Abstract: Enabling a relatively fast look up for a rule associated with an arbitrarily selectable IP address. In one embodiment, RSBound objects are sorted into an array where each RSBound object is composed of a bound IP address (BIP), sister BIP, type, index, sister index, and a configured rule. The BIPs are derived from arbitrary user-specified IP addresses or IP address ranges. Each single IP address configuration derives one RSBound entry, where the BIP is the given IP address itself; and each IP range configuration derives two RSBound entries, and the range's lower bound and upper bound are their respective BIPs. The array is sorted primarily based on the RSBound's BIP value, and their type and pair information are the tiebreakers. If a configured rule needs to be searched for a given IP address, a binary search is performed first to find a starting entry, from where a jump-skip search is performed to find the best matching rule for the given IP address.

Abstract: Certain known and novel pyruvate derivatives are particularly active in restoring or preserving metabolic integrity in oxidatively competent cells that have been subjected to oxygen deprivation. These pyruvate-derived compounds include, but are not limited to oximes, amides, pyruvate analogues, modified pyruvate analogues, esters of pyruvate (e.g., polyol-pyruvate esters, pyruvate thioesters, glycerol-pyruvate esters and dihydroxyacetone-pyruvate esters). Such pyruvate derivatives (including single tautomers, single stereoisomers and mixtures of tautomers and/or stereoisomers, and the pharmaceutically acceptable salts thereof) are useful in the manufacture of pharmaceutical compositions for treating a number of conditions characterized by oxidative stress.

Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.

Abstract: The present invention provides a system and method for monitoring network appliances using formatted data files. A system for monitoring a network appliance by recording operational data in formatted data files includes a data management module and a data presentation module. The data management module is configured to determine selected operational data associated with the network appliance and to record the selected operational data in formatted data files. The selected operational data are a subset of data regarding transactions performed by the network appliance. The data management module is also configured to record the selected operational data with minimum processing. The data presentation module is configured to present statistical data. The statistical data is determined from the selected operational data in the formatted data files. The data presentation module is also configured to provide the statistical data in real-time.

Abstract: Certain known and novel pyruvate derivatives are particularly active in restoring or preserving metabolic integrity in oxidatively competent cells that have been subjected to oxygen deprivation. These pyruvate-derived compounds include, but are not limited to oximes, amides, pyruvate analogues, modified pyruvate analogues, esters of pyruvate (e.g., polyol-pyruvate esters, pyruvate thioesters, glycerol-pyruvate esters and dihydroxyacetone-pyruvate esters). Such pyruvate derivatives (including single tautomers, single stereoisomers and mixtures of tautomers and/or stereoisomers, and the pharmaceutically acceptable salts thereof) are useful in the manufacture of pharmaceutical compositions for treating a number of conditions characterized by oxidative stress.

Abstract: Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.

Abstract: An ink cartridge has an ink tank for reserving ink and a joint connected to the ink tank, the joint including an outer frame having an ink channel, and a sealing member made of an elastic material and received in the outer frame, the sealing member having a cylindrical portion and a valve portion. When an ink supply pipe having an ink inlet is inserted into the cylindrical portion, the cylindrical portion abuts against an outer circumference of the ink supply pipe on an ink flow downstream side of the ink supply pipe with respect to the ink inlet. The valve portion leaves the outer frame so as to open the ink channel when the ink supply pipe is inserted into the cylindrical portion, and when the ink supply pipe is not inserted into the cylindrical portion, the valve portion abuts against the outer frame to close the ink channel.

Abstract: A system and method for regenerating optical signals comprising a clock recovery circuit coupled to a transmission line, a first optical gating device having an input port coupled to the transmission line and a clock port coupled to the clock recovery circuit, and a second optical gating device having an input port coupled to a continuous wave (CW) laser and a clock port coupled to the output of the first optical gating device, wherein the optical gating devices may be terahertz optical asymmetric demultiplexers (TOADs).

Abstract: In an application-level background transport service, a receiver node infers the available network capacity between itself and a sender node over a control interval. Based on the inferred available network capacity, the receiver node adjusts its receive window size accordingly in order to conservatively optimize the bandwidth used by a background transfer without degrading performance of other foreground transfers on the network. The adjusted receive window size is communicated to the sender node, which is likely to adjust its send window size based on the adjusted receive window size.

