Abstract: Embodiments of the invention are directed to a computer-implemented method. A non-limiting example of the computer-implemented method includes accessing, using a processor system, a process-step sequence that includes a plurality process-steps and a plurality of queue-times. A process-step sequence mining operation is applied to the process-step sequence, wherein the process-step sequence mining operation is operable to make a prediction of an impact of a portion of the process-step sequence on a characteristic of a product generated by the process-step sequence.

Abstract: The present description relates to methods of treating spinocerebellar ataxia type 3 (SCA3) using substituted thieno[3,2-d]pyrimidine compounds, forms, and pharmaceutical compositions thereof.

Abstract: The present description relates to methods of treating spinocerebellar ataxia type 3 (SCA3) using substituted pyrrolo[2,3-d]pyrimidine compounds, forms, and pharmaceutical compositions thereof.

Abstract: A system and method are provided herein for modeling of force vectors for serial casts to correct orthopedic deformities includes a camera configured to capture a three-dimensional image of the deformity, a computing device programmed to generate a three-dimensional model of the deformity based on the image of the deformity, determine the boundary conditions for the deformity based on the three-dimensional image of the deformity, and generate force vectors for a series of casts to correct the deformity. In exemplary embodiments, the system can print a series of casts to correct the deformity.

Abstract: The present disclosure provides compounds of Formula (I), their methods of preparation, their methods of regeneration of the compound of Formula (I), and their methods of use for binding perfluoroalkyl substances (PFAS) contaminates from sources of PFAS contaminated water.

Abstract: Embodiments are disclosed for determining scene-based editing recommendations for video content. A method of determining scene-based editing recommendations for video content includes receiving an input video comprising video content, dividing the input video into the plurality of scenes based on the video content, identifying a representative frame for each scene, determining a plurality of editing settings for each representative frame, determining editing settings for each scene based on an effectiveness score, and generating an output video using the input video and the editing settings for each scene.

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

Abstract: A mounting device has a locking housing with a locking arm that pivots between an open, unlocked position, and a closed, locked position. The locking arm extending to a latch end having a latch hole. A bottom end of the dispensing container is placed within a container receiving space of the locking housing, and the locking arm is moved to the closed, locked position to engage the annular groove of the dispensing container to lock the dispensing container within the locking housing. The device further includes a magnetic locking mechanism for locking the locking arm in the closed, locked position.

Abstract: The present disclosure describes systems, non-transitory computer-readable media, and methods for generating object-specific-preset edits to be later applied to other digital images depicting a same object type or applying a previously generated object-specific-preset edit to an object of the same object type within a target digital image. For example, in some cases, the disclosed systems generate an object-specific-preset edit by determining a region of a particular localized edit in an edited digital image, identifying an edited object corresponding to the localized edit, and storing in a digital-image-editing document an object tag for the edited object and instructions for the localized edit. In certain implementations, the disclosed systems further apply such an object-specific-preset edit to a target object in a target digital image by determining transformed-positioning parameters for a localized edit from the object-specific-preset edit to the target object.

Abstract: A method of treating and/or preventing Rift Valley fever, comprising administering an effective amount of a compound of formula (I), formula (II), formula (III), formula (IV), formula (V), formula (VI), formula (VII) or formula (VIII), or a salt thereof, to a subject need thereof; a pharmaceutical composition comprising a compound of formula (I), formula (II), formula (III), formula (IV), formula (V), formula (VI), formula (VII) or formula (VIII), or a salt thereof, and a pharmaceutically acceptable carrier; and a pharmaceutical composition comprising a compound selected from the group consisting of compound WMA-RV1, compound WMA-RV2, compound MA-RV3, compound WMA-RV4, compound WMA-RV5, compound WMA-RV6, compound WMA-RV7, or compound WMA-RV8, or a salt thereof, and a pharmaceutically acceptable carrier.

Abstract: A method of managing user experience with a virtual reality (VR) headset includes: with a server, receiving data from a number of sensors that are detecting parameters associated with a user during use of the VR headset; with the server, analyzing the data from the sensors to predict a negative effect on the user from the use of the VR headset; and with the server, taking action to minimize the negative effect on the user that is predicted.

Abstract: An artificial intelligence (AI) based method to enhance launching of an application at a user equipment (UE) is provided. The method includes monitoring launch of the application on the UE. The method includes determining an event to be executed upon the launch of the application. The method includes categorizing the event into one of a UI updating event and a non-UI updating event. Further, generating an execution flow based on the categorization, wherein the execution flow is indicative of prioritizing the UI updating event for execution before the non-UI updating event such that prioritization prevents a mismatch of the UI components during the launch. The method includes storing the execution flow and executing the stored execution flow during a subsequent launch of the application, such that launching of the at application is enhanced.

Abstract: A control circuit obtains a first set of rules that define a conveyability range for containers as a function of conveyability constraints pertaining to an intermediary distribution facility. The control circuit also accesses conveyability constraint information for the intermediary distribution facility and generates a conveyability range for that facility by evaluating the constraint information against the first set of rules. The control circuit obtains a second set of rules that define an objective function that uses the conveyability range as a constraint to determine an optimal container pack size for the given item. (By one approach these teachings will also accommodate using at least two additional constraints, such as a so-called days-of-supply (DOS) constraint and a so-called pack-and-a-half constraint.) The control circuit then generates an optimal container pack size for the given item by evaluating the objective function against the conveyability range (and other selected constraints).

Abstract: The disclosure features non-irritating pharmaceutical compositions containing CD101 in pharmaceutical acceptable salt (e.g., CD101 acetate) or neutral form. The pharmaceutical compositions can be intravenously administered to a subject to treat fungal infections (e.g., candidiasis) in the subject.

Abstract: Exhaustive driving analytical methods, systems, are apparatuses are described. The methods, systems, are apparatuses relate to utilizing partially available data associated with driver and/or driving behaviors to determine safety factors, identify times to react to events, and contextual information regarding the events. The methods, systems, and apparatuses described herein may determine, based on a systematic model, reactions and reaction times, compare the vehicle behavior (or lack thereof) to the modeled reactions and reaction times, and determine safety factors and instructions based on the comparison.

Abstract: A computer system is configured to identify a software development environment (SDE), and generate a first prebuild of the SDE. The computer system is further configured to obtain data associated with a plurality of elements that are related to a state of the SDE, and generate a first hash based on data associated with the plurality of elements. The computer system is also configured to identify a commit to the SDE and determine that the commit changed the state of SDE by obtaining data associated with the plurality of elements, generating a second hash based on the data, and determining that the second hash is different from the first hash. In response to determining that the first commit changed the state of the SDE, the computer system then generates a second prebuild of the SDE.

Abstract: Methods of reusing and/or repurposing microelectronic devices are disclosed. A method may include receiving an indication of a selected secondary application for a microelectronic device and accessing health information for the microelectronic device. The method may further include determining whether the microelectronic device is fit for the selected secondary application responsive to the health information. Associated devices and systems are also disclosed.

Abstract: Systems and methods for evaluating attributes in supply chain management is disclosed. The system may receive data from a set of data sources corresponding to a supply chain associated with at least a product, pre-process the data based on integration of the data from each of the set of data sources, generate supply chain data based on the integrated data, analyze, via an orchestration engine, the supply chain data to assess an impact of the supply chain data on the supply chain, predict, via the orchestration engine, a state associated with a purchase event of the product in the supply chain, and generate a resolution flow to be executed in the supply chain for managing the predicted state associated with the purchase event of the product.

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.