Abstract: A combustion pre-chamber device for a spark ignition internal combustion engine is configured to engage a spark plug and be mounted to a cylinder head in communication with a combustion chamber of a cylinder of the engine. The combustion pre-chamber device includes any one or combination of a number of features to improve operating effectiveness, including extending the combustion operating range by improving cooling and optimizing the flow field inside the combustion pre-chamber device.

Abstract: The invention relates to combinations comprising an HDAC inhibitor and an immunomodulatory drug for the treatment of multiple myeloma in a subject in need thereof. The combinations may, optionally, further comprise an anti-inflammatory agent, such as dexamethasone. Also provided herein are methods for treating multiple myeloma in a subject in need thereof comprising administering to the subject an effective amount of one of the above combinations.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system detects and tracks animal wellness and habitat/intervention design.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system provides identification of intensity of movement pathways within a space.

Abstract: A cable junction enclosure is described that provides new and improved ways of managing hybridized cable connections. The cable junction enclosures described herein include means for managing fiber cable and means for managing copper cable that originate in a single-sheathed hybridized cable. The cable junction enclosure described herein provides a more efficient way to manage multiple types of cable from a hybridized cable while providing increased security and protection for cables contained therein, entering thereto, and exiting therefrom.

Abstract: Disclosed arc methods of releasing or enriching for steviol glycosides produced by yeast. The disclosed methods enhance or improve the release or enrichment of the steviol glycosides.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system detects people, identification of their location in a field of view as well as their actual physical location in a space detects.

Abstract: A method for additive manufacturing of a composite object containing a bonded network of boron carbide particles and aluminum occupying spaces between boron carbide particles, the method comprising: (i) producing a porous preform constructed of boron carbide by an additive manufacturing process in which particles of boron carbide are bonded together; and (ii) infiltrating molten aluminum, at a temperature of 1000-1400° C., into pores of said porous preform to produce said composite object constructed of boron carbide particles within an aluminum matrix, wherein the boron carbide is present in the composite object in an amount of 30-70 wt. %. The resulting composite material is also herein described.

Abstract: Some embodiments of the present invention include a suture anchor with both knotless and knotted suture attachment capabilities, as well as methods for loading the suture in knotless and knotted configurations. Some embodiments of the present invention include a suture anchor with an inner implant body with a spreader that slides in relation to an outer expandable collar, such that pushing the expandable collar distally with an inserter causes the spreader to expand the collar against the surrounding bone to secure the suture anchor in place. Such embodiments may also include a detachment or breakaway feature between the inserter and the suture anchor to permit separation after anchor deployment. Some embodiments of the present invention include methods for deploying such suture anchors and expanding the expandable collars and/or detaching the inserter tools. Embodiments of the present invention may be used in various orthopedic applications such as, for example, shoulder repair.

Abstract: The beverage brewing device, which is configured for use with a beverage brewer having an inlet probe for dispensing water and an outlet probe, includes a body defining a brew chamber configured to contain a dry beverage medium and at least one outlet probe receptacle extending upwardly from a bottom surface of the body. The outlet probe receptacle is sized and configured to receive an outlet probe of a beverage brewer. A lid is removably securable to the body and is engageable with the body to selectively enclose a top opening of the body. An inlet probe opening is defined in the lid for receiving an inlet probe of the beverage brewer. At least one filter is defined within in the body, wherein the filter is configured to retain a dry beverage medium within the brew chamber while allowing a brewed beverage to pass through the brew chamber.

Abstract: Systems and methods for controlling transmission of digital content stored at a server are disclosed. According to at least one embodiment, a method includes: receiving, at the server, session information from a device, the session information including information for authorizing the server to decrypt the digital content for transmission to a playback device; determining, at the server, to decrypt the digital content for the transmission to the playback device, based on the session information; decrypting, at the server, the digital content for the transmission to the playback device, in response to determining to decrypt the digital content; and transmitting, at the server, the decrypted digital content to the playback device.

Abstract: Various aspects of the disclosure relate to modular sill systems for sliding panel doors and windows, collectively “sliding fenestration units.” In various examples, modular sill systems include multiple separate and distinct base components that provide tracks on which one or more panels are able to slide.

Abstract: Disclosed herein are compositions and methods for treating neoplastic diseases. Included are compositions and methods that are effective against multiple myeloma cells resistant to conventional and bortezomib treatment. Furthermore, combination treatment with two different proteosome inhibitors is shown to be synergistic for treating multiple myeloma.

Abstract: A computer vision system includes a camera that captures a plurality of image frames in a target field. A user interface is coupled to the camera. The user interface is configured to perform accelerated parallel computations in real-time on the plurality of image frames acquired by the camera. The system identifies the dimensions of a space from only a picture and a user input reference marker.

Abstract: Stabilized cutting tool assemblies. A cutting tool assembly for use with a reference surface includes a tool holder having a rotational axis. The tool holder is arranged for attachment to a drive source arranged to rotate the tool holder and move the tool holder relative to a reference surface. The cutting tool assembly includes a rotatable cutting tool coupled to the tool holder. The cutting tool includes a cutting surface and has a first portion and a second portion. The first portion is disposed adjacent the tool holder. The cutting tool assembly includes a stabilizer coupled to the cutting tool adjacent the second portion. The stabilizer has a bearing surface. The bearing surface is positioned on the second portion to abut the reference surface and to stabilize the cutting tool when the drive source moves the tool holder and the cutting tool to a position adjacent the reference surface.

Abstract: A flow splitter may include an inlet, at least two outlets, and an internal vane comprising a first end corresponding to the inlet and a second end corresponding to the at least two outlets, wherein the internal vane is configured to turn, between the first end and the second end, an internal flowing fluid from 0 degrees to a degree between about 60 degrees and 150 degrees. Methods of dividing fluid flow are also provided.

Abstract: A surface-treating article, comprising a circular substrate (100) comprising a first major surface, an abrasive disposed on the first major surface, the abrasive having a first concentration at a first radius (110) measured from the center of the substrate, the abrasive having a second concentration not equal to the first concentration at a second radius (120) measured from the center of the substrate, wherein the first radius (110) and the second radius (120) are different lengths.

Abstract: The subject matter disclosed herein is generally directed to novel CD8+ tumor infiltrating lymphocyte (TIL) subtypes associated with response to immunotherapy treatment. Specifically, the subtypes are associated with checkpoint blockade therapy. Moreover, the subject matter disclosed herein is generally directed to methods and compositions for use of the subtypes. Also, disclosed herein are gene signatures and markers associated with the subtypes and use of said signatures and markers. Further disclosed are therapeutic methods of using said gene signatures and immune cell subtypes. Further disclosed are pharmaceutical compositions comprising populations of CD8+ TILs enriched for a specific subtype.

Abstract: A shielded ignition configuration is provided comprising a non-shield spark plug having an electrode, a spark plug extender having first end configured to mount to the spark plug such that a conductor of the extender makes electrical contact with the spark plug electrode, a second end having a cup configured for connection to a secondary lead such that the conductor makes electrical contact with the secondary lead, and a flange, and at least one retainer configured to engage the flange and cause a lower surface of the flange to engage an upper surface of a valve cover.