Abstract: 7,8-Bicyclic-chroman derivatives of Formula I: wherein the substituents are defined as in the specification or the pharmaceutically acceptable salts thereof, are disclosed. They are useful for the treatment of inflammatory disorders, neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.

Abstract: The invention relates the method of treatment or amelioration of mitochondrial disorders such as Alzheimer's disease, Parkinson's disease, Friedreich's ataxia (FRDA), cerebellar ataxias, Leber's hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Myoclonic Epilepsy with Ragged Red Fibers (MERFF), amyotrophic lateral sclerosis (ALS), motor neuron diseases, Huntington's disease, macular degeneration, and epilepsy, with chroman derivatives of Formula I or Formula II as described herein.

Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.

Abstract: A method of reducing the appearance of skin conditions associated with loss of skin tightness, skin firmness, or dark circles under the eyes with topical compositions comprising compounds of any of the Formulae I or Ia as described herein, is disclosed.

Abstract: The invention provides a two-phase hash value matching technique in message protection systems. This invention further improves the performance of message protection systems by avoiding computations associated with sophisticated signature hash value (SSHV) where possible. A message protection system that implements the two-phase hash value matching technique caches rough outline hash values (ROHVs) of previously scanned objects. The system can roughly distinguish one object from another using ROHVs. The system performs an initial check using ROHVs before performing the relatively time-consuming computations associated with SSHVs.

Abstract: A process for making an insulating glass assembly is disclosed, the process including applying a sealant composition to a surface of a spacer; contacting the sealant composition with a glass pane, and applying pressure on the glass pane to bond the glass pane to the spacer through the sealant composition, the pressure being applied at an ambient temperature of from about 15° C. to about 60° C.

Abstract: The invention provides a system and method for updating network appliances using urgent update notifications. The network appliances periodically initiates connection to “poll” updates from the update server and the update server collects IP addresses from the connections and updates an IP address log. The update server obtains updates for the network appliances and determines whether a particular update is urgent. When an urgent update is available, the server delivers an urgent update notification (UUN) to each known network appliance through an existing port used for messaging. Each network appliance receives the UUN and distinguishes it from other messages. In response to the UUN, each network appliance automatically connects to the server, obtains the urgent update and installs the urgent update.

Abstract: The present invention provides a system and method for monitoring network appliances using well-formatted data files. A system for monitoring a network appliance by recording operational data in well-formatted data files includes a data management module and a data presentation module. The data management module is configured to determine selected operational data associated with the network appliance and to record the selected operational data in well-formatted data files. The selected operational data are a subset of data regarding transactions performed by the network appliance. The data management module is also configured to record the selected operational data with minimum processing. The data presentation module is configured to present statistical data. The statistical data is determined from the selected operational data in the well-formatted data files. The data presentation module is also configured to provide the statistical data in real-time.

Abstract: A method for detecting and/or quantifying a target DNA or RNA present in a sample by a isometric primer extension method is disclosed. The method includes carrying out a primer extension reaction in the absence of a free nucleotide so that the primer extension reaction is stopped where the absent nucleotide would have been inserted. Thus, as the amount of incorporation of a labeled nucleotide on the primer extended product is detected, the amount of the target RNA or DNA in the sample is measured.

Abstract: A stepper motor control circuit reduces ripple current by applying both fast and slow current decays to a motor phase when current is being reduced in the motor phase while following a falling current waveform. The control circuit uses an initial fast decay to reduce a winding current and then switches to a slow decay until a winding current is sampled again. The control circuitry samples a winding current and compares the sampled current to a reference current to determine if current is to be applied or reduced using fast and/or slow decay methods. Different phase current sample circuits allow either constant current sensing or selective current sensing.

Abstract: A mail transfer agent adapted for determining the disposition of incoming e-mail from a sender includes a penalty count filter module which functions on the basis of current communication system resource usage, such as the number of concurrent TCP connections being maintained, and penalty counts assigned for cumulative undesirable sender activity such as sending large e-mail files. The penalty count filter module can operate in a selective-rejection state accepting e-mail from senders without a penalty count and randomly accepting other e-mail, and in a random-rejection state rejecting all e-mail from senders with a penalty count and randomly rejecting other e-mail. The rejection rates can be increased or decreased in response to a detected increase or decrease in the usage of system resources.