Abstract: The present invention relates to a pharmaceutical combination comprising, separately or together, (1) a first agent which is an ALK inhibitor or a pharmaceutically acceptable salt thereof and (2) a second agent which is a CDK inhibitor or a pharmaceutically acceptable salt thereof. The invention further relates the use of such combination in the treatment or prevention of proliferative diseases.

Abstract: A point-to-multipoint messaging processing system and method having a message processing system communicatively coupled to a message origination system for receiving message requests from a plurality of message originating agents, each message request including a message agent identification identifying the message originating, a geographically defined transmission target area for the message, a message type identifier uniquely identifying a message type, and a message, the message processing system verifying each received message request to provide a verified message, the verifying being a function of the message originating agent identification, and the message type identifier and then for each verified message request determining a point-to-multipoint message transmission system serving at least a portion of the transmission target area of the message request for message type of the message type identifier, and transmitting the message, and the message type identifier, and the transmission target area to t

Abstract: The present invention relates to systems, methods, and devices for correlating and sharing information. In particular, the invention relates to systems, methods, and devices for identifying subjects of interest suspected of involvement in one or more crimes, and sharing and correlating information relating to subjects and events. In further aspects of the invention, methods and system are provided for sharing alerts between users of electronic devices.

Abstract: A geotargeted broadcast message system and method providing processing a plurality of broadcast message requests from a plurality of broadcast message origination systems, with each broadcast message request including a broadcast message and a geographically defined broadcast target area, including a broadcast message management system communicatively to the broadcast message origination systems, receiving broadcast message requests, storing a broadcast message jurisdiction authority for each broadcast message originating agent, verifying each broadcast message request to provide a verified broadcast message, with the verifying being a function of an authority of the broadcast message originating agent to send the broadcast message to the broadcast target area, and determining one or more of point-to-multipoint broadcast message transmission systems serving at least a portion of the broadcast target area for the broadcast message request, and transmitting the broadcast message and the broadcast target area to

Abstract: A method of manufacturing a wafer. The method includes providing a wafer and testing the wafer. Based on a test result, a substance is selectively provided on the wafer to obtain an altered wafer that has at least one selected portion altered. The method includes forming a structural layer over the altered wafer.

Abstract: Representative implementations of devices and techniques provide a termination arrangement for a transistor structure. The periphery of a transistor structure may include a recessed area having features arranged to improve performance of the transistor at or near breakdown.

Abstract: The invention relates to a process and apparatus that treats waste water, in particular waste water containing surfactants and including grey water, for local reuse. According to the invention, the process comprises a) collecting waste water in a reservoir; b) injecting gas into waste water from the reservoir to form bubbles in the waste water; c) separating the bubbles, and any entrained contaminants, from the waste water; d) drying the separated bubbles and returning any water recovered from the dried bubbles to the waste water undergoing treatment; e) optionally repeating steps b) to d) to achieve the desired purification of the waste water; and f) collecting the purified waste water. The invention provides a robust process and a mechanically simple apparatus that does not require regular replacement of chemicals or filters, yet is capable of treating waste water locally, and in particular grey water for household reuse.

Abstract: Novel forms of [R-(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptatonic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease.

Abstract: The invention relates to a method of identifying VDJ recombination products which comprises the use of sequence specific enrichment and specific restriction endonuclease enzymes or other DNA-shearing approaches to provide high resolution and high throughput interrogation of antigen receptor repertoires.

Abstract: Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-?,?-Dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1-H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Forms XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX characterized by their X-ray powder diffraction, solid state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease.

Abstract: A method of manufacturing a wafer. The method includes providing a wafer that includes a plurality of semiconductor device structures, and testing at least one of the plurality of semiconductor device structures. Based on a test result, a substance is provided on a selected portion of the wafer to selectively configure a circuit element within the at least one of the plurality of semiconductor device structures.

Abstract: A method of manufacturing a wafer. The method includes providing a wafer that includes a plurality of semiconductor device structures, and testing at least one of the plurality of semiconductor device structures. Based on a test result, a substance is provided on a selected portion of the wafer to selectively configure a circuit element within the at least one of the plurality of semiconductor device structures.

Abstract: An apparatus (12) for treating water, in particular for removing surfactants from waste water, includes a vessel (14), defining an inlet (16) for receiving waste water containing air bubbles, and an outlet (20) for the exit of water, following treatment. Inside the vessel there is at least one tubular member (50) having a lower open end (52) into which the flow of waste water from the inlet may be directed in use. The tubular member (50) extends from the inlet towards a top of the vessel where an upper exit (54) from the tubular member is defined. In use, most un-aerated water entering the vessel through the inlet can exit the tubular member at the lower open end. Foam formed in the water by the air bubbles may travel up the tubular member to the upper exit, which is preferably located above the water level (60) in the vessel.

Abstract: An electronic device, such as a mobile communication device, and a method are provided for multiple-stage interface control of the device. The device is provided with a homescreen display, which includes a plurality of panels. The panels include at least one panel that is a fullscreen view of a first application executing on the device. This first application can be a messaging application, and the fullscreen view can be a unified inbox view for a plurality of different message types. The panels also include at least one launch panel having a number of graphical user interface elements, such as icons, representing access points to a corresponding application on the device.

Abstract: A method of manufacturing a wafer. The method includes providing a wafer that includes a plurality of semiconductor device structures, and testing at least one of the plurality of semiconductor device structures. Based on a test result, a substance is provided on a selected portion of the wafer to selectively configure a circuit element within the at least one of the plurality of semiconductor device structures.

Abstract: A method of manufacturing a wafer. The method includes providing a wafer and testing the wafer. Based on a test result, a substance is selectively provided on the wafer to obtain an altered wafer that has at least one selected portion altered. The method includes forming a structural layer over the altered wafer.

Abstract: A method of manufacturing a wafer. The method includes providing a wafer that includes a plurality of semiconductor device structures, and testing at least one of the plurality of semiconductor device structures. Based on a test result, a liquid is provided on a selected portion of the wafer to selectively alter at least one circuit element within the at least one of the plurality of semiconductor device structures.

Abstract: A system and method for distributing promotions to mobile devices located in a broadcast target area and as a function of a promotion client identifier, the system and method including transmitting a first plurality of promotions associated with a plurality of promotion clients having locations in a target area, receiving a promotion client identifier, receiving the transmitted promotions, and displaying one of the received promotions on a mobile device as a function of the promotion identifier.

Abstract: A method for use in manufacturing a plurality of electronic devices from a workpiece. The method includes compiling a set of data records in a data file, wherein each data record represents information uniquely associated with a respective electronic device to be manufactured from the workpiece. Based on the data file, deposition of a substance is controlled at selected locations on the workpiece.

Abstract: A method includes displaying information associated with a first application on a touch-sensitive display of an electronic device. A gesture is detected on the touch-sensitive display, which gesture indicates a request to display information associated with a second application. At least part of the information associated with the second application is displayed without opening the second application.