Abstract: Safe and effective exercise poses a specific set of challenges for subjects diagnosed with diabetes. These challenges include the coordination of exercise with blood glucose monitoring and insulin administration. Failure to coordinate these factors effectively can lead to various pathologies related to aberrant blood glucose levels. Presented herein are methods, systems, algorithms, computer program products, web portals, real-time live instruction, and computer-executable code for exercise guidance and instruction specific to diabetes relief and management. The systems as disclosed herein can help ameliorate, slow, or reduce a likelihood of developing a diabetic condition.

Abstract: A subsidence monitoring system that employs an automated total monitoring stations (AMTS) in combination with a field-array of flush-mount prisms well-suited for monitoring settlement of roadways and other surfaces or structures. A method of installation of said field-array of flush-mount prism assemblies is also disclosed, along with tool for said installation.

Abstract: The present invention comprises a polymer and/or polymer composite based sleeve to be fitted between an extended body, such the neck, trunnion, and/or stem of a hip implant, and a receiving body, such as a femoral head in a hip implant, that reduces wear, decreases toxic material from wear debris, enhances the mechanical connection of the extension and receiving body, reduces or eliminates impingement with receiving body, delocalize stress concentrations, and may also serve as a modifying junction between an extension and receiving body of unmatched size. The polymeric based sleeve presently disclosed comprises an inert and/or biologically favorable material which may be used in its virgin form or contain biocompatible additives. In order to best match patient and implant requirements, modifications may be made in the length, thickness, composition, as well as the presence of a taper, or lack thereof, in order to be compatible with existing devices.

Abstract: An apparatus includes a reference array, a bone anchor, a receiver assembly coupled to the bone anchor, and an adapter axially locked with the receiver assembly. The adapter includes a proximal end coupled to the reference array and a distal end coupled to the receiver assembly.

Abstract: A swivel fitting assembly includes a female body providing a first connection end portion, and a male fitting body providing a second connection end portion. The male body and the female body are operatively coupled together to form a fluid passage between the first and second connection end portions, and are configured to permit relative rotation of the bodies relative to each other. A swivel lock mechanism is provided to rotationally lock or release the male body relative to the female body in response to a fluid pressure level in the fitting. The swivel lock includes a collar that transitions to a lock state and holds the male body when fluid pressure is at or above a predefined level. The collar transitions to a release state to enable relative rotation of the bodies when the pressure is below the predefined level.

Abstract: A UE can enable a VoWIFI service, receive hidden SSID information, and register with a core network via a RAN. The UE can monitor a first signal strength of a first signal from the RAN. The UE can scan for a second signal from a WLAN, and when found, can measure a second signal strength of the second signal. The UE can determine whether the first signal strength is at or below a first threshold. If so, and if the WLAN is untrusted, the UE can probe it with the hidden SSID information. If the untrusted WLAN responds, the UE can send an access request to an untrusted WLAN access point. The UE can receive, via the untrusted WLAN access point, an authentication challenge from an ePDG. If the UE passes the authentication challenge, the UE can register with the core network via the untrusted WLAN and the ePDG.

Abstract: A test system comprising a reactor having a fluid circuit and a test zone for an item under test. A plurality of control zones are included in the fluid circuit for controlling parameters of the fluid in accordance with control information. A control system receives input data specifying test values for the fluid parameters, predicts the behaviour of the fluid using the input data and a mathematical model of the reactor, calculates control information based on the predicted fluid behaviour, and communicates the control information to the control zones. The system can simulate transient test conditions by selective use of fluid evacuation and dilution, and by use of temperature and flow bypass circuits.

Abstract: The present disclosure provides crystalline forms of 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile, pharmaceutical compositions comprising the crystalline forms, methods of using the crystalline forms, and processes for making the crystalline forms.

Abstract: The present invention relates inter alia to expression vector production as well as application to the production of host cells for protein repertoire expression and high-throughput screening. The invention also relates to primers useful for PCR amplification of nucleotide sequences encoding human antibody variable domains.

Abstract: The present disclosure provides crystalline forms of 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile, pharmaceutical compositions comprising the crystalline forms, methods of using the crystalline forms, and processes for making the crystalline forms.

