Abstract: Provided herein are compositions and methods for the treatment of allergy, such as food allergy. Also provided herein are compositions and methods for modulating an immune response associated with allergy and/or inducing immune tolerance or desensitization to an allergy, such as a food allergy.

Abstract: A device for use in a gas cooking grill has a central peaked structure having a front end and a back end with a longitudinal ridge of a first height spanning from the front end to the back end, and first and second pluralities of lower peaked ridges extending laterally from both first and second sides of the central peaked structure with each individual peaked ridge of the first and second plurality of lower peaked ridges being separated by a valley therebetween. Each individual peaked ridge of the first and second plurality of lower peaked ridges has a height that is lower than the first height of the longitudinal ridge.

Abstract: Provided herein are methods for decreasing dysbiosis, restoring the microbiome, and/or increasing recovery of a healthy microbiome (e.g. following a dysbiosis inducing event), by administering pharmaceutical compositions to a subject. Also provided are methods for protecting the microbiome of a subject and/or colonizing the microbiome of a subject by administering pharmaceutical compositions to the subject.

Abstract: A system has a drive mechanism affixed to an auger to selectively impart rotational forces to the auger for movement of pellet fuel for a cooking grill, and a lever arm affixed in a pivoting relationship to the drive mechanism and to a fixed location separate from the drive mechanism such that manipulation of the lever arm results in longitudinal movement of the auger.

Abstract: A lower housing has a fuel grate situated at a predetermined level within the lower housing for supporting a fuel source. The lower housing has a first wall defining a plurality of air intake openings proximate the level of the fuel grate.

Abstract: A combustion chamber has an inner wall defining an inner chamber. The inner wall is perforated to admit combustion air into the inner chamber. The combustion chamber has an outer wall defining an outer chamber. The outer wall is perforated to admit combustion air from a pressurized air plenum to the inner wall. The inner and outer wall are spaced apart such that air may flow between the inner and outer walls.

Abstract: Provided herein are methods for decreasing dysbiosis, restoring the microbiome, and/or increasing recovery of a healthy microbiome (e.g. following a dysbiosis inducing event), by administering pharmaceutical compositions to a subject. Also provided are methods for protecting the microbiome of a subject and/or colonizing the microbiome of a subject by administering pharmaceutical compositions to the subject.

Abstract: An enclosure for use in a cooking grill. The enclosure has a lower portion defining an opening that receives combustion gases from a combustion source via a bottom opening, and an upper portion interposing the lower portion and the cooking grate and having a floor with an opening that receives the lower portion and combustion gases therefrom and directs them to the cooking grate. The floor slopes to a grease drain.

Abstract: A cooking griddle having a body, a griddle plate defining at least one versatile section that can be removed, flipped over, or replaced by a secondary cooking member, and a heat source. The versatile sections include a griddle orifice and a sear griddle orifice. Secondary cooking members locate on or in the versatile sections and include a griddle dual side plate having a first side with a non-stick coating and a second side with dimples or ridges, a pizza plate, a wok, a steamer assembly, a member having a perforated surface for allowing flame to char food, a grate, and a lower profile lid. Supports may be provided below the griddle dual side plate in the form of brackets affixed to the griddle plate, a circular ring defining a shelf, and pivoting or extendable brackets. An elevation mechanism elevates a secondary cooking member for allowing air flow.

Abstract: A needle hub (10) for a pen needle is provided with an enlarged surface for contact with the skin of a patient. The enlarged surface is provided with a surface having a dimension and shape to enable a needle or cannula to penetrate the skin to a desired depth and permit substantially the entire exposed length of the needle or cannula to penetrate the skin to the desired depth. The surface of the needle hub can be formed by an inner cone shaped member (26) forming a first contact surface with a surface area of about 1-5 mm2 and an outer ring (28) at a peripheral edge forming a second contact surface with a combined surface area of about 15 to 50 mm2.

Abstract: A floor and an upright sidewall formed from two vertically coaxial components, each component having a floor baffle with a plurality of floor openings defined therein, each floor retained within a respective upright sidewall with a plurality of sidewall openings defined therein. The floor openings and the sidewall openings cooperate between the two coaxial components such that flow of gases through the floor and upright sidewall of the baffle structure is controlled by rotation of the two vertically coaxial components relative to one another.

Abstract: A combustion chamber has an inner wall defining an inner chamber. The inner wall is perforated to admit combustion air into the inner chamber. The combustion chamber has an outer wall defining an outer chamber. The outer wall is perforated to admit combustion air from a pressurized air plenum to the inner wall. The inner and outer wall are spaced apart such that air may flow between the inner and outer walls.

Abstract: A burner system for use in a gas cooking grill has a primary burner in a firebox providing heat to a cooking surface above the primary burner and a secondary burner in the firebox selectively providing heat to a cooking grate such that ignition of the secondary burner provides an additional degree of heat to the cooking surface above the primary burner.

Abstract: A medical device (100) includes an insulin pen (102), a pen needle (104) and a force sensor (106). The device also includes a microprocessor (206) to receive a signal from the force sensor (106). Audible and/or visual indicators (218, 220) provide feedback to a user to encourage proper injection technique. The device may also include an adaptor assembly comprising a sensor housing (306) and a first sensor (304) within the sensor housing, and a transfer needle assembly (308), the transfer needle assembly providing a connection (310) for a pen needle, and providing a fluid conduit between the pen needle (312) and the insulin pen (302). A second force sensor (314) is associated with a thumb button of the insulin pen (302).

Abstract: A cooking grill has a firepot configured to burn pelletized fuel fed from an auger, a cooking grate above the firepot, and a double walled enclosure interposing the firepot and the cooking grate and containing and directing flow of combustion gases from the firepot up to the cooking grate.

Abstract: A needle hub (10) for a pen needle is provided with an enlarged surface for contact with the skin of a patient. The enlarged surface is provided with a surface having a dimension and shape to enable a needle or cannula to penetrate the skin to a desired depth and permit substantially the entire exposed length of the needle or cannula to penetrate the skin to the desired depth. The surface of the needle hub can be formed by an inner cone shaped member (26) forming a first contact surface with a surface area of about 1-5 mm2 and an outer ring (28) at a peripheral edge forming a second contact surface with a combined surface area of about 15 to 50 mm2.

Abstract: A control system for a pellet fueled cooking device includes at least two adjustable smokestacks selectively allowing combustion gases to escape from a cooking chamber, and an air adjustment mechanism being adjustable between a first position where air flow into a firepot is substantially blocked and a second position where airflow into the firepot is allowed.

Abstract: A needle-bearing hub for a pen needle is provided with a distal patient-facing side having an enlarged surface for contact with the subject's skin. The enlarged surface is provided with a radius of curvature that increases the likelihood that the needle reaches full injection depth when an injection is performed at an inclined angle with respect to the surface of the skin and with to the desired depth less discomfort to the patient.

Abstract: A floor and an upright sidewall formed from two vertically coaxial components, each component having a floor baffle with a plurality of floor openings defined therein, each floor retained within a respective upright sidewall with a plurality of sidewall openings defined therein. The floor openings and the sidewall openings cooperate between the two coaxial components such that flow of gases through the floor and upright sidewall of the baffle structure is controlled by rotation of the two vertically coaxial components relative to one another.

Abstract: Provided herein are compositions and methods for treating cancer, treating colitis associated with immune checkpoint inhibitor therapy, colonizing the microbiome, and/or restoring the microbiome, by administering compositions or food products to a subject.