Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system provides identification and quantification of space use at a sub room level of granularity.

Abstract: Provided herein are bifunctional compounds that bind a target protein (e.g., a selected protein) and/or induce ubiquitination for degradation of the target protein. In particular, provided are compounds that bind a bromodomain or bromodomain-containing protein (e.g., BET proteins) or histone methyltransferases (HMTs, e.g., enhancer of zeste homolog 1 (EZH1), or FKBP12) and can promote its degradation by recruiting it to the ubiquitin receptor RPN13 (e.g., RA190), for proteasomal degradation. Also provided are pharmaceutical compositions comprising the bifunctional compounds, methods of treating and/or preventing diseases (e.g., proliferative diseases, cancers, benign neoplasms, pathological angiogenesis, inflammatory diseases, and autoimmune diseases) and musculoskeletal diseases, and methods of inducing the degradation of a target (e.g., a target protein) by recruiting it to the ubiquitin receptor RPN13 of the proteasome in a subject by administering a compound or composition described herein.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system detects and tracks animal wellness.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system provides identification of common areas of dwell in a space.

Abstract: A tool, such as a tape measure, including a spring-based retraction system is shown. Various spring-based retraction system embodiments are configured to decrease the size occupied by the spring within the tape measure housing, which consequently reduces tape measure housing size providing a more compact tape measure. Various spring-based retraction system embodiments are configured to control retraction of the tape measure in a manner that reduces whip or otherwise controls tape blade retraction. Some retraction system embodiments utilize a reduction gear train, and others utilize a compression spring and a transmission system that converts rotational movement of the tape reel to axial movement, which compresses the spring.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system provides identification of common movement pathways within a space.

Abstract: A system and method for proximate network antennas disposed in cavities in a portion of a seat is disclosed that provides ways to bring antennas closer to the bodies of seat occupants to improve signal to noise ratio and, therefore, throughput and capacity, and to use the bodies of seat occupants to attenuate the signals to improve channel re-use.

Abstract: A computer vision system includes a camera that captures a plurality of image frames of a target field of view; a processing unit coupled to the camera, the processing unit is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera and relay the outputs of those computations to a database on a set of servers, the database is connected to a web accessible user interface which allows users to view and interact with the data as well as add data and information that is stored in the database and visualized via the interface. The system provides identification and quantification of group formation.

Abstract: The disclosure provides compounds of the formula I and the pharmaceutically acceptable salts thereof. The variables, e.g. R1, R2, R3, R4, A, B, J, V, W, M, J and Ar are defined herein. The disclosure also provides pharmaceutical compositions comprising a compound or salt of formula I and a pharmaceutically acceptable carrier, methods of inhibiting dihydrofolate reductase (DHFR) in vitro or in vivo with a compound or salt of formula I, and methods of treating a bacterial infections, fungal infections, and protozoal infections with a compound or salt of formula I. A compound or salt of formula I can be the first and only active ingredient used in a pharmaceutical composition or method of this disclosure or may be combined with one or more additional active ingredients that are not compounds or salts of formula I.

Abstract: Various embodiments include methods and systems to dilute a sampled particle-laden aerosol stream in a recirculating type of aerosol diluter system. In one embodiment, a system to dilute a sampled aerosol stream includes an aerosol sample inlet. A primary diluter device includes a first inlet to receive the aerosol stream and a second inlet to receive a filtered portion of the aerosol stream and combining the filtered portion with an additional sampled aerosol stream. A flow diverter device splits at least the sampled aerosol stream into a first portion of the sampled aerosol stream and a remaining portion of the sampled aerosol stream. A filter receives the remaining portion of the sampled aerosol stream and provides a filtered aerosol stream to the second inlet of the primary diluter device. Other methods and apparatuses are disclosed.

Abstract: An apparatus includes a base that includes a raised surface and a first opening through the raised surface. The apparatus also includes a cover configured to be coupled to the base in order to form a cavity, where the cover includes a second opening through the cover. The raised surface is configured to allow passage of a first portion of optical energy through the first opening and to reflect a second portion of the optical energy. Portions of the cover and the base surrounding the cavity are configured to absorb the reflected second portion of the optical energy. The base may further include one or more baffles positioned around the raised surface, and/or the cover may further include one or more baffles positioned around the second opening.

Abstract: A handrail mountable wireless components installation apparatus and related method of installation are disclosed. The apparatus/method includes a shell having two parts, a wireless components housing and a lid; and a chassis for the fixedly but detachable mounting within the shell of the wireless electronic components necessary to provide a WiFi signal, as for example a router and an antenna, the chassis equipped with two sets of brackets. One set of brackets provides the anchoring means for the fastening of the lid onto the housing. The second set of brackets allows the enclosure to be mounted on the handrail. Optionally, the chassis is provided with a mounting plate for the mounting of a router and an opening capable of accommodating an antenna without impeding the flow of the antenna signal. Optionally, the weather resistant handrail mountable wireless components installation apparatus also comprises a gasket.

Abstract: Disclosed are methods for producing steviol glycosides, such as rebaudioside D and rebaudioside M, using engineered yeast. The methods include growing yeast on non-fermentative carbon sources. Other methods include growing yeast on one or more polysaccharides in which saccharification and fermentation of the polysaccharides occurs simultaneously.

Abstract: A handrail mountable wireless components installation apparatus and related method of installation are disclosed. The apparatus/method includes a shell having two parts, a wireless components housing and a lid; and a chassis for the fixedly but detachable mounting within the shell of the wireless electronic components necessary to provide a WiFi signal, as for example a router and an antenna, the chassis equipped with two sets of brackets. One set of brackets provides the anchoring means for the fastening of the lid onto the housing. The second set of brackets allows the enclosure to be mounted on the handrail. Optionally, the chassis is provided with a mounting plate for the mounting of a router and an opening capable of accommodating an antenna without impeding the flow of the antenna signal. Optionally, the weather resistant handrail mountable wireless components installation apparatus also comprises a gasket.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system provides physical security coaching.

Abstract: This disclosure relates to immunogenic peptides that are specific to B-cell maturation antigen (BCMA) and Transmembrane activator and CAML interactor (TACI), and methods of use thereof.

Abstract: The present disclosure relates to inhibitors of USP7 useful in the treatment of cancers, and other USP7 mediated diseases, having the Formula: wherein R1, R2, R3, R4, R5, R6, and n are described herein.

Abstract: Disclosed are methods for producing steviol glycosides, such as rebaudioside D and rebaudioside M, using engineered yeast. In some embodiments, the methods include fermenting with a yeast at a high pH such as of about 5.8 or greater. In some embodiments, the methods can be carried out by first growing the yeast at a lower first pH, and then adjusting the pH to a higher pH.

Abstract: The application relates to a compound of Formula (I) which modulate the amount of STK4, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease or disorder associated with the modulation of STK4.