Patents by Inventor Anthony Robinson

Anthony Robinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9538752
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as Pseudomonas aeruginosa. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials, or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: January 10, 2017
    Assignees: POLYPHOR LTD., UNIVERSITAET ZUERICH
    Inventors: Steven J. Demarco, Wim Vrijbloed, Ricardo Dias, John Anthony Robinson, Nityakalyani Srinivas, Frank Gombert, Daniel Obrecht
  • Patent number: 9521846
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as Pseudomonas aeruginosa. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials, or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: December 20, 2016
    Assignees: POLYPHOR LTD., UNIVERSITAET ZUERICH
    Inventors: Steven J. Demarco, Wim Vrijbloed, Ricardo Dias, John Anthony Robinson, Nityakalyani Srinivas, Frank Gombert, Daniel Obrecht
  • Patent number: 9518092
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula (I) wherein Z is a template-fixed chain of 12, 14 or 18 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid), are Gly, NMeGly, Pro or Pip, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have CXCR4 antagonizing properties These ?-hairpin peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: December 13, 2016
    Assignees: POLYPHOR LTD., UNIVERSITAT ZURICH
    Inventors: Jürg Zumbrunn, Steven J. Demarco, Sergio Lociuro, Jan Wim Vrijbloed, Frank Gombert, Reshmi Mukherjee, Kerstin Moehle, Daniel Obrecht, John Anthony Robinson, Heiko Henze, Barbara Romagnoli, Christian Ludin
  • Publication number: 20160324947
    Abstract: The invention relates to lipopeptides consisting of a peptide chain comprising a parallel coiled-coil domain, a proline-rich peptide antigen, and a lipid moiety, all covalently linked, which aggregate to synthetic virus-like particles. Proline-rich peptide antigens considered contain negatively and positively charged amino acid, and at least 15% of the amino acids are proline. Such synthetic virus-like particles carrying proline-rich antigens derived from pneumococcal proteins are useful as vaccines against infectious diseases caused by Gram-positive bacteria such as Streptococcus pneumoniae.
    Type: Application
    Filed: December 2, 2014
    Publication date: November 10, 2016
    Applicant: UNIVERSITÄT ZÜRICH
    Inventors: Arin Ghasparian, Armando Zuniga, Nina Geib, Marco Tamborini, Maja Jud, Gerd Pluschke, Aniebrys Marrero Nodarse, John Anthony Robinson
  • Publication number: 20160314508
    Abstract: Disclosed is a method, system, and computer-readable medium for enabling a cross-platform, multi-component customer centric system for parking is provided. The method includes identifying a plurality of payment options which allow a customer to balance convenience, expense and self-service to enable a customer centric parking experience. The method also a plurality of means by which a customer can engage or book parking combining corporate information, loyalty information, customer affiliation information and proprietary revenue management techniques which enable a highly customer centric set of choices on how, when and where to book parking.
    Type: Application
    Filed: April 22, 2016
    Publication date: October 27, 2016
    Inventors: MICHAEL DAVID DEADERICK, ANTHONY L PAALZ, JR., WILLIAM DUTCH MILLARD, MICHAEL ANTHONY ROBINSON
  • Patent number: 9328931
    Abstract: A heating and/or cooling system for maintaining an environment at a desired temperature. The heating and/or cooling system includes a heat pump, a temperature sensor disposed to measure a temperature of the environment, and a system controller. The system controller may be configured to control a condensing temperature within the condenser such that the condensing temperature is set as low as possible while maintaining the condensing temperature a predetermined amount above the desired temperature that is being maintained. The system controller may also be configured to control the evaporating valve in order to vary, based on the measured temperature, an evaporating temperature in order to reduce the difference between the evaporating and condensing temperatures.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: May 3, 2016
    Assignee: ESG POOL VENTILATION LTD
    Inventor: Anthony Robinson
  • Publication number: 20150087577
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula (I) wherein Z is a template-fixed chain of 12, 14 or 18 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid), are Gly, NMeGly, Pro or Pip, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have CXCR4 antagonizing properties These ?-hairpin peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
    Type: Application
    Filed: September 24, 2014
    Publication date: March 26, 2015
    Applicants: Universität Zürich, POLYPHOR LTD.
