Patents by Inventor Brian Spencer

Brian Spencer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10947302
    Abstract: In alternative embodiments, provided are compositions such as antibodies, e.g., single chain antibodies, that target 3-repeat (3R) Tau for the treatment of neurodegenerative disorders and taupathies such as Alzheimer's Disease (AD), Pick's Disease (PiD) and Fronto-temporal lobar degeneration (FTLD), or any disorder or condition associated with a 3R Tau accumulation, and methods for making and using them. In alternative embodiments, provided are brain-penetrating antibodies that specifically recognize 3R Tau, and methods of using them to treat, ameliorate, prevent or decrease the symptoms of neurodegenerative disorders including taupathies such as Alzheimer's Disease (AD), Pick's Disease (PiD) and Fronto-temporal lobar degeneration (FTLD), or any disorder or condition associated with a 3R Tau accumulation.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: March 16, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Eliezer Masliah, Brian Spencer, Edward Rockenstein
  • Publication number: 20210024583
    Abstract: In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for transporting nucleic acids such as oligonucleotides to and across the blood brain barrier (BBB) and into the central nervous system (CNS). In alternative embodiments, provided herein are ApoB11-comprising chimeric or synthetic peptides useful for the delivery of nucleic acids such as oligonucleotides to the CNS for the treatment, prevention or amelioration of a CNS disease, infection or condition, or for diagnostic purposes.
    Type: Application
    Filed: May 13, 2020
    Publication date: January 28, 2021
    Inventors: Brian SPENCER, Robert RISSMAN
  • Publication number: 20200181245
    Abstract: In alternative embodiments, provided are compositions such as antibodies, e.g., single chain antibodies, that target 3-repeat (3R) Tau for the treatment of neurodegenerative disorders and taupathies such as Alzheimer's Disease (AD), Pick's Disease (PiD) and Fronto-temporal lobar degeneration (FTLD), or any disorder or condition associated with a 3R Tau accumulation, and methods for making and using them. In alternative embodiments, provided are brain-penetrating antibodies that specifically recognize 3R Tau, and methods of using them to treat, ameliorate, prevent or decrease the symptoms of neurodegenerative disorders including taupathies such as Alzheimer's Disease (AD), Pick's Disease (PiD) and Fronto-temporal lobar degeneration (FTLD), or any disorder or condition associated with a 3R Tau accumulation.
    Type: Application
    Filed: November 3, 2017
    Publication date: June 11, 2020
    Inventors: Eliezer MASLIAH, Brian SPENCER, Edward ROCKENSTEIN
  • Patent number: 10470225
    Abstract: The disclosure is related to searching for a second device to provide a service that a first device is attempting to establish. The first device sends a search profile and a capabilities profile to the second device using near field communication (NFC), the search profile including criteria describing the service the first device is attempting to establish, the capabilities profile including connection capabilities of the first device, receives a score from the second device, the score indicating a closeness of a match between the search profile and the capabilities profile and one or more services and capabilities of the second device, and determines whether to connect with the second device to establish the service based on the received score.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: November 5, 2019
    Assignee: QUALCOMM Incorporated
    Inventors: Haijun Zhao, Brian Spencer
  • Patent number: 10215336
    Abstract: A pressure vessel comprising a pipe closed at each end with a novel plug/compression cap, the plug at one end of the pipe having a port for connection to a pressure regulating device.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: February 26, 2019
    Assignee: SPENCER COMPOSITES CORPORATION
    Inventors: Zachary Spencer, Brian Spencer
  • Patent number: 10071529
    Abstract: This invention relates to methods of fabricating components of a pressure vessel using a dicyclopentadiene prepolymer formulation in which the purity of the dicyclopentadiene is at least 92% wherein the formulation further comprises a reactive ethylene monomer that renders the prepolymer formulation flowable at ambient temperatures and to pressure vessels that are fabricated by said methods.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: September 11, 2018
    Assignee: BLUE WAVE CO S.A.
    Inventors: Francesco Nettis, Brian Spencer, Zachary Spencer
  • Publication number: 20180135803
    Abstract: A pressure vessel comprising a pipe closed at each end with a novel plug/compression cap, the plug at one end of the pipe having a port for connection to a pressure regulating device.
