Abstract: The present invention relates to the use of imaging for non-invasive and non-contact measurement of respiration rates and body temperature. The invention uses a combination of visible imaging, thermal imaging, and machine learning to monitor respiration rate and body temperature. One of the embodiments of the invention allows the invention to be mounted on an articulating arm for use in hospital settings. Another embodiment of the invention allows the invention to be easily portable for use in mobile applications. Further embodiments allow the system to be used remotely making it very applicable for use in isolation or for remote locations.

Abstract: Tropomyosin-related kinase inhibitors (Trk inhibitors) are small molecule compounds useful in the treatment of disease. Trk inhibitors can be used as pharmaceutical agents and in pharmaceutical compositions. Trk inhibitors are useful in the treatment of inflammatory diseases, autoimmune disease, defects of bone metabolism and/or cancer, and are particularly useful in the treatment of osteoarthritis (OA), pain, and pain associated with OA. Trk inhibitors are also useful for inhibiting tropomyosin-related kinase A (TrkA), tropomyosin-related kinase B (TrkB), tropomyosin-related kinase C (TrkC), and/or c-FMS (the cellular receptor for colony stimulating factor-1 (CSF-1)).

Abstract: The present invention relates to methods of using new doses of dulaglutide and compositions containing such higher doses of dulaglutide

Abstract: A system for fastening a tension rod of a grain tank of an agricultural vehicle to a frame of the agricultural vehicle to which the grain tank is mounted. The tension rod includes an elongated body extending between a first connection end that is configured to be connected either directly or indirectly to the grain tank, and a second connection end including openings for respectively receiving fasteners. A first member is either configured to be mounted to the frame or associated with the frame. The first member includes (i) openings for respectively receiving the fasteners, and (ii) a first non-planar mounting surface. A second member includes (i) openings for respectively receiving the fasteners and (ii) a second non-planar mounting surface that is configured to be directly engaged with the first non-planar mounting surface to limit relative motion between the tension rod and the frame in an assembled state.

Abstract: Systems, devices, methods, and techniques are described for using evoked compound action potential (ECAP) signals to determine an implant location for a lead. An example method includes receiving first information representative of a first evoked compound action potential (ECAP) signal sensed in response to a first control stimulus delivered to a first location adjacent to a spinal cord of a patient. The method also includes receiving, second information representative of a second ECAP signal in response to a second control stimulus delivered to a second location adjacent to the spinal cord of the patient. Additionally, the method includes outputting a first indication of the first information representative of the first ECAP signal and a second indication of the second information representative of the second ECAP signal.

Abstract: Systems and methods for enabling various devices to remotely interact with cloud-based client applications are provided. A method comprises receiving a first request from a first client device of a user to initiate an interactive session with a cloud-based client application, reserving an application engine for executing the cloud-based client application remotely from the first client device, receiving interaction data from the first client device as the user engages with a first media data associated with the cloud-based client application, modifying the cloud-based client application executing within the application engine that is reserved based on the interaction data received from the first client device, receiving a second request from the first client device to end the interactive session with the cloud-based client application that is modified, and deallocating the application engine that is reserved, wherein the application engine that is reserved is delinked from the first client device.

Abstract: A modular housing system includes a plurality of hollow steel section beam members of multiple standard lengths. Each hollow steel section beam member is designed to be coupled to at least one other hollow steel section beam member wherein the hollow steel beam members and are designed to form a rectangular frame assembly. The system includes at least four hub members designed to connect rectangular frame assemblies horizontally and vertically. Hub members couple multiple rectangular frame assemblies horizontally and solid tension rod members couple multiple rectangular frame assemblies vertically. Siding and roofing members may be preinstalled within a factory environment.

Abstract: A handheld ophthalmic device configured to perform various optical diagnostic tests to determine the health of a subject's eye. The handheld ophthalmic device is configured to be attached to a smartphone, a cell phone or an electronic tablet. The smartphone, a cell phone or an electronic tablet can be used to view images obtained by the handheld ophthalmic device and to transmit data and images obtained by the handheld ophthalmic device to an ophthalmologist located remotely.

Abstract: Briefly, the invention relates to a surgical tool and method for forming a pilot bore by inserting a guide wire into bone. More particularly, the device includes a cannulated hand grip and driving tool used for the rotation of a bone or pedicle screw into bone. The rear portion of the hand grip includes a slide assembly that is suited to grip a guide wire. The slide assembly includes a user adjustable stop to control the sliding movement of the guide wire. The rear surface of the slide is constructed to be impacted with a hammer or similar device, whereby the stop prevents the guide wire from penetrating the bone further than desired. A jack member is included to allow the wire to be precisely retracted.