Abstract: A promotion processing system may include a point-of-sale terminal at a store to collect purchased product identifiers from products being purchased, and a promotion generation server. The server may obtain the collected purchased product identifiers from the point-of-sale terminal, determine a store-transaction count based upon the collected purchased product identifiers, and for each purchased product identifier, map the corresponding product to an aisle location within the store. The server may determine a corresponding aisle-transaction count for the aisle location corresponding to each product based upon the mapped aisle locations, and determine shopper paths of travel within the store based upon the store- and aisle-transaction counts. The server may identify a location within the store for an aisle violator sign for a promoted product located in one of the aisle locations based upon the shopper paths of travel and the aisle-transaction counts, and generate a digital promotion for the promoted product.

Abstract: The present disclosure relates to high-throughput screening methods for identifying one or more chromatography operational parameters (e.g., binding parameters) and/or reagents for purifying EVs (e.g., exosomes) from a sample using chromatography. Also disclosed herein are methods for improving one or more aspects of EV (e.g., exosome) purification, e.g., improving EV yield, increasing EV ligand density, and/or reducing impurity recovery.

Abstract: This disclosure includes expandable spinal fusion implants, instrumentation, and methods for using the same.

Abstract: Systems and methods are disclosed for managing skin in a subterranean wellbore. In an embodiment, the method includes oscillating a drawdown pressure of the subterranean wellbore in a predetermined pattern that comprises a plurality of alternating drawdown pressure increases and drawdown pressure decreases. The drawdown pressure increases of the predetermined pattern comprise increasing the drawdown pressure at a first rate, and the drawdown pressure decreases of the predetermined pattern comprise decreasing the drawdown pressure at a second rate that is different from the first rate.

Abstract: A method of detecting conditions indicative of energy meter tampering, meter faults or energy loss (e.g. due to energy theft) is disclosed. The method includes receiving energy consumption data from an energy meter indicating consumption of energy at a location served by the energy meter. Event data is also received from the meter comprising one or more events generated by the energy meter. The consumption data is analysed to detect a predetermined consumption condition. The event data is analysed to detect a predetermined event or event pattern in the event data. An alert condition is generated in response to detecting both the consumption condition and the event or event pattern.

Abstract: The present invention relates inter alia to expression vector production as well as application to the production of host cells for protein repertoire expression and high-throughput screening. The invention also relates to primers useful for PCR amplification of nucleotide sequences encoding human antibody variable domains.

Abstract: The invention is related to the preparation of protected piperidine carboxylates suitable for use as intermediates that lead, via a series of additional process steps, including a sulfation of a hydroxy urea compound, to the preparation of the beta lactamase inhibitor (2S,5R)-7-oxo-N-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide.

Abstract: An encoder may be configured to receive a first input from a user. The encoder may include a first user input area. A configurator may be configured to communicate with the encoder and the encoder may be configured to communicate with a CPU. The encoder may receive the first input from the user at the first user input area based on an encoder configuration defined by the configurator. The encoder may communicate the first input to the CPU based on the encoder configuration defined by the configurator. A panel may be configured to receive a first input from a user. The panel may include a plurality of input areas. A portable computing device may comprise a configurator. The portable computing device may be configured to communicate with a CPU.

Abstract: An encoder may be configured to receive a first input from a user. The encoder may include a first user input area. A configurator may be configured to communicate with the encoder and the encoder may be configured to communicate with a CPU. The encoder may receive the first input from the user at the first user input area based on an encoder configuration defined by the configurator. The encoder may communicate the first input to the CPU based on the encoder configuration defined by the configurator. A panel may be configured to receive a first input from a user. The panel may include a plurality of input areas. A portable computing device may comprise a configurator. The portable computing device may be configured to communicate with a CPU.

Abstract: A smoking pipe for smoking a tobacco product has an elongated pipe body with a passage therethrough a mouthpiece portion at the first end of the pipe body and a chamber formed in the second end of the pipe body opposite to the mouthpiece portion. A cartridge removably supported within the chamber receives the tobacco product therein. The cartridge can be slidably removed to allow the chamber to be cleaned and refilled simply by removing the cartridge and replacing the cartridge with a new, clean cartridge having fresh smoking product optionally already packed therein. The pipe body may be optionally formed in two body sections joined to one another by respective magnetic couplers at the abutted inner ends of the two body sections.