    Type: Application
    Filed: October 19, 2017
    Publication date: May 17, 2018
    Inventors: Zachary Spencer, Brian Spencer
  • Patent number: 9829153
    Abstract: A pressure vessel comprising a pipe closed at each end with a novel plug/compression cap, the plug at one end of the pipe having a port for connection to a pressure regulating device.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: November 28, 2017
    Assignee: SPENCER COMPOSITES CORPORATION
    Inventors: Zachary Spencer, Brian Spencer
  • Patent number: 9606409
    Abstract: An electrochromic insert adapted to be fitted into an existing window frame allowing an existing window to be retrofit to have the benefits of electrochromics. The insert may have a scaffold that fits into a window frame. Securing the insert to the frame may occur through a variety of ways including a bracket, a flexible tab, a brace, a screw, a bolt, a projection, a detent, and an adhesive. The technology allows for the electrochromic insert to include an electrochromic device, energy collection device, an energy storage device, and an electrochromic device controller. Such a configuration may be considered autonoumous such that it need not draw power from another source.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: March 28, 2017
    Assignee: ITN Energy Systems Inc.
    Inventors: Brian Spencer Berland, Michael Wayne Stowell, Jr.
  • Publication number: 20170064073
    Abstract: In an embodiment, a mobile device is equipped with an application processor configured to execute a HLOS and a secondary processor(s) configured to control sensor(s) coupled to the mobile device. The mobile device monitors the sensor(s) while the mobile device is operating in a low power mode that is characterized by one or more cores of the application processor being in a power collapse state or dormant state. The mobile device identifies a user action based on the monitoring and communicates, while the mobile device continues to operate in the low power mode, with detected proximate device(s) over a local wireless communications interface to request that at least one device action changing a user interface output feature and/or a user environment feature be implemented at the detected proximate device(s).
    Type: Application
    Filed: July 7, 2016
    Publication date: March 2, 2017
    Inventors: Brian SPENCER, Mitchell WILLIAMS, JR.
  • Publication number: 20170064753
    Abstract: The disclosure is related to searching for a second device to provide a service that a first device is attempting to establish. The first device sends a search profile and a capabilities profile to the second device using near field communication (NFC), the search profile including criteria describing the service the first device is attempting to establish, the capabilities profile including connection capabilities of the first device, receives a score from the second device, the score indicating a closeness of a match between the search profile and the capabilities profile and one or more services and capabilities of the second device, and determines whether to connect with the second device to establish the service based on the received score.
    Type: Application
    Filed: March 26, 2014
    Publication date: March 2, 2017
    Inventors: Haijun ZHAO, Brian SPENCER
  • Patent number: 9581741
    Abstract: Systems and methods for creating an infrared-control coated thin film device with certain visible light transmittance and infrared reflectance properties are disclosed. The device may be made using various techniques including physical vapor deposition, chemical vapor deposition, thermal evaporation, pulsed laser deposition, sputter deposition, and sol-gel processes. In particular, a pulsed energy microwave plasma enhanced chemical vapor deposition process may be used. Production of the device may occur at speeds greater than 50 Angstroms/second and temperatures lower than 200° C.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: February 28, 2017
    Assignee: ITN ENERGY SYSTEMS, INC.
    Inventors: Brian Spencer Berland, Michael Wayne Stowell, Jr., Russell Hollingsworth
  • Publication number: 20170040645
    Abstract: The technology relates to depositing free-standing electrical devices on a substrate and electrically connecting two or more of the free-standing electrical devices with the aid of a bendable scoring lines. These bendable scoring lines allow the thin-film substrate to be bended, or folded, to form a specific shape. Electrical devices include electrochromic devices or solid state batteries.
