Abstract: The invention concerns ether derivatives of the formula IQ.sup.1 --X--Ar--Q.sup.2 IwhereinQ.sup.1 is an optionally substituted 9-, 10- or 11-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur;X is oxy, thio, sulphinyl or sulphonyl;Ar is optionally substituted phenylene, pyridinediyl, pyrimidinediyl, thiophenediyl, furandiyl, thiazolediyl, oxazoiediyl, thiadiazoiediyl or oxadiazolediyl; andQ.sup.2 is selected from the groups of the formulae II and III: ##STR1## wherein R.sup.1 is hydrogen, (2-5C)alkanoyl or optionally substituted benzoyl;R.sup.2 is (1-4C)alkyl; andR.sup.3 is hydrogen or (1-4C)alkyl;or R.sup.2 and R.sup.3 are linked to form a methylene, vinylene, ethylene or trimethylene group;or a pharmaceutically-acceptable salt thereof;processes for their preparation; pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors.

Abstract: Adjustable refrigerator shelving includes a shelf rail for supporting a partial width shelf within a refrigerated compartment on first and second, spaced shelf tracks vertically oriented in the compartment. The tracks releasably engage with a number of support brackets for cantilevered support of one or more shelves at a plurality of vertically spaced locations. The shelf rail is adapted for releasable engagement with the shelf tracks and is interposed between the partial shelf and the shelf tracks for horizontally adjustable support of the partial shelf. The shelf rail includes rearwardly projecting hooks at each of two opposing ends for releasable engagement with the shelf tracks. Locking tabs may be included on the hooks to retain the shelf rail on the tracks, while a rub strip is provided between the partial shelf and the shelf rail, along a top edge of the shelf rail.

Abstract: A molded refrigerator shelf useful for containment of spills on the shelf includes a planar shelf member with a rim molded around the perimeter edge of the shelf member to form a liquid tight seal between the rim and the shelf member. The molded rim projects above the top surface of the shelf member to form a liquid dam for containing spills to the shelf member. In one form, the shelf is slideably mounted to allow horizontal extension of the shelf and convenient access to the rear portion of the shelf using slide guides molded into the rim along each side of the shelf. The shelf is cantilevered upon support brackets from the rear wall of a refrigerator to allow air flow around the shelf sides. The support brackets are adapted to support the shelf at a plurality of vertical positions.

Abstract: A two-dimensional array (2) of imaging elements (3) is arranged in rows and columns. Each imaging element (3) has a two terminal component (40) for sensing light incident on the imaging element and for storing charge representing the incident light. A plurality of row and column conductors (5 and 6) are provided with one of the two terminals (4a,4b) of each component (40) in a row being coupled to the associated row conductor (5) and the other one of the two terminals (4a,4b) to the associated column conductor (6). Voltage signals are applied to the row and column conductors (5 and 6) for enabling the components (40) to sense light incident on the array (2) and to enable charge stored at a selected imaging element (3) to be sensed. The rows of imaging elements (3) are arranged in first and second sets (S1 and S2). A voltage signal of one polarity is applied to a row conductor (5) associated with the first set (S1) to enable charge stored at an imaging element (3) in the associated row (5) to be sensed.

Abstract: A semiconductor memory device includes an array of rows and columns of field effect transistors (FETs) which provide memory locations. The FET gate electrodes in each row are connected to a respective row conductor and the FET first and second main electrodes in each column are connected to respective adjacent column conductors so that the second main electrodes in one column are connected to the first electrodes of the FETs in any adjacent column. Circuitry is provided for storing data at and reading data from the memory locations. The circuitry stores data at a desired memory location by applying a first predetermined voltage V.sub.g.sup.W to a selected row conductor and a second predetermined voltage V.sub.d.sup.

Abstract: An electronic matrix array device such as a data store, e.g. a datacard, or an electro-optic active matrix display, has crossing sets of row and column conductors and matrix elements such as memory or picture cells at the crossing intersections. At least some of the matrix elements include a two-terminal thin film non-linear impedance element which may be bi-directional, such as a MIM, or unidirectional, such as a diode. The array device also includes a row address decoder for addressing the row conductors and a column address decoder for addressing the column conductors, either or both decoders having respective stages for respective conductors of the relevant set of conductors.

Abstract: In an opto-electronic memory system having a memory element (14), for example an optical data card, in which optically-encoded data is stored in rows of memory locations (17) and reading elements (10,12) comprising a photosensitive element array (12) and operable to read out stored data in response to illumination of the memory locations, data is stored at memory locations as colors representing different data values and the memory locations are addressed with reading light of different colors in sequence, thereby enabling higher data storage capacities to be obtained. The memory locations may be reflective or transmissive. The reading elements may comprise linear or two dimensional arrays of photosensitive elements.

