Patents by Inventor Bette T. Korber

Bette T. Korber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110150915
    Abstract: The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
    Type: Application
    Filed: December 3, 2010
    Publication date: June 23, 2011
    Applicants: Los Alamos National Security, LLC, Beth Israel Deaconess Medical Center, Duke University, The University of Alabama at Birmingham Research Foundation
    Inventors: Bette T. Korber, Simon Perkins, Tanmoy Bhattacharya, William M. Fischer, James Theiler, Norman Letvin, Barton F. Haynes, Beatrice H. Hahn, Karina Yusim, Carla Kuiken
  • Patent number: 7951377
    Abstract: The present invention relates to mosaic clade M HIV-1 Env polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: May 31, 2011
    Assignees: Los Alamos National Security, LLC, Duke University, Beth Isreal Deaconess Medical Center, The University of Albama at Birmingham Research Foundation
    Inventors: Bette T. Korber, William Fischer, Hua-Xin Liao, Barton F. Haynes, Norman Letvin, Beatrice H. Hahn
  • Publication number: 20090324631
    Abstract: The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
    Type: Application
    Filed: August 23, 2006
    Publication date: December 31, 2009
    Applicant: LOS ALAMOS NATIONAL SECURITY, LLC LOS ALAMOS NATIONAL LABORATORY, LC/IP
    Inventors: Bette T. Korber, Simon Perkins, Tanmoy Bhattacharya, William M. Fischer, James Theiler, Norman Letvin, Barton F. Haynes, Beatrice H. Hahn, Karina Yusim, Carla Kuiken
  • Publication number: 20090198042
    Abstract: The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
    Type: Application
    Filed: August 14, 2008
    Publication date: August 6, 2009
    Inventors: Bette T. KORBER, William Fischer, Hua-Xin Liao, Barton F. Haynes, Norman Letvin, Beatrice H. Hahn
  • Patent number: 7195768
    Abstract: The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: March 27, 2007
    Assignees: Duke University, The Regents of the University of California
    Inventors: Barton F. Haynes, Bette T. Korber, Robert M. De Lorimier
  • Patent number: 7172761
    Abstract: The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: February 6, 2007
    Assignees: Duke University, The Regents of The University of California
    Inventors: Barton F. Haynes, Bette T. Korber, Robert M. De Lorimier, Hua-Xin Liao
  • Patent number: 7153509
    Abstract: The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: December 26, 2006
    Assignees: Duke University, The Regents of the University of Calforinia
    Inventors: Barton F. Haynes, Bette T. Korber, Robert M. De Lorimier
  • Publication number: 20040086506
    Abstract: The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.
    Type: Application
    Filed: May 8, 2003
    Publication date: May 6, 2004
    Applicant: DUKE UNIVERSITY
    Inventors: Barton F. Haynes, Bette T. Korber, Robert M. De Lorimier, Hua-Xin Liao
  • Publication number: 20040001851
    Abstract: The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.
    Type: Application
    Filed: February 26, 2003
    Publication date: January 1, 2004
    Inventors: Barton F. Haynes, Bette T. Korber, Robert M. De Lorimier
  • Publication number: 20030219452
    Abstract: The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates. The invention also relates to a method of inducing anti-HIV antibodies using same.
    Type: Application
    Filed: November 27, 2002
    Publication date: November 27, 2003
    Inventors: Barton F. Haynes, Bette T. Korber
  • Publication number: 20030147888
    Abstract: The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against IV and to a polyvalent immunogen suitable for use in such a method.
    Type: Application
    Filed: November 7, 2002
    Publication date: August 7, 2003
    Inventors: Barton F. Haynes, Bette T. Korber, Robert M. De Lorimier