Abstract: Apparatus and techniques described herein can include using an electronic circuit comprising a rectifier circuit, an open-circuit voltage (OCV) sampling circuit coupled to the output of the rectifier circuit, and a regulator circuit coupled to the output of the rectifier circuit. In an example, an isolation switch can be located between the regulator circuit and the rectifier circuit, the isolation switch configured to isolate the regulator circuit from the rectifier circuit for sampling of the open-circuit voltage by the open-circuit voltage sampling circuit. In another example, a buffer circuit can be used, such as placed in-line with a divider circuit between a divider circuit and an open-circuit voltage sampling capacitor. In this manner, the buffer circuit can provide a low output impedance, isolating the voltage sampling capacitor from the divider circuit.

Abstract: A carotenoid oil suspension and preparation method thereof are provided. The method includes the following steps: a) mixing carotenoid with organic solvent, heating the mixture to dissolve the carotenoid sufficiently to obtain carotenoid solution; b) introducing the carotenoid solution obtained in step a) into a vegetable oil solution stirred in high speed by spraying, meanwhile recovering the organic solvent generated during spraying under vacuum condition, then, simultaneously completing recycling and spraying, thereafter, obtaining carotenoid oil suspension; wherein, the carotenoid oil suspension comprises a carotenoid crystal with an average particle size of less than 5 ?m. The method is applicable in industrial scale with continuous operation and increased efficiency without additional carotenoid crystal grinding processes, and decreases the degradation of carotenoid during the preparation process of carotenoid oil suspension.

Abstract: The invention relates to substituted pyridine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, A1, A2, E, G, Z1, and Z2 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.

Abstract: An active voltage divider circuit is provided comprising: a first node; a second node; a third node; multiple FET load devices coupled in series between the first node and the second node; multiple first switches, each associated with a different FET load device and configured to selectably couple a respective associated bypass circuit between source and drain of its associated FET load device; and second switch circuitry configured to selectably couple a drain of a FET load device, from among the multiple FET load devices, to the third node.

Abstract: The present disclosure provides pyrimidine diol amides of Formula (I), and the pharmaceutically acceptable solvates and prodrugs thereof, wherein A1, X, A2, W1, W2, W3, R1, R2, and R4 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present disclosure are especially useful for treating pain.

Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.

Abstract: This application discusses, among other things apparatus and methods for a voltage boost circuit. In an example, a voltage boost circuit can include first and second inverters, sharing a first supply node, and sharing a second supply node, a first charge transfer capacitor, configured to couple a first clock signal to the first inverter output, a second charge transfer capacitor, configured to couple a second clock signal to the second inverter output, the second clock signal being out-of-phase with the first clock signal, a first gate drive capacitor, configured to couple the first clock signal to the second inverter input, and a second gate drive capacitor, configured to couple the second clock signal to the first inverter input.

Abstract: The present disclosure provides pyrimidines of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein A1, X, A2, G, Y, n, R2a, R2b, and R3 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I and the pharmaceutically acceptable salts and solvates thereof to treat a disorder responsive to the blockade of one or more sodium channels. In one embodiment, compounds of the present disclosure are useful for treating pain.

Abstract: The present invention provides a high-content carotenoid compound from adonis amurensis. The content of the total carotenoid of the carotenoid compound is greater than 95%. The content of all-trans (3S, 3?S)-carotenoid is greater than 80%. The carotenoid crystals have a high purity, and can be used in multiple forms in the fields of a dietary supplement of a human being, a food additive, a feed additive and a cosmetic product. In addition, the present invention also provides a method for manufacturing the compound.

Abstract: An impedance matching circuit is provided for use with a piezotransducer that includes a parasitic capacitor comprising: an inductor coupled in parallel with the parasitic capacitor; a peak and valley detection circuit configured to detect output voltage waveform peaks and valleys; a first switch circuit configured to bias flip the output voltage waveform at a selectable first time relative to a detected peak and at a selectable first time relative to a detected valley; a second switch circuit configured to couple the inductor to the energy storage circuit at a selectable second time following each output voltage bias flip; an energy monitoring circuit to provide an indication of energy flow from the inductor to the energy storage circuit following each output voltage bias flip; and a maximum power point tracking (MPPT) circuit configured to select the first time and the second time based at least in part upon the indicated energy flow.

