Abstract: Components, such as a cutting element for an earth-boring drilling tool include an ultrasonic transducer coupled therewith, and configured to transmit an acoustic signal therethrough, and transmit a data signal to a data acquisition unit in response to receiving a returning echo of the acoustic signals. An earth-boring drilling tool, comprises a bit body including a plurality of components, an ultrasonic transducer, and a data acquisition unit operably coupled with the ultrasonic transducer. The data acquisition unit may be configured to receive the data signal and determine a temperature distribution of the component based, at least in part, on a time-of-flight of the acoustic signals and the returning echoes. Methods for forming such components and measuring a temperature of such components may relate to coupling and implementing such an ultrasonic transducer with a component of an earth-boring drilling tool.

Abstract: A method and system for identifying and discouraging predatory and uncompetitive sales practices includes identifying at least one base cost for at least one product, determining at least one current cost for the at least one product from at least one retailer displaying or selling products and services through online or mobile channels, and determining if the at least one product sold by the at least one retailer displaying or selling products and services through online or mobile channels is a loss-leader based at least partially on the at least one base cost and the at least one current cost. At least one of the at least one product may be automatically purchased from the at least one retailer displaying or selling products and services through online or mobile channels if the at least one product sold by the at least one retailer is determined to be a loss-leader. A system for implementing the aforementioned method includes appropriately communicatively connected hardware components.

Abstract: The present invention comprises a system and method for providing three-dimensional and maintaining digital design rights management. The invention comprises a first server computer configured to transmit, to user terminals, images associated with three-dimensional designs. The server receives at least one request, from at least one user terminal, to fabricate one or more three-dimensional objects from three-dimensional designs. A second server computer in communication with the first server computer, and located remotely from the first server computer is controlled by an entity that does not control the at least one first server computer. The second server computer is configured to store design specifications associated with three-dimensional designs and control a fabricating device in communication with the at least one second server computer.

Abstract: The present invention relates to novel heterocyclic compounds as Fatty Acid Binding Protein (FABP) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose.

Abstract: A patient alignment system for a radiation therapy system. The alignment system includes multiple external measurement devices which obtain position measurements of components of the radiation therapy system which are movable and/or are subject to flex or other positional variations. The alignment system employs the external measurements to provide corrective positioning feedback to more precisely register the patient and align them with a radiation beam. The alignment system can be provided as an integral part of a radiation therapy system or can be added as an upgrade to existing radiation therapy systems.

Abstract: Apparatus and methods for therapy delivery are disclosed. In one embodiment, a therapy delivery system includes a plurality of movable components including a radiation therapy nozzle and a patient pod for holding a patient, a patient registration module for determining a desired position of at least one of the plurality of movable components, and a motion control module for coordinating the movement of the least one of the plurality of movable components from a current position to the desired position. The motion control module includes a path planning module for simulating at least one projected trajectory of movement of the least one of the plurality of moveable components from the current position to the desired position.

Abstract: The present invention describes pyrimidine compounds of Formula I that are useful as anaplastic lymphoma kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods of using the same.

Abstract: A drill bit made according to one embodiment includes a source configured to induce radiation into a formation during drilling of a wellbore and a sensor in the drill bit configured to detect radiation from the formation responsive to the radiation induced by the source. The drill bit may further include a circuit configured to process signals received from the sensor to estimate a property of the formation.

Abstract: A system and method for active remediation and/or passive protection against cyber attacks includes an active remediation and passive protection server computer for monitoring at least a portion of network data between at least one first network and at least one second network to detect one or more attacks and/or unauthorized access to at least one first agent in the at least one first network by at least one second agent in the at least one second network. The active remediation and passive protection server computer executes at least one of (i) one or more active remediation mechanisms to actively respond to the one or more detected attacks and/or unauthorized access and (ii) one or more passive protection mechanisms to passively protect against the one or more detected attacks and/or unauthorized access.