Abstract: A staircase that is collapsible and hinged to the side of a vehicle allowing it to be folded up against the side of the vehicle for travel on roads. A pair of guide rods are connected at one end to the vehicle and at the opposite end to staircase for stabilizing the staircase when it rests upon an uneven ground. A pin is attached to the vehicle and can be inserted through a hole in the staircase locking the staircase when folded up.

Abstract: A combined matrix display and light sensing device comprising arrays of display elements (12) and light sensing elements (18) connected to a first set of address conductors (14) to which scan signals (15) are applied, a second set of address conductors (16) through which data signals from a drive circuit (30) are supplied to the display elements (12) and to which a detection circuit (40) is connected to detect illumination of sensing elements. The detection circuit comprises charge sensitive amplifier circuits (45) which serve also as buffer amplifiers for data signals from the drive circuit (30). Each circuit (45) comprises an output, a first input connected to a conductor of the second set, a second input, and a switch (48) and capacitor (47) connected in parallel between the output and the first input.

Abstract: A molded refrigerator shelf useful for containment of spills on the shelf includes a planar shelf member with a rim molded around the perimeter edge of the shelf member to form a liquid tight seal between the rim and the shelf member. The molded rim projects above the top surface of the shelf member to form a liquid dam for containing spills to the shelf member. In one form, the shelf is slideably mounted to allow horizontal extension of the shelf and convenient access to the rear portion of the shelf using slide guides molded into the rim along each side of the shelf. The shelf is cantilevered upon support brackets from the rear wall of a refrigerator to allow air flow around the shelf sides. The support brackets are adapted to support the shelf at a plurality of vertical positions.

Abstract: The invention concerns a heterocyclene derivative of the formula I ##STR1## wherein Ar.sup.1 is optionally substituted phenyl, naphthyl or a 9- or 10-membered bicyclic heterocyclic moiety;A.sup.1 is a direct link to X.sup.1 or (1-3C)alkylene;X.sup.1 is oxy, thio, sulphinyl, sulphonyl or imino;Ar.sup.2 is optionally substituted 5-membered heterocyclene moiety;R.sup.1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; andR.sup.2 and R.sup.3 together form a group of the formula --A.sup.2 --X.sup.2 --A.sup.3 -- which, together with the carbon atom to which A.sup.2 and A.sup.3 are attached, defines a ring having 5 to 7 ring atoms, wherein each of A.sup.2 and A.sup.3 is (1-3C)alkylene and X.sup.2 is oxy, thio, sulphinyl or sulphonyl;or a pharmaceutically-acceptable salt thereof.The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.

Abstract: The image sensor (1a) has a transparent substrate (2) supporting a two dimensional array (3) of photosensitive and switching elements (4) with switching signal conductors (5) and data signal conductors (6) connected to the photosensitive and switching elements (4) for enabling individual photosensitive elements to be accessed. The photosensitive and switching elements (4) and the conductors (5 and 6) are arranged such that at least half of the area of the image sensor is transparent during operation. Each photosensitive element is electrically coupled to a respective capacitor (7) for storing charge generated as a result of light being incident on the photosensitive element. The capacitors (7) are formed so as to be transparent and so as to occupy a significant part of the entire area of the array (3).

Abstract: The invention concerns oxime derivatives of the formula I ##STR1## wherein R.sup.4 includes hydrogen, carboxy, carbamoyl, amino, cyano, trifluoromethyl, (1-4C)alkylamino, di-(1-4C)alkylamino and (1-4C)alkyl;R.sup.5 includes hydrogen, (1-4C)alkyl, (3-4C)alkenyl, (3-4C)alkynyl, (2-5C)alkanoyl, halogeno-(2-4C)alkyl and hydroxy-(2-4C)alkyl;Ar.sup.1 is phenylene or a heteroaryl diradical;A.sup.1 is a direct link to X.sup.1, or A.sup.1 is (1-4C)alkylene;X.sup.1 is oxy, thio, sulphinyl or sulphonyl;Ar.sup.2 is phenylene or a heteroaryl diradical;R.sup.1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; andR.sup.2 and R.sup.3 together form a group of the formula -A.sup.2 -X.sup.2 -A.sup.3 - which together with the carbon atom to which A.sup.2 and A.sup.3 are attached define a ring having 5 or 6 ring atoms, wherein each of A.sup.2 and A.sup.3 is (1-3C)alkylene and X.sup.