Abstract: A device to detect an electrical signal is provided. The device includes sensing, output, and pull-down nodes. The device includes a pull-down circuit having a native metal-oxide-semiconductor field-effect transistor (MOSFET) to pull down the output node to approximately a voltage of the pull-down node. The device includes a switch circuit having a junction field-effect transistor (JFET). The JFET turns on the pull-down circuit in response to a voltage of the sensing node being less than a first threshold. The JFET also turns off the pull-down circuit in response to the voltage of the sensing node being greater than the first threshold.

Abstract: The invention discloses a method for preparing high-content zeaxanthin. In the conventional preparation methods, some methods adopt certain toxic organic solvents; some methods require the multi-step crystallization process; and some methods are featured by long reaction time, high temperature and lower product yield, thus being not suitable for industrial production. The invention adopts lutein crystal or its fatty acid ester as the raw material and utilizes isomerization reaction to produce zeaxanthin, and is characterized in that a mixed catalyst consisting of an organic base catalyst and a cocatalyst is used in the isomerization reaction, wherein the cocatalyst is palladium carbon. The invention has the advantages of simple process route, low reaction temperature, short reaction time, good product purity and high yield, thus being suitable for industrial production, and no poisonous and harmful organic solvent residues in the product, thus being suitable for the use as a food additive or drug.

Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.

Abstract: An apparatus comprises a switching power circuit and a control circuit. The switching power converter circuit includes an output port for electrical coupling to a variable load, an input port for electrically coupling to a first energy source, wherein the energy density of the first energy source is insufficient to meet a peak energy requirement of the variable load, an input/output port for electrical coupling to a second energy source, and one inductor electrically coupled to the input port and a circuit node, wherein the electrical coupling is non-switchable. The control circuit is configured to charge the inductor using the first energy source via the input port, to provide energy from the inductor to the load via the output port, and to provide both of, via the input/output port, energy from the inductor to the second energy source and energy from the second energy source to the variable load.

Abstract: Embodiments are directed to processing queries using schema graph traversal and to establishing a schema graph that allows queries to be answered by traversing graph nodes. In one scenario, a computer system receives a query which specifies relational tables and corresponding relationships that are to be retrieved from a relational database. The computer system accesses a schema graph that includes graph nodes representing relational tables, as well as edges that identify relationships between the relational tables. The graph nodes include relational data that was loaded from one storage area (e.g. a non-volatile storage area), and the schema graph is stored in a second storage area (e.g. a volatile storage area). The computer system then traverses the schema graph, beginning at a set of graph nodes and continuing along the edges to other graph nodes until the query has been satisfied, and then reports the results of the graph traversal.

Abstract: An apparatus comprises an output port for a circuit load, a first input port for an energy harvest source, an input/output port a second energy source, a first circuit path from the energy harvest source to the second energy source at the input/output port and to the variable load at the output port, a second circuit path from the second energy source to the output port, a cold start circuit that produces a first voltage level at the output port by charging a capacitor at the output port using energy of the energy harvest source, and a main converter circuit that produces a second regulated voltage level at the input/output port using energy of the energy harvest source when the voltage at the output port capacitor is above a specified voltage value and uses the energy of the capacitor at the output port during startup of the main converter circuit.

Abstract: The present invention provides a method for producing and purifying ?-carotene by Blakeslea trispora fermentation and use thereof. The method comprises the following steps: a) separately inoculating the Blakeslea trispora strains onto a PDA culture medium so as to obtain a spore suspension; b) propagating spores in a seeding tank so as to obtain seeds for fermentation; c) inoculating the seeds for fermentation onto a fermenter and fermenting said seeds; d) adjusting the fermentation liquid to be basic by using an organic or inorganic base, and filtering so as to obtain wet mycelia; e) treating the wet mycelia with a hydrophobic non-polar organic solvent; f) mixing the wet mycelia with an organic solvent of ester and obtaining a concentrated solution by extracting; g) adding a saturated monohydric alcohol into the concentrated solution, and filtering and crystallizing so as to obtain pure ss-carotene. The content of the ss-carotene in the present invention exceeds 96%, and the yield is above 85%.

Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.

Abstract: The present disclosure provides substituted pyrimidine compounds of Formula (I), and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein A1, X, A2, W1, W2, W3, E, Z, and R4 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present disclosure are especially useful for treating pain.

Abstract: The present disclosure provides substituted pyrimidine carboxamides of Formula (I) and the pharmaceutically acceptable salts and solvates thereof, wherein A1, X, A2, W1, W2, W3, E, Z, and R4 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present disclosure are especially useful for treating pain.