

Abstract: Soft and strong nonwoven web materials and methods of formation are described. In one embodiment, a nonwoven web may comprise a first and second outer regions of meltblown polymer fibers and absorbent fibers, the meltblown fibers formed of first and second polymer components where the second polymer component comprises greater than 0% and less than or equal to 20% by weight of a total polymeric material content of the meltblown polymer fibers, and a central region disposed between the first and second outer regions and comprising meltblown polymer fibers and absorbent fibers, the meltblown fibers being different than the meltblown polymer fibers of the first and second outer regions and not comprising the second polymer component.

Abstract: A sun gear for a mechanical gearbox of an aircraft turbomachine, the sun gear having an annular shape around an axis and including an internal annular part having at its internal periphery coupling grooves, an external annular part having at its external periphery at least one meshing tooth, the external part extending around the internal part, and an annular veil connecting the internal and external parts. At least one of the internal and external parts can include two independent rings, each having grooves or teeth, and the veil can have two annular branches connected respectively to the two rings.

Abstract: A system, network node and wireless device a provided. The wireless device receives, during an active time, downlink control information, DCI, having a predefined DCI format from the network node. The predefined DCI format includes at least one bit indicating that the DCI includes a go-to-sleep, GTS, indication. The wireless device is caused to enter a sleep state based at least in part on the GTS indication.

Abstract: A lidar receiver circuit for receiving optical signals using photodetectors to detect events or objects in the surrounding area, with a redundancy of receiver circuits for reducing failure probability, including a photodetector array for receiving optical signals and outputting a measurement signal, wherein the photodetectors are arranged as a two-dimensional matrix, a plurality of receiver circuits for receiving the measurement signal; a plurality of multiplexers, which are electrically arranged between the array and circuits and are connected thereto; wherein at least one of the multiplexers is connected to a column of photodetectors and at least two receiver circuits; each circuit is configured to receive and process the measurement signals of a column; a column of photodetectors is assigned to each receiver circuit by default; and the multiplexers connect a column to a receiver circuit other than the receiver circuit, which is assigned to the column of photodetectors by default.