Abstract: Described herein DNA-based assays that include nanostructures providing a simple, highly sensitive method for small molecule, biologic and peptide measurements that are optimized for use in a commercial, point-of-care diagnostic settings and systems. These DNA-based assays may include a combination of multiple redox molecules (e.g., methylene blue) such as between 3-8 redox molecules, and a spacer of between about 2 A and 20 A (and in particular between 3 A and 8 A), that results in an assay that has significantly greater signal and greater sensitivity as compared to prior DNA-based assays.

Abstract: Embodiments provide systems, methods, and computer storage media for a Nonsymmetric Determinantal Point Process (NDPPs) for compatible set recommendations in a setting where data representing entities (e.g., items) arrives in a stream. A stream representing compatible sets of entities is received and used to update a latent representation of the entities and a compatibility distribution indicating likelihood of compatibility of subsets of the entities. The probability distribution is accessed in a single sequential pass to predict a compatible complete set of entities that completes an incomplete set of entities. The predicted complete compatible set is provided a recommendation for entities that complete the incomplete set of entities.

Abstract: A hydrogen injection scheme can be employed via use of one or more injectors for injecting hydrogen to help entrain local mass while also generating local turbulence that can enhance mixing with a mixture of air and fuel to facilitate enhanced lean combustion, lower peak flame temperatures of combustion, and reduce nitrous oxide (NOx) emissions from the combustion of fuel. In some embodiments, the hydrogen can be injected to help transport heat released during combustion away from the injector to help avoid injector overheating as well. Different injectors can be utilized to provide a desired hydrogen injection scheme for a particular set of design and operational criteria for a gas turbine system or at least one combustion system that can be utilized in a gas turbine system.

Abstract: Systems and techniques are disclosed to establish programming of an implantable electrical neurostimulation device for treating pain of a human subject, through the use and adjustment of analgesic stimulation parameters based on trust dynamics and trust measurements. In an example, the system to establish programming of the neurostimulation device performs operations that: determine a trust measurement value that is derived from results of at least one commitment made with a human subject, via observable interactions; determine a modification of at least one neurostimulation programming parameter, based on the trust measurement value; and to cause the implantable neurostimulation device to implement the modification of the at least one neurostimulation programming parameter. Further examples are provided to produce and track the trust measurement value, as well as identify a pain susceptibility value and determine a receptiveness to analgesic effects based on these and other trust dynamics.

Abstract: A delayed messaging application that allows a user to leave future messages for one or more recipients. The application maintains regular contact with the user and release of the messages is initiated upon a failure to confirm the continued existence of the user. A user first writes one or more messages they would like delivered to one or more recipients at some point in the future, based on a triggering event. For each message, a ping controller configurable in a secure message mode wherein the message is inaccessible and the ping controller periodically pings an electronic device according to the settings and receives responses to pings. Responsive to a lack of one or more responses to one or more pings the ping controller is configured to enter an unsecured message mode wherein the message is accessible.

Abstract: There is provided a method comprising: determining an occupancy status of a first region of a vehicle; determining, based at least in part on the occupancy status, a first climate control setting for the first region; controlling a climate control system of the vehicle to adjust a climate of the first region according to the first climate control setting; determining that a second region of the vehicle is unoccupied, wherein the second region is fluidly connected to the first region; determining a second climate control setting, wherein the second climate control setting is based at least in part on the occupancy status of the first region and characteristic data associated with a predicted potential change in occupancy status for the second region; and controlling the climate control system to adjust a climate of the second region according to the second climate control setting.

Abstract: A receiver for a serial data link, including an analog front end (AFE) including a continuous-time linear equalizer (CTLE) configured to receive an input signal from a transmitter, the CTLE including a first output node; a second output node; a plurality of programmable tail current sources configured to adjust a direct current (DC) offset between the first output node and the second output node; and a calibration circuit including: a slicer configured to output a difference between a first average output voltage corresponding to the first output node and a second average output, voltage corresponding to the second output node; and a calibration counter configured to increment or decrement an offset count based on the difference, wherein the plurality of programmable tail current sources are adjusted based on a value of the offset count.

Abstract: Embodiments of the present disclosure generally relate to methods for cleaning a chamber comprising introducing a gas to a processing volume of the chamber, providing a first radiofrequency (RF) power having a first frequency of about 40 MHz or greater to a lid of the chamber, providing a second RF power having a second frequency to an electrode disposed in a substrate support within the processing volume, and removing at least a portion of a film disposed on a surface of a chamber component of the chamber. The second frequency is about 10 MHz to about 20 MHz.

Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.

Abstract: A system for integration and interoperability between disparate distributed server technologies is provided. In particular, the system may provide communications functionality between heterogenous distributed register technology networks. In this regard, the system may establish an interoperability layer between the disparate networks to allow cross-network process flows to be executed. The interoperability layer may comprise one or more network services nodes for each distributed register technology to be integrated by the system. Each network services nodes may act as an event handler for internal processes executed within a given distributed register network and be configured to send and receive data from other network services nodes regarding the execution of such processes. The respective network services may then use the data obtained regarding such internal processes to in turn execute its own processes.