    Inventors: Jürg Zumbrunn, Steven J. Demarco, Sergio Lociuro, Jan Wim Vrijbloed, Frank Gombert, Reshmi Mukherjee, Kerstin Moehle, Daniel Obrecht, John Anthony Robinson, Heiko Henze, Barbara Romagnoli, Christian Ludin
  • Publication number: 20150080317
    Abstract: The template-fixed B-hairpin peptidomimetics Cyclo(-Tyr-His-X-Cys-Ser-Ala-DPro-Dab-Arg-Tyr-Cys-Tyr-Gln-Lys-D-Pro-Pro), disulfide bond between Cys4 and Gys11, and pharmaceutically acceptable salts thereof, with X being Ala or Tyr, have CXCR4 antagonizing properties and can be used for where cancer is mediated or resulting from CXCR4 receptor activity
    Type: Application
    Filed: November 28, 2014
    Publication date: March 19, 2015
    Applicants: Universitaet Zuerich, POLYPHOR LTD.
    Inventors: Daniel OBRECHT, Frank Gombert, Steven J. Demarco, Christian Ludin, Jan Wim Vrijbloed, Kerstin Moehle, John-Anthony Robinson, Reshmi Mukherjee, Heiko Henze, Barbara Romagnoli
  • Patent number: 8921325
    Abstract: The template-fixed ?-hairpin peptidomimetics Cyclo(-Tyr-His-X-Cys-Ser-Ala-DPro-Dab-Arg-Tyr-Cys-Tyr-Gln-Lys-DPro-Pro), disulfide bond between Cys4 and Gys11, and pharmaceutically acceptable salts thereof, with X being Ala or Tyr, have CXCR4 antagonizing properties and can be used for preventing HIV infections in healthy individuals or for slowing and halting viral progression in infected patients; or where Cancer is mediated or resulting from CXCR4 receptor activity; or where immunological diseases are mediated or resulting from CXCR4 receptor activity; or for treating immuno suppression; or, in particular, for stem cell mobilization of peripheral blood stem cells and/or mesenchymal stem cell (MSC) and/or other stem cells which retention depend on the CXCR4-receptor. These ?-hairpin peptidomimetics can be manufactured by a process which is based on a mixed solid- and Solution phase synthetic strategy, using methods which are well known to those adequately skilled in peptide chemistry.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: December 30, 2014
    Assignees: Polyphor Ltd., Universität Zürich
    Inventors: Daniel Obrecht, Frank Gombert, Steven J. Demarco, Christian Ludin, Jan Wim Vrijbloed, Kerstin Moehle, John-Anthony Robinson, Reshmi Mukherjee, Heiko Henze, Barbara Romagnoli
  • Patent number: 8895499
    Abstract: ?-Hairpin peptidomimetics of the general formula Cyclo(-Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11-Xaa12-Xaa13-Xaa14-), enantiomers and pharmaceutically acceptable salts thereof, with Xaa1-Xaa14 being amino acid residues of certain types which are defined in the description and the claims, have anti-infective activity, e.g. to selectively inhibit the growth of or to kill microorganisms such as Bacillus subtilis and/or Shigella boydii. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: November 25, 2014
    Assignees: Polyphor AG, Universitat Zurich
    Inventors: Daniel Obrecht, Frank Otto Gombert, John Anthony Robinson, Krystyna Patora-Komisarska
  • Patent number: 8895695
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula (I) wherein Z is a template-fixed chain of 12, 14 or 18 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid), are Gly, NMeGly, Pro or Pip, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have CXCR4 antagonizing properties. These ?-hairpin peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: November 25, 2014
    Assignees: Polyphor Ltd., Universität Zürich
    Inventors: Jürg Zumbrunn, Steven J. Demarco, Sergio Lociuro, Jan Wim Vrijbloed, Frank Gombert, Reshmi Mukherjee, Kerstin Moehle, Daniel Obrecht, John Anthony Robinson, Heiko Henze, Barbara Romagnoli, Christian Ludin
  • Publication number: 20140187471
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as Pseudomonas aeruginosa. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials, or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
    Type: Application
    Filed: February 7, 2014
    Publication date: July 3, 2014
    Applicants: UNIVERSITAET ZUERICH, POLYPHOR LTD.
    Inventors: Steven J. DEMARCO, Wim Vrijbloed, Ricardo Dias, John Anthony Robinson, Nityakalyani Srinivas, Frank Gombert, Daniel Obrecht
  • Publication number: 20140187472
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as Pseudomonas aeruginosa. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials, or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
    Type: Application
    Filed: February 7, 2014
    Publication date: July 3, 2014
    Applicants: Universitaet Zuerich, Polyphor Ltd.
    Inventors: Steven J. DEMARCO, Wim Vrijbloed, Ricardo Dias, John Anthony Robinson, Nityakalyani Srinivas, Frank Gombert, Daniel Obrecht
  • Patent number: 8685922
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula (I) wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining Symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as Pseudomonas aeruginosa. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials, or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and Solution phase synthetic strategy.