Abstract: The invention concerns a heterocyclene derivative of the formula I ##STR1## wherein Ar.sup.1 is optionally substituted phenyl, naphthyl or a 9- or 10-membered bicyclic heterocyclic moiety;A.sup.1 is a direct link to X.sup.1 or (1-3C)alkylene;X.sup.1 is oxy, thio, sulphinyl, sulphonyl or imino;Ar.sup.2 is optionally substituted 5-membered heterocyclene moiety;R.sup.1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; andR.sup.2 and R.sup.3 together form a group of the formula --A.sup.2 --X.sup.2 --A.sup.3 -- which, together with the carbon atom to which A.sup.2 and A.sup.3 are attached, defines a ring having 5 to 7 ring atoms, wherein each of A.sup.2 and A.sup.3 is (1-3C)alkylene and X.sup.2 is oxy, thio, sulphinyl or sulphonyl; or a pharmaceutically-acceptable salt thereof.The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.

Abstract: The invention concerns a diaryl ether cycloalkane of the formula I, or a pharmaceutically-acceptable salt thereof, ##STR1## wherein Ar.sup.1 is optionally substituted phenyl or naphthyl; X.sup.1 is oxy, thio, sulphinyl or sulphonyl;Ar.sup.2 is optionally substituted phenylene, or a 6-membered heterocyclene moiety containing up to three nitrogen atoms;R.sup.1 is (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl, cyano-(1-4C)alkyl or (2-4C)alkanoyl, or optionally substituted benzoyl; andR.sup.2 and R.sup.3 together form a (3-6C)alkylene group which defines an optionally substituted ring having 4 to 7 ring atoms.The invention also concerns processes for the manufacture of a diaryl ether cycloalkane of the formula I, or a pharmaceutically-acceptable salt thereof, and pharmaceutical compositions containing said cycloalkane. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.

Abstract: cDNA clones coding for the chicken cysteine proteinase inhibitor cystatin were found and isolated using for example a synthetic oligonucleotide probe corresponding to amino acids 81-90 of the cystatin sequence. This was used to screen a lambda gt 11 chicken oviduct cDNA library. A full length cystatin cDNA was also isolated.

Abstract: The invention concerns a diaryl ether heterocycle of the formula I, or a pharmaceutically-acceptable salt thereof, ##STR1## wherein Ar.sup.1 is optionally substituted phenyl or naphthyl;X.sup.1 is oxy, thio, sulphinyl or sulphonyl;Ar.sup.2 is optionally substituted phenylene, or a 6-membered heterocyclene moiety containing up to three nitrogen atoms;R.sup.1 is (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl, cyano-(1-4C)alkyl or (2-4C)alkanoyl, or optionally substituted benzoyl; andR.sup.2 and R.sup.3 together form a group of the formula --A.sup.2 --X.sup.2 --A.sup.3 -- wherein each of A.sup.2 and A.sup.3 is (1-4C)alkylene and X.sup.2 is oxy, thio, sulphinyl, sulphonyl or imino.The invention also concerns processes for the manufacture of a diaryl ether heterocycle of the formula I, or a pharmaceutically-acceptable salt thereof, and pharmaceutical compositions containing said heterocycle. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.

Abstract: A carrier tape comprising a strip of flexible material having a series of spaced through openings and a predetermined thickness, the size of the openings and the predetermined thickness being adapted to receive a component between the major surfaces of said strip. The strip of flexible material comprises a layer of nonwoven thermoplastic polymeric fiber adhered together and has in the range of 20 to 70 percent air filled open spaces between the fibers.

Abstract: The invention concerns a diaryl ether cyclic ether of the formula I, or a pharmaceutically-acceptable salt thereof, ##STR1## wherein Ar.sup.1 is optionally substituted phenyl or naphthyl;X.sup.1 is oxy, thio, sulphinyl or sulphonyl;Ar.sup.2 is optionally substituted phenylene, or a 6-membered heterocyclene moiety containing up to three nitrogen atoms;R.sup.1 and R.sup.2 together form a group of the formula --A.sup.2 --X.sup.2 --A.sup.3 -- wherein each of A.sup.2 and A.sup.3 is (1-4C) alkylene and X.sup.2 is oxy, thio, sulphinyl, sulphonyl or imino; andR.sup.3 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl and substituted (1-4C)alkyl.The invention also concerns processes for the manufacture of a diaryl ether cyclic ether of the formula I, or a pharmaceutically-acceptable salt thereof, and pharmaceutical compositions containing said cyclic ether. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.

Abstract: A carrier tape comprising a strip of flexible material having a series of spaced pockets and a predetermined thickness, the size of the pockets and the predetermined thickness being adapted to receive a component between the major surfaces of said strip. In a preferred embodiment the pockets have at least a substantially closed base portion which lies between the major surfaces of the strip. The strip of flexible material comprises a layer of nonwoven thermoplastic polymeric fiber adhered together and has in the range of 20 to 70 percent air filled open spaces between the fibers. The strip of flexible material may also be composed of a thermoplastic foam.