Abstract: A computing system receives a request to generate one or more narrative frameworks for a worksheet. The worksheet is hosted by a third party server. The computing system interfaces with the third party server to retrieve data associated with the worksheet. The computing system infers attributes of the worksheet from the retrieved data. The attributes correspond to a type of data represented in the worksheet. The computing system generates a narrative template for the one or more narrative frameworks. The computing system generates one or more data variables for the one or more narrative frameworks based on the generated narrative template. The computing system constructs the one or more narrative frameworks by selectively retrieving data from the worksheet for each data variable of the one or more data variables in the narrative framework.

Abstract: Learning and correcting errors in text input fields to an artificial intelligence (AI) system includes receiving, by the AI system from a target system, an input text. The AI system executes a text processing operation on the input text by applying at least one transformer from a library of transformers to the input text to generate transformed text. At least one proposed correction to the input text is output by the AI system based on an analysis of the transformed text. Feedback data, associated with the at least one proposed correction, is then received from a user of the target system to iteratively learn, by the AI system, which of the transformers need be applied on future input text to accurately generate future proposed corrections on the future input text.

Abstract: Methods and apparatuses, including assays, for detection and/or quantification of tacrolimus that utilize nucleic acid-based nanostructures linked to tacrolimus. In particular, described herein are biosensors having a sensing mechanism configured to react to a tacrolimus-specific binding agent, such as an aptamer or antibody that binds tacrolimus. In some variations, these methods and apparatuses may be configured to provide an electrochemical read-out in which the nucleic acid-based nanostructure is operated in conjunction with a tacrolimus-specific binding agent for sample quantification. A biosensor or a set of biosensors as described herein can be used as a standalone measurement system for tacrolimus and/or as part of a multiplexed cartridge for multiple analytes.

Abstract: The present invention relates to a system and a method for automatic fault diagnosis, troubleshooting and resolution recommendations in a data center comprising one or more resources. The method comprises at least one collector unit [102] collecting a first data from one or more resources of the data center. A mapping unit [104] identifies a failure impact on the one or more resources based on the first data collected by the at least one collector unit. The central module unit [110] creates a detailed relationship map for the one or more virtual and physical resources based on the identified failure impact. A fault processor [106] automatically diagnoses the data center on occurrence of a fault based on the relationship map, and troubleshoots at least one of the one or more resources based on the diagnosis.

Abstract: In some implementations, a first processing component of a network device may receive first traffic data obtained by a second processing component of the network device. The first processing component may store the first traffic data as residual statistics. The first processing component may obtain second traffic data associated with a copy of a traffic stream processed by the first processing component based on storing the first traffic data as the residual statistics. The first processing component may perform a switchover from the second processing component to the first processing component. The first processing component may determine current traffic data based on the residual statistics and the second traffic data. The current traffic data may be determined based on performing the switchover from the second processing component to the first processing component.

Abstract: Systems and methods are provided for analyzing messages generated by a plurality of computing devices associated with a plurality of users in a messaging system to generate training data to train a machine learning model to determine a probability that a media content item was generated inside an enclosed location or outside, receiving a media content item from a computing device, analyzing the media content item using the trained machine learning model to determine a probability that the media content item was generated inside an enclosed location or outside, determining, based on the probability generated by the trained machine learning model, that the media content item was generated inside an enclosed location, and determining an inside temperature associated with the venue based on messages generated by a plurality of computing devices in a messaging system comprising media content items and temperature information for the venue or a similar venue type.

Abstract: In various embodiments described in the present disclosure overrides to forecast data are disaggregated to a lowest hierarchy level and derived forecasts are created based at least in part on the results. In one example, values included in the forecast are organized into a set of dimensions where the dimensions are associated with a hierarchy level of a plurality of hierarchy levels.

Abstract: A method and system for processing a transaction based on biometric data and access data is disclosed. Different accounts and providers may be used to process transactions, using different message formats, based on user-configured mappings. In one example, the method includes receiving, by a message processing system, an authorization request message from an access device, the authorization request message comprising a biometric template and access data. An interaction entity record identifier, associated with an interaction entity from among a plurality of different interaction entities that process messages in different message formats, may be retrieved. The authorization request message may be converted from a first format to a second format, the second format being compatible with message processing by the interaction entity. The converted authorization request message may be transmitted to the interaction entity for determining whether to authorize the transaction.

Abstract: An apparatus is provided which comprises: a first die having a first surface and a second surface, the first die comprising: a first layer formed on the first surface of the first die, and a second layer formed on the second surface of the first die; a second die coupled to the first layer; and a plurality of structures to couple the apparatus to an external component, wherein the plurality of structures is coupled to the second layer.

Abstract: Rubber composition for tyres with low rolling resistance and good winter properties The present invention relates to a cross-linkable rubber composition, a cross-linked rubber composition obtained by cross-linking such a rubber composition, a method of preparing a tyre and a tyre. In a cross-linkable rubber composition, the cross-linkable rubber composition comprises, per hundred parts by weight of rubber (phr): ?91 to ?99 phr of natural rubber or isoprene rubber or combination thereof, a syndiotactic 1,2 polybutadiene, and ?1 to ?100 phr of a filler comprising carbon black, wherein the ratio of the syndiotactic 1,2 polybutadiene to the carbon black is in the range of 1:8 to 1:3 and in that the ratio of the syndiotactic 1,2 polybutadiene to the carbon black is in the range of ?1:8 to ?1:3.