    Type: Grant
    Filed: January 15, 2007
    Date of Patent: April 1, 2014
    Assignees: POLYPHOR Ltd., Universitaet Zuerich
    Inventors: Steven J. Demarco, Wim Vrijbloed, Ricardo Dias, John Anthony Robinson, Nityakalyani Srinivas, Frank Gombert, Daniel Obrecht
  • Publication number: 20140087994
    Abstract: Template-fixed ?-hairpin peptidomimetics of the general formula wherein Z is a template-fixed chain of 12 ?-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as Pseudomonas aeruginosa. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials, or as medicaments to treat or prevent infections. These ?-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
    Type: Application
    Filed: November 7, 2013
    Publication date: March 27, 2014
    Applicants: Universitaet Zuerich, POLYPHOR LTD.
    Inventors: Steven J. DEMARCO, Wim Vrijbloed, Ricardo Dias, John Anthony Robinson, Nityakalyani Srinivas, Frank Gombert, Daniel Obrecht
  • Publication number: 20140034285
    Abstract: A method of heating and/or cooling an area to a desired temperature comprising using a heat pump having an evaporator, a compressor, a condenser and an expansion control means each connected by a refrigerant pipe work system and the method comprising monitoring the temperature of an environment in which the evaporator is operating and using a system controller to vary in response to the monitored temperature, the temperature at which gas condenses to a fluid within the condenser to keep it as low as possible whilst maintaining the condensing temperature a predetermined amount above the desired temperature and/or also varying in response to the monitored temperature, the temperature at which a liquid expands to a gas within the evaporator in order to reduce the difference between the evaporating and condensing temperatures.
    Type: Application
    Filed: February 9, 2012
    Publication date: February 6, 2014
    Applicant: ESG Pool Ventilation LTD
    Inventor: Anthony Robinson
  • Publication number: 20130189363
    Abstract: ?-Hairpin peptidomimetics of the general formula Cyclo (-Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11-Xaa12-Xaa13-Xaa14-), enantiomers and pharmaceutically acceptable salts thereof, with Xaa1-Xaa14 being amino acid residues of certain types which are defined in the description and the claims, have anti-infective activity, e.g. to selectively inhibit the growth of or to kill microorganisms such as Bacillus subtilis and/or Shigella boydii. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
    Type: Application
    Filed: August 5, 2010
    Publication date: July 25, 2013
    Applicants: UNIVERSITÄT ZÜRICH, POLYPHOR AG
    Inventors: Daniel Obrecht, Frank Otto Gombert, John Anthony Robinson, Krystyna Patora-Komisarska
  • Publication number: 20130150299
    Abstract: The template-fixed ?-hairpin peptidomimetics Cyclo(-Tyr-His-X-Cys-Ser-Ala-DPro-Dab-Arg-Tyr-Cys-Tyr-Gln-Lys-DPro-Pro), disulfide bond between Cys4 and Gys11, and pharmaceutically acceptable salts thereof, with X being Ala or Tyr, have CXCR4 antagonizing properties and can be used for preventing HIV infections in healthy individuals or for slowing and halting viral progression in infected patients; or where Cancer is mediated or resulting from CXCR4 receptor activity; or where immunological diseases are mediated or resulting from CXCR4 receptor activity; or for treating immuno suppression; or, in particular, for stem cell mobilisation of peripheral blood stem cells and/or mesenchymal stem cell (MSC) and/or other stem cells which retention depend on the CXCR4-receptor. These ?-hairpin peptidomimetics can be manufactured by a process which is based on a mixed solid- and Solution phase synthetic strategy, using methods which are well known to those adequately skilled in peptide chemistry.
    Type: Application
    Filed: February 11, 2013
    Publication date: June 13, 2013
    Inventors: Daniel OBRECHT, Frank Gombert, Steven J. Demarco, Christian Ludin, Jan Wim Vrijbloed, Kerstin Moehle, John-Anthony Robinson, Reshmi Mukherjee, Heiko Henze, Barbara Romagnoli
  • Patent number: D764072
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: August 16, 2016
    Assignee: PARK 'N FLY SERVICE LLC
    Inventors: Michael David Deaderick, Anthony L Paalz, Jr., William Dutch Millard, Michael Anthony Robinson
  • Patent number: D772084
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: November 22, 2016
    Assignee: PARK 'N FLY SERVICE LLC
    Inventors: Michael David Deaderick, Anthony L Paalz, Jr., William Dutch Millard, Michael Anthony Robinson