    Type: Application
    Filed: October 17, 2016
    Publication date: February 9, 2017
    Inventors: Brian Spencer Berland, Michael Wayne Stowell, Jonathan Michael Banks, Calvin Roger Sprangers, Andrew Colclasure
  • Patent number: 9562555
    Abstract: A fastener assembly includes an insert having a head and a sleeve extending from a bottom surface of the head, with the insert further defining an internal cavity. The head of the insert abuts a first panel with the sleeve extending through a first preformed hole in the first panel. A second panel with a second preformed hole is aligned with the first panel, and a shaft of a fastener pin is inserted through the second preformed hole and into the internal cavity of the insert. Upon rotating the fastener pin, a tee portion at the end of the shaft engages a seat positioned in the internal cavity of the insert. The fastener assembly also includes a compression member positioned around the shaft of the fastener pin that biases the tee portion of the fastener pin into engagement with the seat of the insert.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: February 7, 2017
    Assignee: Infinite Technologies, Inc.
    Inventors: Casey Aaron Talbot, Andrew W. Gill, Robert Brian Spencer, John D. Taylor, Kevin A. Spencer
  • Patent number: 9470350
    Abstract: The invention relates to improved metal/composite interfaces, particularly for risers used in offshore oil and gas production to connect a subsea oil well to a surface drilling/production facility. The invention provides a composite hoop structure configured to a bearing surface of a metal groove of metal liner over which axial fibers are laid. The composite hoop structure provides for improved transition of axial, torsional and compressive forces between composite fibers and metal surfaces of the metal liner.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: October 18, 2016
    Assignee: Spencer Composites Corporation
    Inventors: Brian Spencer, Richard Grover
  • Patent number: 9472814
    Abstract: The technology relates to depositing free-standing electrical devices on a substrate and electrically connecting two or more of the free-standing electrical devices with the aid of a bendable scoring lines. These bendable scoring lines allow the thin-film substrate to be bended, or folded, to form a specific shape. Electrical devices include electrochromic devices or solid state batteries.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: October 18, 2016
    Assignee: ITN ENERGY SYSTEMS, INC.
    Inventors: Brian Spencer Berland, Michael Wayne Stowell, Jonathan Michael Banks, Calvin Roger Sprangers, Andrew Colclasure
  • Patent number: 9416918
    Abstract: The present invention is directed to a protected pressure vessel comprising a one-piece electrically conductive composite boss that is isolated from contact with materials that have an electrical potential that differ from that of the conductive composite boss so as to substantially eliminate the possibility of galvanic corrosion cause by the differences in electrical potential.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: August 16, 2016
    Assignee: BLUE WAVE CO S.A.
    Inventors: Francesco Nettis, Brian Spencer, Zachary Spencer
  • Patent number: 9377046
    Abstract: A fastener assembly is provided that includes a female insert having a head and a sleeve which extends from the head. The head of the female insert abuts a first panel, with the sleeve extending through a first preformed hole in the first panel. The distal end of the sleeve thus protrudes from the first preformed hole of the first panel and is then crimped around a washer to mechanically connect the female insert to the first panel. The female insert may also include one or more adhesive receptacles to further adhere the female insert to the first panel. A second panel with a second preformed hole is aligned with the first panel, and a male fastener having a base and a shank that extends from the base is inserted through the second preformed hole and into the female insert to connect the first panel and the second panel.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: June 28, 2016
    Assignee: Infinite Technologies, Inc.
    Inventors: Clint J. Lackey, Casey Aaron Talbot, Robert Brian Spencer
  • Publication number: 20160084437
    Abstract: A pressure vessel comprising a pipe closed at each end with a novel plug/compression cap, the plug at one end of the pipe having a port for connection to a pressure regulating device.
    Type: Application
    Filed: September 18, 2014
    Publication date: March 24, 2016
    Inventors: Zachary Spencer, Brian Spencer
  • Patent number: 9217198
    Abstract: The present disclosure describes methods of inserting lithium into an electrochromic device after completion. In the disclosed methods, an ideal amount of lithium can be added post-fabrication to maximize or tailor the free lithium ion density of a layer or the coloration range of a device. Embodiments are directed towards a method to insert lithium into the main device layers of an electrochromic device as a post-processing step after the device has been manufactured. In an embodiment, the methods described are designed to maximize the coloration range while compensating for blind charge loss.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: December 22, 2015
    Assignee: ITN Energy Systems, Inc.
    Inventors: Brian Spencer Berland, Bruce Roy Lanning, Jonathan Mack Frey, Kathryn Suzanne Barrett, Paul Damon DuPont, Ronald William Schaller