Abstract: A cleat assembly for a shoe comprising an anchor for anchoring to the shoe, a cleat, a first biasing member circumscribing the anchor and engaged with the cleat, and a second biasing member biasing the first biasing member. The second biasing member can directly engage the first biasing member or a bushing that circumscribes the anchor. So constructed, the cleat assembly provides multiple degrees of freedom. That is, the cleat assembly provides effective axial shock absorbance coupled with 360º tilting of the cleat for enhancing a user's ability to suddenly change direction when wearing a shoe equipped with the cleat assembly, thereby minimizing stress and impact on muscles, joints and ligaments and enhancing the performance of athletes wearing such shoes.

Abstract: The present invention relates to a device and system for fixation of intra-articular and extra-articular fractures and non-unions of small bones and other small bone fragments, and more particularly to a threaded nail with a robust length and a trailing end with a cutting tip and longitudinal cutting flutes and a stepped diameter with cutting flutes at the transition point, and an optional cannulation along the central longitudinal axis of the nail.

Abstract: A bending apparatus for forming a helical strip of material. The bending apparatus comprises at least one bending head and is arranged to deform a strip of material into a helical form by applying a stress to a ridge running longitudinally along the strip of material to provide a plastic deformation of the ridge. The helical form of the helical strip of material is a permanent distortion due to the deformation of the ridge applied by the at least one bending head.

Abstract: System, including methods, apparatus, and kits, for bone fixation using a fixation device including a mounting portion and a fastener that attaches to the mounting portion. In some embodiments, the fixation device may include first and second mounting portions configured to be disposed across a bone from each other and secured with a fastener that extends from one of the mounting portions, through the bone, and to the other mounting portion. The system also may include a tool to facilitate installation of the fixation device.

Abstract: Haptic glove for providing haptic feedback to a user's hand, the haptic glove comprising: a base portion and one or more finger portions extending from the base portion, wherein each finger portion is pivotally movable relative to the base portion, and one or more cables, each comprising a distal end connected to a respective finger portion and a proximal end extending towards the base portion; and one or more cable control assemblies, at least one cable control assembly comprising: a constrain mechanism configured, when engaged, to constrain movement of the proximal end of a respective cable relative to the base portion, thereby constraining movement of a respective finger portion relative to the base portion, and an SMA wire arranged, on contraction, to engage or disengage the constrain mechanism.

Abstract: A computer-assisted system includes a manipulator assembly configured to couple to a cannula at a distal portion of the manipulator assembly. The cannula has a lumen configured to receive a shaft of an instrument. A cannula axis is aligned with the cannula when the cannula is coupled to the manipulator assembly. An instrument axis is aligned with the instrument when the instrument is coupled to the manipulator assembly. A controller coupled to the manipulator assembly is configured to receive an indication to reposition a remote center of motion (RCM) for the manipulator assembly while the RCM is positioned at a first location relative to the distal portion along an axis, wherein the axis is aligned with the cannula axis or the instrument axis; and in response to receiving the indication, cause the RCM to be positioned at a second location relative to the distal portion along the axis.

Abstract: An example device for repairing a tissue is described herein. The device can include a flexible carrier layer, and a support member including a plurality of micro-protrusions extending therefrom. The support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the tissue, and the micro-protrusions can be configured to mechanically interface with the tissue.

Abstract: A monitoring device configured to be attached to a body of a subject includes a physiological sensor configured to detect and/or measure physiological information from the subject, an activity sensor configured to sense physical activity information from the subject, an actuator configured to adjust stability of the monitoring device relative to the body of the subject, and a processor in communication with the activity sensor and the actuator. The processor is configured to process the physical activity information to detect a change in the physical activity of the subject and to control the at least one actuator to adjust the stability of the monitoring device relative to the body of the subject in response to detecting that a change in the physical activity of the subject has occurred.

Abstract: The present invention relates to a device and system for fixation of intra-articular and extra-articular fractures and non-unions of small bones and other small bone fragments, and more particularly to a threaded nail with a robust length and a trailing end with a cutting tip and longitudinal cutting flutes and a stepped diameter with cutting flutes at the transition point, and an optional cannulation along the central longitudinal axis of the nail.

Abstract: Systems and methods are disclosed for autonomously soothing babies. An example method may include receiving a first sound input from a microphone, processing the first sound input, determining a baby status based at least in part on the first sound input, determining an output action based at least in part on the baby status; and implementing the output action at the children's apparatus.

Abstract: Devices, systems, and methods of bone stabilization. The bone stabilization system includes a mesh body. The mesh body includes a plurality of rings, with each of the rings defining a screw hole. Bridge portions extend between and interconnect the rings. The bridge portions have a reduced thickness compared to the rings. An elongate body may also extend from the mesh body. The elongate body defines at least one screw hole.