Abstract: In a process for the transalkylation of polycyclohexylbenzenes, a feed containing at least one polycyclohexylbenzene is contacted with benzene under transalkylation conditions with a catalyst comprising a zeolite USY having a silica to alumina molar ratio in excess of 10 to convert at least part of said polycyclohexylbenzene to cyclohexylbenzene.

Abstract: A method, system, and computer program product for intelligent command prediction are provided. The method includes determining a command prediction preference associated with a user from user profile data, and selecting one or more command history repositories responsive to the command prediction preference. The one or more command history repositories include command history data collected from a plurality of users and classification data associated with the plurality of users. The method also includes calculating command probabilities for commands in the command history data of the selected one or more command history repositories as a function of the classification data associated with the plurality of users in relation to the user. The method additionally includes presenting a next suggested command as a command from the command history data of the selected one or more command history repositories with a highest calculated command probability.

Abstract: The present invention provides Fused Tricyclic Compounds of the Formula (I) wherein Q, R1, R2, R3, and R4 are as defined herein, and pharmaceutically acceptable salts of such Fused Tricyclic Compounds. The Fused Tricyclic Compounds are useful in the treatment of cancer and other proliferative disorders.

Abstract: The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.

Abstract: A method is described for preparing a molecular sieve-containing catalyst for use in a catalytic process conducted in a stirred tank reactor. The method comprises providing a mixture comprising a molecular sieve crystal and forming the mixture into catalyst particles having an average cross-sectional dimension of between about 0.01 mm and about 3.0 mm. The mixture may include a binder and the catalyst particles are then calcined to remove water therefrom and, after calcination and prior to loading the catalyst particles into a reactor for conducting the catalytic process, the catalyst particles are coated with a paraffin inert to the conditions employed in the catalytic process.

Abstract: A drill bit made according to one embodiment may include a bit body having a longitudinal axis, a plurality of gamma sensors placed in the bit body, at least two gamma ray sensors in the plurality of sensors are spaced-apart from each other along the longitudinal axis of the bit body, wherein each such sensor in the plurality of sensors is configured to detect gamma rays from the formation during drilling of the wellbore and to provide signals representative of the detected gamma rays, and a circuit configured to process at least partially the signals from each of the at least two gamma ray sensors for estimating an inclination of the bit body relative to the longitudinal axis.

Abstract: A patient alignment system for a radiation therapy system. The alignment system includes multiple external measurement devices which obtain position measurements of components of the radiation therapy system which are movable and/or are subject to flex or other positional variations. The alignment system employs the external measurements to provide corrective positioning feedback to more precisely register the patient and align them with a radiation beam. The alignment system can be provided as an integral part of a radiation therapy system or can be added as an upgrade to existing radiation therapy systems.

Abstract: A technique is provided for capturing browsing history of a webpage. A processor receives a webpage from a server, determines that a trigger associated with a user is fulfilled, and captures a page of the webpage responsive to the trigger associated with the user being fulfilled.

Abstract: This disclosure relates to a process for hydrocarbon conversion comprising contacting, under conversion conditions, a feedstock suitable for hydrocarbon conversion with a catalyst comprising an EMM-10 family molecular sieve.

Abstract: In a process for producing cyclohexylbenzene, benzene and hydrogen are fed to at least one reaction zone comprising a catalyst system which comprises a molecular sieve and at least one hydrogenation metal. The MCM-22 family molecular sieve having an X-ray diffraction pattern including d-spacing maxima at 12.4±0.25, 6.9±0.15, 3.57±0.07 and 3.42±0.07 Angstrom, and the hydrogenation metal is selected from the group consisting of palladium, ruthenium, nickel, zinc, tin, cobalt, and combinations of any two or more thereof. Hydroalkylation conditions of temperature and pressure are selected to produce a hydroalkylation conversion in a range of from about 15% to about 75% The benzene and hydrogen are then contacted in the at least one reaction zone under said selected hydroalkylation condition to produce an effluent containing cyclohexylbenzene.

Abstract: Compounds of Formula (I) are useful inhibitors of anaplastic lymphoma kinase. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.